Penicillin_Geraldine

394 views
242 views

Published on

0 Comments
0 Likes
Statistics
Notes
  • Be the first to comment

  • Be the first to like this

No Downloads
Views
Total views
394
On SlideShare
0
From Embeds
0
Number of Embeds
139
Actions
Shares
0
Downloads
2
Comments
0
Likes
0
Embeds 0
No embeds

No notes for slide

Penicillin_Geraldine

  1. 1. WHAT IS PENICILLIN? Penicillin (sometimes abbreviated PCN or pen) is a group of antibiotics derived from Penicillium fungi, including penicillin G, procaine penicillin, benzathine penicillin, and penicillin V. Penicillin antibiotics are historically significant because they are the first drugs that were effective against many previously serious diseases, such as syphilis, and infections caused by staphylococci and streptococci. All penicillins are β-lactam antibiotics and are used in the treatment of bacterial infections caused by susceptible, usually grampositive, organisms.
  2. 2. PRODUCTION OF PENICILLIN Discovered by accident in 1928 by Alexander Fleming During world war II importance realized, as penicillin had been used to treat many wounded soldiers.
  3. 3. HOW PENICILLIN WORKS? -Resembles a protein needed for production of cell wall. -Penicillin binds to cell wall of bacteria, prevent peptide chains.
  4. 4. MOA OF PENICILLIN All penicillin like antibiotics inhibit sythensis of peptidoglycan, an essential part of the cell wall. they do not interfere with the sythensis of other intracellular components. These antibiotics do not affect human cells because human cells do not have cell walls.
  5. 5. PRIMARY AND SECONDARY METABOLITES Primary metabolites are produced during active cell growth, and secondary metabolites are produced near the onset of stationary phase.

×