Abrahams intro panel
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  • 1. The Case for Personalized Medicine OSU Personalized Health Care Conference October 6, 2011 Columbus, Ohio Edward Abrahams, Ph.D. President Personalized Medicine Coalition
  • 2. The Case for Personalized Medicine
    • Shift emphasis in medicine from reaction to prevention
    • Enable the selection of optimal therapy and reduce trial-and-error prescribing
    • Make drugs safer by avoiding adverse drug reactions
    • Increase patient adherence with treatment
    • Improve quality of life
    • Revive drugs that failed in clinical trials or were withdrawn from the market
    • Help control the overall cost of health care
  • 3. Major Drugs Ineffective for Many Source: Spear B, Heath-Chiozzi M, Huff J Clinical Trends Molecular Medicine 2001; 7(5):201-4.
  • 4. Ineffective Therapies Waste Money
    • Major Drug
    • Hypertension Drugs
    • Ace Inhibitors
    • Heart Failure Drugs
    • Beta Blockers
    • Anti Depressants
    • SSRIs
    • Cholesterol Drugs
    • Statins
    • Asthma Drugs
    • Beta-2-agonists
    • Cost of Ineffectiveness to Healthcare System
    • $390 million – $1.2 billion
    • $345 million – $575 million
    • $2.3 billion – $5.8 billion
    • $3.8 billion – $8.8 billion
    • $560 million – $1.0 billion
  • 5. Personalized Medicine Coalition
    • The Personalized Medicine Coalition, representing scientists, patients, providers and payers, promotes the understanding and adoption of personalized medicine concepts, services and products to benefit patients and the health system.