In 1963, scientists found that the initial
changes of Keratoconus were related to break
down of the corneas basement membrane
like conical shape.
They found that this cause happens due to
thin of cornea and its shape changes as a
From the above figure investigator conclude
that enzyme activity of Keratoconus increase
gradually compare to normal eye.
In this case cornea is responsible for 80% of
the absorption of ultraviolet B(UVB) light that
enters the eye.
Ultraviolet create free oxygen radicals, high
energy molecules, which if unchecked can
Keratoconus corneas produce enzyme which
is unique not found in normal corneas.
The main goal to focus on corneas which is
reduce something like cone which is different
from normal corneas.
Distance to reference point not curves.
Tangential:-Local or true curvature best of
Treatment is categories into two parts
conservative and surgical.
Now Surgical removing central nodular scars
by shaving the corneal surface may improve
contact lens and decrease the rate of
associated corneal abrations.
But conservative treatment take place without
any operation and intervention.
Placement of Intacs using manual dissection
technique appears to be efficacious treatment
modality for keratoconus.
Most patients achieve better spectacle
corrected visual acuity with concurrent
decrease in astigmatism.
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