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SWAN, HyQue and Nanopublications

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Claim #1: Intramembranous Aβ behaves as chaperones of other membrane proteins

Claim #1: Intramembranous Aβ behaves as chaperones of other membrane proteins

An example of application of the nanopublications approach to represent AlzSWAN content.

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SWAN, HyQue and Nanopublications SWAN, HyQue and Nanopublications Presentation Transcript

  • AlzSWAN, HyQueand nanopublications
    An example:
    Claim #1: Intramembranous Aβ behaves as chaperones of other membrane proteins
    Paolo Ciccarese, PhD
    February 25, 2011
  • A claim taken from AlzSWAN
    URL: http://tinyurl.com/4h2am3a
  • The claim by the author in SWAN
    rdf:type
    <http://tinyurl.com/4h2am3a>
    swande:Claim
    dct:title
    Intramembranous Aβ behaves as chaperones of other membrane proteins
    swan-de: http://purl.org/swan/2.0/discourse-elements/
    dct: http://purl.org/dc/terms/
    View slide
  • Claim in a graph with authorship
    rdf:type
    <http://tinyurl.com/4h2am3a>
    swande:Claim
    dct:title
    Intramembranous Aβ behaves as chaperones of other membrane proteins
    G1
    pav:authoredBy
    <http://example.info/person/1>
    G2
    rdf:type
    foaf:name
    Vincent Marchesi
    foaf:Person
    pav: http://purl.org/pav/provenance/2.0/
    foaf: http://xmlns.com/foaf/0.1/
    View slide
  • Adding provenance [1]
    rdf:type
    <http://tinyurl.com/4h2am3a>
    swande:Claim
    dct:title
    Intramembranous Aβ behaves as chaperones of other membrane proteins
    G1
    pav:curatedBy
    <http://example.info/person/0>
    G3
    rdf:type
    foaf:name
    Gwen Wong
    foaf:Person
  • Adding provenance [2]
    rdf:type
    <http://tinyurl.com/4h2am3a>
    swande:Claim
    dct:title
    Intramembranous Aβ behaves as chaperones of other membrane proteins
    G1
    pav:authoredBy
    <http://example.info/person/1>
    G2
    pav:curatedBy
    <http://example.info/person/0>
    G4
    rdf:type
    foaf:name
    Gwen Wong
    foaf:Person
  • Author’s evidence
    rdf:type
    <http://tinyurl.com/4h2am3a>
    swande:Claim
    dct:title
    Intramembranous Aβ behaves as chaperones of other membrane proteins
    G1
    swanrel:referencesAsSupportiveEvidence
    <http://example.info/citation/1>
    G5
    pav:contributedBy
    <http://example.info/person/1>
    G6
  • Adding provenance
    G1
    swanrel:referencesAsSupportiveEvidence
    <http://example.info/citation/1>
    G5
    pav:contributedBy
    <http://example.info/person/1>
    G6
    pav:curatedBy
    <http://example.info/person/0>
    G7
  • Translating the claim into HyQue-triples
    <http://example.info/alzswan:statement_f3556dcfc331d9b9af9d5c0cfc570ba6_event_1>
    Event of type GO "chaperone binding"
    rdfs:label
    rdf:type
    <http://bio2rdf.org/go:0051087>
    <prefix:actor_1>
    <http://bio2rdf.org/chebi:53002>
    rdf:type
    rdfs:label “Beta amyloid”
    <prefix:target_1>
    <http://bio2rdf.org/mesh:D008565>
    rdf:type
    rdfs:label “Membrane protein”
    <http://bio2rdf.org/go:0005886>
    <prefix:location_1>
    rdf:type
    rdfs:label “Plasma membrane”
    G8
    Triples provided by Nigam Shah
  • Adding the provenance
    Hyque triples
    G8
    pav:contributedBy
    <http://example.info/person/2>
    G9
    rdf:type
    foaf:name
    Nigam Shah
    foaf:Person
  • Connecting SWAN Claim and Hyque triples
    rdf:type
    <http://tinyurl.com/4h2am3a>
    swande:Claim
    dct:title
    Intramembranous Aβ behaves as chaperones of other membrane proteins
    G1
    swanrel:derivedFrom
    G8
    Hyque triples