Parkinson’s disease & neuromuscular disorders


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Parkinson’s disease & neuromuscular disorders

  1. 1. 16/11/2012 PARKINSONS’ &Neuromuscular disordersA Talk for the Scarborough chapter of the Parkinson’s Society of Canada. Morwenna Given BA MA (Oxon) BSC m.OHA BHG RH 1 ©
  2. 2. 2 16/11/2012 WHO AM I? I am a medical herbalist, trained in University, Hospital and clinics in the UK & USA With a practise in downtown Toronto focussing on: Chronic auto immune diseases including MS, Cancer, Alzheimers, diabetes, and womens’ issues ©
  3. 3. 3 16/11/2012 What Do I Do?A person who treats medical disease ‘wholistically’ on an evidence based basis with whole plant extracts A person who treats the cause of the problem not just the symptom We are specialists in the use of medicinal plants and their ability to resolve disease ©
  4. 4. 4 16/11/2012 What is Parkinsons Parkinson’s disease belongs to a group of disorders which affect the brain Other group disorders include ALS, MS, Alzheimers and dementia Most serious movement disorder in the world characterised by A loss of dopaminergic neurons in the brain ( substantia nigra )resulting in signs and symptoms negatively impacting on life ©
  5. 5. 5 16/11/2012 Common Pathologies for neurodegenerative disorders All these disorders have much in common. Aetiology is surprising uniformBrain Nerve. 2012 Jun;64(6):675-9.Are neurodegenerative diseases "protein cancers"?.Hasegawa M.Department of Neuropathology and Cell Biology, TokyoMetropolitan Institute of Medical Science, Japan. ©
  6. 6. 6 16/11/2012 MICROBIOME Auto immunity diseases arise from the gut Kirsten Berer Max Planck Institute Freiburg Gut bacterias trigger the reaction that causes the body’s immune system to misbehave – which is why amyloid deposits in the brain are a late stage feature…….Parkinsons develops years before signs and symptoms lead to a diagnosis ©
  7. 7. 7 16/11/2012YOU ARE WHAT YOU EAT The microbiome is the most exciting development in science in the last 50 yrs. What you eat is totally under your control and preventable medicine There will never be a drug for bacteria as they mutate like viruses Most plants have anti bacterial and anti viral properties! ©
  8. 8. 8 16/11/2012 Diseases of Excess Longer life spans – 25 more years Diet – heavily processed with grains & sugar Lack of exercise – the motor car Alcohol smoking and stress ©
  9. 9. 9 16/11/2012 Symptoms Gait and motor symptoms – petit pas Depression and fatigue Hearing, taste, smell abnormalities Bowell dysfunction Urinary dysfunction Respiratory difficulties Restless legs Dementia ©
  10. 10. 10 16/11/2012 Exercise "It is clear from this study and others that physical performance in late life plays an incredibly important role in our cognitive health," said Dr. Erickson. "Although more research is needed into the causal mechanisms and pathways by which this works, it is clear that physical performance in late life is critical for retaining a healthy brain." Arch Neurol. Published online October 22, 2012. Exercise May Beat Mental Activity in Preserving Cognition. Medscape. Oct 24, 2012. ©
  11. 11. 11 16/11/2012Arch Neurol. Published online November 5, 2012 research has shown that exercise programs among patients with neurologic disorders "increase the patients sense of self-efficacy, their sense of involvement in their care and overall belief in their abilities to perform certain activities." “… patient involvement leads to higher satisfaction with care, and greater likelihood of following provider recommendations,". "In essence, exercise puts the patient — not a pill — at the center of care, which is exactly where patients want and ought to be." ©
  12. 12. 12 16/11/2012 Diet Gluten intolerance may be a factor Hybridised grains and overconsumption Poor nutrition – lack of key vitamins, minerals in immunocompromised patients directly relates to poor function Inflammation mediated memory dysfunction and effects of a ketogenic diet Kim do et al Plos One 2012 7(5) 35476 High glucose levels affect the HPA ©
  13. 13. 13 16/11/2012 Sugar Like all diseases of excess sugar plays a key role in destabilising the body’s normal mechanisms including brain function Excess sugar is derived from an inappropriate diet i.e. one high in grains Insulin resistance a hall mark of co morbidities e.g. PCOS High circulating levels of glucose affect the brain J.Physiol 2012 590:2485-2499 Gomez-Pinella ©
  14. 14. 14 16/11/2012 CAN I HELP?Yes! How do I treat ? I review all aspects of the health of the person Diet, exercise Drugs, supplements Co-existing conditions – obesity, diabetes, women’s issues, impotence, constipation etc. ©
  15. 15. 15 16/11/2012 Review Medications & their side effects Diet / exercise/ vit d Symptoms and impact on life thyroid ©
  16. 16. 16 16/11/2012 Vitamin D Ontario is well known for its lack of vitamin D in the population – it is recognised to be endemic Reduced vitamin D is associated with the geographic incidence of neuromuscular disorders Loss/Lack of vitamin D affects bones, muscles, thyroid, liver etc. ©
  17. 17. 17 16/11/2012 Plant Medicine Thereare a number of plants which have been shown to inhibit the development of Parkinsons and other neurological disorders Plants are the basis for most medicine today ©
  18. 18. 18 16/11/2012 Selection of Plants Turmeric – Curcuma longa Centella asiactica Macuna Puriens Brahmi – Bacopa monnieri Panax ginseng Kudzu Pueria Lobata ©
  19. 19. 19 16/11/2012 THEY WORK! Reversible worsening of symptoms after taking Cat’s claw ( Clin.Neuropharmacol 2008)A diversity of compounds isolated from herbal materialswere reported to be effective on neurotoxic models of PDby modulating multiple key events or signaling pathwaysimplicated in the pathogenesis of PD j.Ethnopharmacol2012 feb 15  We use a combination of plants in a tincture to synergise and maximise effectiveness which is not possible in a conventional drug ©
  20. 20. 20 16/11/2012 Key Missing Nutrients Our locally grown vegetables do not have sufficient zinc, selenium Most people do not eat enough fish- iodine Most people eat too much processed flour based food – inhibiting bromine. All of which is interesting considering that is now recognised neurological diseases starts in the gut. ©
  21. 21. 21 16/11/2012 Carers Therole of carers is vital to minimising the progression of Parkinson’s It is very important the carer must not neglect their own health The basic advice for Parkinsons’ in respect of diet/exercise is the same for carer’s! ©
  22. 22. 22 16/11/2012 Drugs not OTC PLEASE NOTE: IT IS ADVISED, THAT ANY PLANTS MENTIONED IN THIS TALK, ARE ONLY USED UNDER PROFESSIONAL GUIDANCE. BOTANICAL MEDICINE AS COMPOUNDED BY A PROFESSIONAL IS NOT AVAILABLE OVER THE RETAIL COUNTER. It is not advisable to self treat A professional: will recognise all the issues within the body ; Select herbs that will impact positively on these issues without causing problems in order to co exist with other medications ©
  23. 23. 23 16/11/2012 References www. Pubmed, Science directIhave a full list of references for those who are interested – if you would like either to email me or put your name down tonight I will send them to you. It is several pages! ©