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IT Support Tools and Personalized Medicine Phyllis Teater, Chief Information Officer The Ohio State University Medical Center
Fundamental Objective of Informatics and Healthcare IT Delivering timely and contextually appropriate data, information, and knowledge in support of basic science, clinical and translational research, clinical care, and public health.
Computers are incredibly fast, accurate and stupid.Human beings are incredibly slow, inaccurate and brilliant.Together they are powerful beyond imagination. -Albert Einstein
Goal = Move Expert Knowledge and new Discoveries to the Point of Care
Historical trends in storage prices vs DNA sequencing costs “Next generation” sequencing technologies in the mid-2000s changed the trends and now threatens the conventional genome informatics ecosystem Notice: this is a logarithmic plot – exponential curves appear as straight lines. Lincoln D Stein Genome Biology 2010, 11:207
The Need for Data Integration and Analytics Data integration is a pervasive challenge faced in applications that need to query across multiple autonomous and heterogeneous data sources. Data integration is crucial in large enterprises that own a multitude of data sources, for progress in large-scale scientifc projects, where data sets are being produced independently by multiple researchers, … … Halevy A, Rajaraman A, Ordille J; “Data Integration: The Teenage Years. VLDB `06, September 1215, 2006, Seoul, Korea. Radiology Appl Icat ions Web Services Lab EMR Pathology IW
Information Warehouse Overview ADT Lab Respiratory Blood Endoscopy Cardiology Siemens Img Multi-Dimensional Analysis & Data Mining Real time Ad-hoc Query Meta Data CPOE OR system Patient Mgmt Dictated reports Pathology reports Daily Text Mining, NLP Patient Billing Practice Plans Weekly Pt Satisfaction Monthly Image Analysis Web Scorecards & Dashboards Cancer Genetics Wound Images Tissue Pulmonary Genomic Data De-Identification Honest Broker Web Research Benchmarking Error Report Information Warehouse User Access Acquisition Transfer DATAINTEGRATION Clinical Business Research External Wound Center
Constant Evolution in Technologies for Patients, Clinicians and Researchers 1950-60’s: Specialized computing facilities, programming languages, decision support, bibliographic databases, basic clinical documentation systems, first training programs Today: Tele-health, mobile computing, widespread EHR adoption, service-oriented architectures, genomic and personalized medicine applications, translational research