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Contenido de The New England Journal of Medicine.

Contenido de The New England Journal of Medicine.

Published in: Health & Medicine

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  • 1. Original Article Pneumonia and Respiratory Failure from Swine-Origin Influenza A (H1N1) in Mexico Rogelio Perez-Padilla, M.D., Daniela de la Rosa-Zamboni, M.D., Samuel Ponce de Leon, M.D., Mauricio Hernandez, M.D., Francisco Quiñones-Falconi, M.D., Edgar Bautista, M.D., Alejandra Ramirez-Venegas, M.D., Jorge Rojas-Serrano, M.D., Christopher E. Ormsby, M.Sc., Ariel Corrales, M.D., Anjarath Higuera, M.D., Edgar Mondragon, M.D., Jose Angel Cordova-Villalobos, M.D., for the INER Working Group on Influenza N Engl J Med Volume 361(7):680-689 August 13, 2009
  • 2.
    • This case series describes the first 18 patients hospitalized with infection with novel swine-origin influenza A (H1N1) virus (S-OIV) from March 24 through April 24, 2009, in Mexico City
    • More than half the patients were between 13 and 47 years of age, and most had been healthy previously
    • Respiratory distress requiring intubation and mechanical ventilation developed in 10 patients; 7 patients died
    • There were 22 secondary infections among health care workers, none of which required hospitalization
    Study Overview
  • 3. Emergency Room Consultations for Pneumonia or Respiratory Infection, Including Influenza-like Illness, at the National Institute of Respiratory Diseases of Mexico Perez-Padilla R et al. N Engl J Med 2009;361:680-689
  • 4. Characteristics of the 18 Study Patients Who Had Confirmed Infection with Novel Swine-Origin Influenza A (H1N1) Virus Perez-Padilla R et al. N Engl J Med 2009;361:680-689
  • 5. Clinical Courses of the Study Patients Perez-Padilla R et al. N Engl J Med 2009;361:680-689
  • 6. Survival and Death among the 18 Study Patients Who Had Confirmed Infection with Novel Swine-Origin Influenza A (H1N1) Virus Perez-Padilla R et al. N Engl J Med 2009;361:680-689
  • 7. Initial Radiograph of the Lung and Lung-Tissue Sample from Patient 3 Perez-Padilla R et al. N Engl J Med 2009;361:680-689
  • 8.
    • S-OIV infection can cause severe illness, the acute respiratory distress syndrome, and death in previously healthy persons who are young to middle-aged
    • None of the secondary infections among health care workers were severe
    Conclusion

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