Nanotechnology in surgery

Nanotechnology in Surgery
Louizos Alexander Louizos
ΜSc Nanotechnology & Nanosciences
PhD candidate in Nanomechanics
Resident in Vascular Surgery

What is NanoTech ?
Tech for objects in the size scale of < 100 nm
Nanomedicine Nanotechnology in Medicine

“Nature is our playground through a holistic synthetic approach to science”.
Biological Material, DNA synthesis
MechanicalProperties
NOVEL MATERIALS THROUGH NOVEL APPROACH TO SCIENCE
Chemistry & SurfaceScience
Optical Properties
Electronic Properties
Electron Microscopy, AFM

Who is the oldest Nanotechnologist?

Mother Nature has had 4.5 billion years to play with inorganic matter and build nanomachines that prove the feasibility of nanotechnology in medicine
FACT THAT LED TO BIOMIMETIC TECHNOLOGY

Surgery
Surgeons operate in the macro scale.
We promote the self healing of the body so we do not heal. The reason for the tissue malfunction is on molecular basis
All surgeons (almost all ) know that the more gentle you are with the tissue the less the complications
We need lessons from nature on how to heal
gently and elegantly from the bottom up!

Trends in surgery
We created better tools to assist our hands
We begun to be less invasive: Laparoscopic tools , endovascular treatments
We created robotic hands that are performing better than human hand: Da Vinci Robotic Surgery
We are now experimenting with microrobots ( I will show you some of them)
We will finally move to the nanorobotics technology
SEEMS BIT FRUSTRATING
FOR YOUR TRAINING AS A SURGEON 
The only thing that saves us is the time lag between
experimental phase, clinical trials and widespread use of methods

Robots in Surgery
Da Vinci Robotic Surgery
Mag-μbot
Endoscopy Capsule
Mag-μRobot (Carnegie Mellon )

Nanorobots
When and how?
In about 10-20 years but we do not know how they will be like.
We presume them to be like natural nanomechines (e.g. mitochondria)

Lab On A Chip
No need for an angry (why did you awake me up in the middle of the night) microbiologist.
Multiple exams on a small scale machine
Minimal invasive: less blood for the same exams
Can be preventive in nature – Self assessment by patients

Nanoparticle Assisted Surgery
Targeted nanoparticles to specific tumors will provide visual guide for the right tissue removal (not too much, not too little).
No need for histological tissue exam of the extremities of the oncectomy.

The Ideal Grafts
Enhanced Biocompatibility through Biomimetism of nanotopography (still needing surgery for transplantation, hint: Future surgical specialties will be boosted toward transplantation of every possible human part)
Artificial Grafts are mistaken for Real Tissue if they look like tissue
We should still embed “if they function like tissue”
Future of Grafts 3D Printing and Stem Cells
The future may be towards “transcendence” meaning hacking of our physiological evolutionary path towards an enhanced man – machine hybrid. (possibly in the next 50 years)

Tissue Engineering - Bioprinting
Bioprintingcan be defined as computer-aided, automatic, layer-by-layer deposition, transfer, and patterning of biologically relevant materials.

Potential Dangers of Nanomedicine
D.I.Y. Bio: Biotechnology tools on the hands of ordinary people through the miniturization of devices
Nanoparticles not yet deeply studied in terms of toxicity and safety
Great Goo-> uncontrolled self replicating nanorobots

Love Nano? Help me Spread the word
Join me in my blog at http://www.nanotechgalaxy.com , I need help in writing articles.
Send me en email at alouisos@gmail.com
Join Nanotechnology facebook team at http://on.fb.me/FaceBookNano
Follow me on twitter at http://twitter.com/louizos

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Nanotechnology in surgery

by Louizos Louizos on Jan 30, 2011

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