Multiple Alleles, Sickle Cell Evolution, Pedigrees, & Sex Linkage

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Multiple Alleles, Sickle Cell Evolution, Pedigrees, & Sex Linkage

  1. 1. As a cell prepares to divide the DNA becomes condensed into compact structures called chromosomes (chromo = colored, somes = bodies) ‏ Offspring get DNA from parents by inheriting chromosomes!!!
  2. 3. In humans, each body cell has 46 chromosomes in 2 sets (23 pairs) ‏ One set of chromosomes come from the mother and one set comes from the father
  3. 4. There can be more than two alleles for a gene! Human Blood Type has three alleles: A, B, and i AB are codominant, while i is recessive to both A and B Genotype Phenotype AA A Ai A BB B Bi B ii O AB AB More Complexity
  4. 5. Mutations: Sickle-Cell Anemia
  5. 6. If a mutation occurs in a sperm or egg, it may be transmitted to offspring If that mutation has a negative effect on the phenotype of an organism, the mutant condition is referred to as a genetic disorder (hereditary disease) ‏ BUT, not all mutations are harmful!!! Some mutations may make an individual better adapted to its environment, improving its chances for survival
  6. 7. Sickle Cell Anemia Blog Post
  7. 9. How to Solve Pedigree Problems
  8. 11. Sex-linkage – disorders or characteristics are found on the sex chromosomes

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