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Lactose intolerance.
Lactose intolerance.
Lactose intolerance.
Lactose intolerance.
Lactose intolerance.
Lactose intolerance.
Lactose intolerance.
Lactose intolerance.
Lactose intolerance.
Lactose intolerance.
Lactose intolerance.
Lactose intolerance.
Lactose intolerance.
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Lactose intolerance.

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basic info about lactose intolerance

basic info about lactose intolerance

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  • 1. LACTOSE INTOLERANCE
  • 2. Lactose Lactose is a disaccharide of β-Dgalactose and β-D-glucose in β(1,4) linkage.  Human milk contains 200mmol/lit of lactose.  It is digested by enzyme lactase to form glucose and galactose in the brush border of the intestine. 
  • 3. Lactose containing food stuffs Fresh, skimmed , non fat and condensed milk.  Cream  Yoghurt  Cheese  Processed foods  Stuffings  Salad dressings etc. 
  • 4. Lactose intolerance Lactose intolerance, also called lactase deficiency or hypolactasia, is the inability to digest and metabolize lactose, a sugar found in milk.  Lactose intolerance is not an allergy because it is not an immune response but caused by lactase deficiency. 
  • 5. Lactose intolerance Lactose intolerance can occur in any age group or population.  However, people of African, Jewish, Hispanic, Asian, Middl e Eastern and Native American descent, Caucasians are at risk for developing lactose intolerance. 
  • 6. Symptoms Abdominal bloating and cramps  Flatulence  Diarrhoea  Nausea  Borborygmi (rumbling stomach)  Vomiting (particularly in adolescents). 
  • 7. Types of lactase deficiency Primary lactase deficiency is a genetically determined absence or decrease in the enzyme is noted.  Jejunal morphology is normal.  In non caucasian groups, primary lactase deficiency is abnormal in adulthood. 
  • 8. Secondary lactase deficiency Secondary, acquired, or transient lactase deficiency is due to the small intestinal mucosal disease, abnormalities of brush border cells and transport processes.  It is often associated with celiac sprue. 
  • 9. Congenital lactase deficiency Congenital lactase deficiency is a very rare, autosomal recessive genetic disorder that prevents lactase expression from the first feed.  Congenital lactose intolerance is serioue disorder in which the infants may fail to thrive unless given lactose free formula feed. 
  • 10. Diagnosis Dietary history of the patient who are complaining flatulance , abdominal pain , diarrhoea.  Familial history of the patient.  Check whether the patient has underwent partial gastrectomy and other related procedures.  Tests – stool acidity test, hydrogen breath tests. 
  • 11. Misdiagnosis Irritable bowel syndrome  Crohn's disease  Food poisoning  Gastroenteritis.  Celiac disease. 
  • 12. Management Avoiding lactose-containing products  Alternative products such as Plantbased milks and derivatives are inherently lactose free: soy milk, rice milk, almond milk, hazelnut milk, oat milk, hemp milk, peanut milk, horchata. 

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