DNA of the mice will go through mutation where BRCA1 and BRCA2 genes will be added to “X” sex chromosome.
Egg will be fertilized
The fertilized egg will be implanted in to a female mouse to go through a normal birth.
Over the life cycle of the mice the infected mice will be given periodic dosage of estrogen everyday at 24 hour interval will be given after birth to observed when normal cell growth turns into cancer growth.
As the estrogen level increases it will be easier to monitor when tumors arise.
Biopsy will be done every 24 hours to monitor cancer cell growth.