Slides for nfc cluster feb 6 v3

NFC In SmartphonesTransforms Healthcare February 6, 2012 6:00-8:30pm Sponsored by: #MITFORUM#NFCClusterBos

Agenda• Welcome• Perspective from Asia: NFC in Japan National Project of Telehealth in Home Healthcare Prof. Masanori Akiyama M.D., Ph.D.• Technology Presentations Sandra Eliott, Director, Meridian Health/IMPak Hajo Hanse, CTO, Qolpac John Peeters, CEO, Gentag• Panel Discussion Nick Holland, Senior Analyst, Yankee Group Charles Walton, Chief Operating Officer, INSIDE Secure Gagan Puranik, Assocaite Director, Verizon Moderator: Joseph Ternullo, JD, MPH, Director, Partners• Reception sponsored by INSIDE Secure (plus raffles!) #MITFORUM #NFCClusterBos

Thank you to tonight’s sponsor Reception 8:30pm – 9:30 pm Catalyst Restaurant, 300 Technology Square 5 minute walk! Right on Vassar street to Main Street, left on Main for one block, cross the street to Catalyst #MITFORUM#NFCClusterBos

EducateInspireConnectAssist #MITFORUM #NFCClusterBos Twitter: #mitforumAdvise Twitter: #nfcclusterbos

Forum Program Tracks Concept & CEO Series Innovation Series Special Interest GroupsStart-up Clinics Panel & Senior Exec Highlights • Sector Specific Topics Audience Training Markets for • Connect CommunityFeedback on Entrepreneurial • Strengthen Biz Plan Opportunities CollaborationOnce/month Three Options 8-10 events/ Present SIGs • Get Smart – 1 year • Auto-ID & Sensing topic, 2 hours • Digital Media • Start Smart – 8 • Energy week workshop • Games • Lead Smart – • Life Sciences & One Year Healthcare Program • Software #MITFORUM #NFCClusterBos

Upcoming Programs Register at www.mitforumcambridge.orgDate EventFeb. 6 NFC In Smartphones Transforms HealthcareFeb. 8 Innovation Series Event: The Future of the Personal GenomeFeb. 15 Forum Members After Work Networking ReceptionFeb. 16 Concept Clinic with MosecFeb. 16 Energy SIG Event: Sustainable Transportation in our Lifetime? #MITFORUM #NFCClusterBos

Forum Members #MITFORUM#NFCClusterBos

Annual Sponsors #MITFORUM#NFCClusterBos

NFC Cluster Boston• Stimulate innovation using NFC• Host educational programs, workshops, activities, and exhibits (4–6 / year)• Over 50 supporting groups• Looking for program team volunteers• Next event is March 28• Bookmark our home page @nfcclusterbos #nfcclusterbos

Follow theNFC Cluster Boston @nfcclusterbos, #nfcclusterbos Like us on Facebook Join our LinkedIn group #MITFORUM#NFCClusterBos

Thank You• Program Committee (Volunteers)• Speakers• MIT Enterprise Forum staff• Attendees #MITFORUM #NFCClusterBos

Explosion in NFC Uses for Health Care Photos: courtesy Gentag, Meridian Health, Quolpac, Boston Life Labs

Perspective from Asia NFC in Japan: National Project of Telehealth in Home HealthcareProfessor Masanori at Ministry of Internal Affairs Akiyama and Communications #MITFORUM #NFCClusterBos

NFC in Japan: National Project of Telehealth inHome Healthcare at Ministry of Internal Affairsand Communications” Masanori Akiyama M.D., Ph.D. Policy Alternatives Research Institute The University of Tokyo February 6, 2012 @MIT

AgendaAging Issue and Crisis in Healthcare SystemHealthcare System Reform in Japan ˗ Average of hospital admission stay; about 17days to 7-10days, Shortening of 7 daysfrom Hospital wards to Home ˗ Tele-healthcareInsufficient trustworthiness of IT and Expensive cost of initial investment for IT introduction ˗ Protect impersonator ˗ Cloud computing © 2012 Masanori Akiyama. All Rights Reserved 15

Improving the Health Condition Transition of Mortality Rate by Cause Infant Mortality Rate of Disease (%, of thousand birth) (% ,of 100 thousands person)200 200180 180160140 160120 140 tuberculosis100 120 hypertensive disorder 80 100 60 cerebrovascular disease 80 40 asthma 20 60 gastric ulcer duodenal ulcer 0 40 1899 1904 1909 1914 1919 1924 1929 1934 1939 1947 1952 1957 1962 1967 1972 1977 1982 1987 1992 1997 2002 2007 20 infant mortality rate % of thousand birth) the rate to total death 0 1947 1951 1955 1959 1963 1967 1971 1975 1979 1983 1987 1991 1995 1999 2003 2007 Source: Vital statistics(2009) © 2012 Masanori Akiyama. All Rights Reserved 17

Life Expectancy at Birth, Both Sexes Combined (years) 90 80 70 Japan China Indoneshia 60 Philippines Australia Malaysia 50 Republic of Korea Singapore Thailand 40 30 Population Division of the Department of Economic and Social Affairs of the United Nations Secretariat, World Population Prospects: The 2008 Revision, http://esa.un.org/unpp, Wednesday, August 25, 2010; 4:28:54 AM. © 2012 Masanori Akiyama. All Rights Reserved 18

Aging and Crisis in Healthcare System (1)• Population age structure has rapidly changed toward a large older generation since 1990 (especially over 65 years old). In Japan, aging has been accelerated by universal public healthcare insurance, progress of healthcare technology and downward trend in the birthrate with modernization.• With populations aging, growth rate of healthcare cost exceeds economic growth rate and existing healthcare system is at risk of failure.• Components of Crisis 1)More people in aging - Structural change in disease from infectious to chronic Living for longer time with complicated diseases thanks to advanced medicine 2)Population decline - Local healthcare became weak because of gap between demand and supply to healthcare service in thinly populated rural areas, advanced medical technology and hospitals aggregated for affording the technology. - In rural areas, physicians are shortly supplied because burden for physicians working in hospitals has been increased in delivering high advanced medical technology. © 2012 Masanori Akiyama. All Rights Reserved 19

Percentage aged 65 or over (%) 40 Population 2010 35 30 Japan 25 China Indoneshia 20 Philippines Australia Malaysia 15 Republic of Korea Singapore 10 Thailand 5 0 Population Division of the Department of Economic and Social Affairs of the United Nations Secretariat, World Population Prospects: The 2008 Revision, http://esa.un.org/unpp, Wednesday, August 25, 2010; 4:28:54 AM. © 2012 Masanori Akiyama. All Rights Reserved 20

Population Decline in Japan Population Projections by age groups(2006) 140,000 120,000 100,000 80,000population(yhousand) over75 60,000 65 74 20 64 40,000 0 19 20,000 0 year Source: National Institute of Population and Social Security Research Population Projection for Japan: 2006-2050 © 2012 Masanori Akiyama. All Rights Reserved 21

Aging and Crisis in Healthcare System (2)3)Increasing Medical Cost - Absolute amount of cost grows; $350 billion in 2009 and 6.62% of GDP (2007) - Rapid increasing cost in recent years; growth rate impossible to cover in the near future - Financing ratio between out of pocket and public spending (including both insurance and the other public expenditure) is around 20% to 80%.4)Crisis in healthcare insurance - Extreme difficulty of National Health Insurance (managed by municipal governments for unemployed and self-employed including increasing retired, less paid, and poor health elders) - Much public fund has been used for covering the deficits of the National Health Insurance. The other insurance such as Government Managed Health Insurance, Union Managed Insurance and Mutual Aid Insurance also faces heavy deficits for increasing insured elders. In addition, budget restraint became more heavier than before. © 2012 Masanori Akiyama. All Rights Reserved 22

Increasing Healthcare Cost Total expenditure on health Health expenditure, public as % of gross domestic product in (% of total health expenditure) JAPAN 90 0.07 80 70 0.065 60 0.06 50 40 0.055 30 0.05 20 10 0.045 0 China Mexico Peru Japan Canada Indonesia Chile Korea, Rep. of Thailand Australia Singapore Russian Federation New Zealand Vietnam Papua New Guinea United States Philippines Malaysia 0.04 Brunei DarussalamSource:Estimates of National Medical Care Source: World Health Organization National HealthExpenditure(2007) and System of National Accounts(2007) Account database 2010 © 2012 Masanori Akiyama. All Rights Reserved 23

Direction for needed Reforms (1)efficient allocation of limited healthcare resources - Patients’ choice to hospitals and clinics is unlimited throughout the state but resources are not efficiently allocated such as personnel and material contributions needed for healthcare. For example, disparity in doctors, and hospitals/clinics, excessive purchase and use of medical devices, and unconnected healthcare between clinics and advanced hospitals, among clinics and among hospitals etc.From Hospital wards to Home (Average of hospital admission stay; about 17days) - One of the main reasons in inefficiency and the least used resource is medical information. To make meaningful use of medical information was not practical at all because of huge financial cost and much time for its introduction. However, recent IT progress has already become a promising solution to the problems on cost. - We lag behind in the statewide application of IT as a reasonably alternative resource because: - First, privacy concern is big about establishing core infrastructure of patient ID. - Second, trustworthiness of IT is insufficient and cost of initial investment is very high for IT introduction. - Third, hospitals and clinics are inactive for IT introduction. 17days. © 2012 Masanori Akiyama. All Rights Reserved 25

Direction for needed Reforms (2)• Recently, it is seriously discussed to introduce ID system. We find trend toward meaningful use of IT based on ID infrastructure enable to (1) keep tabs on patients, hospitals/clinics, allied health professional, and healthcare resources, (2) record all medical practices, and (3) deliver effectively all needed information for optimal resource allocation.• Positive Effects by Healthcare IT: 1)Sharing personal health information by hospitals and clinics for enhanced quality of care. 2)Researching comparative cost effectiveness of healthcare by all patient’s clinical data through realtime statistical procedure. 3)Using effectively resources by understanding allocation of resources and operating rates. 4)Managing optimally for hospitals and clinics• Total effect by use of IT in healthcare is uncertain because higher quality of healthcare causes increasing healthcare demand though the IT accomplishes enhanced quality and effective allocation of healthcare resources. However, cost introducing IT in healthcare must bring us the biggest benefit if it is optimally used. © 2012 Masanori Akiyama. All Rights Reserved 26

Positive Effects by Healthcare IT Quality Research Researching comparative Sharing personal health cost effectiveness ofinformation by hospitals healthcare by alland clinics for enhanced patient’s clinical data quality of care through realtime statistical procedure. Efficiency Optimality Using effectively Healthcare IT Managing optimally resources by for understanding hospitals and clinicsallocation of resources and operating rates. © 2012 Masanori Akiyama. All Rights Reserved 27

Agenda• Aging Issue and Crisis in Healthcare System• Healthcare System Reform in Japan – Average of hospital admission stay; about 17days to 7-10days, Shortening of 7 days• from Hospital wards to Home – Tele-healthcare• Insufficient trustworthiness of IT and Expensive cost of initial investment for IT introduction – Protect impersonator – Cloud computing© 2010 Masanori AKIYAMA. All Rights Reserved

From Hospital wards to HomeSharing personal health information by hospitals, clinics and home for enhanced quality of care.【Check point】 HOME• Vital signs • Body Temperature • Body Pressure • Pulse• Body Weight• Cooking and Eating• Excretion• Taking bath Hospital• Going out Ward【Features】• In real time• Sequential records Copyright © Policy Alternatives Research Institute

Niihama Medical Coop• We had a survey of system requirements in home-healthcare field with the cooperation of ―Niihama Medical Consumers Cooperative Society‖ (Niihama Medical Coop) which is one of home healthcare service facilities in Niihama city, Ehime prefecture in Japan.• Specifically, the hearing survey were conducted in patients home, group home, shared house, and clinic with nursing home care services.© 2010 Masanori AKIYAMA. All Rights Reserved 2012/2/6

Niihama Medical ConsumersCooperative Society• Niihama Medical Coop was founded in March 1974, as an organization for home medical care and home nursing care services.• It runs a business such as ambulatory rehabilitation, ambulatory care, home nursing care, group home, clinic for acupuncture and finger- pressure treatment, including the three clinics.• Currently, about 380 people engaged in business as doctors, nurses, careworkers, nursing staff, occupational therapists, physiotherapists.© 2010 Masanori AKIYAMA. All Rights Reserved 2012/2/6

Pedometer A pedometer is a device, usually portable and electronic or electromechanical, that counts each step a person takes by detecting the motion of the persons hips. Because the distance of each persons step varies, an informal calibration, performed by the user, is required if presentation of the distance covered in a unit of length (such as in kilometers or miles) is desired.• Used originally by sports and physical fitness enthusiasts, pedometers are now becoming popular as an everyday exercise measurer and motivator. Often worn on the belt and kept on all day, it can record how many steps the wearer has walked that day, and thus the kilometers or miles (distance = number of steps × step length). Some pedometers will also erroneously record movements other than walking, such as bending to tie ones shoes, or road bumps incurred while riding a vehicle, though the most advanced devices record fewer of these false steps. Step counters can give encouragement to compete with oneself in getting fit and losing weight. A total of 10,000 steps per day, equivalent to 5 miles (8.0 km), is recommended by some to be the benchmark for an active lifestyle, although this point is debated among experts. Step counters are being integrated into an increasing number of portable consumer electronic devices such as music players and mobile phones. © 2010 Masanori AKIYAMA. All Rights Reserved

Motion detector • A motion detector is a device for motion detection. That is, it is a device that contains a physical mechanism or electronic sensor that quantifies motion that can be either integrated with or connected to other devices that alert the user of the presence of a moving object within the field of view. • They form a vital component of comprehensive security systems, for both homes and businesses.Cell Phone (1) Motion sensor (2) Send Mail reacts when the person approaches. © 2010 Masanori AKIYAMA. All Rights Reserved

Automated acquisition at Home HOMECloud computing Infrastructure motion detector Servers Smart meter Cooking PC Taking Bath Excretion RFID RFID Going out Living © 2010 Masanori AKIYAMA. All Rights Reserved

Personal Health Record with NFCDaily record Date BP• Body Pressure (mmHg) – Time – Max – Min• Pulse• Body Weight• Pedometer BW(kg) – The number of steps• Drug administration© 2010 Masanori AKIYAMA. All Rights Reserved

Personal identification with SIM • SIM: Subscriber Identity Module Card – IMSI (International Mobile Subscriber Identity) • High personal authentication with high security has been secured by carrier; NTT DoCoMo, au and Softbank. • SIM card that can be obtained in Japan is usually a loan from the carrier, and when a contract is canceled, it is necessary to return it. • Personal identification with NFC VPN (Virtual Private Network) Device Tool ServerEX. ) Drug support EX. ) Smartphone, Tablet PCdevice, MEs NFC 3G Network SIM Internet SIM Contactless Card card authentication © 2010 Masanori AKIYAMA. All Rights Reserved

IMSI (International Mobile Subscriber Identity)• SIM cards are identified on their individual operator networks by a unique IMSI.• Mobile operators connect mobile phone calls and communicate with their market SIM cards using their IMSIs.• The format is: – The first 3 digits represent the Mobile Country Code (MCC). – The next 2 or 3 digits represent the mobile network code (MNC). 3-digit MNC codes are allowed by E.212 but are mainly used in the United States and Canada. – The next digits represent the mobile station identification number. Normally there will be 10 digits but would be fewer in the case of a 3-digit MNC or if national regulations indicate that the total length of the IMSI should be less than 15 digits.© 2010 Masanori AKIYAMA. All Rights Reserved

Authentication key (Ki)• The Ki is a 128-bit value used in authenticating the SIMs on the mobile network. Each SIM holds a unique Ki assigned to it by the operator during the personalization process. The Ki is also stored in a database (termed authentication center or AuC) on the carriers network.• The SIM card is designed not to allow the Ki to be obtained using the smart-card interface. Instead, the SIM card provides a function, Run GSM Algorithm, that allows the phone to pass data to the SIM card to be signed with the Ki. This, by design, makes usage of the SIM card mandatory unless the Ki can be extracted from the SIM card, or the carrier is willing to reveal the Ki.• In practice, the GSM cryptographic algorithm for computing SRES_2 from the Ki has certain vulnerabilities that can allow the extraction of the Ki from a SIM card and the making of a duplicate SIM card.© 2010 Masanori AKIYAMA. All Rights Reserved

Why Japan’s Cellphones Haven’t Gone Global Japan’s cellphones are like the endemic species that Darwin encountered on the Galápagos Islands — fantastically evolved and divergent from their mainland cousins THE OSAIFU-KEITAI SYSTEM (LITERAL TRANSLATION: "WALLET-PHONE")© 2010 Masanori AKIYAMA. All Rights Reserved

Suica is a rechargeable contactless smart card used as a fare card on train lines in Japan. • Launched in November 2001, the card is usable currently in the Kantō region, at JR East. The card can also be used interchangeably with JR Wests, and also with JR Central starting from spring of 2008, JR Kyushu starting from spring of 2010. • The card is also increasingly being accepted as a form of electronic money for purchases at stores and kiosks, especially within train stations. As of October 2009, 30.01 million Suica cards are in circulation.Since Suica is completely interchangeable with thePasmo card (see for the complete listing of companiesand lines that accept Suica) in the greater Tokyoarea, it is supported on virtually anytrain, tramway, and bus system (excluding variouslimited and shinkansen trains, as well as a few localbuses as the system is still in the process of beingextended to all routes). © 2010 Masanori AKIYAMA. All Rights Reserved

Mobile FeliCa• Mobile FeliCa is a modification of FeliCa for use in mobile phones by FeliCa Networks, a subsidiary company of both NTT DoCoMo and Sony. DoCoMo has developed a wallet phone concept based on Mobile.• The Osaifu-Keitai system (literal translation: "wallet-phone") was developed by NTT DoCoMo, and introduced in July 2004 and later licensed to Vodafone and au, which introduced the product in their own mobile phone ranges under the same name.• FeliCa, developed by Sony, is the de facto standard technology used for Japanese smart cards. Many of these cards accept Osaifu-Keitai (Mobile FeliCa) system as well, or plan to accept it in future. Osaifu- Keitai can provide more convenient services than plastic FeliCa cards. For instance, it can automatically recharge itself via the Internet, or provide the latest information.• It can also be used as a ticket for an airplane or an event, by downloading an electronic ticket. Unlike plastic cards, a single Osaifu- Keitai phone may accept multiple applications, each equivalent to different cards.© 2010 Masanori AKIYAMA. All Rights Reserved

FeliCa is a contactless RFID smart cardsystem from Sony in Japan,• primarily used in electronic money cards. The name stands for Felicity Card. First utilized in the Octopus card system in Hong Kong, the technology is used in a variety of cards also in countries such as Singapore, Japan and the United States.• FeliCas encryption key is dynamically generated each time mutual authentication is performed, preventing fraud such as impersonation.• FeliCa is externally powered, i.e. it does not need a battery to operate. The card uses power supplied from the special FeliCa card reader when the card comes in range. When the data transfer is complete, the reader will stop the supply of power.• FeliCa was proposed for ISO/IEC 14443 Type C but was rejected. However, ISO/IEC 18092 (Near Field Communication) uses some similar modulation methods. It uses Manchester coding at 212 kbit/s in the 13.56 MHz range. A proximity of 10 centimeters or less is required for communication.© 2010 Masanori AKIYAMA. All Rights Reserved

Conclusion• Our future challenge is to validate the effectiveness and impact of this system and clarify the features for improvement.• One of requirements for smart phone application is the simple interface design which is easier enough for all of care-workers and elderly people, that there is no keyboard only to touch the panel for operation.• The user-familiar interface is needed to be used by not only care-workers but also patient’s families.© 2010 Masanori AKIYAMA. All Rights Reserved

Outcome by applying the system in homehealth• take advantage of that objective information for evidence-based management and quality control of home care service.• Systematic effect can be the practical use of aggregated information to properly evaluate the care services.• The system helps to make an effective use of information stored in the system for appropriate assessment according to realistically job analysis, by aggregating and managing information that was recorded in the notebook traditionally.• Information recorded in real time can be used as an objective data of patients and users of home care, it is possible to accurately grasp the reality of health care workers also. Revealed by the current situation, it is possible to make the quality of nursing care.• You can visualize the process of care services, conduct business analysis. By objective evidence-based analysis is expected to make use of the management of regional alliance between hospitals and nursing homes.•© 2010 Masanori AKIYAMA. All Rights Reserved

Outcome by applying the system inhome health• Secondly, the whole data can be useful for medical practice collected by the system because it helps to understand the long-term changes of the patient condition.• Information recorded in real time data can be used as an objective data; it is possible to accurately grasp the reality of patients and users of home health care. It can be used effectively to better medical practice, utilizing the information stored as a database can show the aging of the patient to understand for a long time about 10 to 20 years.• Next challenge is to verify the effectiveness of these two points above, and to make further investigation necessary features.© 2010 Masanori AKIYAMA. All Rights Reserved

Thank you for your attention.Any Questions?• Imagine !• What kind of system do you want, if your son or daughter were a patient? E-mail: makiyama@pp.u-tokyo.ac.jp poas@mit.edu© 2010 Masanori AKIYAMA. All Rights Reserved

Technology Presentations NFC in sleep Pill monitoring / Smart NFC monitoring Smart packaging sensorsSandra Eliott, Director, Hajo Hanse, CTO, John Peeters, CEO,Meridian Health / IMPak Qolpac Gentag #MITFORUM #NFCClusterBos

US Market Opportunity – Sleep Assessment Total Population =317,641,000 Demographic Target* =132,475,000 Sleeping Disorder Dx. = 18,547,900 Potential = 113,927,100 *(M/F 20-35 & M/F 40-55)Confidential information

Sleep Pattern Monitoring Card • Monitoring sleep activity to give the user feedback on how well he/she is sleeping; give hints for improvements • Time to sleep, REM sleep periods etc can be monitored – analysis done in mobile app – Analysis tool yet to be understood and developed • Features (tbd) – Data display as actigraph – Start / stop button + auto stop after e.g.12 hrs (battery saving) – Programmable to record data each night for a certain period • We are discussing details with our partner Meridian Health to get the functionality & app as attractive and relevant as possibleConfidential information

Key Healthcare System Statistics95 Convenient locations$1.6 Billion in Annual system Revenues11,800 Team Members2,100 Physicians on Staff Partner Companies $300+ million in Annual Revenue Post Acute Care: 5 facilities, 728 beds At Home Nursing, Hospice, & Rehab: Serving all of Central New Jersey Ambulatory Care: 12 facilities Primary Care Network: 20+ physician practices Ambulance/Medical transport: 100+ vehicles Occupational Health: 6 centers Rehabilitation and Fitness: 9 facilities, 2 inpatient facilities Behavioral Health: 5 outpatient, 2 inpatient facilities

From Partnership to Product Distribution TechnologyValue Add ($) Source: ―The Smile Curve‖, Stan Shih, Acer Computers Time Production

Our Technology PartnerAbout Cypak•Founded 1999•20 Engineers•Personal connected health market•Innovative technology platforms enable principal products ina range of applications for high-volume markets: • Intelligent, low cost, consumable medication packaging • Wireless interconnectivity solutions•Proven technology solutions•Key strategic position with a patented product portfolio•Authority on industry standards (Continua, etc.)•Strong customer, partner and advisory network: • packaging, devices, pc managers, system integrators, healthcare providers .

iMPak Health NFC – Based Product Lines .

Sample Post Discharge Home Management Kits COPDMultiple COPD tools bundled together for a more complete picture of an individual’s health.Sample Kits include: Pulse Ox Card, Spirometry Card, COPD Symptom Journal,Medication Manager, and Educational Booklet .

Sample Post Discharge Home Management Kits Adult AsthmaMultiple Asthma tools bundled together for a more complete picture of an individual’shealth. Sample Kits include: Pulse Ox Card, Spirometry Card, SleepTrak, Asthma symptomJournal, and Educational Booklet .

NFC Enabled Medication Manager/Solution Features:•Targets the challenge of non-adherence & compliance•Tracks medication adherence withreal time data•Reminds patients to take medicationincreasing patient compliance•Designed in convenient, pocket-worthy form factor for easy travel andmobility .

Visit our Website to Explore a Different Solutions www.impakhealth.com/health-solutions .Click on the most appropriate link to view some sample use cases for your industry: Insurance Company Hospital / Health System Pharmacy Benefit Management Pharmaceutical Company Employer Benefits Management Retail Pharmacy

W.H.O Recommendations• “Increasing the effectiveness of adherence interventions may have a far greater impact on the health of the population than any improvement in specific medical treatments”• "Adherence is a dynamic process that needs to be followed up“• Adherence is an important modifier of health system effectiveness Property of Qolpac - All Rights Reserved - Confidential

Mission Statement “To Create an easy to use environment thathelps people to improve their quality of life byproviding knowledge, information and supportby the means of E-communicative packaging.” Property of Qolpac - All Rights Reserved - Confidential

Healtheness Schedules• Schedule Intake, Gluco & Blood Pressure • User profile & Social media support• Create timeslots, Alerts & Reminders • Order Refills• Register scheduled & Incidental Events • NFC support for easy event Registration• Link events to timeslots • I.C.E Support via NFC Property of Qolpac - All Rights Reserved - Confidential

Healtheness Schedules• Health community• Positive enforcement• Personal Medical Dossier• Health Summery • Extensive health overview • Cross-reference outcomes • Graphs and Statistics • Advice and Recommendations Property of Qolpac - All Rights Reserved - Confidential

OtCMtm-Tag• Auto launch Application • Register intake by tap• Can Store Medication name and • Various form factors Prescription • Suited for all kinds of packaging• Can Launch url to download application• Allows Branding Property of Qolpac - All Rights Reserved - Confidential

OtCMtm-Firefly• All parts that can touch medication are made of pharma grades PP and TPE• Electronics, batteries and metal parts cannot touch the medication• Has custom child resistance mechanism in dispenser• Records date and time of each open event in memory• Records Removal events event in memory• Readable with NFC enabled mobile phone or EventTaker (NFC reader on PC)• Compatible with standard Rexam bottles Property of Qolpac - All Rights Reserved - Confidential

OtCMtm-Blixtertm• Supports any blister package by using self-adhesive blister labels• Records the Date, Time & Cavity ID of a removed pill• Compatible with Qolpac mobile application interface• Standard up to 28 cavity blister packages (more cavities are optional)• Readable with NFC enabled mobile phone or EventTaker (NFC reader on PC)• Available in 2 models: Reusable and disposable Blixtertm-Clip Blixtertm-STUMO 4 Blixtertm-STUMO 5 Blixtertm-STUMO 6 GOAL (current development) Printed circuitry Printed circuitry Glued Ultra Thin Electronic Glued single Chip Components Electronic Components (Outside) Electronic Capacitor Printed Carbon components Capacitor in Casing Property of Qolpac - All Rights Reserved - Confidential

NFC SENSORS FORPERSONALIZED HEALTH MIT PRESENTATION GENTAG, INC. 3299 K Street, Suite 100 Washington, DC 20007 FEBRUARY 6, 2012

NFC Diagnostic Skin Patches (Over 20 Major Markets)10 ISSUED PATENTS, 61 PENDING 83

Custom NFC Sensors: Cystic Fibrosis Example INDIVIDUALIZING MEDICINE RECENT BOSTON SUCCESS STORY (VERTEX): G551D MUTATION - 1 DRUG 1,200 patients in USA 84

Disposable NFC Biomarker & Genetic Tests for Consumers APPLICATIONS INCLUDE:  DRUG TOXICITY  PATHOGENS  ALLERGENS  OTC TESTS  CANCER DETECTION  BIOMARKERShttp://siliconinvestor.advfn.com/readmsg.aspx?msgid=27035270 85

Revolutionizing Personal Diagnostics with NFC THREE GOLDEN RULES  SIMPLE TO USE (PAINLESS DIABETES PATCHES)  LOW COST DEPLOYMENT (SENSORS AND PHONES)  INDIVIDUALIZED SENSORS (1 MUTATION – 1 SENSOR – 1 APP) 86

Moderator for Panel Discussion Joe Ternullo, JD, MPH Director, Partners Center for Connected Health #MITFORUM#NFCClusterBos

Panel DiscussionNick Holland, Charles Walton, Gagan Puranik,Senior Analyst COO Assoc. Director #MITFORUM #NFCClusterBos

Thank you to tonight’s sponsor Reception 8:30pm – 9:30 pm Catalyst Restaurant, 300 Technology Square 5 minute walk! Right on Vassar street to Main Street, left on Main for one block, cross the street to Catalyst #MITFORUM#NFCClusterBos

NFC In SmartphonesTransforms Healthcare February 6, 2012 6:00-8:30pm Sponsored by: #MITFORUM#NFCClusterBos

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