“ Although we do not know the absolute global figures, we do know that each year there are now at least 560,000 new MEDLINE articles including over 20,000 new randomized controlled trials. In daily terms, this means about 1500 new MEDLINE articles, including 60 randomized trials, being published every day ......Hence there is no shortage of research to read, but there is a shortage of time to read it.”
Glaziou, Paul. Managing the Evidence Flood. Surgical Clinics of North America 2006 86(1): 193-194.
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2. Selecting the right resource Use when… Source … you need all original research or when other resources fail you. PubMed/Ovid MEDLINE … you want reviews of individual clinically applicable original studies. ACP Journal Club … you have a therapy question and want comprehensive synthesis of all relevant RCTs. Cochrane Systematic Reviews … you need direction on current policy regarding diagnosis, therapy, or related clinical circumstances. National Guideline Clearinghouse … time is limited and no comprehensive review is sought. UpToDate