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 2010 ClinChem Annual Report
 2010 ClinChem Annual Report
 2010 ClinChem Annual Report
 2010 ClinChem Annual Report
 2010 ClinChem Annual Report
 2010 ClinChem Annual Report
 2010 ClinChem Annual Report
 2010 ClinChem Annual Report
 2010 ClinChem Annual Report
 2010 ClinChem Annual Report
 2010 ClinChem Annual Report
 2010 ClinChem Annual Report
 2010 ClinChem Annual Report
 2010 ClinChem Annual Report
 2010 ClinChem Annual Report
 2010 ClinChem Annual Report
 2010 ClinChem Annual Report
 2010 ClinChem Annual Report
 2010 ClinChem Annual Report
 2010 ClinChem Annual Report
 2010 ClinChem Annual Report
 2010 ClinChem Annual Report
 2010 ClinChem Annual Report
 2010 ClinChem Annual Report
 2010 ClinChem Annual Report
 2010 ClinChem Annual Report
 2010 ClinChem Annual Report
 2010 ClinChem Annual Report
 2010 ClinChem Annual Report
 2010 ClinChem Annual Report
 2010 ClinChem Annual Report
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2010 ClinChem Annual Report

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A due diligence Annual progress report for the CLINCHEM Department (www.clinchem.kasralainy.edy.eg) …

A due diligence Annual progress report for the CLINCHEM Department (www.clinchem.kasralainy.edy.eg)

An assessment tool for over all productivity and development of Education, Research and Laboratory healthcare services.

Highlights:
1- Mission, Vision and objectives
2- Role of the Department
3- HR
4- Organogram for the year
5- Lab Services
6- Scientific Research
7- Projects and more

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  • 1. ANNUAL PROGRESS REPORT Clinical & Chemical Pathology Department Reporting period: January 2010– December 2010 2010 Chair of the Department: Prof. Dr. Ahmed El-Saifi El Prepared by: Dr. Nelly Abulata Lecturer of Clinical Pathology 1
  • 2. Table of Contents I. Letter from the Chair……………………………………………………………………………………3 II. ClinChem at a glance 1 About us …………………………………….……………………………………………..…….….4 2 Role of the Department………….…………………..………………………………..……….…...5 III. Human Resources……………………………………………………………………………..………6 IV. Organizational Chart………………………………..………….……………………………………....7 1 Deputies……………………………………………………………………………………….…..…..7 2 Advisory Group….…………………..……………………………………………………………...…7 3 Seniors of Each Division…………………………………….……………………………….. ..……..7 4 Secretary General for the Council of the ClinChem Department & Technical Development Officer......7 5 Executive Team…………………………………………………………………………………….....8 6 Executive committees……………………………………………………………………………..…11 V. Laboratory Services we provide…………………………………………..……………………..….....12 1 Background Information…………………………………..……………………………….………......12 2 Total Annual Productivity…………………………………..…………………………………………13 3 Productivity per Lab……………………………………………………………………………….....15 4 Productivity per division……………………………….…………………………………….……..…19 5. Blood Bank Services…………………………………………………………………………….…....19 VI. 2010 Activities & Accomplishments……………………………………..……………………….…20 1. Scientific Research …………………………...…………………………..…………...……………...20 2. Quality Assurance Committee for Laboratory Services……………………………………………….23 3. Quality Assurance Committee for Education………………………………………………………...24 4. ClinChem Conferences……………………………………………………………………………….24 5. Postgraduate Library updated………………………………………………………………………..29 6. Department Website Redesigned and Updated………………………………………………………30 2
  • 3. I- LETTER FROM THE CHAIR: My goals for the department during 2010 were to rejuvenate and modernize it. Working together with more than 226 faculty members, nearly 30 residents and several hundred Technologists & Technicians, nurses, administrators, and staff who make up the department, we have made rapid strides toward achieving those goals. This year we achieved an overall annual productivity of 4,958,016 tests which could not have been reached without our dedicated manpower (944 employees). With the appointment of new Heads of Laboratories, Heads of Units and Laboratory Directors and with the creation of an Executive Committee, the Department now has the infrastructure it needs to continue its trajectory. All through 2010, we continued a steady expansion in our three major missions; Laboratory Services, Teaching & Training and Research Activities. In the Laboratory service arena, we continued to push ahead with the implementation of Quality Assurance System at Al– Manial Clinical Pathology Laboratory that has replaced our vulnerable home grown system. The construction of both the new Laboratory at the New Maternity Hospital & the New Emergency Hospital are among our top priorities and we anticipate moving into the facility by mid 2011. Teaching activities also remained very strong & the Department's pre– master & pre-doctorate training programs have been modified. In the Research arena, several research projects were funded by the faculty under the roof of the the 2-5yr plan for the Research activities of the Department which involved all 4 specialties of the Department (Hematology, Immunology, Microbiology and Chemistry. As for our international publications, over 20 articles were published by our faculty, several of which were in the high impact journals. Another source of pride for me and for the department as a whole was that the Department held 2 very successful Scientific Conferences; 1st Annual Scientific Conference “CLINCHEM 2010” nd from 31 March -2 April with the theme Molecular Biology into the Future & a 2 CLINCHEM 2010 th “Transfusion & Quality updates; Revolution not evolution” on the 24 of October. The Department is building on an extraordinary legacy and has great potential and we plan to make it a yearly event In summary, the Department is on the right path and we look forward to further progress. We hope that in collaboration with our colleagues in the Faculty and Hospital we can upgrade our research, teaching and clinical enterprise in a fashion that melds with the programmatic directions of the University as a whole. Prof. Ahmed El-Saifi Chair, Clinical and Chemical Pathology Department 3
  • 4. II- CLINCHEM AT A GLANCE: 1- ABOUT US Mission “Is to provide excellence in Laboratory services, Teaching, Training and Research activities”. Vision We aspire to be recognized as an Academic Department of excellence to support and enhance the mission and vision of Kasr Al-Ainy Faculty of Medicine, Cairo University. Objectives 1. To provide excellent laboratory medicine services for the patients of Kasr Al-Ainy Hospital in a timely & professional manner. 2. To provide an atmosphere of respect for our staff while encouraging continued personal growth, education and development. 3. To provide excellent teaching to a broad spectrum of health care professionals, health care workers and Lab personnel in conjunction with The University. 4. To provide the physical facilities and atmosphere where research activities can flourish, in collaboration with Kasr Al-Ainy Faculty of Medicine and other affiliated institutions. 5. To promote health, treatment and prevention of disease in the diverse population which we serve. 4
  • 5. 2- ROLE OF THE DEPARTMENT Laboratory Services Teaching & Research Training 1. Laboratory services: The Department offers Clinical and Chemical Laboratory services designed to meet the needs of physicians, & patients. The Department has 2 Main Labs at Al Al-Manial Hospital, a Lab. in each of the following Hospitals; the Specialized Hospital (4th Floor), the Internal Medicine Hospital, the Pediatric Japanese Hospital , the Pediatric Abou Elrish Hospital, King Fahd Hospital, the French Hospital in addition to Emergency Labs that ahd offer the Lab services during the evening and night shifts. The Department is also responsible for the Technical supervision of the Blood Bank. 2. Teaching & Training: The Department is committed to providing strong and balanced Teaching and Training nt programs mainly to Postgraduate students, principally in the Master and Doctorate degrees in Clinical and Chemical Pathology tailored to each student subspecialty Chemical (Hematology, Immunology, Microbiology or Chemical Pathology). The Department is Immunolog . also partly involved in the Teaching & Training of postgraduate students of other Departments enrolled in Master, Diplomas & Doctorate degrees in addition it provides instructional courses to the 6th year students. 6t 3. Research activities: The Research Faculty members within the Department are nationally recognized. The Research ranges from clinical to basic Research, with an emphasis on Hematologic Malignancies, Virology & Molecular Genetics. 5
  • 6. III. HUMAN RESOURCES The Department has a total manpower of around 944 employees. This comprises: · 287 Doctors ; 226 Faculty members, 36 Specialists & 27 Residents · 369 Technologists & Technicians · 59 Nurses · 131 Administration · 96 Cleaners Doctors 27 36 Faculty staff Specialists Residents 226 Human Resources 400 369 350 300 290 250 200 Doctors 131 150 96 100 59 Technologists & Technicians Nurses 50 Administration 0 Cleaners 6
  • 7. IV- ORGANIZATIONAL CHART The Organizational structure has been modified and effective teams have been built aiming to introduce the “we” culture and a more qualitative workplace. 1. Deputies: Chair of the Clinical & Chemical Pathology Dept Deputy for Scientific Research Affairs Team with representatives of all specialties Deputy for Teaching, Training Staff Positioning & relocation Affairs Team with representatives of all specialties Deputy for Examination Affairs Team with representatives of all specialties 1. A Deputy for Scientific Research Development Affairs: (Prof. Dr. Ali Shams ElDin) Who is in charge of the overall management for planning and coordinating multiple research teams and development activities and processes at a research and development unit/group level that will eventually lead to the international recognition of our Department that will in turn participate in the International recognition of the of Kasr Al Ainy Faculty of Medicine. This Deputy Al-Ainy together with a team of representatives of each specialty is responsible for the validation of all the resentatives MSc & MD protocols before they are officially registered. 2. A Deputy for Teaching, Training & staff relocation: (Prof. Dr. Azza Mostafa) Who is in charge of managing the teaching & training package that encompasses both these encom elements in order to maintain a motivated and skilled workforce and to fulfill the needs of the organization. This Deputy is also in charge of the relocation of staff to & from labs according to is the need. 3. A Deputy for Examination Affairs: (Prof. Dr. Safaa Al-Karaksy) A Who is in charge of managing and liaising with the heads of the units all the matters related to the examinations including schedules, exam development & examination boards formation. 7
  • 8. 2. Advisory Group The Advisors are composed and structured in order to provide non-binding but informative guidance to the Chair that serves as an ally during discussions when needed. The advisory group includes: · Prof. Dr. Omnia Yousef: Emeritus Prof. of Chemical Pathology · Prof. Dr. Souhair Helal: Emeritus Prof. of Clinical Pathology: subspecialty Microbiology · Prof. Dr. Naguib Zohair: Prof. of Clinical Pathology: subspecialty Hematology 3. Seniors of each Division The Department has 4 specialties and accordingly 4 seniors: · Prof. Dr. Safaa Al-Karaksy: Senior Immunologist · Prof. Dr. Tayssir Eyada: Senior Hematologist · Prof. Dr. Amani El-Kholy: Senior Microbiologist · Prof. Dr. Fatma El-Mougy: Senior Chemical Pathologist 4. Secretary General for the Council of the ClinChem Department & Technical Development Officer (Dr. Nelly Abulata) As the Secretary General of the Council she moderates the Council and several Departmental Committees. And as the Technical Development Officer she collaborates with Laboratory Managers, Heads of Laboratories, Heads of Units and other Project Managers in the restructuring of the organizational system, developing decentralization and defining job responsibilities within the Department aiming to ensure that the objectives and performance plans of the Department and Faculty were being met ; 5. Executive team Is composed of the Laboratory Directors (Administrative affairs), the Heads of Labs & Heads of Units (Technical Affairs) that direct, supervise and coordinate the functions and activities of the Hospital laboratories 8
  • 9. Main Lab at Manial Hospital Laboratory Head of Lab. (Technical) Lab Director (Administrative) Head of Hematology Unit Head of Immunology Unit Head of Genetics unit Head of the Molecular Unit Head of Microbiology Unit Manial Clinical Pathology Lab. Prof. Safa Al-Karaksy Prof. Dr. Mona Salah Prof. Dr. Nabil ElDanasoury Prof. Dr. Safaa AlKaraksy Prof. Dr. Hala Farawela Prof. Dr. Mona Salah A. Prof. Dr. Nada Nawar Laboratory Head of Lab. (Technical) Lab Director (Administrative) Head of Trace Elements Unit Head of Chemistry Routine Unit Head of Proteins Unit Manial Chemical Pathology Lab. Prof. Dr. Fatma ElMougy Prof. Dr. Badawy AlKhouly Prof. Dr. Badawy AlKhouly Prof. Dr. Lamia Mansour Prof. Dr. Sahar Abdel-Atty 9 Head of Hormones Unit Prof. Dr. Nadida Gohar
  • 10. Other Hospital based labs Laboratory Head of Lab. (Technical) Lab Director (Administrative) Head of Hematology Head of Immunology Head of Microbiology Head of Chemical Pathology Internal Medicine Hospital Lab. Japanese Hospital Lab. Prof. Dr. Laila Hegazy Dr. Magda Negm Prof. Dr. Laila Hegazy A .Prof Dr. Nancy ElGuindy Prof. Dr. Hanaa Arnaout TBD Prof. Dr. Hanaa Arnaout Dr. Safa Meshal Abou-Elrish Mounira Hospital Lab. Prof. Dr. Iman ElMahgoub Prof. Dr. Nesrine El-Gharabawy Prof. Dr. Nesrine ElGharabawy Specialized Hospital th Lab. (4 floor) French Hospital Lab. Prof. Dr. Tayseer Eyada Dr. Sheriene Abdel-Kader Prof. Dr. Tayseer Eyada Prof. Dr. Sheriene Mahmoud Prof. Dr. Souhair Helal Prof. Dr. Sahar Abdel Atty Prof. Dr. Azza Mostafa Dr. Hanan Ibrahim Prof. Dr. Naguib Zoheir Prof. Dr. Tagreed Gaafar Prof. Dr. Amani El Kholy Prof. Dr. Ola ElSissy King Fahd Hospital Lab. Psychiatric Hospital Lab. New ER Hospital Lab Maternity Hospital Lab. Sharm ElSheikh Int. Hosp. Prof. Dr. Hala Sheebah Blood Bank Prof. Dr. Mervat AlAnsary A. Prof. Dr. Hany Hussein A.Prof. Dr. Mona Mohie El-Din Prof. Dr. Maha Gaafar Prof. Dr. Amal Abdel Wahab Prof. Dr. Heba Sharaf ElDin Prof. Dr. Badawy Al-Khouly Prof. Dr. Badawy Al-Khouly A. Prof. Dr. Assistant Prof. TBD Iman Aya Nassef Mandour Assistant Prof. Mohamed Shehata Dr. Abeer Reehan 10 TBD A. Prof. Dr. Iman Mandour
  • 11. 6. Executive Committees 1. Executive Committee for Laboratory Affairs: As things evolved over time, we found that it was necessary to form an Executive Committee, which has been meeting every month for the past couple of months usually one week prior to the Board meeting of the Department. At those meetings, the Executive Committee reviews the major issues facing the Department, weighing pros and cons and making preliminary decisions, to be ratified by the Board as a whole at the actual Board meeting of the Department. The Committee is comprised of: 1. The Chair of the Department: Prof. Ahmed El-Saifi 2. The Head of the Laboratories · Prof. Azza Mostafa · Prof. Safaa Al-Karaksy · Prof. Mervat Al-Ansary · Prof. Tayssir Eyada · Prof. Fatma El-Mougy · Prof. Hanaa Arnaout · Prof. Laila Hegazy · Prof. Eman ElMahgoub · Prof. Hala Sheebah 3. The Laboratory Directors · Prof. Badawy Al-Kholy · Prof. Mona Salah · Prof. Nesrine ElGarabawy · Ass. Prof. Lobna ElMessery · Dr. Magda Negm · Dr. Abeer Reehan · Dr. Sherine Abdel-Kadr 4. Other members: · Prof. Sherief Naseh Amin (Deputy Head of the General Hospitals) · Prof. Amani Al-Kholy (Most Senior Microbiologist) · Prof. Omnia Youssef (Advisory Group member) · Prof. Souhair Helal (Advisory Group member) 2. Executive Committee for Blood Bank Affairs: Since the Department is responsible for the Technical supervision of the Blood Bank an Executive Committee for the Blood Bank has also been formed which will review and discuss any issues facing the Blood Bank. The Committee will start meeting on monthly basis starting from next month, typically one week prior to the Hospital Board meeting. The Committee is comprised of: 1. The Chair of the Department (Prof. Ahmed El-Saifi) 2. The Head of the Blood bank (Prof. Mervat Al-Ansary) 3. The Blood Bank Director (Dr. Abeer Reehan) 4. The Deputy Head of the General Hospitals (Prof. Sherief Naseh Amin) 5. Other members (to be determined). 11
  • 12. V- LABORATORY SERVICES WE PROVIDE 1. Background information: Our Laboratories provide an extensive menu of routine & specialized laboratory tests to the patients who seek care at Kasr Al-Ainy Hospitals. Lab Divisions · Hematology Laboratory · Clinical Immunology & Molecular Diagnostics · Clinical Microbiology · Clinical Chemistry 12
  • 13. 2. Annual Productivity: Hospital Lab Relevant Hospital Info Total Annual Inpatient beds Average Outpatients clinic cases per month Average ER cases per month Lab Productivity % out of the total annual Productivity of all labs Manial Labs 2,018 40,980 15,067 1804809 37% Japanese Lab 421 8700 4,876 553410 11% Abou El-Rish Lab 307 23,477 8,539 473044 10% Internal Medicine Lab. 357 2175 1,268 553298 11% 4th floor Lab 277 No Clinic 180 268033 6% King Fahd Lab 111 514 No ER 134430 3% French Lab Not available Not available 1070644 22% 1,200 13
  • 14. % out of the total annual productivity of 2010 6% 3% Manial 10% French 37% Internal Medicine Japanese 11% Abou ElRish 4th floor King Fahd 11% 22% 2010 Annual productivity 6000000 Total no. of tests & Doctors 4,958,016 5000000 4000000 3000000 2000000 1000000 (130) 1,804,809 (47) 1,070,644 (30) (21) (33) 553,410 553,298 473,044 0 Laboratory 14 (24) (2) 268,033 134,430 (10) 50,174
  • 15. 3. Productivity per Lab 1. Al-Manial Clinical & Chemical Pathology Labs: We have 2 labs at Al-Manial Hospitals one on the ground floor (Clinical Pathology) and one on the 2nd floor (Chemical Pathology) with a total no. of employees of 328. The Clinical Pathology Laboratory employs 169 people; 57 Faculty Staff (17 Emeritus Professors, 13 Professor, 2 Assistant Professors , 7 Lecturers, 6 Assistant Lecturer & 5 Demonstrators), 5 Specialists, 5 Residents, 14 Technologists, 47 Technicians, 6 Nurses, 20 Administration & 15 Cleaners. The Chemical Pathology Laboratory employs 159 people; 61 Faculty Staff (10 Emeritus Professors, 11 Professor, 8 Assistant Professors , 12 Lecturers, 17 Assistant Lecturer & 3 Demonstrators), , 3 Residents, 14 Technologists, 56 Technicians, 4 Administration & 16 Cleaners. Manial Labs 2000000 1800000 1600000 1400000 1200000 1000000 800000 600000 400000 200000 0 1804809 1381567 Hematology Immunology Microbiology 369530 Parasitology Chemical Pathology 37402 15571 739 15 Total
  • 16. 2. Japanese Lab: The Laboratory employs 83 people; 25 Faculty Staff (8 Professor, 6 Assistant Professors, 4 Lecturers & 7 Assistant Lecturer), 5 Residents, 1 Technologists, 39 Technicians, 13 Administration & 5 Cleaners. Japanese Lab 600000 500000 400000 300000 200000 100000 0 533410 393953 Hematology Immunology 120205 13665 Microbiology 13305 12283 Parasitology Chemical Pathology Total 3. Abou El-Rish Lab: The Laboratory employs 67 people; 18 Faculty Staff (5 Professor, 3 Assistant Professors , 6 Lecturers, 3 Assistant Lecturer & 1 Demonstrators), 10 Specialists, 5 Residents, 9 Technologists, 15 Technicians, 9 Administration, 2 Nurses & 6 Cleaner Abou ElRish ElMounira Lab 500000 450000 400000 350000 300000 250000 200000 150000 100000 50000 0 473044 320064 Hematology Immunology 103166 12594 21993 15227 Microbiology Parasitology Chemical Pathology Total 16
  • 17. 4. Internal Medicine Lab: The Laboratory employs 42 people; 14 Faculty Staff (3 Emeritus Professor, 3 Professor, 1 Assistant Professors , 3 Lecturers & 5 Assistant Lecturer), 2 Specialists, 5 Residents, 10 Technologists, 6 Technicians, 4 Administration & 2 Cleaners. Internal Medicine Lab 600000 500000 400000 300000 200000 100000 0 490319 553298 Hematology Immunology 55335 3220 1029 Microbiology 3125 Parasitology Chemical Pathology Total 5. 4th floor Lab: The Laboratory employs 53 people; 11 Faculty Staff (1 Emeritus Professors, 5 Professor , 2 Assistant Professors, 3 Lecturers), 3 Specialists, 10 Resident Specialists, 8 Technologists, 10 Technicians, 9 Administration, 4 Nurses & 6 Cleaners. 4th floor Lab 300000 250000 200000 150000 100000 50000 0 268033 216960 Hematology 40057 Immunology 4929 3660 3327 Microbiology Parasitology Chemical Pathology Total 17
  • 18. 6. King Fahd Lab: The Laboratory employs 21 people; 1 Faculty Staff (1 Professors), 1 Specialists, 7 Technologists, 5 Technicians, 5 Nurses, 1 Administrative Secretaries & 1 Cleaner. King Fahd Lab 160000 140000 120000 100000 80000 60000 40000 20000 0 134430 92325 Hematology 24692 Immunology 9837 2513 5055 Microbiology Parasitology Chemical Pathology Total 7. French Lab The Laboratory employs 223 people; 45 Faculty Staff (4 Emeritus Professor, 11 Professor, 11 Assistant Professors, 13 Lecturers, 4 Assistant Lecturer), 2 Senior Registrars, 17 Technologists, 73 Technicians, 7 Nurses, 56 Administration & 23 Cleaners French Lab 1800000 1600000 1400000 1200000 1000000 800000 600000 400000 200000 0 1714242 1480068 Hematology Immunology 159464 37317 18285 19108 Microbiology Parasitology Chemical Pathology Total 18
  • 19. 4. Productivity per division 16% 2% Hematology 1% Immunology Microbiology Chemical Pathology 81% 5. Blood Bank Services · Blood Bank Profile: The Blood Bank employees approximately 128 people who are involved in Blood Donation, Blood Processing and Hemapheresis. · Blood Bank Structure: • The Head of the Blood Bank: Prof. Dr. Mervat Al-Ansary • Administrative Director: Dr. Abeer Reehan. • The Team includes: 7 Specialists , 2 Residents, 6 Financial officers , 2 Administrative Officers, 2 Social Officers, 1 Statistician, 5 Technologists, 30 Technicians, 35 Nurses, 7 Administrative Secretaries, 11 Clerks, 22 Cleaners . 2010 Blood Bank services Total Outpatientclinic Donation campaign Total Rejected Screened HbsAg HCV HIV Syphilis Plasma Cryo 20099 218 19878 325 1098 31 57 14387 3523 30075 50174 917 1135 29140 49018 252 577 928 2026 49 80 65 122 25640 40027 -----3523 19
  • 20. VI- 2010 ACTIVITIES & ACCOMPLISHMENTS 1- Scientific Research · Project Profile: The aim of this project is to develop a plan for the Research activities of the Department over the coming 2-5 yrs which will involve all the specialties of the Department. The project will hopefully lead to the international recognition of the Department that will in turn participate in the International recognition of Kasr Al-Ainy Faculty of Medicine . Project starting date: 27/08/09 · Project structure: Project Leader: Prof. Ali Shams El-Din Project Team Members: Prof. Azza Mostafa, Prof. Taghrid Gaafar, Prof. Amani El-Kholy, Prof. Fatma El-Mougy, Prof. Mona Wasif, Prof. Hala Farawela, Prof. Afaf ElBannah, Prof. Iman Mansour, Prof. Hala Ali, Prof. Hala Gabr, Prof. Sahar Abdel Atty Ethical committee Members: Prof. Azza Mostafa, Prof. Dr. Safaa Al-Karaksy, Prof. Amani ElKholy, Prof. Fatma El-Mougy Key research subjects 1. HCV 2. Stem Cell Research 3. Neurodegenerative diseases 4. Infection prevention and control 5. Molecular basis of Hematological disorders 6. Juvenile Diabetes Mellitus. . Accomplishments to date: 1. Planning process: Done 2. Implementation: Done 3. Follow: in process . Research Grants: 1. STDF grant: "Stem Cell Therapy in Endstage liver cell failure". Principle investigator: Prof. Dr. Hala Gabr 2. Cairo University Grant: "Isolation and identification of Limbal Stem Cells". Co-investigator Prof. Dr. Hala Gabr . Research Awards: 1. A. Prof Heba Abdel Razik has won the Award “ ‫ةا و ا‬ ” 2. Prof. Dr.Hala Gabr won the “University Award for the High impact factor award” 3. Dr. Dina Ahmed Mehaney has been awarded “Best MD thesis in Cairo University” 20
  • 21. . Several projects received funding from the Faculty among which are: (>200,000LE) 1. Telomerase activity and hTERT mRNA expression in lymphoid leukemias (Shahira kamal, Sarah Adel) Fund value 38,900LE 2. Detection of IL18 and its m-RNA expression in idiopathic thrombocytopenic purpura (Iman Abdel Mohsen) Fund value 36,000 LE 3. Human brain and acute leukemia cytoplasmic (BAALC)gene andETS related genes (ERG) expression in acute myeloid leukemia (Amal Soliman Nasr) Fund value:14,400L.E 4. 6q aberrations in lymphoproliferative disorders (Dalia Gamil) Fund value:26,237LE 5. Expression of TSC1 and TSC2 gene in the newly diagnosed acute leukemia (Zeinab Ali) Fund value43.580 6. Study of the telomerase enzyme mutation in Acquired Aplastic Anemia in Egyptian children (Prof. Dr. Mervat Al-Ansary, Prof. Dr. Amal El-Beshlawy, Prof Dr.Mona El Tagui.Assistant, Prof. Dr. Mona Hamdy, Dr. Nelly Abulata, Dr. Fadwa Saeed) Fund value: 21,800 7. Genetic Polymorphism of Oxidative stress genes and the risk of non-Hodgkin’s Lymphoma and its relevance to HCV infections (Prof. Dr. Hala Farawela, Prof. Dr. Hamdy ElZawam, Prof. Dr. Somia Abdel Rahmna, A. Prof. Aya Nassef, A.Prof. Mervat Khorshied, A.Prof. Heba Gouda, Dr. Iman Shaheen, Dr. Nelly Abulata) Fund value 21, 790 LE 8. Prognostic relevance of pSTAT5 expression in acute myeloid Leukemia (A. Prof. Heba Hassan Abou Elewa) Fund value13,140 L.E. 9. Study of ex-vivo expanded bone marrow mesenchymal stem cells in aplastic anemia patients and the role of transcriptional factor gata-2 in fatty marrow replacement (A. Prof. Doha Abdel Hamid) Fund value 20,765 L.E. . International publications 1-Association Between The Monocyte Chemoattractant Protein-1 (MCP-1) 2518G/A Gene Polymorphism And Acute Myocardial Infarction Patients Among Egyptian Population. (El Mahgoub, Iman R; Afify, Reham A; Aal, Asmaa A Abdel; Beda, Dalia) . Coagulation Fibrinolysis J 2- Study of the Association of CYP2D6*4 Polymorphism with the Risk of Chronic Myeloid Leukemia (Sahar K Hussein, Asmaa A Abd El-Aal, Reham A. Aleem Afify) Journal of infection control. 3- AnnexinV and adhesion molecules expressions on erythrocytes in sickle cell anemia patients treated with hydroxyurea (Nermeen el Desoukey, Hend el Sherbiny, Dalia G. Amin) The Arab journal of laboratory medicine 4- Clinical relevance of angiopoietin-1, angiopoietin-2, and their receptor Tie-2expression in acute myeloid leukemia (Safaa M. El Karaksy . Nancy M. El Guindy . Heba M. Gouda . 21
  • 22. Mervat M. Khorshied . Iman A. Shaheen . Reham E. Abu Khalil . Noha Y. Ibrahim. Comparative Clinical Pathology 5-The clinical significance of methylenetetrahydrofolate reductase (MTHFR) polymorphisms in acute lymphoblastic leukemia (Hanaa H. Arnaout . Mervat M. Khorshied, Iman A. Shaheen . Heba M. Gouda . Noha Y. Ibrahim . Naglaa F. Koura.) . Comparative Clinical Pathology 6- Portal vein thrombosis and haematemesis in chronic liver disease. Are P-selectin and PSGL-1 clues? (Hoda A. Sadek , Bothina A. Madkour , Salwa M. Toima , Abeya F. Saleh , Iman A. Shaheen ,Rabab F. Yaseen, Emad El-Din A. Bayoumi) Arab Journal of Gastroentrology 7-The osteogenic differentiation potentials of umbilical cord blood haematopoietic stem cells. Mervat M. Khorshied ; Heba M. Gouda ; Iman A. Shaheen Tarek N. Al Bolkeny. Comparative Clinical Pathology. 8-Identification and clinical evaluation of the receptor for Hyal-uronic acid mediated motility (RHAMM/CD 168) in AML patients: Khorshied M., Omar D. Pan Arab Journal of Oncology 9- Nucleophosmin gene mutation in acute myeloid leukemia patients. Khorshied MM, Said WA, Shaaban HA. Saudi Med J 10- Autologous melanocyte–keratinocyte suspension in the treatment of vitiligo. BM ElZawahry, NS Zaki, DA Bassiouny, RM Sobhi, A Zaghloul, MM Khorshied and HM Gouda. JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY. 11- Detection of CXCL12 Gene Polymorphism and CXCR4 Expression in Egyptian Acute Myeloid Leukemia Patients (Aisha Abd El-Rahman, Samah Abdel-Hamid, Manal Makhlouf, Nermine El-Desouky, Mohamed Al-Feky and Sherif Yousri. The Journal of American Science 12-Detection of XRCC1 gene Polymorphisms in Egyptian Patients with Acute Myeloid Leukemia(Mona Salah El-Din, Hanan Raslan, Samah Abdel-Hamid, Manal Makhlouf) Comparative Clinical Pathology 13- Mesenchymal Stem Cell (MSC) Transfusion as a Novel Immunosuppressive Regimen with Possible Induction of Microchimerism. (Gamal Saadi, Mervat El-Ansary, Samah Abd ElHamid, Eman Abd EL-Aziz) Global Science of Books 4(2). 14- Dendritic Cell Vaccine as an Adjuvant Therapy in the Treatment of Chronic Myeloid Leukemia. Mervat El-Ansary, Mervat Mattar, Shereen Kamel, Samah Abd El-Hamid, Rania Abou Elnour Global Science of Books 4(2 15- Phase I Trial: Mesenchymal Stem Cells Transplantation in End Stage Liver Disease.M El-Ansary, Sh Mogawer, I Abdel-Aziz, S Abdel-Hamid. Journal of American Science. 6(12):135144 16- Cytogenetic study of the effect of Schistosoma mansoni infection on human peripheral blood lymphocytes and the role of B-carotene and vitamin E in modulating this effect .Mervat El Ansary, Iman Khaled, Abeya Fouad, Ola Mahmoud, Emad Baioumi, Heba Abo Bakr. Journal of American Science. 22
  • 23. 17- Celiac Disease in Children and Adolescents with Autoimmune Hepatitis : a Single – centre Experience .Mortada El-shabrawi ,Hanna El-Karasy,Nabil Mohsen ,Mona Isa ,Mohammed Al-Biltagi , Mervat El-Ansari . Journal of Tropical Pediatrics Advance Access 18- Flow cytometric detection of leukemic stem cells (LSCs) in Egyptian pediatric B-acute lymphoblastic leukemia (Manal W. El-Masry & Mervat M. Khorshied & Iman A. Shaheen & Nelly N. Abulata & Tarek A. Hashem) Comparative Clinical Pathology 19- Case Control Series of Intrathecal Autologous Bone Marrow Mesenchymal Stem Cell Therapy for Chronic Spinal Cord Injury. Nirmeen A. Kishk, Hala Gabr, Sherif Hamdy,Lamia Afifi , Noha Abokresha, Hayam Mahmoud,Ahmed Wafaie, and Dalia Bilal. Neurorehabil Neural Repair July 26, 2010. DOI: 10.1177/1545968310369801 20- Feasibility, Safety, and Efficacy of Directly Transplanting Autologous Adult Bone Marrow Stem Cells in Patients With Chronic Traumatic Dorsal Cord Injury. A Pilot Clinical Study. Osama S. Abdelaziz, Ahmed Marie, Mohamed Abbas, Mohamed Ibrahim, and Hala Gabr. Neurosurg Q 2010;20:216–226. 21- Autologous Mesenchymal Stem Cells for Neuro-Regeneration After Traumatic Spinal Cord Injury: A Comparison Between Bone Marrow and Peripheral Blood Populations. Abo ElKheir W, Gabr H, Awad MR, von Wild K, and Ramadan M. American Journal of Neuroprotection and Neuroregeneration Vol. 2, 1–8, 2010 IF: 6.2 & received the University Award for the High impact factor award 2- Quality Assurance for Laboratory service . Project profile: The aim of Quality assurance project (QA) is to ensure that the Laboratories of Cairo University Hospitals provide services that meet the best quality standards. . Project starting date: 27/08/09 . Project Structure: Project Leader: Dr. Ola Khashaba Project Team Leaders (2009/2010) : Prof. Safaa Al-Karaksy (Immunology), Prof. Naguib Zoheir (Hematology), Prof. Mona Wasif (Microbiology),Prof. Lamiaa Mansour (Chemical Pathology) Project Team Members: Relevant staff members in each team. . Accomplishments during 2009/ 2010 at Main Laboratories (Al-Manial Clinical Pathology Lab., N.B. Chemical Pathology Lab. joined the project late by mid -year 2010) 1. Initial assessment & Gap analysis in Al-Manial Lab using prepared checklists: Generic & specific 23
  • 24. 2. Team building 3. Awareness & Training sessions: For doctors and technicians 4. Development of standardized forms to be used in all departments including: Q.C, Calibration, Maintenance, Temperature control, Refrigerator content and maintenance card; in addition to special forms for some procedures e.g. ELISA, manual procedures, and Cytochemistry. 5. Implementation of the developed forms in all relevant previously mentioned departments with varying degree of compliance according to the results of the internal audits performed by the project leader and the submitted audit reports. 6. Two formal announced internal audits were performed one on March 2010 and the second on June 2010 (which included the Chemical Pathology lab.).Additional random audits were performed through informal communication with the process owners as one way of improving their performance. 7. Work is in progress to fully implement the Intranet through which the quality control will be automated. 8. Work is in progress to teach doctors in charge of developing and interpreting the control charts (or just how to read them after automation) and using the Westgard rules. 9. Training sessions and meeting with the new teams were regained by the end of the year 2010. 3- Quality Assurance for Education · Project Profile: The aim of this project is to check how well the Department meets it’s responsibilities, identifies good practice and makes recommendations for improvement. . Project starting date: 1/10/10 · Project structure: Project Leader: Prof. Hala Sheebah Project Coordinator: A. Prof Mervat Khorshied Project Team Members: Prof. Hala Ali, Prof. Nehad Mosaad, A.Prof. Maha Gaafar, A.Prof. Aya Nassef, A. Prof Mervat Khorshied, Dr. Safa Meshaal, Dr. Rania Darwish, Dr. Safaa ElGabarty . Accomplishments to date: 1. 2. 3. 4. 5. 6. Authentification of all the committees within the department Gathering available & preparing unavailable job description for all the types of jobs & roles Following up on the efficiency of teaching & training via evaluation surveys. Maintaining the system & following up on complaints Listing of the no. registered master & doctorate thesis’s Listing of the no. of the number of projects that have received funding from the faculty. 24
  • 25. 4- Training courses/ workshops: • Training course for “Screening metabolic disorders by Tandem Mass Spectrometry” Organized via a collaboration between the Chemical Pathology team (Prof. Dr. Fayza A Hassan Prof. Dr. Fatma El-Mougy Prof. Dr. Sahar Abdel-Atty Prof. Dr. Iman Mandour A. Prof.Dr. Marian Morgan Dr. Dina Mehaney Dr. Mohammed A. Monem) and the Pediatric Endocrinology team at Pediatric Hospital • Workshop in collaboration with ESPCR lead by Prof. Dr. Hala Gabr on: " Isolation, characterization and tagging of Adipose-derived stem cells“ • 2 workshops Lead Prof. Amani Al-Kholy & her Team ( A.Prof. Mervat Gaber Al-Anainy, A.Prof. Mona Mohieddin Abdel Halim, Dr. Mariam Adel, A. Lecturer Mai Sherief) in collaboration with NAMRU-3 & USA-CDC: 1. Survey of antimicrobial consumption in Cairo Univ Hospitals 2. Use of PDA in Clinical surveillance for healthcare associated infections in ICUs • Workshop on “Molecular Diagnosis of Acute Respiratory infections”; lead by Prof. Amani AlKholy, Prof. Mona Salah, A. Prof. Iman AbdelRahman in collaboration with NAMRU-3 4- ClinChem Conferences The Department held 2 very successful Scientific Conferences; the 1st CLINCHEM 2010 Conference" Molecular Biology: Into the future" held from 31st of March -2nd of April at CICC had a record-breaking attendance of nearly 600 participants in the could not have been achieved without the support of sponsors like SIEMENS,EL-DAWLEYA,TECHNOSCIEN, CLINILAB,ETICO,ENDOMEDIX&ULTRADIAGNOSTICS. In response to the feedback we received from our attendees and sponsors we decided to launch the 2nd CLINCHEM 2010 Conference "Transfusion Medicine & Quality updates: Revolution not evolution" that was held on the 24th of October, 2010 at the Learning Resources center at Kasr Al-Ainy Faculty of Medicine, Cairo University which was another great success thanks to sponsors such as DIA MED, FUTURE HORIZON, SPECTRA, SIEMENS & INTERPHARM. Our goals for the Conferences were simple, but bold: to bring together successful Laboratory Medicine professionals, Clinicians, Scientific and Medical publishers and Biotechnology companies, to discuss opportunities and challenges in the exciting field of Genetics & Tissue Engineering, by doing so, share the most up-to-date strategies explore recent developments and identify fruitful avenues for further research to enhance the Quality of our Healthcare Services. 25
  • 26. 1st ClinChem Conference 2010 “Molecular Biology: Into the future": 31st of March -2nd of April at Cairo International Conference Center General info Conference President Prof. Ahmed El-Saifi Vice President Prof. Azza Mostafa Secretary General Prof. Fatma El-Mougy Dr. Nelly Abulata Conference Coordinator · Organizing Committee A. Prof. Mervat Gaber A. Prof. Noha Shaheen Dr. Mervat Khorshied Dr. Nelly Abulata Dr. Heba El-Baz Dr. Riham El-Sayed Prof. Omnia Youssef Prof. Safaa Al-Karaksy Prof. Amani Al-Kholy Prof. Hala Farawela Prof. Mona Salah Prof. Sahar Abdel Atty Scientific Program Committee Hematology Committee Prof. Ali Shams ElDin Prof. Azza Ahmed Prof. Naela Omran Prof. Tayssir Eyada Prof. Hanaa Arnaout Microbiology Committee Prof. Walaa Gad Prof. Souhair Helal Prof. Amani Al-Kholy Prof. Mona Wassif Prof. Nevine El-Rasheedy . Immunology Committee Prof. Nawal Affifi Prof. Nehad El-Sheemy Prof. Safaa Al-Karaksy Prof. Taghrid Gaafar Prof. Mervat Al-Ansary Chemistry Committee Prof. Omar Al-Roubi Prof. Omnia Youssef Prof. Mona Salem Prof. Fayza Abdel Hamid Prof. Nadida Gohar 26
  • 27. ENTRANCE TO THE HALL PANEL AUDIENCE 27
  • 28. 2nd ClinChem Conference 2010 "Transfusion Medicine & Quality updates: Revolution not evolution" that was held on the 24th of October, 2010 at the Learning Resources center at Kasr Al-Ainy Faculty of Medicine General info Prof. Dr. Ahmed El-Saifi Conference President Prof. Dr. Mervat Al-Ansary Conference Vice President Dr. Nelly Abulata Conference Coordinator Organizing Committee Prof. Dr. Hala Gabr A. Prof. Nermeen El-Dessouky Dr. Rania Zayed Dr. Heba El-Baz Dr. Heidi Goubran Scientific Program Committee Prof. Dr. Nawal Afifi Prof. Dr. Azza Mostafa Prof. Dr. Safa Al-Karaksy Prof. Dr. Mervat Al-Ansary Prof. Dr. Azza Abou El-Enain Prof. Dr. Amaal El-Beshlawy Prof. Dr. Mervat Mattar Prof. Dr. Fikri Goubran Prof. Dr. Faten Moftah Prof. Dr. Magdy El-Ekiaby 28
  • 29. ENTRANCE TO HALL AUDIENCE NETWORKING 29
  • 30. 5- Postgraduate Library The Department upgraded its postgraduate library books with the latest books in Hematology, Immunology, Microbiology, Genetics, Chemistry in addition to a range of books concerned with eLearning, Presentation skills, Research methodology & Quality Assurance. The new books include: Hematology 1. Hemato-pathology atlas (2009) 2. Clinical Laboratory Haematology(2009) 3. Haematology Clinical cases :Q&A (2009) Transfusion Medicine 1. Transfusion Medicine & haemostasis(2009) 2. Practical Transfusion Medicine (2009) Immunology 1. Cellular & Molecular Immunology (2010) 2. Cell biology & genetics (2008) 3. Q&A in Immunology & Microbiology(2010) Microbiology 1. Microbiology (2010) 2. Medical Mycology (2009) 3. Case files in Microbiology (2009) 4. Q&A in Immunology & Microbiology(2010) New era books Chemistry 1. Clinical Chemistry (2010) 2. Clinical Chemistry (2010) 3. Clinical Biochemistry Metabolic and clinical aspects (2008) 4. Endocrine & Diabetes Clinical cases: Q&A (2009) 5. Q&A in Biochemistry (2010) 6. Drug assay (2010) Molecular 1. Genetics: Analysis& Principles(2008) 2. Advanced Genetic analysis (2009) Miscellaneous 1. Manual of Laboratory diagnostics (2008) 2. Phlebotomy (2009) 1. Management (2008) 2. Medical Ethics (2010) 3. Medical Quality management (2008) Educational books (new) 1. Curriculum Leadership (2010) 2. Challenging e-learning in the University (2009) 3. Educational Research in Higher Education (2010) 4. Learning and Teaching in Higher Education (2009) 5. Presentation skills the Complete Handbook (2008) 30
  • 31. 6- Website redesign & updating: The website for the Clinical & Chemical Pathology Department has been redesigned, expanded, updated, and published on the internet at: http://www.clinchemcairo.org Home About us Laboratory Services Projects Teaching &Training Faculty Events Contact us Please contact us for additional information about our Department. Prof. Dr. Ahmed El-Saifi, Saifi, MD Chair, Department of Clinical and Chemical Pathology Contact the Chair's Office 2010 Annual Progress Report 2009 Annual Progress Report 31

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