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Multiple Alleles, Sickle Cell Evolution, Pedigrees, & Sex Linkage
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Multiple Alleles, Sickle Cell Evolution, Pedigrees, & Sex Linkage

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Transcript

  • 1. As a cell prepares to divide the DNA becomes condensed into compact structures called chromosomes (chromo = colored, somes = bodies) ‏ Offspring get DNA from parents by inheriting chromosomes!!!
  • 2.  
  • 3. In humans, each body cell has 46 chromosomes in 2 sets (23 pairs) ‏ One set of chromosomes come from the mother and one set comes from the father
  • 4. There can be more than two alleles for a gene! Human Blood Type has three alleles: A, B, and i AB are codominant, while i is recessive to both A and B Genotype Phenotype AA A Ai A BB B Bi B ii O AB AB More Complexity
  • 5. Mutations: Sickle-Cell Anemia
  • 6. If a mutation occurs in a sperm or egg, it may be transmitted to offspring If that mutation has a negative effect on the phenotype of an organism, the mutant condition is referred to as a genetic disorder (hereditary disease) ‏ BUT, not all mutations are harmful!!! Some mutations may make an individual better adapted to its environment, improving its chances for survival
  • 7. Sickle Cell Anemia Blog Post
  • 8.  
  • 9. How to Solve Pedigree Problems
  • 10.  
  • 11. Sex-linkage – disorders or characteristics are found on the sex chromosomes