Author(s): Gerald Abrams, M.D., 2009License: Unless otherwise noted, this material is made available under the termsof the...
Citation Key                          for more information see: http://open.umich.edu/wiki/CitationPolicyUse + Share + Ada...
M1 Patients and Populations: DISTURBANCES OF GROWTH       NEOPLASIA I                Gerald D. Abrams MDFall 2008
ORGANS/TISSUES SMALLER      THAN NORMAL•  DEVELOPMENTAL     AGENESIS     APLASIA     HYPOPLASIA     ATRESIA•  ACQUIRED    ...
UNILATERAL RENAL AGENESIS      Department of Pathology, University of Michigan
UNILATERAL RENAL   HYPOPLASIA Department of Pathology, University of Michigan
LIVER, BROWN ATROPHY G.D. Abrams, University of Michigan Medical School
ORGANS / TISSUES LARGER      THAN NORMAL•  HYPERTROPHY      INCREASE IN CELL SIZE•  HYPERPLASIA      INCREASE IN CELL NUMBER
HEART, NORMALDepartment of Pathology, University of Michigan
HEART, HYPERTROPHYDepartment of Pathology, University of Michigan
MYOCARDIUM, NORMALG.D. Abrams, University of Michigan Medical School
MYOCARDIUM, HYPERTROPHY G.D. Abrams, University of Michigan Medical School
SKIN, NORMALG.D. Abrams, University of Michigan Medical School
SKIN, HYPERPLASIAG.D. Abrams, University of Michigan Medical School
SKIN, HYPERKERATOSISG.D. Abrams, University of Michigan Medical School
MAMMARY GLANDG.D. Abrams, University of Michigan Medical School
MAMMARY GLAND, LACTATING  G.D. Abrams, University of Michigan Medical School
PROSTATE, HYPERPLASIA Source Undetermined
BREAST- FIBROCYSTIC     CHANGE  Source Undetermined
NORMAL BREASTG.D. Abrams, University of Michigan Medical School
BREAST               FIBROCYSTIC CHANGEG.D. Abrams, University of Michigan Medical School
ABNORMAL PATTERNS OF CELL GROWTH / DIFFERENTIATION•  METAPLASIA•  DYSPLASIA
ENDOCERVIX, SQUAMOUS     METAPLASIA G.D. Abrams, University of Michigan Medical School
ENDOCERVIX, SQUAMOUS     METAPLASIAG.D. Abrams, University of Michigan Medical School
SQUAMOUS EPITHELIUM,      NORMALG.D. Abrams, University of Michigan Medical School
SQUAMOUS EPITHELIUM, MODERATE DYSPLASIAG.D. Abrams, University of Michigan Medical School
SQUAMOUS EPITHELIUM,  SEVERE DYSPLASIAG.D. Abrams, University of Michigan Medical School
NEOPLASM / TUMOR•  MASS ( NEW GROWTH ) –   PROLIFERATING CELLS•  AUTONOMOUS•  NON-EQUILIBRIUM, UNCOORDINATED   GROWTH•  PE...
NEOPLASTIC       TRANSFORMATION•  SERIES OF GENETIC EVENTS•  CLONAL CHARACTERISTICS
Benign Tumor: growth by expansion        Malignant Tumor: growth by invasionRegents of The University of Michigan
BENIGN AND MALIGNANT         GROWTH•  BENIGN      COHESIVE /EXPANSILE      CIRCUMSCRIBED / LOCALIZED•  MALIGNANT      POOR...
UTERUS, LEIOMYOMA   Department of Pathology, University of Michigan
UTERUS, LEIOMYOMAG.D. Abrams, University of Michigan Medical School
BREAST CANCER  Department of Pathology, University of Michigan
COLON CANCERDepartment of Pathology, University of Michigan
COLON CANCERDepartment of Pathology, University of Michigan
CANCER INVADING COLONIC         WALL  G.D. Abrams, University of Michigan Medical School
METASTASIS•    A COMPLEX CASCADE OF EVENTS•    VIA BLOOD•    VIA LYMPH•    DIRECT
CANCER CELLS WITHIN BLOOD         VESSEL   G.D. Abrams, University of Michigan Medical School
CANCER CELLS WITHIN    LYMPHATIC G.D. Abrams, University of Michigan Medical School
PERITONEUM,           CARCINOMATOSISDepartment of Pathology, University of Michigan
PERITONEAL METASTASES Department of Pathology, University of Michigan
LIVER, METASTASESDepartment of Pathology, University of Michigan
EYE, PRIMARY MALIGNANT       MELANOMA Department of Pathology, University of Michigan
LUNG, METASTASES   Department of Pathology, University of Michigan
VERTEBRAE, METASTASES    Department of Pathology, University of Michigan
VERTEBRA, METASTASIS    Department of Pathology, University of Michigan
BRAIN, METASTASISDepartment of Pathology, University of Michigan
LIVER, METASTASESDepartment of Pathology, University of Michigan
Additional Source Information                                for more information see: http://open.umich.edu/wiki/Citation...
Upcoming SlideShare
Loading in …5
×

08.25.08: Neoplasia I

643 views
506 views

Published on

Slideshow is from the University of Michigan Medical School's M1 Patients and Populations: Medical Genetics Sequence.

View additional course materials on Open.Michigan:
openmi.ch/med-M1PatientsPopulations

Published in: Education
0 Comments
1 Like
Statistics
Notes
  • Be the first to comment

No Downloads
Views
Total views
643
On SlideShare
0
From Embeds
0
Number of Embeds
0
Actions
Shares
0
Downloads
9
Comments
0
Likes
1
Embeds 0
No embeds

No notes for slide

08.25.08: Neoplasia I

  1. 1. Author(s): Gerald Abrams, M.D., 2009License: Unless otherwise noted, this material is made available under the termsof the Creative Commons Attribution–Non-commercial–Share Alike 3.0License: http://creativecommons.org/licenses/by-nc-sa/3.0/We have reviewed this material in accordance with U.S. Copyright Law and have tried to maximize yourability to use, share, and adapt it. The citation key on the following slide provides information about how youmay share and adapt this material.Copyright holders of content included in this material should contact open.michigan@umich.edu with anyquestions, corrections, or clarification regarding the use of content.For more information about how to cite these materials visit http://open.umich.edu/education/about/terms-of-use.Any medical information in this material is intended to inform and educate and is not a tool for self-diagnosisor a replacement for medical evaluation, advice, diagnosis or treatment by a healthcare professional. Pleasespeak to your physician if you have questions about your medical condition.Viewer discretion is advised: Some medical content is graphic and may not be suitable for all viewers.
  2. 2. Citation Key for more information see: http://open.umich.edu/wiki/CitationPolicyUse + Share + Adapt { Content the copyright holder, author, or law permits you to use, share and adapt. } Public Domain – Government: Works that are produced by the U.S. Government. (USC 17 §105) Public Domain – Expired: Works that are no longer protected due to an expired copyright term. Public Domain – Self Dedicated: Works that a copyright holder has dedicated to the public domain. Creative Commons – Zero Waiver Creative Commons – Attribution License Creative Commons – Attribution Share Alike License Creative Commons – Attribution Noncommercial License Creative Commons – Attribution Noncommercial Share Alike License GNU – Free Documentation LicenseMake Your Own Assessment { Content Open.Michigan believes can be used, shared, and adapted because it is ineligible for copyright. } Public Domain – Ineligible: Works that are ineligible for copyright protection in the U.S. (USC 17 § 102(b)) *laws in your jurisdiction may differ { Content Open.Michigan has used under a Fair Use determination. } Fair Use: Use of works that is determined to be Fair consistent with the U.S. Copyright Act. (USC 17 § 107) *laws in your jurisdiction may differ Our determination DOES NOT mean that all uses of this 3rd-party content are Fair Uses and we DO NOT guarantee that your use of the content is Fair. To use this content you should do your own independent analysis to determine whether or not your use will be Fair.
  3. 3. M1 Patients and Populations: DISTURBANCES OF GROWTH NEOPLASIA I Gerald D. Abrams MDFall 2008
  4. 4. ORGANS/TISSUES SMALLER THAN NORMAL•  DEVELOPMENTAL AGENESIS APLASIA HYPOPLASIA ATRESIA•  ACQUIRED ATROPHY
  5. 5. UNILATERAL RENAL AGENESIS Department of Pathology, University of Michigan
  6. 6. UNILATERAL RENAL HYPOPLASIA Department of Pathology, University of Michigan
  7. 7. LIVER, BROWN ATROPHY G.D. Abrams, University of Michigan Medical School
  8. 8. ORGANS / TISSUES LARGER THAN NORMAL•  HYPERTROPHY INCREASE IN CELL SIZE•  HYPERPLASIA INCREASE IN CELL NUMBER
  9. 9. HEART, NORMALDepartment of Pathology, University of Michigan
  10. 10. HEART, HYPERTROPHYDepartment of Pathology, University of Michigan
  11. 11. MYOCARDIUM, NORMALG.D. Abrams, University of Michigan Medical School
  12. 12. MYOCARDIUM, HYPERTROPHY G.D. Abrams, University of Michigan Medical School
  13. 13. SKIN, NORMALG.D. Abrams, University of Michigan Medical School
  14. 14. SKIN, HYPERPLASIAG.D. Abrams, University of Michigan Medical School
  15. 15. SKIN, HYPERKERATOSISG.D. Abrams, University of Michigan Medical School
  16. 16. MAMMARY GLANDG.D. Abrams, University of Michigan Medical School
  17. 17. MAMMARY GLAND, LACTATING G.D. Abrams, University of Michigan Medical School
  18. 18. PROSTATE, HYPERPLASIA Source Undetermined
  19. 19. BREAST- FIBROCYSTIC CHANGE Source Undetermined
  20. 20. NORMAL BREASTG.D. Abrams, University of Michigan Medical School
  21. 21. BREAST FIBROCYSTIC CHANGEG.D. Abrams, University of Michigan Medical School
  22. 22. ABNORMAL PATTERNS OF CELL GROWTH / DIFFERENTIATION•  METAPLASIA•  DYSPLASIA
  23. 23. ENDOCERVIX, SQUAMOUS METAPLASIA G.D. Abrams, University of Michigan Medical School
  24. 24. ENDOCERVIX, SQUAMOUS METAPLASIAG.D. Abrams, University of Michigan Medical School
  25. 25. SQUAMOUS EPITHELIUM, NORMALG.D. Abrams, University of Michigan Medical School
  26. 26. SQUAMOUS EPITHELIUM, MODERATE DYSPLASIAG.D. Abrams, University of Michigan Medical School
  27. 27. SQUAMOUS EPITHELIUM, SEVERE DYSPLASIAG.D. Abrams, University of Michigan Medical School
  28. 28. NEOPLASM / TUMOR•  MASS ( NEW GROWTH ) – PROLIFERATING CELLS•  AUTONOMOUS•  NON-EQUILIBRIUM, UNCOORDINATED GROWTH•  PERSISTENT / IRREVERSIBLE
  29. 29. NEOPLASTIC TRANSFORMATION•  SERIES OF GENETIC EVENTS•  CLONAL CHARACTERISTICS
  30. 30. Benign Tumor: growth by expansion Malignant Tumor: growth by invasionRegents of The University of Michigan
  31. 31. BENIGN AND MALIGNANT GROWTH•  BENIGN COHESIVE /EXPANSILE CIRCUMSCRIBED / LOCALIZED•  MALIGNANT POORLY CIRCUMSCRIBED / INVASIVE….METASTASIZING
  32. 32. UTERUS, LEIOMYOMA Department of Pathology, University of Michigan
  33. 33. UTERUS, LEIOMYOMAG.D. Abrams, University of Michigan Medical School
  34. 34. BREAST CANCER Department of Pathology, University of Michigan
  35. 35. COLON CANCERDepartment of Pathology, University of Michigan
  36. 36. COLON CANCERDepartment of Pathology, University of Michigan
  37. 37. CANCER INVADING COLONIC WALL G.D. Abrams, University of Michigan Medical School
  38. 38. METASTASIS•  A COMPLEX CASCADE OF EVENTS•  VIA BLOOD•  VIA LYMPH•  DIRECT
  39. 39. CANCER CELLS WITHIN BLOOD VESSEL G.D. Abrams, University of Michigan Medical School
  40. 40. CANCER CELLS WITHIN LYMPHATIC G.D. Abrams, University of Michigan Medical School
  41. 41. PERITONEUM, CARCINOMATOSISDepartment of Pathology, University of Michigan
  42. 42. PERITONEAL METASTASES Department of Pathology, University of Michigan
  43. 43. LIVER, METASTASESDepartment of Pathology, University of Michigan
  44. 44. EYE, PRIMARY MALIGNANT MELANOMA Department of Pathology, University of Michigan
  45. 45. LUNG, METASTASES Department of Pathology, University of Michigan
  46. 46. VERTEBRAE, METASTASES Department of Pathology, University of Michigan
  47. 47. VERTEBRA, METASTASIS Department of Pathology, University of Michigan
  48. 48. BRAIN, METASTASISDepartment of Pathology, University of Michigan
  49. 49. LIVER, METASTASESDepartment of Pathology, University of Michigan
  50. 50. Additional Source Information for more information see: http://open.umich.edu/wiki/CitationPolicySlide 5: Department of Pathology, University of MichiganSlide 6: Department of Pathology, University of MichiganSlide 7: G.D. Abrams, University of Michigan Medical SchoolSlide 9: Department of Pathology, University of MichiganSlide 10: Department of Pathology, University of MichiganSlide 11: G.D. Abrams, University of Michigan Medical SchoolSlide 12: G.D. Abrams, University of Michigan Medical SchoolSlide 13: G.D. Abrams, University of Michigan Medical SchoolSlide 14: G.D. Abrams, University of Michigan Medical SchoolSlide 15: G.D. Abrams, University of Michigan Medical SchoolSlide 16: G.D. Abrams, University of Michigan Medical SchoolSlide 17: G.D. Abrams, University of Michigan Medical SchoolSlide 18: Source UndeterminedSlide 19: Source UndeterminedSlide 20: G.D. Abrams, University of Michigan Medical SchoolSlide 21: G.D. Abrams, University of Michigan Medical SchoolSlide 23: G.D. Abrams, University of Michigan Medical SchoolSlide 24: G.D. Abrams, University of Michigan Medical SchoolSlide 25: G.D. Abrams, University of Michigan Medical SchoolSlide 26: G.D. Abrams, University of Michigan Medical SchoolSlide 27: G.D. Abrams, University of Michigan Medical SchoolSlide 30: Regents of the University of MichiganSlide 32: Department of Pathology, University of MichiganSlide 33: G.D. Abrams, University of Michigan Medical SchoolSlide 34: Department of Pathology, University of MichiganSlide 35: Department of Pathology, University of MichiganSlide 36: Department of Pathology, University of MichiganSlide 37: G.D. Abrams, University of Michigan Medical SchoolSlide 39: G.D. Abrams, University of Michigan Medical SchoolSlide 40: G.D. Abrams, University of Michigan Medical SchoolSlide 41: Department of Pathology, University of MichiganSlide 42: Department of Pathology, University of MichiganSlide 43: Department of Pathology, University of MichiganSlide 44: Department of Pathology, University of MichiganSlide 45: Department of Pathology, University of MichiganSlide 46: Department of Pathology, University of MichiganSlide 47: Department of Pathology, University of MichiganSlide 48: Department of Pathology, University of MichiganSlide 49: Department of Pathology, University of Michigan

×