Mukokutan kandidiasis


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Mukokutan kandidiasis

  1. 1. Noorahmah Adiany Ansari 110 207 005 Eko Wahyuddin S 110 208 063Counselor supervisor : dr. A.M.Adam, Sp.KK (K) Adviser : dr. Sari Handayani P. 1
  2. 2. Candidiasis is a fungal disease, which is acute or subacutecaused by Candida species usually by the species Candidaalbicans, and can affect the mucous membranes, skin, nails,GI tract, and can also infect the organ in systemic.The synonim of Candidiasis are Candidosis or Moniliasis 2
  3. 3. Candidiasis disease found worldwide, can affect all ages, both maleand female. Candidiasis also associated with predisposing factors Chronic Disease Contact with patients with sexually AGE transmitted diseases endogenous and Temperature and high pregnancy, obesity, Endokrinopati, exogenous humidity, Hygiene of skin predisposing factors 3
  4. 4. Candida albicans is the yeast in the oval size 2-6 × 3-9 μMthat can produce stem cells, pseudohyphae, and truehyphae. Figure 1. Candida in Pottasium hydroxide preparation. Pseudomycelia in clusters of grape-like yeast cells 4
  5. 5. Classification of Candidiasis infection based on thesite of predilection which is on mucocutan candidiasis,systemic candidiasis, cutis candidiasis, and chronicmucocutaneus candidiasis. 5
  6. 6. Based on an exposed spot, Conant et al (1971) share as a localcandidosis which can be distinguished clinically:Candidiasis of mucous membranes (mucocutaneous):1. Oral candidiasis (thrush)2. Perleche3. Vaginalis candidiasis (vulvovaginitis)4. Balanitis or balanopostitis5. Chronic mucocutaneous candidiasis 6
  7. 7. C.Albicans invasion decreased immunity into the tissue predisposing holding the patients factors body Tissuedamage Attachment of microorganisms in the host cell tissue supported by molecular enzymes of candida albicans Blastospora develop into C. albicans penetrate the mucosal epithelial hyphae and pseudo-hyphae cells apparent pressure from the tissue damage, so the invasion into the tissue can 7 occur.
  8. 8. Oral Candidiasis (Thrush). white looks gray pseudomembrane that covers the tongue, palate mole, inner cheek, and other oral cavity surfacesFigure 2. Oral candidiasis: thrush Extensive cottage cheeselike plaques, colonies ofCandida (pseudomembranous), Patches of erythema between the white plaquesrepresent erythematous (atrophic) candidiasis. 8
  9. 9. Perleche Lesions in the form of fissures or cracks in the skin atan angle of mouth; lesions underwent maceration, erosion,wet, and basically erythematous.Figure 3. Candida perleche with erythema and fissuring at the corners of the mouth. 9
  10. 10. Vulvovaginitis. white patches on erythematous mucosa erosive, ranging from thecervix to the introitus vagina, and especially the vagina 1/3 bottom. thelump apart from the mass of the vulva or vagina wall is composed ofnecrotic material, epithelial cells, and fungi.Figure 4. Vulvovaginal candidiasis. Figure 5. Vulvovaginal candidiasis.White patches appear on the White patches appear on theerythematous mucosa in the labia major erythematous mucosa in the cervixand minor 10
  11. 11. Balanitis or balanopostitiswhite patches on the membrane of the glans penis is oftenentirely become erythematous and erosiveFigure 6. candidiasis : balanoposthitis. Figure 7 .Erythema and white plaquesseveral discrete pustules on the glans seen on the glans penispenis and in the prepusium. and prepusium 11
  12. 12. Chronic mucocutaneous candidiasis. This disease arises because of the lack of leukocyte function orhormonal systems, usually found in patients with a variety of geneticdeficiency, generally found in children - children.Figure 7. Mucocutaneous candidiasis of the scalp of patients with chronic. 12
  13. 13. 1. Anamnesis and Physical Examination2. Direct examination. Mucocutaneous swabs examined with 10% KOH solution or by Gram staining : yeast cells, blastospora, or pseudo hyphae. Figure 8. Candida albicans: KOH preparation: Budding yeast forms and sausage-like form of pseudo hyphae 13
  14. 14. 2. Examination of cultures Material to be examined in order to be planted inSabouraud dextrose glucose, can also be affixed to theseantibiotics (chloramphenicol) to prevent bacterialgrowth. Figure 9. Colonies of Candida albicans. 14
  15. 15. 1. Oral Candidiasis (Thrush)Leukoplakia is a clinical termthat refers to an oral mucosalwhite patch that will not becontagious. Figure 10. Hairy leukoplakia appears as a broader and plaques on the lateral folds of the tongue 15
  16. 16. 2. Trichomonas vaginalisVulvovaginitis with vaginal secretionsThere is a yellow-greensecretions, smells bad andfrothy, vaginal walls are reddish, andthere are strawberry appereance of thecervix. Figure 11. This patient presented with a "strawberry cervix" due to a Trichomonas vaginalis infection, or trichomoniasis. The term "strawberry cervix" is used to describe the appearance of the cervix . The cervical mucosa reveals punctate hemorrhages along with accompanying vesicles or papules. 16
  17. 17. 2. Lichen Planuslichen planus occurs mainly onthe buccal mucosa, oftenbilateral, and sometimes on thetongue dorsal or lateral. Figure 12. Oral Lichen planus 17
  18. 18. 1. Avoid or eliminate the predisposing factors.2. Topical3. Systemic 18
  19. 19. Leukoplakia patients can be a squamous carcinoma,although rarely.Patients with AIDS oral candidiasis, chronicmucocutaneous candidiasis, can be an esophageal candidiasis.Candidiasis Vulvovaginalis or who have chronicCandidiasi Vulvovaginalis can lead to chronic dyspareunia todisrupt the marital relationship. 19
  20. 20. Prognosis of mucocutaneous candidiasis isgenerally good and depends on the severity ofthe predisposing factors. 20
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