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Cystadenoma, cystadenocarcinoma (>50% for serous, ~5% for mucinous)
Granulosa cell tumor (15-20%)
Theca cell tumor (<1%)
10/04/11 template from www.brainybetty.com copyright 2006 Ovarian neoplasms may be primarily cystic, solid, or mixed. Some are benign, some are malignant. Some produce enough hormone to cause symptoms for the patient. Some examples of these shown below. Primarily Cystic Primarily Solid Mixed
Mucinous cystadenoma (benign, sometimes grow quite large)
Ovarian carcinoma can spread by local extension, lymphatic invasion, intraperitoneal implantation, hematogenous dissemination, and transdiaphragmatic passage.
Intraperitoneal dissemination is the most common and recognized characteristic of ovarian cancer.
Malignant cells can implant anywhere in the peritoneal cavity but are more likely to implant in sites of stasis along the peritoneal fluid circulation.
10/04/11 template from www.brainybetty.com copyright 2006 Designation Definition Stage I Cancer limited to the ovaries IA Growth limited to one ovary, capsule intact, no malignant ascites, no tumor on external surface IB Growth limited to both ovaries, capsule intact, no malignant ascites, no tumor on external surface IC As for IA or IB but with surface growth, ruptured capsule (before or during surgery), positive washings, or malignant ascites Stage II Growth involving one or both ovaries with pelvic extension IIA Extension and/or metastases to the uterus and/or tubes IIB Extension to other pelvic organs IIC As for IIA or IIB but with surface growth, ruptured capsule (before or during surgery), positive washings, or malignant ascites Stage III Tumor involving one or both ovaries with peritoneal implants outside the pelvis and/or positive retroperitoneal or inguinal nodes; liver capsule involvement IIIA Tumor grossly limited to the true pelvis with negative nodes but microscopic seeding of abdominal peritoneal surfaces IIIB Abdominal peritoneal implants, but none exceeding 2 cm; nodes negative IIIC Abdominal peritoneal implants larger than 2 cm and/or positive retroperitoneal or inguinal nodes Stage IV Tumor involving one or both ovaries with distant metastases; pleural effusions must be demonstrated to harbor malignant cells; liver parenchymal involvement
Classification of Ovarian Tumors, Surface Epithelial Tumors
- Serous Tumors : Benign ,Borderline and malignant
- Mucinous T. : Benign ,Borderline , and malignant
- Endometrioid T . : Benign, Borderline, and malignant