Schizo obessive disorder
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Schizo obessive disorder

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    Schizo obessive disorder Schizo obessive disorder Presentation Transcript

    • Schizo-obsessive disorder ? A new subtype of schizophrenia Dr J Romain Dr Yagoub
    • Possible definition
      • Patients who have OCD and schizophrenia and whose obsessions and compulsions are unrelated to the content of their psychosis.
      • Controversy centres on whether there is a continuum or overlap in psychopathology between these entities that some authors have called "schizo-obsessive disorder."
    • Why do we care?
      • Schizo-obsessive patients have a more chronic course, a greater frequency of social and occupational impairment, and show poor treatment response and a poor long-term outcome.
    • Research
      • A study by Michael Y. Hwang, M.D in journal of neuropsychiatry and clinical neurosciences 12:91-94, Feb 2000
      • A pilot blind controlled study, 20pts
      • Compared characteristics of obsessive-compulsive (OC) schizophrenic patients and a matched non-OC schizophrenic control group
    • Results- Schizo-obessive group
      • Significantly longer periods of hospitalisation
      • They took more adjunctive medications such as benzodiazepines and antidepressants
      • They had a poorer clinical course with lower levels of functioning, especially in terms of "self-care" and "social competency”
    • Results for Schizo-obsessive group
      • Higher rate of negative symptoms
      • Higher level of general psychopathology using the Wisconsin Card Sorting Test (WCST) and MMSE.
      • No difference in positive symptoms, anergia, depression or thought disturbance factors.
    • Summary of Study
      • Findings indicate that schizo-obsessive patients may possess a unique clinical and neuropsychological profile within the schizophrenic spectrum
    • Possible treatment Regimes
      • Treatment with serotonin reuptake blockers, added to a neuroleptic, is found to be efficacious in the treatment of obsessions and compulsions and to improve overall schizophrenic symptoms.
    • Discussion
      • Both patients clearly exhibit hoarding as their obsessional symptom
      • Hoarding is being considered as a part of OC spectrum in its own right for DSM-V
      • Recent literature suggests that the core symptoms, associated features, and neurobiological abnormalities of hoarding differ from OCD.
    • Other Possible Diagnoses
      • OC Schizophrenia?
      • Compulsive hoarding syndrome with some psychotic symptoms?
      • Questions?