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Vitamin a and it’s deficiency
 

Vitamin a and it’s deficiency

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    Vitamin a and it’s deficiency Vitamin a and it’s deficiency Presentation Transcript

    • VITAMIN A AND IT’S DEFICIENCY
      DR. PARTH GURAGAIN
    • VITAMIN A AND IT’S DEFICIENCY
      Vitamin A constitute both retinol , which is a pre-formed vitamin and beta – carotine which is a pro- vitamin which is converted into retinol in intestinal mucosa. The international unit is used for the measurement , IU.
      1IU= 0.3MICROGRAMS OF RETINOL.
    • FUNCTIONS
      Required for normal vision. It helps in production of retinal pigments required in dim light.
      It helps in maintaining the integrity and normal functioning of glandular and epithelial tissue which lines intestinal, respiratory, urinary tract plus in skin and eyes.
      It supports skeletal growth.
      It is anti-infective.
      It may protect against epithelial cancer (Bronchial Cancer)
    • SOURCES
      VITAMIN A
      Animal source (pre-formed vitamin-Retinol)
      Plant source (pro-vitamin -Carotene)
      Animal food- liver, egg, butter, cheese,whole milk, fish, meat.
      Plant food -green leafy vegetables (spinach, amarath), mango, papaya,pumpkin, carrot.
      Fortified food-vanaspati, margarine,milk.
    • DEFICIENCY
      Signs of vitamin A deficiency are mainly occular
      Night blindness
      Conjunctivalxerosis
      Bitot’s spot
      Corneal xerosis
      keratomalacia
    • Night blindness
      It is inability to see in dim light
      Mother is first to notice the condition in the child for most of the time.
      If vit A is not increased the condition will worsen.
      CONJUNCTIVAL XEROSIS
      Conjunctiva becomes dry and non-wettable.
    • Bitot’s Spot
      It is triangular ,pearly-white or yellowish foamy spot on the bulbar conjunctiva on either side of cornea.
      CORNEAL XEROSIS
      Cornea appears dry,dull and non-wettable and eventually opaque.
      Severe cases may lead to corneal ulceration.
      Ulcer heals leaving scar which may affect vision.
      KERATOMALACIA
      Liqueafication of cornea.
      Cornea may become soft and brust open.
      If eye collapse- vision is lost.
    • EXTRA-OCCULAR MANIFESTATION
      Follicular hyperkeratosis
      Anorexia
      Growth retardation
      Increase in morbidity and mortality due to respiratory and intestinal infection.
    • TREATMENT
      Early stage of Xeropthalmia
      2,00,000 IU of vit A orally in each successive day.
      PREVENTION
      By giving food rich in vitamin
      Decrease frequency of contributing disease- PEM, Diahorrea, respiratory infection
      Other forms-
      200000 IU of vit A every six-month (1-6 yrs)
      100000 IU of vit A every six-month (6 mth-1 yrs)
      RDA
      RDA for Vit A in adults is 600mg.
    • TOXICITY
      Nausea
      Vomitting
      Anorexia
      Sleep disorder
      Skin desquamation
      Liver enlargement
      Odema.