Panzica & Viglietti's Lab
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Panzica & Viglietti's Lab

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Panzica & Viglietti's Lab Panzica & Viglietti's Lab Presentation Transcript

  • STEROID HORMONES AND NERVOUS SYSTEM: experimental studies to investigate the role of androgens and estrogens for the development of sexually dimorphic structures and behaviors within the central nervous system
  • WE WANT TO… …INVESTIGATE SOME NEUROPEPTIDES OR NEUROTRANSMITTERS SYSTEMS IN HIGHER VERTEBRATES: • vasopressin-vasotocin system • nitric oxide synthase system • endocrine disrupters- neural circuits- behavior http://psicologipsicologiaedintorni.files.wordpress.com/2009/03/lente_ingrandimento1.jpg
  • VASOPRESSIN-VASOTOCIN PARVOCELLULAR SYSTEM •Sexually dimorphic peptidergic system •Extremenly sensitive to gonadal hormones We are currently investigating the differentiation of this system in both mammals (rat, mouse) and birds (Japanese quail) View slide
  • NITRIC OXIDE SYNTHASE SYSTEM • control of sexual behavior • sexually dimorphic in rodens We are currently investigating the effects of estrous cycle on this system View slide
  • ENDOCRINE DISRUPTERS- NEURAL CIRCUITS AN BEHAVIOR We are currently investigating the alterations of investigative, social (in mice) and sexual (in mice and birds) behaviors and associated neural circuits following exposure to synthetic or natural endocrine disrupters