Dna protein
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Dna protein

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Dna protein Dna protein Presentation Transcript

  • DNA Transcription & Protein Translation Honors Biology SOL.BIO.6f
  • Today’s Objectives
    • TSW investigate and understand common mechanisms of protein synthesis.
  • DNA Transcription
    • DNA must be copied to messenger RNA (mRNA)
    • mRNA goes from nucleus to the ribosomes in cytoplasm
    • mRNA complements known as codons
      • Only 3 nucleotide “letters” long
    • Remember RNA has uracil (U) instead of thymine (T)!
    View slide
  • Transcription – Step I Template DNA Strands A C G T A T C G C G T A T G C A T A G C G C A T View slide
  • Transcription – Step II Template DNA is Matched Up with Complementary mRNA Sequences A C G T A T C G C G T A U G C A U A G C G C A U
  • Transcription – Step III mRNA leaves nucleus and goes to ribosomes A new complementary RNA strand is made (rRNA) U G C A U A G C G C A U A C G U A U C G C G U A
  • Transcription Reminders
    • The template strand is the DNA strand being copied
    • The rRNA strand is the same as the DNA strand except Us have replaced Ts
  • Protein Translation
    • Modified genetic code is “translated” into proteins
    • Codon code is specific, but redundant!
      • 20 amino acids
      • 64 triplet (codon) combinations
  • tRNA in cytoplasm has a codon attached to an amino acid
  • tRNA structure
    • 3-base code (triplet) is an “anticodon”
    • Protein molecule
    • Attached amino acid that is carried from cytoplasm to ribosomes
  • Protein Synthesis
    • Start: Ribosome binds to mRNA at start codon (AUG)
    • Elongation:
      • tRNA complexes bind to mRNA codon by forming complementary base pairs with the tRNA anticodon
      • The ribosome moves from codon to codon along the mRNA.
      • Amino acids are added one by one
    • Release: release factor binds to the stop codon
  •