Author(s): Gerald Abrams, M.D., 2009License: Unless otherwise noted, this material is made available under the terms ofthe...
Citation Key                          for more information see: http://open.umich.edu/wiki/CitationPolicyUse + Share + Ada...
OUR MICROBIAL FRIENDS               The Digestive Tract                   Ecosystem                 Gerald D. AbramsWinter...
G.D. Abrams, University ofMichigan Medical School
Department of Pathology, University of Michigan
Department of Pathology, University of Michigan
G.D. Abrams, University of Michigan Medical School
G.D. Abrams, University of Michigan Medical School
G.D. Abrams, University of Michigan Medical School
G.D. Abrams, University of Michigan Medical School
G.D. Abrams, University of Michigan Medical School
G.D. Abrams, University of Michigan Medical School
G.D. Abrams, University of Michigan Medical School
G.D. Abrams, University of Michigan Medical School
G.D. Abrams, University of Michigan Medical School
G.D. Abrams, University of Michigan Medical School
G.D. Abrams, University of Michigan Medical School
G.D. Abrams, University of Michigan Medical School
Ilya MechnikovWikimedia Commons
DEFENSIVE FUNCTIONS OF THE     MICROBIAL FLORA•  PROVIDES “COLONIZATION RESISTANCE”•  STRENGTHENS MUCOSAL BARRIER•  STIMUL...
METABOLIC FUNCTIONS OF THE     MICROBIAL FLORA- ENZYMES PRODUCED- VITAMINS PRODUCED- SECRETIONS, FOODSTUFFS, DRUGS PROCESS...
G.D. Abrams, University of Michigan Medical School
G.D. Abrams, University of Michigan Medical School
G.D. Abrams, University of Michigan Medical School
G.D. Abrams, University of Michigan Medical School
G.D. Abrams, University of Michigan Medical School
G.D. Abrams, University of Michigan Medical School
G.D. Abrams, University of Michigan Medical School
G.D. Abrams, University of Michigan Medical School
G.D. Abrams, University of Michigan Medical School
Department of Pathology, University of Michigan
G.D. Abrams, University of Michigan Medical School
Department of Pathology, University of Michigan
PROBIOTIC•  A preparation containing live micro-   organisms that can enter the GI   ecosystem and produce positive health...
PROBIOTIC•  A preparation containing live micro-   organisms which, upon ingestion in   sufficient numbers, exert health b...
PREBIOTIC A substance or preparation whichstimulates the growth of a potentiallybeneficial micro-organism(probiotic)      ...
G.D. Abrams, University of Michigan Medical School
G.D. Abrams, University of Michigan Medical School
G.D. Abrams, University of Michigan Medical School
G.D. Abrams, University of Michigan Medical School
G.D. Abrams, University of Michigan Medical School
G.D. Abrams, University of Michigan Medical School
G.D. Abrams, University of Michigan Medical School
PROBIOTIC CAVEATS•    FEW CLINICALLY PROVEN EFFECTS•    STRAIN SELECTION PROBLEMATIC•    PREPARATION QUALITY VARIABLE•    ...
Additional Source Information                            for more information see: http://open.umich.edu/wiki/CitationPoli...
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01.16.09: The Digestive Tract Ecosystem

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01.16.09: The Digestive Tract Ecosystem

  1. 1. Author(s): Gerald Abrams, M.D., 2009License: Unless otherwise noted, this material is made available under the terms ofthe Creative Commons Attribution-Non-commercial-Share Alike 3.0 License:http://creativecommons.org/licenses/by-nc-sa/3.0/We have reviewed this material in accordance with U.S. Copyright Law and have tried to maximize yourability to use, share, and adapt it. The citation key on the following slide provides information about how youmay share and adapt this material.Copyright holders of content included in this material should contact open.michigan@umich.edu with anyquestions, corrections, or clarification regarding the use of content.For more information about how to cite these materials visit http://open.umich.edu/education/about/terms-of-use.Any medical information in this material is intended to inform and educate and is not a tool for self-diagnosisor a replacement for medical evaluation, advice, diagnosis or treatment by a healthcare professional. Pleasespeak to your physician if you have questions about your medical condition.Viewer discretion is advised: Some medical content is graphic and may not be suitable for all viewers.
  2. 2. Citation Key for more information see: http://open.umich.edu/wiki/CitationPolicyUse + Share + Adapt { Content the copyright holder, author, or law permits you to use, share and adapt. } Public Domain – Government: Works that are produced by the U.S. Government. (USC 17 § 105) Public Domain – Expired: Works that are no longer protected due to an expired copyright term. Public Domain – Self Dedicated: Works that a copyright holder has dedicated to the public domain. Creative Commons – Zero Waiver Creative Commons – Attribution License Creative Commons – Attribution Share Alike License Creative Commons – Attribution Noncommercial License Creative Commons – Attribution Noncommercial Share Alike License GNU – Free Documentation LicenseMake Your Own Assessment { Content Open.Michigan believes can be used, shared, and adapted because it is ineligible for copyright. } Public Domain – Ineligible: Works that are ineligible for copyright protection in the U.S. (USC 17 § 102(b)) *laws in your jurisdiction may differ { Content Open.Michigan has used under a Fair Use determination. } Fair Use: Use of works that is determined to be Fair consistent with the U.S. Copyright Act. (USC 17 § 107) *laws in your jurisdiction may differ Our determination DOES NOT mean that all uses of this 3rd-party content are Fair Uses and we DO NOT guarantee that your use of the content is Fair. To use this content you should do your own independent analysis to determine whether or not your use will be Fair.
  3. 3. OUR MICROBIAL FRIENDS The Digestive Tract Ecosystem Gerald D. AbramsWinter, 2009
  4. 4. G.D. Abrams, University ofMichigan Medical School
  5. 5. Department of Pathology, University of Michigan
  6. 6. Department of Pathology, University of Michigan
  7. 7. G.D. Abrams, University of Michigan Medical School
  8. 8. G.D. Abrams, University of Michigan Medical School
  9. 9. G.D. Abrams, University of Michigan Medical School
  10. 10. G.D. Abrams, University of Michigan Medical School
  11. 11. G.D. Abrams, University of Michigan Medical School
  12. 12. G.D. Abrams, University of Michigan Medical School
  13. 13. G.D. Abrams, University of Michigan Medical School
  14. 14. G.D. Abrams, University of Michigan Medical School
  15. 15. G.D. Abrams, University of Michigan Medical School
  16. 16. G.D. Abrams, University of Michigan Medical School
  17. 17. G.D. Abrams, University of Michigan Medical School
  18. 18. G.D. Abrams, University of Michigan Medical School
  19. 19. Ilya MechnikovWikimedia Commons
  20. 20. DEFENSIVE FUNCTIONS OF THE MICROBIAL FLORA•  PROVIDES “COLONIZATION RESISTANCE”•  STRENGTHENS MUCOSAL BARRIER•  STIMULATES IMMUNE SYSTEM
  21. 21. METABOLIC FUNCTIONS OF THE MICROBIAL FLORA- ENZYMES PRODUCED- VITAMINS PRODUCED- SECRETIONS, FOODSTUFFS, DRUGS PROCESSED- GI LINING CELLS NOURISHED
  22. 22. G.D. Abrams, University of Michigan Medical School
  23. 23. G.D. Abrams, University of Michigan Medical School
  24. 24. G.D. Abrams, University of Michigan Medical School
  25. 25. G.D. Abrams, University of Michigan Medical School
  26. 26. G.D. Abrams, University of Michigan Medical School
  27. 27. G.D. Abrams, University of Michigan Medical School
  28. 28. G.D. Abrams, University of Michigan Medical School
  29. 29. G.D. Abrams, University of Michigan Medical School
  30. 30. G.D. Abrams, University of Michigan Medical School
  31. 31. Department of Pathology, University of Michigan
  32. 32. G.D. Abrams, University of Michigan Medical School
  33. 33. Department of Pathology, University of Michigan
  34. 34. PROBIOTIC•  A preparation containing live micro- organisms that can enter the GI ecosystem and produce positive health effects.
  35. 35. PROBIOTIC•  A preparation containing live micro- organisms which, upon ingestion in sufficient numbers, exert health benefits beyond basic nutrition.
  36. 36. PREBIOTIC A substance or preparation whichstimulates the growth of a potentiallybeneficial micro-organism(probiotic) SYNBIOTICA mixture of probiotic and prebiotic.
  37. 37. G.D. Abrams, University of Michigan Medical School
  38. 38. G.D. Abrams, University of Michigan Medical School
  39. 39. G.D. Abrams, University of Michigan Medical School
  40. 40. G.D. Abrams, University of Michigan Medical School
  41. 41. G.D. Abrams, University of Michigan Medical School
  42. 42. G.D. Abrams, University of Michigan Medical School
  43. 43. G.D. Abrams, University of Michigan Medical School
  44. 44. PROBIOTIC CAVEATS•  FEW CLINICALLY PROVEN EFFECTS•  STRAIN SELECTION PROBLEMATIC•  PREPARATION QUALITY VARIABLE•  SAFETY ISSUES REMAIN
  45. 45. Additional Source Information for more information see: http://open.umich.edu/wiki/CitationPolicySlide 4: G.D. Abrams, University of Michigan Medical SchoolSlide 5: Department of Pathology, University of MichiganSlide 6: Department of Pathology, University of MichiganSlide 7: G.D. Abrams, University of Michigan Medical SchoolSlide 8: G.D. Abrams, University of Michigan Medical SchoolSlide 9: G.D. Abrams, University of Michigan Medical SchoolSlide 10: G.D. Abrams, University of Michigan Medical SchoolSlide 11: G.D. Abrams, University of Michigan Medical SchoolSlide 12: G.D. Abrams, University of Michigan Medical SchoolSlide 13: G.D. Abrams, University of Michigan Medical SchoolSlide 14: G.D. Abrams, University of Michigan Medical SchoolSlide 15: G.D. Abrams, University of Michigan Medical SchoolSlide 16: G.D. Abrams, University of Michigan Medical SchoolSlide 17: G.D. Abrams, University of Michigan Medical SchoolSlide 18: G.D. Abrams, University of Michigan Medical SchoolSlide 19: Wikimedia Commons, http://commons.wikimedia.org/wiki/File:Ilya_Mechnikov_(Nobel_1908).pngSlide 22: G.D. Abrams, University of Michigan Medical SchoolSlide 23: G.D. Abrams, University of Michigan Medical SchoolSlide 24: G.D. Abrams, University of Michigan Medical SchoolSlide 25: G.D. Abrams, University of Michigan Medical SchoolSlide 26: G.D. Abrams, University of Michigan Medical SchoolSlide 27: G.D. Abrams, University of Michigan Medical SchoolSlide 28: G.D. Abrams, University of Michigan Medical SchoolSlide 29: G.D. Abrams, University of Michigan Medical SchoolSlide 30: G.D. Abrams, University of Michigan Medical SchoolSlide 31: Department of Pathology, University of MichiganSlide 32: Department of Pathology, University of MichiganSlide 33: Department of Pathology, University of MichiganSlide 37: G.D. Abrams, University of Michigan Medical School , CC:BY-NC-SA, http://creativecommons.org/licenses/by-nc-sa/3.0/Slide 38: G.D. Abrams, University of Michigan Medical SchoolSlide 39: G.D. Abrams, University of Michigan Medical SchoolSlide 40: G.D. Abrams, University of Michigan Medical SchoolSlide 41: G.D. Abrams, University of Michigan Medical SchoolSlide 42: G.D. Abrams, University of Michigan Medical SchoolSlide 43: G.D. Abrams, University of Michigan Medical School
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