I do believe that the results suggest that Atenolol is an inferior choice for the initial treatment of HTN in the prevention of CV disease and new-onset diabetes compared to Amlodipine and I recommend that our patients switch to this drug today.
Prevention of cardiovascular events with an antihypertensive regimen of amlodipine adding perindopril as required versus atenolol adding bendroflumethiazide as required, in the Anglo-Scandinavian Cardiac Outcomes Trial-Blood Pressure Lowering Arm (ASCOT-BPLA): a multicentre randomised controlled trial.
Dahlöf B, et al. Lancet. 2005 Sep 10-16;366(9489):895-906.
The Anglo-Scandinavian Cardiac Outcomes Trial-- blood pressure lowering arm. (ASCOT)