Medical Applications of Nanotechnology Gholamreza Pourmand, M.D.
What is nano? Power Prefix Origins 10 12 tera  teras: monster 10 9 giga  gigas: giant 10 6 mega  megas: large 10 3 kilo  c...
What is nanotechnology <ul><ul><li>Creation of functional materials, devices, and systems. </li></ul></ul><ul><ul><li>Cont...
Nanotechnology Growth S. Milunovich, J. Roy. United States Technology Strategy. Merrill Lynch. 4 Sept. 2001
How small is nano? Scale: Nanoscale $151,700:  1/100 th  cent Acre:  1/100 th  square inch Decade:  1/3 rd  second E. Corc...
Why is the nanometer scale different? <ul><ul><li>The wavelike properties of electrons inside matter are influenced by var...
Many Different Length Scales 10cm 1cm 100  m 1  m
Relative Size of Nanoparticles Nanoparticle with a 2 nm core and an octanethiol functionalized monolayer
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Smart Nanostructures for Selective Drug Delivery Scale: 1/40 th  of red blood cell Nanotube Nanocap Drug Delivery for: #1 ...
Targeted Delivery to Tumors
 
 
NanoMedical Diagnostics <ul><li>Targets: </li></ul><ul><ul><li>- drug overdose </li></ul></ul><ul><ul><li>- brain trauma <...
 
 
 
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Nanotalk last

  1. 2. Medical Applications of Nanotechnology Gholamreza Pourmand, M.D.
  2. 3. What is nano? Power Prefix Origins 10 12 tera teras: monster 10 9 giga gigas: giant 10 6 mega megas: large 10 3 kilo chilioi: thousand 10 -3 milli milli: thousand 10 -6 micro mikros: small 10 -9 nano nanos: dwarf
  3. 4. What is nanotechnology <ul><ul><li>Creation of functional materials, devices, and systems. </li></ul></ul><ul><ul><li>Control of matter on the nanometer (1-100 nm) length scale. </li></ul></ul><ul><ul><li>Exploitation of novel properties and phenomena developed at that scale. </li></ul></ul>
  4. 5. Nanotechnology Growth S. Milunovich, J. Roy. United States Technology Strategy. Merrill Lynch. 4 Sept. 2001
  5. 6. How small is nano? Scale: Nanoscale $151,700: 1/100 th cent Acre: 1/100 th square inch Decade: 1/3 rd second E. Corcoran. The Next Small Thing. Forbes Magazine , 07/23/01
  6. 7. Why is the nanometer scale different? <ul><ul><li>The wavelike properties of electrons inside matter are influenced by variations on the nanometer scale. </li></ul></ul><ul><ul><li>The systematic organization of matter on the nanometer length scale is a key feature of biological systems. </li></ul></ul><ul><ul><li>Nanoscale components have very high surface areas. </li></ul></ul><ul><ul><li>The finite size of material entities, determine an increase of the relative importance of surface tension and local electromagnetic effects. </li></ul></ul><ul><ul><li>The interaction wavelength scales of various external wave phenomena become comparable to the material entity size. </li></ul></ul>
  7. 8. Many Different Length Scales 10cm 1cm 100  m 1  m
  8. 9. Relative Size of Nanoparticles Nanoparticle with a 2 nm core and an octanethiol functionalized monolayer
  9. 25. Smart Nanostructures for Selective Drug Delivery Scale: 1/40 th of red blood cell Nanotube Nanocap Drug Delivery for: #1 - Cardiovascular disease #2 – Cancer #3 - Infectious diseases Toxin Removal for: Adverse drug reactions >106,000 deaths/yr Pesticide Poisonings >220,000 deaths/yr
  10. 26. Targeted Delivery to Tumors
  11. 29. NanoMedical Diagnostics <ul><li>Targets: </li></ul><ul><ul><li>- drug overdose </li></ul></ul><ul><ul><li>- brain trauma </li></ul></ul><ul><ul><li>- disease markers </li></ul></ul><ul><li>Where: </li></ul><ul><ul><li>- hospital </li></ul></ul><ul><ul><li>- law enforcement </li></ul></ul><ul><ul><li>- homeland security </li></ul></ul>
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