Lecture 4 The Bacterial World

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Lecture 4 The Bacterial World

  1. 1. Online bioscience course for grades 6-12 Fall 2009 bio 1.0
  2. 2. Class mechanics… <ul><li>Attend the online Office Hour on Tuesdays at 3 PM </li></ul><ul><li>via tokbox-Discuss previous week’s video lecture </li></ul><ul><li>Online video lecture e-mailed every Wednesday-view </li></ul><ul><li>lecture and prepare to discuss the following Tuesday </li></ul><ul><li>Comment on video lecture using website discussion </li></ul><ul><li>board </li></ul><ul><li>Online Final Exam given 12/9/2009 </li></ul>bio 1.0
  3. 3. Lecture 4: The bacterial world bio 1.0
  4. 4. Take Homes: <ul><li>Bacteria have highly organized structures </li></ul><ul><li>II. The genome of bacteria </li></ul><ul><li>III. Bacterial cell movement </li></ul><ul><li>IV. Bacterial cell growth and metabolism </li></ul><ul><li>V. Bacterial films and the “microbiome” </li></ul>bio 1.0
  5. 5. The basic structure of a bacterium (prokaryote): bio 1.0
  6. 6. Bacterial surface types: bio 1.0
  7. 7. Diffusion: bio 1.0
  8. 8. Active diffusion: bio 1.0
  9. 9. Bacterial types: bio 1.0
  10. 10. Bacterial conjugation: http:// en.wikipedia.org/wiki/Bacterial_conjugation bio 1.0
  11. 11. Transformation: http://en.wikipedia.org/wiki/Transformation_%28genetics%29 bio 1.0
  12. 12. The pGLO plasmid: http:// en.wikipedia.org/wiki/PGLO bio 1.0
  13. 13. Bacteria use their flagella to move: bio 1.0
  14. 14. The structure, assembly and function of the flagellum: http:// www.youtube.com/watch?v =Ey7Emmddf7Y bio 1.0
  15. 15. Bacterial genome: bio 1.0
  16. 16. Bacterial genome-”gene music”: http:// www.youtube.com/watch?v =G8ZAGi4ZlFI bio 1.0
  17. 17. Take Home I From their cell membranes and flagella down to the organization and replication of their DNA bacteria are highly organized and efficient structurally… Bacteria have highly organized structures bio 1.0
  18. 18. The flagellum “control circuit”: bio 1.0
  19. 19. In bacteria, genes that are part of a “circuit” often are grouped together in the genome: bio 1.0
  20. 20. The trp operon: http:// www.youtube.com/watch?v =8aAYtMa3GFU bio 1.0
  21. 21. Take Home II The DNA genome of bacteria is very highly organized and efficient… The genome of bacteria bio 1.0
  22. 22. Bacterial growth: http:// www.youtube.com/watch?v = gEwzDydciWc bio 1.0
  23. 23. DNA replication: bio 1.0
  24. 24. Bacterial motility: http:// www.youtube.com/watch?v =zlFRJftA2bU bio 1.0
  25. 25. Bacterial motion and disease: http:// www.youtube.com/watch?v =YZIg8FL4alA bio 1.0
  26. 26. Take Home III The mechanisms and controls of movement in bacteria are highly varied and play a role in disease… Bacterial cell movement bio 1.0
  27. 27. In prokaryotes, chromosomal DNA replication starts from a single point (an ori ) and proceeds bi-directionally… bio 1.0
  28. 28. Semi-conservative DNA replication: http://www.dnatube.com/video/3028/Semiconservative-Replication bio 1.0
  29. 29. Glycolysis and fermentation: http:// www.youtube.com/watch?v =UmfYnjHs8nk bio 1.0
  30. 30. Take Home IV Bacterial growth and metabolic pathways are well defined processes… Bacterial cell growth and metabolism bio 1.0
  31. 31. Biofilms I: http:// en.wikipedia.org/wiki/Biofilms bio 1.0
  32. 32. Biofilms II: 5 stages of biofilm development. Stage 1, initial attachment; stage 2, irreversible attachment; stage 3, maturation I; stage 4, maturation II; stage 5, dispersion. Each stage of development in the diagram is paired with a photomicrograph of a developing P. aeruginosa biofilm. All photomicrographs are shown to same scale. bio 1.0
  33. 33. Biofilms III: Stromatolites, proof of Life's Origin http:// www.youtube.com/watch?v =4opsN_iQdEs bio 1.0
  34. 34. The human microbiome: http:// www.youtube.com/watch?v = zzxEaGjXFZw bio 1.0
  35. 35. Take Home V Bacteria can form multicellular structures known as biofilms and also form complex symbiotic relation ships within higher organisms such as humans… Bacterial films and the “microbiome” bio 1.0
  36. 36. Next Week: Higher cells How higher cells are structured and how they function… bio 1.0
  37. 37. instructor Mark E Minie PhD [email_address] bio 1.0

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