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Cholera & bangladesh
Cholera & bangladesh
Cholera & bangladesh
Cholera & bangladesh
Cholera & bangladesh
Cholera & bangladesh
Cholera & bangladesh
Cholera & bangladesh
Cholera & bangladesh
Cholera & bangladesh
Cholera & bangladesh
Cholera & bangladesh
Cholera & bangladesh
Cholera & bangladesh
Cholera & bangladesh
Cholera & bangladesh
Cholera & bangladesh
Cholera & bangladesh
Cholera & bangladesh
Cholera & bangladesh
Cholera & bangladesh
Cholera & bangladesh
Cholera & bangladesh
Cholera & bangladesh
Cholera & bangladesh
Cholera & bangladesh
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Cholera & bangladesh

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  • 1. Sujit Dey B.Sc, MTU.S. Embassy-DhakaBangladesh
  • 2. One of the Youngest Victims
  • 3. Cause*Bacterium Vibrio cholerae*This bacteria produces enterotoxin known as cholera toxin
  • 4. Biochemical Properties• Gram –negative bacteria• Straight or curved rods• Fermentative and oxidative in metabolism• Oxidase positive
  • 5. PathogenesisTransmitted by the fecal-oral route(Specially Contaminated Water)Adheres and colonizes to the small bowelSecretes the cholerae enterotoxin (CT)
  • 6. Symptoms• Massive Watery Diarrhea• Muscle and Stomach Cramp• Vomiting• FeverLater Stage Symptom:* Rice Water Stool
  • 7. Diagnosis• Rice Water Stool (Severe watery diarrhea)• Dehydration• Shock• Loss of urine production
  • 8. Laboratory DiagnosisA wet mount of liquid stool can be examined microscopically using “Dark Field Condenser”Cholera Bacteria will look like shooting stars
  • 9. “Dark Field Condenser”
  • 10. Stool CultureUsed TTGA (Taurocholate Tellurite Gelatin Agar) plates for growth of VibrioA MacConkey and SS plate is used for the growth of other organism-if present
  • 11. Dept. of Microbiology
  • 12. When TTGA Positive Confirmed by testing withCholera Antisera
  • 13. Cholera Serotypes HikozimaOgawa Inaba (Not found in Bangladesh) Ogawa biotype Classical Eltor (Not found in Bangladesh)
  • 14. SensitivityNotice the Difference
  • 15. Ogawa: Tetracycline Resistant Inaba: Tetracycline Sensitive(Sensitivity or resistance is not 100%, there is some variations)
  • 16. Global Scale
  • 17. Treatment• Essentially replacing the lost fluid and electrolytes• Antibiotics
  • 18. ICDDR,B Treatment
  • 19. Treatment
  • 20. Prevention• Ensuring personal Hygiene• Treated Water (Boiling and other treatment)• Hand Washing is important
  • 21. Prevention• Vaccination if available
  • 22. Thank You

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