Workflows<br />Two workflows have been developed with Brig Mecham from Sage Bionetworks<br />
MetaGEO project<br />The 2 workflows have been developed in the context ofBrig’s MetaGEO project which normalises gene expression data sets in the GEO database<br />The normalised data sets enable meta-analyses, e.g. identification of disease signatures<br />Difference between MetaGEO and other similar projects is that all research objects in MetaGEO is open access<br />Data, results, intermediate results, data analysis and integration procedures, etc<br />Enhances the trust of MetaGEO data by researchers<br />For more information on MetaGEO, see Brig’s slides on SageCite wiki<br />
Workflow 1<br />This workflow produces an annotation library that is used to map gene probes on Affymetrix chips to a specific gene for an organism<br />The library is used as part of the curation step for gene expression data sets in GEO<br />
Workflow 2<br />This workflow performs normalisation and inference analysis on GEO data<br />Produces normalised data and statistics of gene expression<br />
Workflow citation demonstrator<br />Developed a Taverna plugin for registering workflow results with a DOI using DataCite service<br />
Workflow citation demonstrator<br />Plugin provides an operation in Taverna’s service palette that can be incorporated into workflows to register a data set with a DOI via DataCite<br />
Registration of data<br />To register data, the plugin provides it with a DOI<br />For example:<br />10.5520/SAGECITE-1<br />
SageCite demo repository web site<br />The plugin stores data in a local sqlite database and creates a web page on the SageCite demo repository web site to display data<br />
Registration of data using DataCite<br />The plugin uses the DOI to register the data on DataCite using its Web API<br />
Registration of data using DataCite<br />Clicking on the DOI link takes you to the web page for the data on the SageCite demo repository site<br />
To do and issues<br />Need to register metadata for workflow results using DataCite API<br />Large size of data generated from Brig’s pipelines sometimes breaks plugin<br />
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