Tuberculous chancre is asymptomatic ulcerated nodule covered by crust
The ulcer has the characteristic of tuberculous ulcer .
Primary tuberculosis of the skin
Primary inoculation tuberculosis A large, ulcerated nodule at the site of M.tuberculosis inoculation on the right thigh associated with inguinal lymphadenopathy. The erythematous papules on the left forearm occurred at the site of tuberculin testing.
It is rare haematogenous dissemnated of tuberculosis .
The very rare skin eruption consist of generalized erythematous papules and pustule in an immuno-suppressed person
Miliary tuberculosis of the skin
Occur as an exogenous inculation of bacilli in a person with high degree of immunity .
Age : usually children and also in adult
Site of trauma
Extremities and buttocks
A verrucous indurated plaque with fissure and active inflammatory border .
Tuberculosis verrucosa cutis
Tuberculosis verrucosa cutis Crusted and hyperkeratotic plaque arising at the site of inoculation in an individual previously infected with M. tuberculosis . There is no associated lymphadenopathy
The most common form of skin tuberculosis
Site : head and neck especially around the nose .
- patches :
contained deep seated nodules
Scarring is evident and could be mutilating
Course : chronic with healing of center by scarring and extension of the lesion at the periphery .
Lupus vulgaris Reddish-brown plaque, which on diascopy exhibits the diagnostic yellow-brown apple-jelly color
Types of lupus vulgaris :
Hypertrophic or verrucus type.
Atrophic type .
Ulcerative type .
Tumor like type .
Development of squamous cell carcinoma
Destruction of the nose
Scrofuloderma Scrofuloderma represent a direct extension from underlying focus (bone or LN) to the skin. Site : _ Neck _Chest Morphology : -An asymptomatic reddish swelling which breaks down to form sinuses, fistulate or tuberculuos ulcers. -Characteristic caseous materil discharges from lesions.
Tuberculosis Cutis Orificialis
Tuberculoisis cutis orificialis occurs on or around orifices of patients with low immunity and internal tuberculosis.
-On and around orifices (mouth,anus,…)
-Tuberculous ulcer with a granulating base.
Site: widely distributed.
Morphology: papules with central necrosis.
Response to anti-tuberculous therapy: good.
Response to anti- tuberculosis therapy: good.
Erythema Induratum ofBazin
Age&sex: young adult woman
Site: lower leg( posterior aspect).
-Deep-seated subcutaneous nodule.
-Heals with atrophic scar.
Histopathology of Cutaneous Tuberculosis
-Dermal tuberculous tubercles formed of central caseation ( may be absent) and surrounded by epithelioid cells , giant cells, monocytes and lymphocytes .
Treatment of Tuberculosis
Good nutrition .
Search for underlying focus
Combination of more than one anti-tuberculous drug