metagenomics bacteria genomics science bioinformatics arrowhead lake microbial 2008 review conference poster biotorrents research metagenomics 16s microbiome bioinformatics ievobio software ecology microbiology picrust function 16s ihmc2012 dna proteins unknown function bitttorrent open science summit 2010 open data communityprofiling genes microbedb ncbi mysql hmmer defense genomic islands
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