AS Christmas Revision <ul><li>Aim to </li></ul><ul><li>Consolidate all the work from the advent term </li></ul><ul><li>Get...
Cells alive Scale Demo <ul><li>How Big Are Cells ? </li></ul><ul><li>Have a look at how big cells are…. </li></ul><ul><li>...
<ul><li>IMA triangle </li></ul>© Pearson Education Ltd 2008 This document may have been altered from the original Week 1
<ul><li>Calculations of actual size from magnification given </li></ul>© Pearson Education Ltd 2008 This document may have...
100 μ m = 0.1 mm
Inner Workings of a Cell  – soundtracked Inner Workings Harvard  – extended narrated version First click on the first link...
Mitochondria : Where  respiration  happens.  Energy  is generated in a chemical reaction between  glucose  and  oxygen Nuc...
Animal Cell
Plant Cell
Prokaryotic Cell
Some specialised cells – use your ppts to revise
<ul><li>Phospholipid molecule enlarged and (b) layer of phospholipids at the surface of water </li></ul>© Pearson Educatio...
<ul><li>A phospholipid bilayer </li></ul>© Pearson Education Ltd 2008 This document may have been altered from the origina...
<ul><li>The fluid mosaic model  – can you remember what each bit does??? </li></ul>© Pearson Education Ltd 2008 This docum...
Diffusion Diffusion is when something travels from an area of high concentration to an area of low concentration.  For exa...
Simple Diffusion
Osmosis Osmosis is the net movement of water from an area of its high concentration to an area of its low concentration ac...
Facilitated Diffusion – Channel Protein animation
Facilitated Diffusion – Carrier Protein animation
When a carrier or channel just isn’t big enough…  BULK TRANSPORT
Active Vs Passive Transport <ul><li>Youtube  summary of active  vs  passive transport </li></ul><ul><li>Now play this  GAM...
The Cell Cycle Mitosis is the division of a nucleus The cell cycle describes the life cycle of a cell (duh) Mitosis  is th...
Mitosis In case your wondering – blue stuff is chromosomes (hoescht stain) and green stuff is GFP modified microtubules (s...
More mitosis <ul><li>Great 3D animation inside a cell  – watch this and try to figure out what stage you’re at </li></ul><...
Stem Cells and differentiation How does an embryo go from all the same cell to about 210 cell types in an adult person?? W...
<ul><li>Finally, if you’ve got 20 mins then watch this excellent video about stem cells – it covers all the points. </li><...
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As christmas revision3

  1. 1. AS Christmas Revision <ul><li>Aim to </li></ul><ul><li>Consolidate all the work from the advent term </li></ul><ul><li>Get ready for some Mock Exams </li></ul>NOTE : to open a hyperlink – either click on it when you are in fullscreen mode or right click and then “open hyperlink” SECOND NOTE: this might not be exhaustive (ie have everything) so use this in conjuction with your syllabus! (also on intranet) to check you haven’t missed anything
  2. 2. Cells alive Scale Demo <ul><li>How Big Are Cells ? </li></ul><ul><li>Have a look at how big cells are…. </li></ul><ul><li>Remember: Actual Size = Image Size / Magnification </li></ul>
  3. 3. <ul><li>IMA triangle </li></ul>© Pearson Education Ltd 2008 This document may have been altered from the original Week 1
  4. 4. <ul><li>Calculations of actual size from magnification given </li></ul>© Pearson Education Ltd 2008 This document may have been altered from the original Week 1 Please note that magnification sizes are subject to variation on different screens Try it then move this box to see if you’re right
  5. 5. 100 μ m = 0.1 mm
  6. 6. Inner Workings of a Cell – soundtracked Inner Workings Harvard – extended narrated version First click on the first link then try and call out what organelles you are looking at aloud! (do this in a private place otherwise you will look like a nutcase) Then click on the second one to see if you were right Then try this link for professor MegaCell Game… Organelles Game Organelles Revision – use your powerpoints we made in class to revise. Then…
  7. 7. Mitochondria : Where respiration happens. Energy is generated in a chemical reaction between glucose and oxygen Nucleus: Contains DNA in big bundles called chromosomes . These carry your genes which control your characteristics Ribosomes: Your nucleus sends DNA messages to these instructing them what to build . They make proteins (including enzymes )
  8. 8. Animal Cell
  9. 9. Plant Cell
  10. 10. Prokaryotic Cell
  11. 11. Some specialised cells – use your ppts to revise
  12. 12. <ul><li>Phospholipid molecule enlarged and (b) layer of phospholipids at the surface of water </li></ul>© Pearson Education Ltd 2008 This document may have been altered from the original Week 3 Membranes Revision These will spontaneously form structures when mixed with water – a micelle, vesicle or a bilayer This is so that hydrophobic bits are shielded from water and hydrophilic bits are next to the water.. Heres a simulation
  13. 13. <ul><li>A phospholipid bilayer </li></ul>© Pearson Education Ltd 2008 This document may have been altered from the original Week 3 Great explanation of how phospholipids for bilayers Explanation
  14. 14. <ul><li>The fluid mosaic model – can you remember what each bit does??? </li></ul>© Pearson Education Ltd 2008 This document may have been altered from the original Some Youtube vids and simulations… Membrane transport overview
  15. 15. Diffusion Diffusion is when something travels from an area of high concentration to an area of low concentration. For example, consider the scent from a hamburger. Oxygen passes into cells by diffusion I took this slide from a GCSE powerpoint. For you at AS – remember only Small or Non-Polar (hydrophobic ) molecules can pass through the phospholipid bilayer The “scent particles” from this hamburger are in high concentration here: Eventually they will “diffuse” out into this area of low concentration:
  16. 16. Simple Diffusion
  17. 17. Osmosis Osmosis is the net movement of water from an area of its high concentration to an area of its low concentration across a partially-permeable membrane. Shuffle these around to get the definition – I’ve done the first one for you Remember : At AS level we talk about WATER POTENTIAL in terms of Ψ (psi) Maximum Ψ = 0 (pure water) Low Ψ = -500KPa (v. salty water) Note negative values
  18. 18. Facilitated Diffusion – Channel Protein animation
  19. 19. Facilitated Diffusion – Carrier Protein animation
  20. 20. When a carrier or channel just isn’t big enough… BULK TRANSPORT
  21. 21. Active Vs Passive Transport <ul><li>Youtube summary of active vs passive transport </li></ul><ul><li>Now play this GAME – </li></ul><ul><li>I must confess I only got 80% in 1;15 minutes here the first time around (its tough!) – some of it is beyond AS level but have a go </li></ul><ul><li>(hint: extrinsic = peripheral / surface) </li></ul>
  22. 22. The Cell Cycle Mitosis is the division of a nucleus The cell cycle describes the life cycle of a cell (duh) Mitosis is the birth of a new cell (stricly speaking mitosis and cytokinesis ) After this the cell must grow (G1) Then it decides whether to head towards division again (a checkpoint) Then DNA is copied ( S phase – part of interphase) Then it grows again and the centriole is copied ( G2 ) before it can do mitosis again
  23. 23. Mitosis In case your wondering – blue stuff is chromosomes (hoescht stain) and green stuff is GFP modified microtubules (spindle and cytoskeleton) 1.Interphase: DNA Copied 2. Prophase – chromosomes condensing 3. Metaphase – chromosomes line up on equator 4. Anaphase – chromosomes move to opposite poles 5. Telophase: chromosomes reach poles 5. Cytokinesis (not part of mitosis) = cell division A cell – start here AMAZING VIDS: Watch the chromosomes wiggle about Synchronised mitosis in a maggot ( urgh !)
  24. 24. More mitosis <ul><li>Great 3D animation inside a cell – watch this and try to figure out what stage you’re at </li></ul><ul><li>And then be amzed at these people who did mitosis through synchronised swimming (spot the centrioles and their green spindle fibres) </li></ul>
  25. 25. Stem Cells and differentiation How does an embryo go from all the same cell to about 210 cell types in an adult person?? Watch this zebrafish do it speeded up (you don’t need to know the annotations)
  26. 26. <ul><li>Finally, if you’ve got 20 mins then watch this excellent video about stem cells – it covers all the points. </li></ul><ul><li>http:// www.eurostemcell.org /films/a-stem-cell-story/English </li></ul>
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