1. METAOME SCIENCE INFORMATICS
Democratizing big data in the Life Sciences and Health Care
Dr. Prajwal Bhat
2. THE PROBLEM
How can a doctor select the best
Cancer therapy for a patient based
on his genetic profile?
CLINICAL DECISION SUPPORT
Can this drug be used to treat other
The underlying cause in both scenarios is the same!!
3. Data is siloed – scattered across various sources
Data access is not easy
Analytical tools are too complex – require informatics skills
Biologists are not computer scientists!
“Life Science researchers hit a wall when it comes to analyzing
and gathering insights from their data”
4. OUR SOLUTION
A radical solution - intelligent and domain-aware
A vast Knowledge Graph mapping every known biological entity and
>1 Billion connections, and growing
5. OUR SOLUTION
Data is more accessible
Always know what is relevant
Point and click analytics on the Knowledge Graph
6. OUR SOLUTION
• Understand how data relates to
• Explore causal connections
• Overview from a systems level
• What are the likely side-eﬀects?
• Is there a better combination of
• What is the best treatment for a
patient with a given genetic
7. MARKET SIZE
Million potential users
$20 subscription per month à $1 Billion
5% market share à
Health Care segment is at least 10x
8. BUSINESS MODEL
- Direct to the end-user
No more cumbersome enterprise installations!
Subscription - $20/user/month
Individual, Group or Enterprise subscriptions
Kalpana Krishnswami, CEO
Kalpana has over 2 decades of experience in developing, managing and bringing new products to the market. She has
previously founded Jigyasa – an NSF funded eLearning company, Instantiations – now acquired by Google. Kalpana has
an integrated MS from IIT, Delhi and an MS in Computational Chemistry from Wright State University. She has previously
worked at UNC Supercomputing Center, GE, CambridgeSoft and Jubilant Biosys
Ramkumar Nandakumar, CTO
Ram's background is in bioinformatics, data mining and knowledge management. Ram brings over 20 years of rich and
diverse experience with biological databases and expertise in managing commercial bioinformatics products (Monsanto,
Max Planck Institute, University of Cambridge and Jubilant Biosys). Ram has an MS and a specialization in bioinformatics
from Madurai Kamaraj University.
Dr. Prajwal Bhat, Product Manager
Prajwal has 8 years of experience in Computational Biology. His work largely focused on applying graph-theoretic
methods to solve problems in Biology. Prajwal has worked extensively on problems such as protein function prediction
and gene functional analyses. Prajwal has a PhD in Computational Biology from University of London, UK.
Advisors & Investors
NSRCEL – IIM, Bangalore