Guenter Huhle, Janssen-Cilag, Germany, Chronic Diseases

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Guenter Huhle, Janssen-Cilag, Germany, shares his views on Chronic Diseases - The Everyday Epidemic

Guenter Huhle, Janssen-Cilag, Germany, shares his views on Chronic Diseases - The Everyday Epidemic

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  • 1. Chronic Diseases – The Everyday Epidemic Explore new ways to address leading causes of morbidity and mortality in the world. INSEAD Healthcare Alumni Summit 2010 08. October 2010 Guenter Huhle, MD, PhD, MSci Executive board member and Medical Director, Germany Medical Affairs Leader Metabolics, Europe, Middle East & Africa
  • 2. Type 2 Diabetes: A Devastating Global Epidemic Diabetes care accounts for 2- 7% of the total national Worldwide Population: health care budgets of 6.6 Billion1 western European countries3 The prevalence of type 2 diabetes worldwide is set to increase to 366 million by >220 million people 20304 diagnosed 2 Each year more than three million deaths are attributable to diabetes4 Data sources: 1US Census Bureau at: http://www.census.gov/cgi-bin/ipc/idbagg ; 2 World Health Organisation Fact Sheet No. 312: What is Diabetes? Available at: http://www.who.int/mediacentre/factsheets/fs312/en/;3Diabetes Action Now Booklet, WHO, 2009 http://www.who.int/diabetes/BOOKLET_HTML/en/print.html; 3International Diabetes Federation, Diabetes & Metabolism, 2003, vol. 29 (2), no 4 (120 p.) (84 ref.), pp. 6S9-6S18, accessed at http://cat.inist.fr/?aModele=afficheN&cpsidt=15155231; 4World Diabetes Foundation, 2008, accessed at http://www.worlddiabetesfoundation.org/composite-976.htm 3
  • 3. Type 2 Diabetes: A complex disease Obesity IFG* Diabetes Uncontrolled Hyperglycemia 350 300 Postmeal 250 Glucose Glucose 200 Fasting (mg/dL) 150 Glucose 100 50 250 Insulin Resistance 200 Relative 150 Function (%) 100 Insulin Level 50 -Cell Failure 0 -10 -5 0 5 10 15 20 25 30 Years of Diabetes *IFG=impaired fasting glucose.
  • 4. Type 2 Diabetes: Treat to Failure Insulin Oral agents + insulin Combo of oral agents Oral agent Diet and exercise Progression of disease
  • 5. From product development and market access…
  • 6. In a market with projected increases in government spending on Health Care globally... Source: National Center for Policy Analysis, 2006.
  • 7. To an integrated Health Value management, addressing the deficiencies in health care From... Via ...To Lack of prevention Integrated Health Care Solutions & Value Management Improvement in Product focus • Prevention Data • Treatment collection & quality Over-hospitalization Prevention Knowledge & Resource & Treatment Management • Treatment Steering for People effectiveness consumption • Cost efficiency Inefficient processes & & interfaces Controlling Integrated & Evaluation Solutions Lack of cooperation
  • 8. 9