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03   respiratory system2
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03 respiratory system2






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  • http://www.youtube.com/watch?v=HiT621PrrO0
  • Surfactant also keeps gas exchange surfaces moist

03   respiratory system2 03 respiratory system2 Presentation Transcript

  • RESPIRATORY SYSTEM As air enters the body, it enters through the following structures: 1) Nose (or oral cavity if you breathe with your mouth) 2) Pharynx 3) Larynx 4) Trachea
    • Nose:
    • The nasal cavity has 3 main functions:
    • Cleans the air – nostrils contain tiny hairs
    • 2) Warms the air – the epithelial lining and turbinate bones have capillaries that warm the air.
    • 3) Moisture – the turbinates are lined with a thin membrane that secretes a mucus that moisten the air coming in.
    • Nose turbinates:
    • Thin bones
    • Increase surface area
    • Allows air to reach more warmed , moist surfaces (results in cleaner, warmer air)
  • RESPIRATORY SYSTEM Larynx (“voice box”) Houses the vocal cords.
  • RESPIRATORY SYSTEM Larynx (“voice box”) Act like strings of a guitar ( relaxed for lower pitch , and tightened for higher pitch ) Male vocal cords grow during puberty, like thicker guitar strings, causing voice to deepen
    • Vocal cord inflammation (laryngitis)
    • Can be caused by
    • infection (usually viral)
    • Smoking
    • Regurgitation of stomach acid during vomiting
    Can also be caused by overuse
  • RESPIRATORY SYSTEM Vocal cord nodules Growths on the vocal cords. (from constant straining of voices)
  • RESPIRATORY SYSTEM Trachea : The trachea is lined with ciliated cells , which brush foreign particles back upwards It also maintains its rigidity thanks to cartilage (soft “bone”)
  • RESPIRATORY SYSTEM Trachea : The epithelium of the trachea has mucous cells (Goblet cells) and cilia . The mucus traps foreign particles , and cilia brush the mucus up the trachea (like mopping the floor)
  • RESPIRATORY SYSTEM Trachea : We sneeze to expel mucus that has trapped foreign particles, as well as other inhaled particles
  • RESPIRATORY SYSTEM Bronchus : The trachea leads into the bronchus ( like a fork in the road ), which further divides into smaller bronchi . The structures are also reinforced with cartilage .
  • RESPIRATORY SYSTEM Bronchi : The bronchi branch into the lungs, eventually reaching the alveoli .
  • RESPIRATORY SYSTEM Alveoli : The alveoli (singular: alveolus ) are spherical hollow cavities which increase surface area for gas exchange. Capillaries (tiny blood vessels) line the alveoli to make gas exchange possible.
  • RESPIRATORY SYSTEM Alveoli : Low-oxygen blood ( bluish color ) travels to the alveoli where carbon dioxide is released. At the same time, oxygen from inhaled air enters the blood, making it look red .
  • RESPIRATORY SYSTEM Gas exchange: Carbon dioxide (a waste product) leaves the blood vessel into the alveolus. Oxygen goes into the blood vessel. CO 2 CO 2 CO 2 CO 2 O 2 O 2 O 2 O 2 Blood vessel Alveolus
  • RESPIRATORY SYSTEM Lung surfactant: Surfactant helps to lower surface tension in the airways and this helps keep the lung alveoli open . Also has immune cells to defend against bacteria, viruses, and other infectious agents.
  • RESPIRATORY SYSTEM The Lung: Each lung is divided into lobes. The right lung has three lobes. The left lung has two lobes (to accommodate the heart).
  • RESPIRATORY SYSTEM Pleura: The lungs are protected by a layer called the pleura . Pleura is a flexible membrane that permits the lung to expand and contract during inspiration and expiration .
  • RESPIRATORY SYSTEM Breathing: When we breathe we use two sets of muscles: 1) Diaphragm – separates the lungs (thoracic cavity) from the stomach and liver 2) Intercostal muscles (ribcage muscles)
    • Breathing:
      • Inspiration – taking air into the lungs ( inhalation )
      • Expiration – the act of breathing out ( exhalation )
    • 2 types of respiration
      • External respiration
      • - The exchange of oxygen and carbon dioxide between the air (alveoli) and blood
    • 2 types of respiration
      • 2) Internal respiration
      • -The exchange of oxygen and carbon dioxide between the blood and the cells.
    • Lung volumes
    • Lung volumes
    • Tidal Volume – the volume of air inhaled and exhaled in a normal breathing movement.
    • Inspiratory Reserve Volume – the additional volume of air that can be taken in, beyond a regular or tidal inhalation.
    • Lung volumes
    • Expiratory Reserve Volume – the additional volume that can be forced out of the lungs, beyond a regular or tidal exhalation.
    • Vital Capacity – the total volume of gas that can be moved in or out of the lungs.
    Equation: Tidal volume + inspiratory reserve volume + expiratory reserve volume = vital capacity
    • Lung volumes
    • Residual Volume – the amount of gas that remains in the lungs and the passageways of the respiratory system even after a full exhalation.
    • This volume NEVER leaves the respiratory system, if it did the lungs would collapse.
    • Lung volumes
    • Spirometer – a device that measures the amount of air inspired and expired by the lungs.
    • Lung volumes
    • Factors that affect lung volumes:
    • Sex
    • Height
    • Smoking history
    • Fitness/athleticism
    • Altitude*
    • * Air at higher altitudes has less oxygen, so lung volume increases to allow more air into the lungs
    Larger volumes Smaller volumes males females taller people shorter people non-smokers smokers athletes non-athletes people living at high altitudes people living at low altitudes
  • RESPIRATORY SYSTEM Lung volumes A highly trained athlete may have a lung capacity as great at six and a half liters, nearly 50 percent greater than an average adult. Our lungs can be trained over time to take in more oxygen as our bodies need it. Exercise that improves lung capacity is called aerobic exercise . Increasing the capacity of your lungs will mean that you need to breathe fewer times in a minute for your body to receive the same amount of oxygen as a person with smaller lung capacity.
  • RESPIRATORY SYSTEM Lung volumes and disease: 2 types: Restrictive: Lung volumes are decreased  ex: pulmonary fibrosis
  • RESPIRATORY SYSTEM Lung volumes and disease: 2 types: Obstructive: Lung volumes are normal but flow rates are impeded  ex: asthma
  • RESPIRATORY SYSTEM ASTHMA: Air pollution can lead to asthma. Asthma is a chronic , inflammatory disease resulting in reversible airflow obstruction. Short-term treatment: Bronchiodilators Long-term treatment: Anti-inflammatory drugs , bronchiodilators
  • RESPIRATORY SYSTEM SMOKING: Smoking injures the cilia of the trachea, and alters the efficiency of their beating so they cannot remove foreign particles (i.e. bacteria ) as effectively. Tar builds up in the lungs from smoking. Tar decreases respiration.
  • RESPIRATORY SYSTEM SMOKING: Smoking causes emphysema . - alveoli walls fuse together, which reduces the surface area for gas exchange.
    • SMOKING:
    • Lung with emphysema.
    • Treatment:
    • stop smoking
    • surgery, transplant
  • RESPIRATORY SYSTEM SMOKING: Lung cancer is associated with smoking.
    • Pneumonia:
    • Infection of the lungs, leading to fluid filling the alveolar spaces.
    • Caused by:
    • Bacteria
    • Viruses
    • Fungi
    • Other microorganisms
    • Treated with antibiotics
    • Bronchitis:
    • Inflammation of bronchi.
    • Caused by:
    • Viruses
    • Bacteria
    • Pollution
    • Dust
    • Smoke
    • These irritate the bronchi, causing them to swell .
    Treatment: Stop smoking, antibiotics (if caused by bacteria)
    • Laryngitis:
    • Inflammation of the vocal cords.
    • Caused by:
    • Overuse
    • Irritation
    • Respiratory infection
    • Treatment includes resting the voice and prescription medication.
  • RESPIRATORY SYSTEM Hypoxia (altitude sickness): The body cannot get enough oxygen from the air to meet metabolic demands. Symptoms: Shortness of breath, headaches, nausea Short-term adaptation: Breathing rate increases Long-term adaptations: Body produces more red blood cells; more capillary networks