Building a world class university prof. barry halliwellPresentation Transcript
Elsevier Forum on Accelerating Research Excellence New Delhi, India 23 September 2011 BUILDING AWORLD CLASS UNIVERSITY Professor Barry Halliwell Tan Chin Tuan Centennial Professor Deputy President (Research & Technology) National University of Singapore
THE NATIONAL UNIVERSITY OF SINGAPORE NUS Research is good and has improved fast in recent years Evidence for Impact• Bibliometic indices and league tables• Success in grant competition (e.g. 3.5/5 Research Centres of Excellence)• Growing new industries for Singapore and developing existing ones. Extensive EDB investment in NUS and visits by foreign companies.• Consultancies and other advisory positions to industry and government bodies• The investment by government, charities, industry etc into NUS to create “think tanks”, such as Risk Management Institute, Centre for International Law, VISA, Real Estate Studies, Centre for Maritime Studies, LKY School of Public Policy etc• Location of selected high-level industries at NUS, e.g. Siemens, GE, SDWA
DO RANKINGS MATTER?THEY ARE FLAWED BUT PEOPLE DO NOTICE THEM(including prospective staff and students)
Field Cites per Paper Rank (% above / below world average)(This measures the % by which the research impact is above the world average) NUS Field 2006- 2000-2010 2010 Materials Science +101 +132 Agricultural Sciences +69 +104 Mathematics +48 +42 Engineering +35 +50 Pharmacology & Toxicology +33 +44 Chemistry +26 +34 Computer Science +8 +27 Environment/Ecology +6 +32 Circles represent where impact has grown significantly over the Biology & Biochemistry +5 +22 past 5 years as opposed to 10 years. Clinical Medicine -7 +12 Source: Thomson Reuters/Essential Science Indicators
World University Ranking 2010 THE vs QS Times Higher Education NUS QS World University NUS (THE) World University Ranking Ranking 2010 2010 2011 World Rank 34 World Rank 31 28 Ranking in Asia Region 4 Ranking in Asia Region 3 3 Overall Score 72.9 Ranking by Discipline Teaching 65.5 Engineering and IT 9 NA International Mix 97.8 Life Sciences and 13 NA Biomedicine Industry Income 40.5 Social Sciences 16 NA Research 72.6 Arts and Humanities 23 NA Citations 78.7 Natural Sciences 25 NASource :http://www.topuniversities.com/university-rankings/world-university-rankingshttp://www.topuniversities.com/university-rankings/asian-university-rankingshttp://www.timeshighereducation.co.uk/world-university-rankings/
WHY DO WE STUDY RANKINGS?• They HELP to tell us that NUS Research is good and has improved fast in recent years (but we don’t judge this only by ranks and citations)• Bibliometric indices and league tables• Success in grant competition (e.g. 3.5/5 Research Centres of Excellence)• Growing new industries for Singapore and developing existing ones. Extensive EDB investment in NUS and visits by foreign companies.• Consultancies and other advisory positions to industry and government bodies• The investment by government, charities, industry etc into NUS to create “think tanks”, such as Risk Management Institute, Centre for International Law, VISA, Real Estate Studies, Centre for Maritime Studies, LKY School of Public Policy etc• Location of selected high-level industries at NUS, e.g. Siemens, SDWA, Agilent, ZeissComments from the External Review Panel for the Quality Assurance Frameworkfor Universities 2010• The ERP commends NUS for the progress made in research since 2004 in terms of obtaining a head start in developing peaks of excellence, getting more funding and producing more and higher impact publications.• They HELP us to identify up and coming researchers and successful research fields (“peaks of excellence”), as well as under-performing areas• They can help identify productive collaborations with other Institutions.
Singapore: Transportation Hub and Entry to Asia (Planes and Ships) South Korea Japan Middle East China India Bangladesh Hong Kong Taiwan Thailand Vietnam USA Europe Sri Lanka Philippines Malaysia Australia Singapore BruneiAdvantages • No energy (except some solar) New Zealand• Location • Little food• Political / social stability • Little space Indonesia• Good government • No oil or mineral resources• People • Water-constrained • Climate change • Very small, minute domestic market • Rapidly ageing population
NUS: Singapore’s National and OnlyComprehensive UniversityA KEY FUNCTION OF NUS IN SINGAPORE IS TO PROVIDE ASTRONG AND BROAD (YET RELEVANT) RESEARCH BASE• Lord Krebs in his evidence to the House of Commons Innovation, Universities, Science and Skills Committee (2008-9) pointed to a study in which ten key advances in cardiovascular medicine were traced back to about 600 papers from 400 different disciplines which provided the basis for the advances. Over 40% of them had nothing to do with cardiovascular medicine at all and many of them were not carried out in medical departments but in departments of chemistry, engineering, physics, botany, agriculture, zoology etc. A vision for UK Research, Council for Science and Technology (2010)• Several Agency for Science, Technology and Research (A*STAR) RICs had their origins in NUS.
Research is conducted in All Major Disciplines Faculties and Schools (Undergraduate and Graduate education) 1. Arts and Social Sciences 7. Law 2. Business 8. Medicine 3. Computing 9. Music 4. Dentistry 10. Science 5. Design and Environment 11. University Scholars Programme (for Undergraduate only) 6. Engineering Graduate Schools 1. Duke-NUS Graduate Medical School 2. Lee Kuan Yew School of Public Policy 3. NUS Graduate School for Integrative Sciences and Engineering
ADVANTAGES OF NUS Comprehensive Infrastructure & Proximity KENT RIDGE CAMPUS Dentistry GE Water DMERI Zeiss Engineering Science Nursing SIEMENS LILLY Agilent Medicine Singapore- Delft Water Alliance Computing Temasek Life Centre for Life National University Sciences Sciences Hospital Laboratory Humanities / Social New MRT Sciences
ADVANTAGES OF NUS *Occupants MIT SINGAPORE’S NATIONAL AND ONLY ETH Zurich TUM Munich COMPREHENSIVE UNIVERSITY Imperial College Synergy in Proximity Hebrew University Technion Israel SMART / Berkeley CREATE Peking University Biopolis / NRF* NUS NTU Others Fusionopolis National University SICS Hospital NEW one-north MRT! Map courtesy of Singapore JTC Corporation Science Parks 11SICS – Singapore Institute for ClinicalScience (A*STAR)
A Problem NUS hasStudents Enrolled – Type (AY 2010-11) Graduate Students Undergraduate 10,548 (<50% local) StudentsType of Graduate Total 26,418ProgrammesCoursework - 4721 (80% local)Masters 28.5%Coursework – 281 Total Research in honours yearGrad. Diploma Research in junior yearsCoursework – 196 36,966 (UROP)DoctoralResearch – 1052 71.5%MastersResearch – PhD 4298Total 10548 No Large Rise in Numbers PlannedNumber of PhD Students is increasing fast
BUT RESEARCH NEEDS MONEY! 92% OF NUS RESEARCH IS EXTERNALLY-FUNDED Type of research Typical quantum1. Investigator-led project based 50k – 1 million*2. Programme 5-25 million3. University-level institute / centre Variable, often 3-50 million4. Research Centre of Excellence 150 million *The backbone and enabler that allows a PI to build research programmes and prepares them to eventually participate in bigger programmes
NUS STRATEGY1. High-level (yet relevant) research over a reasonably broad base from which “peaks of excellence” grow (BUT HOW DO WE IDENTIFY THEM?)2. Synergy across boundaries to achieve research impact and bid for strategic funding3. Work with agencies in Singapore to utilise NUS research to address real-world questions4. Partner strategically with overseas institutions for the same reason5. Work closely with industry for mutual benefit
RESEARCH AT NUSInterdisciplinarity is strongly encouraged - Department / Faculty based - Faculty Research Centres - Cross-Faculty Clusters - Research Centres of Excellence - Cross Institution Clusters HOW DO WE ENCOURAGE THIS? 1. Dialogue 2. Space 3. Resources (a little money, some space, allocation of scholarships for graduate students)
ADVANTAGES OF NUS University Level RICs 24½ University-level Research Institutes or Centres • Asia Research Institute • Life Sciences Institute • Centre for International Law • Middle East Institute • Centre for Maritime Studies • NUS Environmental Research Institute • Centre for Remote Imaging, Sensing & • NUS Nanoscience & Nanotechnology Processing Initiative • East Asian Institute • Risk Management Institute • Energy Studies Institute • Singapore Synchrotron Light Source • NUS Global Asia Institute • Solar Energy Research Institute of • Institute for Mathematical Sciences Singapore • Institute of Real Estate Studies • Temasek Laboratories • Institute of South Asian Studies • The Logistics Institute-Asia Pacific • Interactive & Digital Media Institute • Tropical Marine Science Institute Advantages Status, access to resources (seed funding), SPACE, ability to bid for large external grants
Research Centres of Excellence (RCEs)3.5 / 5 (70% success rate)Centre for Quantum Technologies • Singapore’s first RCE established in 2007 • Conducts interdisciplinary theoretical and experimental research into the fundamental limits of information processing • $158 million over 10 years from National Research Foundation (NRF) and the Ministry of Education (MOE)Cancer Science Institute of Singapore • Set up in March 2008 to become one of the world’s leading centres for cancer research • $172 million over 7 years from NRF and MOEMechanobiology Institute, Singapore• Established in September 2009• Work on new ways of studying diseases through the mechanisms of cell & tissue mechanics• Funding of $150 million over 10 years from NRF and MOESingapore Centre on Environmental and Life Sciences Engineering• NTU-led RCE with substantial NUS input; to be operational by January 2011• Conducts cutting edge research on microbial biofilm communities for water and environmental sustainabilityBUT HOW TO SUPPORT THEM WHEN THE MONEY RUNS OUTAFTER 7-10 YEARS?
NUS STRATEGYSynergise across boundaries / Encourage mixing CONTROL SPACE CAREFULLY!T-Lab Building NORTH WING TEMASEK LABORATORIES@NUS SOUTH WING L9 Director’s & Admin OfficeL11 NUSNNI-NanoCore L8 Seminar Rooms, Library etc.L9 & 10Mechanobiology L7 EM Materials LabInstitute, SingaporeL7 & 8 Div of Env Sci L6 Office Space & Engineering L5 Office SpaceL6 NUS-GE S’pore Water Tech Centre L4 Control / Computational /L5 Seminar Rooms, Cognitive Science Labs Office Space L4 Data Centre L3 Antenna & EM Material LabL2 NUS Environmental L2 Aeroscience LabResearch Institute
STRENGTHS OF NUS CLOSE LINKS WITH AGENCIES IN SINGAPORE TO APPROACH REAL-WORLD QUESTIONS School of Design and Environment • More than S$12 million worth of research projects funded primarily from the Ministry of National Development Research Fund. • Research projects conceptualized and implemented in collaboration with agencies such as the Urban Redevelopment Authority (URA), Housing and Development Board (HDB), National Parks Board (NParks), Building and Construction Authority (BCA) and the Land Transport Authority. • Projects include subjects such as BCA’s zero energy building, evaluation of Greenmark buildings, benchmarking city sustainability, density-environment relationships, urban climate mapping, urban greenery and urban space designs, and transport modeling. • Research outcomes have high impact on public sector policies on land use, urban planning, urban redevelopment, transportation, biodiversity and housing. • Will work closely with ETH and other overseas partners • Will link closely with VISA NUS Environmental Research Institute (NERI) / Tropical Marine Science Institute (TMSI) • Close links with PUB, other public bodies, and Industry BUT BE CAREFUL THAT YOU DO NOT BECOME TOO NARROWLY- APPLIED
NUS ALSO STRONGLY SUPPORTSRESEARCH IN HUMANITIES / SOCIALSCIENCES / LAW / BUSINESS• Important in its own right, e.g. to develop understanding and explanations of human conditions and behaviour.• Contributes to cross-disciplinary initiatives (environment, sustainability, digital media, ethics, risk management, ageing etc)• Holistic education of students
ONE EXAMPLE The Biology of Decision Making under Risk • Research project headed by Prof Richard Ebstein (Psychology, NUS) and Prof Chew Soo Hong (Economics, NUS) • Awarded €507,000 by the AXA Research Fund. • AXA Research Fund first grant to an Asian University • Conventional wisdom (‘nothing ventured nothing gained’) is clear on the importance of taking risks but the source of the individual differences observed in risk taking remains obscure. • The proposal aims to understand these individual differences employing cutting edge methods from the neurosciences, psychology, experimental economics and human genetics. • Hypothesis : Decision making under risk, albeit a complex behavioral phenotype, can be understood as a basic biological mechanism with roots embedded in evolution and genetics.
Centre for International Law (CIL)History: Officially launched on 30 October 2009 by Senior Minister Prof S. Jayakumar.Founding Director: Assoc Prof Robert C BeckmanVision: To become a regional intellectual hub and thought leader for research on and teaching ofinternational lawFocus areas: ASEAN Law and Policy; Ocean Law and Policy; Economic Law and Policy; Aviation Law andPolicy; and International Dispute Resolution.Promoting thought leadership through policy-relevant conferences, workshops and speaker series.Examples: • Regional Workshop on Submarine Telecommunications Cables and Law of the Sea • Global Conference on International Investment Arbitration • International Conference on Air Transport, Air Law and Regulation • The CIL ASEAN Charter Series • Regional Workshop on International Maritime Crime (upcoming)Research that promotes Singapore’s and Asia’s influence on International Law developments. Examples: • ASEAN Integration Through Law (ITL) Research Project • The CIL Documents Database (currently over 450 ASEAN and International Law documents available for easy, free download) • Submarine Telecommunications Cables and the Law of the Sea Research ProjectCapacity-building and training for government officials. Examples: • CIL Executive Programme on the conduct of international economic disputes • CIL Executive Programme on anti-dumping legislation for economic officials • CIL Executive Programme on investment law for trade officials (upcoming) • International Law training course for diplomats at the Ministry of Foreign Affairs Diplomatic Academy http://www.cil.nus.edu.sg
ONE CONSEQUENCE NUS CAN NURTURE NICHE AREAS OF HIGH QUALITY THAT ARE NOT YET THE “FLAVOUR OF THE MONTH” [e.g. non-medical biology, plant science, humanities and social science (e.g. Asia Research Institute), mathematics] One example • Molecular basis of crop yields (MOU signed with the International Rice Research Institute (IRRI) on 16 Feb 2009) • Crop resistance to environmental change • Nutrition, diet and health maintenance in Asians • Biodiversity • New competitive grants from NRF and SMF (3 grants totalling $21.2 million were obtained in the food security area)
HOW DOES NUS WORK?
THE GANG OF FIVE President Deputy President Deputy President Deputy President (Academic Affairs) (Research & CEO (Administration) & Provost Technology) NUS Enterprise • The Provost, also a Deputy President, is responsible for all academic matters in the University. • The Deputy President (Research & Technology) (DPRT) oversees the University’s research programmes and its University-level Research Institutes and Centres, including RCEs. • The Deputy President (Administration) is in charge of the central administrative departments of the University. • NUS Enterprise was established to promote enterprise at NUS. The CEO of NUS Enterprise works closely with DP(R&T) and oversees all entrepreneurial and commercial activities of the University.
Duties of DP(R&T) Office - Administration and Compliance Promote NUS-Industry Exchange - Facilitation GrantGrant Seed Administration Matching Grant Dialogue with Funding Scheme Funders Identify Areas of Strategic Importance High Impact Growing Research the Pie Promote Multidisciplinary Research Programmes Attract & Retain Talent Build solid base of high-quality research across a reasonably-broad range of disciplines Research Strong Global Benchmarking Establish Research Centres of Excellence ProfileReview within NUS & other Peaks of International Researchand relative to peer Excellence in selected areasuniversities(researchbenchmarking) Recognition & Establish International Facilitate Commercialisation Research Networks of Research Outcomes Research Reward of Research Spin Off Excellence Publicise Achievements IP Protection Protection of Research Prestigious Research Awards Integrity Animal Welfare Institutional Review Board (IACUC)
How to Grow Research Quality?• Quality staff (its all about people)• Give them the conditions they need to excel• Accurate and fair (real and perceived) assessment of performance• NUS operates performance based pay (salary rises, performance bonuses)• Criteria for promotion and tenure require performance in teaching and research (excellent in one, good in the other)• Quality graduate students allocated to the best people• Taking advantage of funding opportunities• Selective allocation of NUS resources to support excellence Money Students Space
Supporting NEW Ideas and NEW People• Light teaching loads for new staff• Young Investigator award (substantial additional start-up package)• Cross-Faculty rapid grant award• Research fund for Arts and Social Sciences• Assistance with grant-writing
NUS Young Investigator Award(NUS YIA)Grant: ≤ S$500k in addition to usual start-up packagesDuration: ≤ 3 yearsAim: Support early career development of young faculty members likely to make significant contributions to the development of research at NUS Encourages projects that cross traditional disciplinary boundaries or break new groundCriteria: PI must be a full-time academic staff at an NUS Faculty/School PI must have joined NUS within the past 3 years PI must be less than 40 years old
SMF-NUS Research Horizons Award• Co-funded by NUS and the Singapore Millennium Foundation (SMF)• Seeks to accelerate the development of paradigm- changing research ideas from conception to implementation.• Winners will have one year and funding of up to S$100,000 each to carry out their investigations.• At the end of the term, they will compete for the Phase II funding of up to S$1 million over two years if their ideas show promise.(based on Bill and Melinda Gates award scheme)
Expanding Cross-Disciplinary Research• To seed the “programmes of the future” and encourage interactions• Investigators from two different Faculties/Schools (junior staff preferred as PIs)• One year funding of up to S$35,000• Not restricted to strategic areas (quality of project, quality of staff, innovation are key parameters)• Rapid decision process• Special allocation for research in ageing
A POTENTIAL PROBLEMClose to 92% of NUS Research Funds come from External Competitive GrantFunds, often for 2-3 year projects (Data for Y2009) Others (Other Min/Stat NUS-funded Research Boards/Industry/ Foundations/ Programmes Individuals) 4% RCEs (Cancer, CQT, MOE Block Grant for Others (Other Min/Stat Mechanobiology) Research (Tier 1) Boards/Industry/ 4% Foundations/ Individuals) MOH 28% NRF (Projects) 9% A*STAR TOTAL $402m MOE Competitive Grants (Tier 2) MOE Competitive Grants (Tier 2) 7% NRF (other than RCE funding) RCEs (Cancer, CQT, Mechanobiology) MOE Block Grant for A*STAR Research (Tier 1) 18% 15% MOH 15% NUS-funded Research ProgrammesNote:(i) MOE also provides a research scholarship block but graduate students require research support in order to be trained. If this is included as external grant income the % rises to 93.5%.(ii) NUS-funded Research Programmes refer to NUS Young Investigator Award, Cross Faculty Grant, Humanities & Social Sciences-funded projects, Start-up Fund and other programmes funded from ODPRT. THIS MAKES US VERY VULNERABLE TO CHANGES IN THE FUNDING LANDSCAPE.
SOME COMING THREATS• Inappropriate metrics (e.g. immediate application, number of patents, licensing income)• Insufficient funds for investigator-led research• Insufficient indirect cost support (or equivalent)
International Alliance of ResearchUniversities (IARU)IARU members are leading research universities that share a globalvision, similar values and a commitment to educating future worldleaders.The 10 members are:• Australian National University• ETH Zurich• National University of Singapore• Peking University• University of California, Berkeley• University of Cambridge• University of Copenhagen• University of Oxford• The University of Tokyo• Yale University
Research at NUS addressesSingapore Problems LOOKING FORWARD - be ahead of the pack Challenges Facing Singapore Energy (more efficient usage, securing supply) Environmental management / global warming Risk of infectious diseases Securing the food supply / human nutrition Ageing and age-related disease World insecurity / financial risks in Asia Sustainable cities NUS AND SINGAPORE AS TEST-BEDS FOR SUSTAINABLE URBAN SOLUTIONS
A COMING PROBLEM FOR SINGAPORE Proportion of population aged 65+ in selected IARU countries UK DK AUST 2030 2005 SG 1980 JP CH 0 5 10 15 20 25 30 35REUTERS/CORBIS Slide by courtesy of Dr Kenneth Howse, OxfordCentenarians now constitute the Universityfastest-growing age group owing to Source: UN Population databaseadvances in health care. The International Alliance of Research Universities (IARU) is a collaboration between ten of the world’sSource – Nature 467 (2010), 274- leading research-intensive universities who share275 similar visions for higher education, in particular the education of future leaders. IARU comprises ANU, ETH Zurich, NUS, Peking, Berkeley, Cambridge, University of Copenhagen, Oxford, University of Tokyo and Yale University.
(Virtual) Institute for the Study of Ageing (VISA) Anti-aging medicine (ethical) Basic aging / Neurobiology research Health care delivery / outcomes Ageing & Lifestyle (nutrition, exercise etc) Social aspects (e.g. community support) Housing for the aged Public policy (e.g. pensions) Products for the aged Dementia centre City design (e.g. public transport) Gerontology group NUS Schools and Faculties / Research Institutes/ Centres Dementia Centre Singapore Institute Human studies for Clinical Subject cohorts Sciences VISA Mild cognitive impairment Human studies (NUHS) Lifestyle and disease Industry liaison prevention Translational medicine/ Optimal environment nutritional products (ageing in place) Thought leadership for Government and Social sciences Basic Science charities Humanities Disease-related Public policy research Tsao Foundation Cognitive assessment Duke-GMS (NUHS) Global Asia LKY SPP Institute Financial / risk Exploring the identity management of the 21st century Asia city Healthcare policies Financing the elderly
What does VISA aim to do?• Biological determinants of ageing well• Environments that best support ageing well• Fiscal, medical & other policy issues that can be optimised to better support Singaporean ageing population
Interdisciplinary Research,the Sustainability ClusterNUS Environmental Research Institute (NERI)Formed to harnass our multiple ongoing research programmes inseveral Schools/Faculties to address major issues.Major Research Directions(1) Water, Air & Land;(2) Human & Environmental Health.(3) Energy SystemsCentre for Sustainable Asian Cities(School of Design and Environment)To maintain Singapore as an excellent and functional liveable city
Sustainability Cluster (Profs Tan Thiam Soon, Ong Choon Nam, Peter Ng) Powerful cluster : good dialogue with funding agenciesNUS Global Asia InstituteCentre for Sustainable Asian CitiesEnergy Studies InstituteSolar Energy Research Institute of SingaporeEnergy @ NUS InitiativeCentre for Total Building PerformanceEnergy Sustainability UnitAsia-Pacific Centre for Environmental LawInstitute of Water Policy / Other aspects of public policy (LKYSPP)NUS Environmental Research InstituteTropical Marine Science InstituteCentre for Offshore Research and EngineeringMinerals, Metals & Materials Technology CentreSustainable Energy Materials and SystemsRaffles Museum of Biodiversity ResearchBiodiversity programmeCentre for Hazards ResearchNUS Schools and Faculties 40
Energy and Environment Cluster Powerful cluster : Energy Office now (Prof Tan Thiam Soon) One-stop office on Energy Research, Energy Energy Office @ NUS Directions, and Energy Education in NUS Exploratory NUS Global Asia Institute (GAI) NUS President’s initiative on Research and Scholarship directed at topics pivotal to Asia’s future Science Solar Energy Research Institute of Singapore Singapore’s national institute for Applied Energy (SERIS) Research Energy Studies Institute (ESI) A national policy-research institute in Energy policies (economics, security and the environment) Future NUSNNI / FOE / FOS Research in areas of Solar Energy, Li-ion Batteries, Technology Sustainable Energy Materials & Systems Hydrogen Production & Storage and Fuel Cells Centre for Total Building Performance (CTBP) Research in Tropical Building Design, Construction, A BCA-NUS Centre for Tropical Building Maintenance and Management Research Policy To develop course structure and training syllabus forImplementation Energy Sustainability Unit (ESU) the Singapore Certified Energy Manager (SCEM) training programme NUS Environmental Research Institute (NERI) Interdisciplinary research, education and expertise in the environment affecting Singapore and Asia Office of Environmental Sustainability (OES) To effect a total shift to Environmental Sustainability Energy in all aspects of campus lifeSustainability Lee Kuan Yew School of Public Policy Areas of focus include Asian Energy Security and (LKYSPP) Energy Governance Singapore Institute of Nuclear Science & An initiative on Nuclear Science and Engineering Engineering Research (SINSER) programme Centre for Behavioural Economics To understand and improve Energy Usage Behaviours 41
NUS and SINGAPORE EXCEL IN MATERIALSSCIENCENUS NANOSCIENCE AND NANOTECHNOLOGY INITIATIVE(NUSNNII) / NANOCORE / SYNCHROTON LIGHT SOURCE /GRAPHENE RESEARCH CENTRE Research themes • Oxide Electronics • Spintronic materials • Graphenes • High density memories • Nm scale imaging and patterning • Charge transport in mesoscopic systems • Materials for sustainable energy • Nano drug delivery and diagnostics • Active plasmonics • Nanowire based device architectures • New imaging technologies
STRENGTHS OF NUS LIFE AND BIOMEDICAL SCIENCES CLUSTER How to make a gobal impact in a fiercely-competitive area? NUS Life Sciences Institute (LSI) NUS Centre for Life Sciences (CeLS) Competitive Space for Integrated Life Science Programmes
What is our TranslationalMedicine niche?• Preferred site in Asia for validation & testing of new diagnostics, drugs & devices in man for Asian diseases*• Deep expertise in disease biology and world-class Proof –of- Concept & early phase clinical trial capability with international accreditation• Close link of basic biomedical research, engineering, and computing with clinical medicine *Diseases more common in Asia, or diseases where symptoms, outcome, and pathology are different, as compared to the rest of the world.
Research Programmes in Life SciencesDisease-related themes Underpinning Science & Technology Cancer Molecular Epidemiology / Genetics Neurodegenerative disease Bioinformatics / Tissue Respository Vascular Diseases Bioengineering/ Neuroengineering / Infectious Diseases Tissue Engineering Human nutrition / disease Medicinal Chemistry / Toxicology / Clinical Trials revention Healthy ageing Structural Biology Environmental microbiology Immunology Lipidomics Psychology / human cognition Neuroscience, neuroengineering and cognition ALL CROSS-FACULTY, CROSS-DISCIPLINARY
Links to National University Hospital NUS Faculties of Engineering and Science, BIOPOLIS School of Computing A*STAR Physical & Computing Sciences NUS National Life Sciences Translational University Institute / CeLSSchools / Faculties Research Health System Tissue Repositories Translational Experimental Surgery Medical Centre Medical Imaging Molecular Pathology Investigational Medical Unit Bioengineering / Tissue Engineering / Neuroengineering Duke-GMS partnership Medical Ethics
National University Health System (NUHS) • NUS Yong Loo Lin School of Medicine • Alice Lee Centre for Nursing Studies • NUS Faculty of Dentistry • National University HospitalResearch goals• Generate multi-disciplinary, theme-based research• Establish proof-of-concept and efficacy in humans• Investigate the Asian phenotype• Implement health services researchExamples• Early diagnosis of gastric cancer Centre for Translational• Translational research in eye surgery Medicine (MD6)• Metabolic medicine and diabetes in Asians• Stroke types more common in Asia
Translational Research at theCentre for Translational Medicine (MD6) • 41,000 sqm • 15 floors: 9 floors for Research, 6 floors for Education • Clinical Imaging Research Centre • A BSL3 lab for complex work in Infectious Diseases • Investigational Medicine Unit • Cancer Science Institute, Singapore • Other major programmes, including cardiovascular medicine, neuro- cognition, immunology, and metabolic medicine (diabetes and obesity)
MAJOR NEW DEVELOPMENTS, INFRASTRUCTURE Opening of the MD2 Vivarium, a “state of the art” Green building Isolation (Illinois) Sterile Storage: 9000L Cubicle and Large Bulk Autoclave Animal Housing Dedicated Necropsy Large Holding Room for Room with Small Animals Ergonomic Equipment Dirty Side Cage Large Animal Operating Wash: Rack and Room Tunnel Washers
MAJOR NEW DEVELOPMENTS, INFRASTRUCTURE AAALAC (Association for Assessment and Accreditation of Laboratory Animal Care – International) • A private, nonprofit organization promoting the humane treatment of animals in science through a voluntary accreditation program, a program status evaluation service, and educational programs. • Comprised of professional life science societies and is not a governmental agency. • AAALAC is a voluntary peer-review process and certifies whether standards of excellence in institutional animal care programs are attained and maintained. • While 90% of the top 100 institutions receiving NIH funding are AAALAC accredited, only 45% of the institutions in Times Higher Education (THE) top 30 are AAALAC accredited. Seventy-five percent of the top 15 THE institutions are AAALAC accredited.
JOINT INTERNATIONAL RESEARCH (THE KI EXAMPLE) BREAST CANCER RESEARCH PROGRAMME Centre for Molecular Epidemiology Profound changes in breast cancer incidence may reflect changes into a Westernized lifestyle: a comparative population-based study in Singapore and Sweden. Int J Cancer. 2005 Jan 10;113(2):302-6. Variation in the seasonal diagnosis of acute lymphoblastic leukemia: Evidence from Singapore, the United States, and Sweden. Am J Epi. 2005; 162(8): 753-763 Do Asian breast cancer patients have poorer survival than their western counterparts? A comparison between Singapore and Stockholm. Breast Cancer Res. 2009;11(1):R4.
Singapore Peking Oxford Research Enterprise (SPORE) SPORE-T SPORE-M Technology Market- Transfer oriented SPORE-D technologySPORE is a S$63 million Disciplinary • Reduce, exploitation Reuse andinitiative supported by the Development recycle (3R) • Green • Highly technologiesNational Research Foundation • Master’s and concentrated • Ecocitythrough the Environment and Ph.D organic planning programmes wastewater (SinomenWater Industry programme • Executive (HCOW) technologies • River Ltd)office, NUS, Peking University, training ecological programmethe University of Oxford, rehabilitationcompetitive research grantsand industry partnerships. Slide by courtesy of Prof Ong Choon Nam
ASSESSING RESEARCHWHY IS ACCURATE ASSESSMENTNEEDED?• NUS OPERATES PERFORMANCE BASED PAY (salary rises, performance bonuses)• CRITERIA FOR PROMOTION AND TENURE REQUIRE PERFORMANCE IN TEACHING AND RESEARCH (Excellent in one, good in the other)• MINISTRY OF EDUCATION FUNDING INCREASINGLY HAS A “QUALITY FACTOR”• DECIDING WHERE TO INVEST CENTRAL RESOURCES TO CONVERT GOOD TO EXCELLENT TO ALLOW US TO BID FOR SUBSTANTIAL COMPETITIVE FUNDINGWHICH PEAKS OFEXCELLENCE TO GROW?
RESEARCH ASSESSMENT• Grant Income• Count Papers• Citations• Journal Tiering (Tier 1 and 2 papers)• Counting Patents / Licensing IncomePreviously a 6-page form had to be completed.
Assessing Research ImpactWhat research are you doing and why is it important?
NUS SEEKS TO CONDUCT IMPACTFULRESEARCHWHAT IS IMPACT OF RESEARCH?• Outstanding fundamental research of high intellectual impact that attracts attention to Singapore as a country capable of performing such research and grows NUS’ global reputation• Research which helps to grow new industries for Singapore and to develop existing ones, e.g. by spin-offs and licensing of Intellectual Property (IP)• Research that helps to attract high-level foreign industry to locate in Singapore• Research that makes Singapore a better place to live and improves the health and welfare of the population• Research that expands intellectual breadth and develops ideas and discourses about human experiences which will prepare us more effectively for an increasingly global and cosmopolitan world• Research that influences and informs government policy• Research that enhances the security of Singapore (e.g. defence, food, energy supply)Note that the best research programmes often contribute in several of these areas.
Journal Tiering • Introduced in 2001 by Provost Office • Benchmarking tool for institutional performance • Benchmarking tool to evaluate Dept/faculty performance against external institutions. • Reference list for academics seeking advice about quality journals to publish in. • Four categories Premium (Tier 1) – 10% Leading (Tier 2) – 20% Reputable (Tier 3) – 25% Others (Tier 4) – 45% • The default is to list by subject-related impact factor plus “special factors”.* HERE LIES THE DEVIL!
Background of Journal TieringPast Exercises Phase I (2001 - 2002) Fac/Sch tiered journals according to percentages External review conducted A total of 10,152 journals were assigned tiers 2 separate lists maintained – Faculty list and University Consolidated List – to deal with journals assigned different tiers by different Fac/Sch Phase II (2003 – 2005) Fac/Sch updated journals tiered Additions not to exceed 5% of the total number of journals tiered in Phase I No external review but replaced by a suitable report that included reasonable statistical calibration data A total of 10,439 journals were assigned tiers Phase III (2007 – 2008) Proposed new model consisting Super Tier, Tier 1 and Tier 2 Science and Medicine adopted Not adopted generally
Do we continue with Journal Tiering? No, not at the University level• Tiering still of value in some Schools/Faculties (e.g. super-tier)• Tier 1 numbers of journals should be decreased• Less reliance on tier 1 for evaluation• How should we deal with interdisciplinary research? BUT THEN SEE WHAT HAPPENED!
End of an ERA: journal rankings droppedJill Rowbotham , From: The Australian , May 30, 2011 5:51PMJOURNALS will no longer be assigned rankings in a radical shake up ofthe Excellence in Research for Australia initiative, announced byInnovation, Industry, Science and Research Minister Kim Carr today.JOURNALS will no longer be assigned rankings in a radical shake up ofthe Excellence in Research for Australia initiative, announced byInnovation, Industry, Science and Research Minister Kim Carr today.The ranking of journals as A*, A, B and C was the most contentiousaspect of the ERA exercise devised and administered by the AustralianResearch Council, with the first results published in January.“I wished to explore ways in which we could improve ERA so the aspectsof the exercise causing sector disquiet, especially issues around theranked journals list, could be minimised or even overcome,” Senator Carrsaid in a ministerial statement.
EVALUATING RESEARCH, The NATIONALRESEARCH FOUNDATION VIEW• High impact research (innovative, cutting edge, top-class local researchers, outstanding new recruits, and collaborators)• Building up manpower in Singapore (evaluation criterion for Deans and Heads at NUS)• Excellent execution (strong management team, good governance)• Potential economic benefits (including good procedures to “exploit” IP)Other measures• Quality of PhDs and post-docs trained• Integration of research, teaching and industrial development?
THE MILLION DOLLAR QUE$TION How to evaluate interdisciplinary research (IR) and correct misconceptions about - what is IR - the different types of IR - who should do IR
SINGAPORE IS A SMALL PLACE • International peer review of all major grants/programmes is pre-eminent but NOT SUFFICIENT • Benchmark against: Other Universities with similar constraints, e.g. UC Berkeley & UCSD (large teaching commitment) Other smaller countries that do very well in research e.g. Sweden, Switzerland, Israel But also develop the (unique?) NUS view Study failures as well as successes
Collaborations with Industry, NUS Enterprise 1. Education of NUS graduates as entrepreneurial leaders experiential education programs in entrepreneurship in Singapore and globally supporting NUS student and alumni initiatives & networks related to learning entrepreneurship 2. Facilitating the commercialization of NUS research Through a professionally-run industry liaison office services 3. Nurturing the creation of successful NUS spin-offs Through a professionally-run Incubator, seed-funding and mentoring system Through leveraging NUS alumni network in business and enterprise 4. Cooperation in graduate education
NUS Overseas CollegesExperiential entrepreneurship educationimmersing NUS students in leading entrepreneurial hubsaround the world• ONE year• Full-time interns in high-tech startup/innovative companies• Learn from the founders and entrepreneurs• Take courses at partner universities
NUS Overseas Colleges (2002) NUS College in Silicon Valley, USA Study at Stanford & work in the innovation “habitat” ≈ (2003) NUS College in Bio Valley, USA Study at UPenn & work in the US’ pharma hotbed ≈ (2004) NUS College in Shanghai, China Study at Fudan & work in China’s commercial hub ≈ (2005) NUS College in Stockholm, Europe Study at KTH/SSE & work in Europe’s No.1 IT hub ≈ (2008) NUS College in India – Experience India!Attend Entrepreneurship workshops and work in India’s high- tech hub ≈ (2008) iLEAD, Singapore Study in NUS & work in Singapore’s knowledge- intensive enterprises ≈ (2009) NUS College in Beijing, China Study at Tsinghua & work in China’s high-tech hub ≈ (2011) NUS College in Israel 6 months internship in Tel Aviv/Haifa
NUS AND INDUSTRY• Spawn new IP• Support and help grow exciting industry (Both “hard” and “soft”)• Consultancy• Attract high-level overseas industry to Singapore
Interdisciplinary Research,the Finance Cluster • Risk Management Institute • Institute of Real Estate Studies • School of Business • Asian Studies (e.g. demographics) • LKY School of Public Policy • Financial Mathematics • Applied Economics Prof HO Teck Hua • Saw Centre for Quantitative Finance Vice-President (Research Strategy)Professor Ho Teck Hua is in charge of overseeing and building the Universitys Finance and Risk Management integrative research cluster. Heconcurrently holds the Tan Chin Tuan Centennial Professorship. Prof Ho has been a consulting professor to the NUS Overseas College in SiliconValley since 2002.He received a B.S. with first-class honours in Electrical Engineering (1985) as well as an M.S. in Computer and Information Sciences (1989) from theNational University of Singapore. Additionally, from The Wharton School, University of Pennsylvania, he received an M.A. (1991) and a Ph.D. (1993)in Decision Sciences.Prof Ho is currently the William Halford Jr. Family Professor of Marketing, and the Chair of the Marketing Department at the Haas School of Businessat the University of California, Berkeley. Ho has been a chaired professor at U.C. Berkeleys Haas School of Business from 2002, and is also theDirector of the Asia Business Center at the Haas School of Business from October 2007. Ho earned his tenure at The Wharton School, University ofPennsylvania in 1999. He was Assistant Professor of Operations and Technology Management at the UCLA Anderson School of Management from1994-1997.
WHY INDUSTRIAL LABORATORIES /FACILITIES ON CAMPUS?• High level, innovative, cutting edge, high global reputation• Access to facilities• Joint participation in education (undergraduate/graduate)• Mutual benefit• Spin-offs from NUS graduates / alumni
NUS works closely with Industry for mutual benefit Clinical Imaging Research Centre (CIRC) • Partnership between NUS, A*STAR, and Siemens Medical Solutions • One of the first research sites in the world to use the Siemens’ MR-PET system • Application to clinical and cognitive problems Phase II: Planned Imaging Assets in 2011 • Research Cyclotron for Radio-labeling new and novel compounds • MRI-PET Soft Tissue Functional Imaging • PET-CT High Resolution Functional Imaging • SPECT CT Single Photon Imaging CIRC@CeLS Siemens MagnetomSlides courtesy of NUHS Trio 3 Tesla MRI
NUS works closely with Industry formutual benefitNUS-GE Singapore Water Technology CentreA unique Industry-University laboratory collaboration GE-NUS partnership contributes to GE Infrastructure Singapore as “global hydrohub” Water & Process Key Research Areas Technologies - Water Quality & Sensors - Sustainable Water Systems - Membrane Innovation - Water & Wastewater Reclamation Projects are carried out in collaboration with NUS Environmental Research Institute Analytical Services Laboratory at T-Lab provides cost effective and timely analyses
NUS works closely with Industry formutual benefitResearch and Development with Carl Zeiss SMT• A joint R&D Agreement was signed with Carl Zeiss SMT to advance the microscope facilities and research activities at NUSNNI in September 2009.• NUS first in Asia to house the Helium Ion Microscope• Novel advances made using the microscope will benefit the NUSNNI researchers, while new applications of the technique discovered by the e researchers will, in turn, enable Zeiss to further enhance the tool’s capactiy.
NUS works closely with Industry formutual benefit NERI-Agilent Environmental Research Alliance (NAERA)• The research alliance involves installing state of the art instrumentation for environmental research in the NERI laboratory• The alliance is expected to drive NERI’s environmental research programmes with access to new Agilent instrumentation• In collaboration with NERI, Agilent will showcase its instruments for a wide range of environmental applications, as well as develop new instrumentation and software for environmental applications
Conclusion• All research in NUS should be excellent, mediocrity wastes money and time, scarce resources in a small country.• We should have several peaks of excellence competitive for substantial external funding, in addition to quality research in a range of areas.• The mission of a global University is fundamental cutting edge research and excellent education of the next generation.• But never forget what the Customer wants!
Thank YOUQuestions & Answers MISSION To transform the way people think and do things through education, research and service