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Velscope Presentation (Detailed)
 

Velscope Presentation (Detailed)

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    Velscope Presentation (Detailed) Velscope Presentation (Detailed) Presentation Transcript

    • ENHANCED ORAL ASSESSMENT
    • LOOK AGAIN
    • Neoplastic Lesions Normal Epithelium Hyperplasia Dysplasia Carcinoma In Situ Invasive Carcinoma Squamous Metaplasia Stage I - IV
    • ORAL CANCER & DYSPLASTIC PROGRESSION Mild Dysplasia Moderate Dysplasia Severe Dysplasia Potentially Malignant Disease Stages Ideal time for discovery & intervention is in the Premalignant stages Squamous Cell Carcinoma (SCC) Carcinoma-In-Situ (CIS)
    • TISSUE FLUORESCENCE AND DYSPLASTIC PROGRESSION Florescence intensity decreases with dysplastic progression. Breakdown of Collagen Matrix (prelude to invasion) Collagen cross-links ↓ Micro-Vascularization (recruitment of new blood supply) Inflammation Blood absorption ↑ Nuclear back-scattering ↑ Fluorophores excited ↓ Metabolic Activity ↑ FAD ↓ Fluorescence ↓ Fluorescence ↓ Fluorescence ↓ Fluorescence ↓
    • PHOTO DOCUMENTATION SOLUTIONS Digital Camera with Adaptor SLR Camera with Adapter VELscope Vx Camera System
    • SEE PREVENTION IN A NEW LIGHT VELscope Vx Camera System • 12 megapixel Canon® digital camera • USB cable for seamless connection to MAC and PC systems • Memory card, battery charger and battery pack • Quick twist on connection to VELscope Vx handpiece • Preconfigured settings for hassle free start up
    • NORMAL FLOOR OF THE MOUTH
    • BILATERAL PRESENTATION IS A GOOD THING
    • DYSPLASIA & ORAL CANCER Images courtesy of the British Columbia Oral Cancer Prevention Program.
    • FLUORESCENCE VISUALIZATION Copyright ® 2002-2007 by Oral Health Study, Oral Oncology/Dentistry, BCCA Clinical Appearance (Visible Under White Light) Loss of Fluorescence Carcinoma-In-Situ (CIS)
    • PRE-CLINICAL DISCOVERY Images courtesy of the Dr. Samson Ng. Clinical Appearance (Visible Under White Light) Loss of Fluorescence 34 year-old male presents with ‗funny‘ feeling on palate
    • DYSPLASIA & ORAL CANCER Images courtesy of the British Columbia Oral Cancer Prevention Program. Clinical Appearance Loss of Fluorescence Region of CIS is now clearly visible Mild dysplasia CIS Mild dysplasia
    • SEVERE DYSPLASIA ON ALVEOLAR RIDGE Images courtesy of the University of Washington Oral Medicine Program. Clinical Impression: Denture Trauma? Inflammation resolved in 2 weeks after removal of denture Excisional Biopsy: Severe Dysplasia
    • Visible Leukoplakia Irregular, Dark Area Images courtesy of the University of Washington Oral Medicine Program Visible Leukoplakia Normal Fluorescence Pattern Patient referred for biopsy. Result: Negative. Patient referred for biopsy. Result: Severe dysplasia.
    • VELscope CAN ALSO DISCOVER THESE CONDITIONS: • Lichen Planus • Lichenoid mucositis • Squamous Papillomas • Candidiasis • Viral and bacterial infections • Inflammation from a variety of causes (e.g. trauma) • Salivary gland tumors
    • Inflammatory Response & Trauma
    • Non-cancerous lesions where biopsy is recommended for definitive diagnosis: • Erosive Lichen Planus • Benign Mucous Membrane Pemphigoid (BMMP) • Pemphigus Vulgaris • Erythema Multiforme • Non-resolving Traumatic Ulcer • Tuberculosis Lesions • Histoplasmosis • Necrotizing Sialometaplasia • Squamous Papilloma • Verruca Vulgaris • Verruciform Xanthoma • Condyloma Acuminatum • Focal Epithelial Hyperplasia • Foreign Body Gingivitis • Plasma Cell Gingivitis • White Sponge Nevus • Chronic Hyperplastic Candidiasis • Actinic Chelitis • Pyogenic Granuloma • Peripheral Giant Cell Granuloma • Peripheral Ossifying Fibroma • Fibroma • Epulis Fissuratum • Mucocele • Ranula • Parulis • Actinomyosis • Lipoma • Hemangioma • Lymphangioma • Neuroma • Neurofibroma • Lymphoid Hyperplasia • Oral Lymphoepithelial cyst • Gingival Cyst • Chelitis Glandularis • Benign Salivary Gland Neoplasm • Drug-induced gingival hyperplasia • Leukemic Gingival Infiltrate • Kaposi‘s Sarcoma • Melanocytic Nevus • Melanotic Macule
    • 19 OF THE 20 PATIENTS SHOWED DYSPLASIA OR CANCER BEYOND THE CLINICALLY VISIBLE LESION Images courtesy of the British Columbia Oral Cancer Prevention Program.
    • Two consecutive years of screening everyone (over 12 yrs old) in the practice. A decidedly low-risk population, right? Year ONE – Visible Light only: – ZERO pre-malignant lesions found. – ZERO ―success‖ rate with biopsy referrals. – 25% ―success‖ rate with brush biopsy. Year TWO – VELscope added to protocol: – TEN pre-malignant lesions found. – 83% ―success‖ rate with biopsy referrals. – 100% ―success‖ rate with brush biopsy. WITH TEN PRE-MALIGNANT LESIONS!
    • Study at TATA Memorial Hospital, Mumbai In a recent study conducted at Tata Memorial Hospital (Mumbai), Velscope® was used to obtain fluorescence images from 261 sites in the oral cavity from 76 patients and 90 sites in the oral cavity from 33 normal volunteers. From the results of the study, it was concluded that the performance of Velscope® which is a simple, objective low-cost system has the potential to improve oral screening efforts, especially in low resource settings.
    • Velscope Clinical Data – Early Stage Cancer Diagnosis JCDA Sept 2007, Vol. 73, No. 7 Clin Cancer Res, Cancer Prev Res Nov 2006, Vol 12, Issue 22 2009;2(5) May 2009 General Dentistry Jan/Feb 2009 • Impressive new findings for VELscope Vx: – Recent 620-patient study at University of Washington found that 11.1% of patients had lesions only detected by the VELscope exam. • In addition to oral cancers and precancers, VELscope Vx was powerful in detecting: – Viral, fungal and bacterial infections – Inflammation – including lichen planus, other lichenoid reactions – Squamous papillomas – Salivary gland tumors Results from 50 biopsies taken from areas with loss of fluorescence in 44 patients showed a sensitivity of 98% and specificity of 100% for discriminating normal tissue from severe dysplasia, carcinoma in situ or invasive carcinoma, using histology as the gold standard.
    • NEW CLINICAL STUDIES • Impressive new findings for VELscope Vx: – Recent 620-patient study at University of Washington found that 11.1% of patients had lesions only detected by the VELscope exam. • In addition to oral cancers and precancers, VELscope Vx was powerful in detecting: – Viral, fungal and bacterial infections – Inflammation – including lichen planus, other lichenoid reactions – Squamous papillomas – Salivary gland tumors
    • VELscope ENDORSEMENTS • June 30, 2010 – World Health Organization recognizes VELscope Vx as ―an innovative device‖ that addresses global health concerns. – 1 of 8 commercial devices to be so honored. – The only dental device to be honored. • AGD – partnership with LED Dental / VELscope – 12 oral cancer screening courses with CDE. – Includes advertising for VELscope Vx. • University of Washington study led by Dr. Ed Truelove – Impressive new findings with use of VELscope Vx by GPs. – Clear case for expanded/routine usage in clinical practice. • Many NA teaching hospitals and over 100 thought leaders are ―VELscope lovers.‖
    • VELscope Vx • Supporting Preventive Health Care • Preserving Quality Of Life • Improving Clinical Decisions • Helping Build Dental Practices • Maybe Even Saving A Life A “Win-Win” For The Patient And The Practice
    • VELscope Vx • There are many reasons to feel good about giving your patients regular enhanced oral soft tissue exams (featuring both white light and VELscope Vx screenings) – You‘re taking actions that most practices aren‘t. – You‘re giving your patients—and yourself—peace of mind. – You‘re letting patients know that you care about their health. – It won‘t disrupt your practice. • The two exams take 5 minutes combined. • The VELscope Vx exam is free of rinses, dyes and discomfort. – You‘re using a proven adjunctive technology trusted for millions of exams – You‘ll significantly increase your bottom line. – You‘ll reduce the risk of lawsuit. – YOU JUST MIGHT SAVE A LIFE OR TWO!