Bone tumors muhammad 1

1,972 views

Published on

Bone Tumors EDU

Published in: Education
0 Comments
9 Likes
Statistics
Notes
  • Be the first to comment

No Downloads
Views
Total views
1,972
On SlideShare
0
From Embeds
0
Number of Embeds
9
Actions
Shares
0
Downloads
68
Comments
0
Likes
9
Embeds 0
No embeds

No notes for slide

Bone tumors muhammad 1

  1. 1. By Dr.Muhammad Ben Zulfiqar(PGR-1)
  2. 2. Clues by Appearance of Lesion Clues by Location of Lesion Clues by Density of Lesion Other Clues
  3. 3. Clues by Appearance of Lesion Patterns of Bone Destruction Periosteal Reactions Tumor Matrix Expansile Lesions of Bone
  4. 4. Clues by Appearance of Lesion Patterns of Bone Destruction Geographic Moth-eaten Permeative
  5. 5. Geographic Bone Destruction Destructive lesion with sharply defined border Implies a less-aggressive, more slow-growing, benign process Narrow transition zone
  6. 6. Patterns of Bone Destruction Geographic Moth-eaten Permeative Non-ossifying fibroma
  7. 7. Examples: • Non-ossifying fibroma • Chondromyxoid fibroma • Eosinophilic granuloma
  8. 8. Moth-eaten Bone Destruction Areas of destruction with ragged borders Implies more rapid growth  Probably a malignancy
  9. 9. Patterns of Bone Destruction Geographic Moth-eaten Permeative Multiple Myeloma
  10. 10. Moth-eaten Bone Destruction Examples: Myeloma Metastases Lymphoma Ewing’s sarcoma
  11. 11. Permeative Bone Destruction Ill-defined lesion with multiple “worm-holes” Spreads through marrow space Wide transition zone Implies an aggressive malignancy  Round-cell lesions
  12. 12. Patterns of Bone Destruction Geographic Moth-eaten Permeative Leukemia
  13. 13. Permeative Bone Destruction Examples: Lymphoma, leukemia Ewing’s Sarcoma Myeloma Osteomyelitis Neuroblastoma
  14. 14. Patterns of Bone Destruction Geographic Moth-eaten Permeative Less malignant More malignant
  15. 15. Periosteal Reactions Benign None Solid More aggressive or malignant Lamellated or onion peel Sunburst Codman’s triangle
  16. 16. Periosteal Reactions • Benign – None – Solid • Aggressive/malignant – onion-peel – Sunburst – Codman’s triangle Non-ossifying fibroma
  17. 17. Periosteal Reactions • Benign – None – Solid • Aggressive/malignant – onion-peel – Sunburst – Codman’s triangle Chronic osteomyelitis
  18. 18. Periosteal Reactions • Benign – None – Solid • Aggressive/malignant – onion-peel – Sunburst – Codman’s triangle Ewing sarcoma
  19. 19. Periosteal Reactions • Benign – None – Solid • Aggressive/malignant – onion-peel – Sunburst – Codman’s triangle Osteo-sarcoma
  20. 20. Periosteal Reactions • Benign – None – Solid • Aggressive/malignant – onion-peel – Sunburst – Codman’s triangle
  21. 21. Periosteal Reactions Solid onion-peelSunburst Codman’s triangle Less malignant More malignant
  22. 22. Tumor Matrix Osteoblastic Fluffy, cotton-like or cloud-like densities Osteosarcoma  Cartilaginous  Comma-shaped, punctate, annular, popcorn-like  Enchondroma, chondrosarcoma, chondromyxoid fibroma
  23. 23. Tumor Matrix Osteoblastic  Cartilaginous
  24. 24. Tumor Matrix  Osteoblastic  Fluffy, cotton-like or cloud-like densities as Osteosarcoma Cartilaginous Comma-shaped, punctate, annular, popcorn-like as Enchondroma, chondrosarcoma, chondromyxoid fibroma
  25. 25. Tumor Matrix Osteoblastic Cartilaginous Chondrosarcoma
  26. 26. Expansile Lesions of Bone • Multiple myeloma • Mets • Brown tumor • Enchondroma • Aneurysmal bone cyst • Fibrous dysplasia
  27. 27. Expansile Lesions of Bone Multiple myeloma Mets Brown tumor Enchondroma Aneurysmal bone cyst Fibrous dysplasia
  28. 28. Multiple myeloma Mets Brown tumor Enchondroma Aneurysmal bone cyst Fibrous dysplasia Expansile Lesions of Bone Renal cell carcinoma
  29. 29. Multiple myeloma Mets Brown tumor Enchondroma Aneurysmal bone cyst Fibrous dysplasia Expansile Lesions of Bone
  30. 30. Multiple myeloma Mets Brown tumor Enchondroma Aneurysmal bone cyst Fibrous dysplasia Expansile Lesions of Bone
  31. 31. Multiple myeloma Mets Brown tumor Enchondroma Aneurysmal bone cyst Fibrous dysplasia Expansile Lesions of Bone
  32. 32. Multiple myeloma Mets Brown tumor Enchondroma Aneurysmal bone cyst Fibrous dysplasia Expansile Lesions of Bone
  33. 33. Clues by Location of Lesion • In the Transverse Plane • In the Longitudinal Plane • Characteristic Locations by tumors • Characteristic Tumors by Body Site – Pelvic Lesions – Expansile Rib Lesions – Lesions of the Spine
  34. 34. In the Transverse Plane . . .
  35. 35. In the longitudinal Plane Epiphyseal GCT, chondroblastoma Metaphyseal Osteomyelitis, osteo-and chondrosarcoma Diaphyseal Round cell lesions, ABC, enchondroma
  36. 36. Characteristic Locations Simple bone cyst Proximal humerus  Chondroblastoma Epiphyses  Giant Cell tumor Epiphyses  Adamantinoma Tibia  Chordoma Sacrum, clivus  Osteoblastoma Spine, posterior
  37. 37. Characteristic Locations  Simple bone cyst Proximal humerus Chondroblastoma Epiphyses  Giant Cell tumor Epiphyses  Adamantinoma Tibia  Chordoma Sacrum, clivus  Osteoblastoma Spine, posterior
  38. 38.  Simple bone cyst Proximal humerus  Chondroblastoma Epiphyses Giant Cell tumor Epiphyses  Adamantinoma Tibia  Chordoma Sacrum, clivus  Osteoblastoma Spine, posterior Characteristic Locations
  39. 39.  Simple bone cyst Proximal humerus  Chondroblastoma Epiphyses  Giant Cell tumor Epiphyses Adamantinoma Tibia  Chordoma Sacrum, clivus  Osteoblastoma Spine, posterior Characteristic Locations
  40. 40.  Simple bone cyst Proximal humerus  Chondroblastoma Epiphyses  Giant Cell tumor Epiphyses  Adamantinoma Tibia Chordoma Sacrum, clivus  Osteoblastoma Spine, posterior Characteristic Locations
  41. 41.  Simple bone cyst Proximal humerus  Chondroblastoma Epiphyses  Giant Cell tumor Epiphyses  Adamantinoma Tibia  Chordoma Sacrum, clivus Osteoblastoma Spine, posterior Characteristic Locations
  42. 42. Clues by Density of Lesion Sclerotic Cortical Lesions Lytic Lesions in Children Lytic Lesions in Adults Blastic Lesions in Children Blastic Lesions in Adults
  43. 43. Sclerotic Cortical Lesions Osteoid osteoma Brodie’s abscess
  44. 44. Sclerotic Cortical Lesions Osteoid osteoma Brodie’s abscess
  45. 45. Lytic Lesions in Children Eosinophilic granuloma Leukemia
  46. 46. Lytic Lesions in Children Eosinophilic granuloma Leukemia
  47. 47. Lytic Lesions in Adults Metastatic lesions Lung Renal Thyroid Multiple myeloma Primary bone tumor Metastatic thyroid carcinoma
  48. 48. Lytic Lesions in Adults Metastatic lesions Lung Renal Thyroid Multiple myeloma Primary bone tumor
  49. 49. Lytic Lesions in Adults Metastatic lesions Lung Renal Thyroid Multiple myeloma Primary bone tumor Chondrosarcoma
  50. 50. Blastic Lesions in Children Lymphoma
  51. 51. Blastic Lesions in Adults Metastatic disease Breast –female Prostate –male Lymphoma Paget’s disease Fluorosis Prostatic Ca.
  52. 52. Blastic Lesions in Adults Metastatic disease  Breast –female  Prostate –male Lymphoma Paget’s disease Fluorosis
  53. 53. Blastic Lesions in Adults Metastatic disease  Breast –female  Prostate –male Lymphoma Paget’s disease Fluorosis
  54. 54. Blastic Lesions in Adults Metastatic disease  Breast –female  Prostate –male Lymphoma Paget’s disease Fluorosis
  55. 55. Other Clues Soft Tissue Extension Benign vs. Malignant
  56. 56. Soft Tissue Extension Usually implies malignancy  More likely to form discrete soft tissue mass Benign conditions with soft tissue extension  Osteomyelitis  Usually infiltration of fat
  57. 57. Lymphoma Osteosarcoma Soft Tissue Extension
  58. 58. Benign vs. Malignant
  59. 59. Thank You

×