0
Pathophysiology Yu-Hong Jia, Ph.D Department of pathophysiology Dalian medical university
Introduction <ul><li>Concept </li></ul><ul><li>Goal </li></ul><ul><li>Status </li></ul><ul><li>Contents </li></ul>
Ⅰ. Concept <ul><li>Pathophysiology is a subject to explore the rule and mechanism of the origin and evolution of disease. ...
Ⅱ. Goal, status, contents <ul><li>Explore the general rule and mechanism of occurrence and development of disease </li></u...
investigation <ul><li>Question 1: Which basal subjects do you think are most useful for clinical practice? </li></ul><ul><...
2. Status – a bridge linking basic medical science and clinical medical science <ul><li>a synthesized marginal subject lin...
Pathophysiology - dialectics about human  knowledge on structure, function, metabolism Synthesize, analyze Normal body Sic...
hypokalemia <ul><li>K+ directly lost with intestinal juice  </li></ul><ul><li>diarrhea->extra cellular fluid↓-> effective ...
Pathophysiology is different from clinical subject Pathophysiology  Clinical subject  Kinds of disease Disorders of water ...
Heart failure Heart pump Myocardial contractility and diastolic function  load of myocardium Heart failure
Chronic bronchitis Cough, stethocatharsis, with/without asthma, last for two or more than two years, exclusive of other di...
3. contents pathophysiology conspectus of disease basic pathological process  Organic  pathophysiology Cellular and molecu...
conspectus of disease <ul><li>Concept of disease </li></ul><ul><li>Etiology of disease </li></ul><ul><li>Pathogenesis of d...
basic pathological process <ul><li>Refers to some common and collective  functional and/or metabolic and/or structural alt...
Organic  pathophysiology <ul><li>Mainly discuss the basic processes and mechanisms of the insufficiency or failure of impo...
Cellular and molecular pathophysiology <ul><li>Signal transduction and disease </li></ul><ul><li>Cell apoptosis in disease...
<ul><li>What is pathophysiology? </li></ul><ul><li>Why is pathophysiology important? </li></ul><ul><li>What contents are a...
How to Learn Pathophysiology <ul><li>Grasp the major points: causes,  pathogenesis,  alterations in metabolism and functio...
thank you!
Upcoming SlideShare
Loading in...5
×

Introduction

753

Published on

pathology

Published in: Health & Medicine, Technology
0 Comments
0 Likes
Statistics
Notes
  • Be the first to comment

  • Be the first to like this

No Downloads
Views
Total Views
753
On Slideshare
0
From Embeds
0
Number of Embeds
1
Actions
Shares
0
Downloads
21
Comments
0
Likes
0
Embeds 0
No embeds

No notes for slide

Transcript of "Introduction"

  1. 1. Pathophysiology Yu-Hong Jia, Ph.D Department of pathophysiology Dalian medical university
  2. 2. Introduction <ul><li>Concept </li></ul><ul><li>Goal </li></ul><ul><li>Status </li></ul><ul><li>Contents </li></ul>
  3. 3. Ⅰ. Concept <ul><li>Pathophysiology is a subject to explore the rule and mechanism of the origin and evolution of disease. </li></ul><ul><li>Applied physiology </li></ul><ul><ul><li>Clinical physiology </li></ul></ul><ul><ul><li>Medical physiology </li></ul></ul><ul><ul><li>Physiology of disease </li></ul></ul>
  4. 4. Ⅱ. Goal, status, contents <ul><li>Explore the general rule and mechanism of occurrence and development of disease </li></ul><ul><li>Explore the functional and metabolic alterations of sick body and the underlying mechanism </li></ul>1. Goal
  5. 5. investigation <ul><li>Question 1: Which basal subjects do you think are most useful for clinical practice? </li></ul><ul><li>Answer: pathophysiology and pharmacology </li></ul><ul><li>Question 2: Which basal subjects do you think are most difficult to learn? </li></ul><ul><li>Answer: biochemistry and pathophysiology </li></ul>
  6. 6. 2. Status – a bridge linking basic medical science and clinical medical science <ul><li>a synthesized marginal subject linked with many subjects of basic medical science. </li></ul><ul><li>a subject linked with clinical medical science </li></ul>? ? 2. Status Basic medical science Clinical medical science pathophysiology A bridge subject
  7. 7. Pathophysiology - dialectics about human knowledge on structure, function, metabolism Synthesize, analyze Normal body Sick body Knowledge after scientific thinking Stem from Apply to Anatomy, histology, physiology, biochemistry pathophysiology
  8. 8. hypokalemia <ul><li>K+ directly lost with intestinal juice </li></ul><ul><li>diarrhea->extra cellular fluid↓-> effective circulatory blood volume↓-> ADS↑->Na+ retention, K+ excretion -> loss of K+ through kidney↑ </li></ul>hypokalemia->myocardial resting membrane potential change->alteration of myocardial excitability, contractility, conductivity, automaticity->arrhythimia ? ? diarrhea arrhythmia
  9. 9. Pathophysiology is different from clinical subject Pathophysiology Clinical subject Kinds of disease Disorders of water and electrolyte metabolism Acid-base imbalance hypoxia shock gastroenteritis pneumonia Cause of disease Disturbance of normal physiological or biochemical process A wide range of extrinsic and intrinsic factors … …
  10. 10. Heart failure Heart pump Myocardial contractility and diastolic function load of myocardium Heart failure
  11. 11. Chronic bronchitis Cough, stethocatharsis, with/without asthma, last for two or more than two years, exclusive of other disease of heart and lung. The cause of chronic bronchitis: infection Smoking cold Immunological factor Diagnosis criteria:
  12. 12. 3. contents pathophysiology conspectus of disease basic pathological process Organic pathophysiology Cellular and molecular pathophysiology
  13. 13. conspectus of disease <ul><li>Concept of disease </li></ul><ul><li>Etiology of disease </li></ul><ul><li>Pathogenesis of disease </li></ul><ul><li>Outcome of disease </li></ul>
  14. 14. basic pathological process <ul><li>Refers to some common and collective functional and/or metabolic and/or structural alterations presented in many kinds of disease. </li></ul><ul><li>e.g. hypoxia, edema, stress, acidosis, fever, and so on </li></ul>
  15. 15. Organic pathophysiology <ul><li>Mainly discuss the basic processes and mechanisms of the insufficiency or failure of important organs in the body, i. e., heart, lung, liver, kidney and brain. </li></ul>
  16. 16. Cellular and molecular pathophysiology <ul><li>Signal transduction and disease </li></ul><ul><li>Cell apoptosis in disease </li></ul>
  17. 17. <ul><li>What is pathophysiology? </li></ul><ul><li>Why is pathophysiology important? </li></ul><ul><li>What contents are arranged in the book of pathophysiology? </li></ul>
  18. 18. How to Learn Pathophysiology <ul><li>Grasp the major points: causes, pathogenesis, alterations in metabolism and functions </li></ul><ul><li>Use dialectical thinking and methods, such as views of contradictory and unification, transformation, etc. </li></ul><ul><li>Selectively review related knowledge learned previously, such as physiology, biochemistry, molecular biology, immunology, pathology, and so on. </li></ul><ul><li>Pay attention to the lecture in class. </li></ul>
  19. 19. thank you!
  1. A particular slide catching your eye?

    Clipping is a handy way to collect important slides you want to go back to later.

×