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  • 1. MedITEX  IVF  and  MedITEX  Scheduler  Release  Notes      Version  1.3.0.0  Features      1.) General  features:     a. An  automatic  text  completion  feature  was  integrated.  In  many  text  fields  the  program  will  offer  entries   previously   entered   in   that   field,   filtered   according   to   typed   keys.   Additionally,   in   note   fields   it   is   possible   now   to   use   the   key   combination   Ctrl+Space   to   open   a   drop   down   list   with   all   previously   entered  texts,  filtered  also  according  to  typed  keys.     b. The   new   interface   with   “Labotect”   incubators   allows   the   automatic   import   of   incubator   protocols   in   MedITEX  IVF.      2.) Semen  analysis  (spermiogram):     a. It  is  now  possible  to  add  videos  and  various  documents  in   spermiogram.       b. A   dozen   of   new   fields   considering   analysis   and   morphology  of  the  sperms  have  been  added.      3.) Cryo  storage:     a. Cryo   storage   mask   was   extended   with   a   number   of   new   fields,   including   the   freezing   and   thawing   methods  and  additional  straw  colour.      4.) Home  screen:     a. Among  other  important  data  from  the  medical  history,  the   name  of  attending  physician  is  also  displayed.       b. Therapies  (cycles)  are  per  default  ordered  by  start  date.      5.) Planned  cycles:     a. In   therapy   planning   and   in   the   form   for   creating   new   therapies   it   is   now   possible   to   choose   a   treatment  protocol.     b. The  new  functionality  in  calendar  area  offers  the  possibility  to  save  the  complete  current  planning  as  a   template  for  future  use.  In  this  way,  using  the  button  “Template”  in  the  lower  left  corner,  the  current   plan   for   drugs   administration,   lab   and   ultrasound   examinations,   and   other   important   events   can   be   saved  in  one  cycle  and  easily  restored  in  another,  without  the  need  to  enter  all  the  data  again.         Page  1  of  22  
  • 2.                   c. After  creating  an  active  cycle  out  of  planned  therapy,  the  days  with  planned  laboratory  and  ultrasound   tests  will  be  marked  with  a  small  red  triangle  and  a  hint  “Examination  planned”.      6.) Cycle  overview  and  lutheal  phase:     a. Between  Hormone  and  Follicle  U.S.  the  new  rows  "Ultrasound"   and  "Examination"  were  inserted.  In  this  way  it  is  also  possible   to   enter   ultrasound   data   not   directly   related   to   follicle   examination.   If   an   image   is   available,   a   camera   icon   will   be   shown.   If   no   image   is   available   the   green   check   symbol   is   displayed.       b. In  ultrasound  form  it  is  possible  to  enter  the  physician  and  the   note,  and  to  attach  videos.       c. Physician   name,   note   and   ultrasound   preview   image   will   be   shown  in  a  hint,  if  the  mouse  stands  over  a  cell  with  a  camera   or  check  symbol.     Page  2  of  22  
  • 3. d. The  parameters  shown  in  the  overview  are  no  more  constrained  to  5  most  important  hormones.  From   now   on   it   is   possible   to   select   any   laboratory   parameter   for   display   in   the   cycle   overview   (see   point   10.b.ii).   The   parameters   are   grouped   automatically   into   groups   that   can   be   collapsed   and   expanded   at   will.        7.) Culture:     a. New  embryo  stadium  is  introduced:  “Start  of  cavitation”,  between  “Morula”  and  “Early  blastocyst”.       b. Besides  images,  it  is  now  possible  to  attach  videos  also.     c. For   each   oocyte/embryo   it   is   now   possible   to   enter   the   incubator   data,   either   over   the   context   menu   in   the   graphical   culture   representation,   or   in   the   development   form   for   each   embryo.   Information   about   incubators  used  in  the  clinic  can  be  defined  in   system  settings.        8.) Transfer:    The  development  stage  of  the  embryo  is  now  also  explicitly  shown:  “4  cells”,  “8  cells”  etc.      9.) Patient  data:    Two  new  fields  have  been  added:  “Birth  place”  and  “State".      10.) System  settings:     a. Grouping   of   letters:   in   the   administration   of   report   editor   letters   (SettingsàSystemàReport   editoràAdministrate  letters)  it  is  now  possible  to  define  a  “subgroup”  for  each  letter.  It  is  enough  to   write  the  group  name  in  the  field  “Group”,  or  to  select  one  of  the  existing  ones.                                             Page  3  of  22  
  • 4. The  letters  belonging  to  the  same  group  will  be  grouped  in  a  submenu  item  with  the  group  name.                 b. In  the    "lab"  tabsheet  it  is  now  possible  for  each  parameter  to  define  the  following:       i. If  a  parameter  should  appear  in  the  home  screen,  in  the  list  of  lab  tests.  The  result  of  the  most   recent  examination  will  be  shown.   ii. If   a   parameter   should   appear   in   the   calendar   of   therapy   overview   (as   described   in   the   point   6.d).   iii. If   a   parameter   should   be   offered   in   the   mask   for   fast   entry   of   more   parameters   at   once,   “Multiple  entry  in  laboratory  values”,  in  laboratory  diagnostics.                                           iv. Validity  period  for  each  parameter.  The  choices  offered  are  "unlimited",  "2  weeks",  "1  month",   "3  months",  "6  months"  and  "12  months".  If  the  validity  period  of  a  parameter  shown  in  the   lab  diagnostics  or  in  the  home  screen  has  expired,  or  the  parameter  has  not  been  examined  at   all,  the  parameter  row  will  be  marked  in  red.                                     Page  4  of  22  
  • 5. c. The   item   list   of   the   field   “Group”   for   lab   parameters   can   now   be   freely   extended   by   user   defined   groups,  in  “SystemàSettingsàSystem  tablesàLaboratory  parameter:  group”.     d. In   the   clinic   data,   it   is  now   possible   to   enter   the   clinic’s   state/province.   Provinces   can   be   added/edited   in  “SystemàSettingsàSystem  tablesàProvinces”.     e. Different  personal  customizations  can  be  saved  per  user,  in  the  “Edit  staff  data"  form  of  the   staff  area.   So  it  is  possible  to  set  the  visibility  of  “up/down”  buttons  in  the  table  representation  of  culture,  or  to   define   the   size   of   the   preview   images   in   hints   (embryo   images   in   culture   and   ultrasound   images   in   therapy  overview).     f. The  basis  for  the  automatic  calculation  of  the  current  pregnancy  week,  abort  week  and  birth  week  can   be  set  as     -­‐ Fertilization  day  (default),  or     -­‐ Reference  date  (Last  menstrual  period  or  treatment  start  date).      11.)  System  settings  –  interface  to  MedITEX  Scheduler:    Automatic   generation   of   appointment   proposals   in   MedITEX   IVF   (possible   only   in   conjunction   with   the  MedITEX  Scheduler  -­‐  see  also  feature  point  15):    In   “System   settingsàSystemàInterfacesàMedITEX   Scheduler”   you   will   find   a   list   of   certain   events,   which  trigger  the  automatic  generation  of  appointment  proposals.  In  this  way  it  is  possible  to  define  appointment  proposals  for  insemination,  aspiration,  transfer,  or  pregnancy  test.   If   an   event   is   triggered,   an   appointment   proposal   will   appear   in   MedITEX   Scheduler,   with   the   patient  name,   estimated   appointment   date   and   time,   and   treatment.   The   administration   of   an   oocyte-­‐triggering   drug,  for  example,  will  generate  an  appointment  proposal  for  oocyte  aspiration,  which  should  take  place  36  hours  after  the  drug  administration.  In  another  example  the  setting  of  a  transfer  date  in  MedITEX  IVF  in  the  future  will  generate  a  transfer  appointment  proposal  in  MedITEX  Scheduler.      The  user  can  change  the  following  settings  for  each  of  predefined  events:   • Active:  Defines  if  an  event  triggers  an  appointment  or  not.   Page  5  of  22  
  • 6. • h   (time   after   the   event):  Defines  the  start  of  the  appointment,  in  hours,  after  the  date  and  time  of  the   triggering  event.   • Appointment  /  Treatment:  All  treatments  defined  in  Scheduler  can  be  chosen  here.   • Rule:  An  additional  condition  for  the  start  time  of  the  proposed  appointment.      12.)  Report  editor:     a. A   certain   number   of   tables   and   fields   in   report   editor   have   been   revised,   in   order   to   ease   the  creation   of  user-­‐defined  queries.  As  a  consequence  it  may  happen  in  rare  cases  that  some  existing  queries  can   no  more  be  executed.     If   you   encounter   such   a   problem,   please   contact   directly   the   software   support.   We   will   help   you   to   restore  the  query  in  question.  The  support  can  be  reached       Mon.  to  Thu.   from  8:30  CET  to  17:00  CET     Friday       from  8:30  CET  to  14:00  CET     Hotline     +49  941  56  99  87  70     Email       support@critex.de     Fax       +49  941  56  99  77  40     b. In  the  report  editor  results  window  it  is  now  possible  to  refresh  the  result  with  the  "Refresh"  button,   without  the  need  to  go  back  to  query  design  window  and  run  the  query  again.     c. For   letter   templates   created   in   Word   module   there   are   several   new   "additional   placeholders"   now   available:  for  ultrasound  images,  similarly  to  embryo  images,  and  for  current  date  and  time.     d. To   facilitate   evaluations   over   different   couples,   the   new   field   "couple"   in   therapy   and   inseminations   table  was  introduced.      13.)  Main  menu:     Over  the  menu  item  “FileàChange  User”  users  can  now  only  switch  to  another   user,  or  log  off.  In  order  to  continue  using  the  program  with  the  same  user  it  is   necessary  to  enter  the  password  first.        14.)  Interfaces:     a. Interface  to  Synlab:  Web  orders  of  laboratory  parameters  with  Synlab.     b. MedITEX  DocLink     The   new   Add-­‐On   "MedITEX   DocLink"   enables   quick   and   easy   importing   of   files   into   the   different   areas   of   MedITEX  IVF.       The  files  to  be  imported  can  be  sent  with  the  right  mouse  click  directly  to  MedITEX  DocLink.  The  other   possibility   is   to   drag   and   drop   them   directly   into   the   opened   MedITEX   DocLink   window.   Using   the   buttons  in  top  area  the  document(s)  can  be  stored  for  one  patient  in  different  program  areas:   Page  6  of  22  
  • 7.           1.  Patient  document  storage   a.  Patient  data  (general  document,  attention  message,  note)   b.  Laboratory  diagnosis  (grouped  after  laboratory  values)   c.  Examination  (in  all  existing  examination  types)   2.  Oocyte/Embryo  development   3.  Incubators   4.  Semen  analysis  (general,  native,  preparation)   5.  Ultrasound  examinations                                                  15.)  Double  Witnessing:  statistical  examination  of  50  spermiograms     Each   50   pairs   of   native   sperm   counting   values   (documented   in   50   double-­‐witnessed   semen   analysis)   will   be  automatically   checked   based   on   a   predefined   set   of   statistical   rules.   If   the   assessment   does   not   give   a  satisfactory   result,   the   Double   witnessing   function   will   be   blocked   for   further   use   and   can   only   be   unlocked   by  an  authorized  employee.  The  results  of  all  automatic  tests  including  the  individual  values  of  50  sperm  counting  values  can  be  reviewed  over  the  menu  "Reports-­‐>Double  witnessing  administration”.  In  this  module  it  is  also  possible  to  unlock  the  Double  witnessing  functionality,  once  when  it   was  blocked  by  the  system.  The  new  staff  function   "Activate   Double   witnessing   functionality"   in   "SystemàSettingsàStaffàEdit   Staff",   determines  whether  the  employee  is  authorized  to  unlock  the  Double  witnessing  function.       Page  7  of  22  
  • 8. 16.)                         MedITEX  Scheduler     a. Automatic  proposal  of  appointments:     An   automatic   generation   of   proposed   appointments   is   now   possible   (e.g.   for   aspiration,   insemination,   transfer   etc.).   If   the   appropriate   rules   have   been   defined   and   activated   in   system   settings   of   MedITEX   IVF   (see   also   point   11),   the   corresponding   event   will   automatically   generate   a   proposed   appointment   in   the   scheduler,   if   the  date  is  not  in  the  past.  All  proposed  appointments  can  be  reviewed  in  MedITEX  Scheduler  under   “MenuàAppointmentsà  Proposed  appointments”.         By  double  clicking  on  a  cell  (or  by  clicking  the  button  "Take  over  appointment"),  the  appointment  input   mask  will  be  opened  with  the  proposed  data  -­‐  patient,  treatment,  appointment  start  –  already  filled   out,  if  no  active  appointment  already  exists.   User  can  now  edit  the  appointment  data  and  save  it,  thus   creating   an   active   and   “real”   appointment.   The   corresponding   proposed   appointment   will   automatically   be   transferred   to   the   tab-­‐sheet   “History”,   with   the   information   about   the   start   of   the   generated  appointment.  By  double-­‐clicking  the  line  with  the  proposed  appointment  to  which  an  active   appointment  already  exists  (e.g.  has  already  been  generated),  the  “real”  appointment  will  be  opened.       If   the   triggering   event   in   MedITEX   IVF   has   changed   in   time,   the   corresponding   appointment   will   be   automatically  transferred  back  to  the  tab-­‐sheet  "Proposed  appointments”,  and  marked  in  red  (only  if   the   corresponding   “real”   appointment   lies   still   in   the   future).   In   this   way   the   user   can   immediately   react  if  something  changes  in  the  planning.         Page  8  of  22  
  • 9. b. Patient  location:                                         The   virtual   waiting   room   has   been   expanded   and   converted   into   the   “patient   locator”.   In   the   column   "Room"   it   is   now   possible   to   select   a   room   where   the   patient   is   presently   located.   In   the   column   "Since   [hh:mm]"  the  time  is  displayed,  since  when  the  person  is  in  that  room.     As  before  it  is  possible  to  drag  the  whole  appointment  and  drop  it  in  the   patient   location   area.   The   “Waiting   room   1”   will   be   automatically   entered  in  the  location  column,  and  the  appointment  status  will  be  set   to  “Patient  is  in  waiting  room”.       The   status   of   the   appointment   can   be   edited   via   the   context   menu   that   appears   on   right-­‐clicking   the   appointment,   or   via   the   context   menu   in   the   patient   location  area.     In  the  details  window  "Patient’s  location”,  which  can  be  invoked  over  the   link   in   the   upper   left   corner   of   the   main   window,   it   is   possible   to   see   more  details  about  the  actual  location  and  appointment  of  each  patient   currently   present   in   the   clinic.   Here   it   is   also   possible   to   filter   the   data   by   a   particular   calendar,   so   that   only   the   appointments   related   to   that   calendar  are  displayed.                       Page  9  of  22  
  • 10.   The   rooms   can   be   defined   in   the   program   settings   (Menu:   “SystemàSettings”)   as   a   calendar   with   the   group   type   “Room”.   Additionally   it   is   possible   in   general   settings   to   specify   the   total   number   of   all   waiting  rooms.            Bugs  fixed     1.) Query  builder:     a. The  performance  of  queries  over  inseminations  was  increased.   b. The   new   fields  "used  drugs"  in  the   fields   of   therapy  and  inseminations  also   allows   the   search   for  therapies  in  which  a  particular  drug  was  (or  was  not)  used.     2.) Semen  analysis:   a. In  the  spermiogram  window,  the  time  of  the  acquisition  is  no  longer  doubled.   b. The  motility  percentage  values  are  now  displayed  with  no  decimal  places.     3.) Therapy  overview:     a.  The  problem  with  editing  and  deleting  of  hormones  after  entering  certain  drugs  has  been  fixed.     4.) Culture:   a. If  a  2PN-­‐cell  develops  into  a  >=  3PN-­‐cell,  and  then  be  set  to  "arrest"  or  “discarded”,  then  this   cell  will  be  added  in  the  tabular  cultural  view  to  the  field  "discarded",  in  "2PN-­‐selection"  area.     5.) Pregnancy:   a. Time  difference  between  the  current  pregnancy  week  and  abortion  week  was  fixed.     b. Refresh  problems  in  pregnancy  and  birth  forms  were  fixed.           Page  10  of  22  
  • 11. Version  1.2.2.1  Features       1.) The   main   screen   of   MedITEX   IVF   has   been   redesigned   to   create   space   for   the   display   of   8   most   important  laboratory  examinations  according  to  EU  guidelines.  The  messages  area  and  the  laboratory   values  can  be  both  edited  by  double-­‐clicking  the  information  row.         The  list  of  the  results  of  8  examinations  displayed  here  is  fixed,  regardless  of  which  laboratory  values   have   been   documented   in   the   patients   laboratory   area.   The   message   section   can   be   expanded   as   usual,  with  attention  messages  shown  as  first.      Version  1.2.1.7  Features         1.) Report  Editor:     a. All   QM   fields   inserted   and   used   in   any   of   the   areas   of   the   program   are   now   offered   in   appropriate  tables  of  the  Report  Editor  individually,  and  can  therefore  be  evaluated  and  used   for  generating  reports  and  letters  just  the  same  as  fixed  fields.             b. Laboratory  values  can  now  be  analysed  statistically:   Text   fields   in   Report   Editor   can   now   be   evaluated   as   numbers,   if   the   appropriate   conversion   has   been   selected   in   the   filter   window,   for   example   “Display   as   number”,   or   “Display   as   Page  11  of  22  
  • 12. floating-­‐point   number”.   In   this   way   it   is   now   possible   to   create   statistical   reports   (MIN/MAX/AVG)  on  all  values  that  have  been  stored  as  text.         c. In  the  Table  “Persons”  there  are  several  new  calculated  fields  offered:   -­‐ „Gravida“  and  „Para“,   -­‐ „Height“  and  „Weight“,  and   -­‐ „Number   of   internally   documented   aspiration   cycles   and   reproductive   pre-­‐treatments   from  the  most  recent  medical  history".     d. In  the  Table  “Transfer”  the  following  calculated  fields  have  been  offered:     -­‐ „Day  of  transfer“  (culture  day  when  the  transfer  occurred),  and   -­‐ „Number  of  transferred  Embryos“.     e. In  the  table  “Therapy”  it  is  now  possible  to  evaluate  if  the  children  have  been  born,  using  the   new  field  “Date  of  birth  of  the  first  born  child”.  In  this  way  it  is  not  necessary  to  add  the  table   “Children”   to   the   query,   and   in   the   result   there   will   be   no   doubled   lines   because   of   more   children.       2.) New  feature  –  “Signatures”:  create  and  use  personal  hand-­‐signatures  in  letters  and  reports.     For   each   employee   it   is   now   possible   to   add   a   personal   signature   in   System   Preferences   -­‐>   Staff,   either   directly   from   a   scanner,   or   from   a   previously   saved   image.   These   signatures   can   than   be   used   for   letter   templates,   by   adding   the   appropriate   placeholder   from   the   selection   of   „additional  placeholders“  to  the  letter  template  in  Word  Module.     It   can   either   be   a   signature   of   a   specific   person   or   a   general   signature   placeholder,   for   a   signature   of   a   person   that   should   be   selected   from   the   list  of  possible  signature-­‐holders  on  generating  the  specific  letter.   The  use  of  signature  feature  can   also   be   protected   by   a   personal   password,   so   that   only   the   entitled   employees   can   create   signed  letters.         3.) The  “QM  Free  Fields”  have  been  extended  to  100  characters.     Page  12  of  22  
  • 13. 4.) Follicle  aspiration:  3  new  fields  were  added  to  the  “Additional  details”  area:   – “Size  of  the  leading  follicle”,   – “#  Aspirated  left”,  and     – “#  Aspirated  right”.     5.) Culture:  Each  one  of  the  three  culture  views  can  now  be  exported  to  the  Notebook,  by  clicking  on  a   camera  symbol  positioned  on  the  culture  tab  sheet,  left  to  the  view’s  title.       6.) Graphical  culture  representation:   a. The   number  of  culture  days  in   the   graphical   representation  of   the  culture  can   now   be   freely   defined  between  6  and  9  days,  in  System  –  Display  options.  Default  is  9  days.       b. Different  spermiogram  for  each  oocyte:   Using   the   two   new   buttons   to   the   right   of   the   treatment’s   spermiogram   area,   in   it   is   now   possible   to   add   and   remove   additional   spermiograms.   In   the   new  column  “SP”,  it  is  possible  to   assign   another   spermiogram   to   each   oocyte   by   right-­‐clicking   in   the   table   cell   “SP”   of   a   particular   oocyte.     c. On   editing   the   oocytes   (right   mouse   button   on   the   oocyte),   only   the   options   that   are   applicable  on  that  particular  day  are  available.       d. Oocyte  images  –  new  possibilities:   i. If   there   are   images   deposited   for   an   egg   /   embryo,   the   preview   image   will   automatically  appear  in  a  preview  window  when  the  mouse  stands  still  over  the  cell.   ii. With  the  new  check-­‐box  “Photo  view”  it  is  possible  to  switch  between   pictograms  and  oocyte  images.     In   both   cases   the   main   image,   so   called   “Preview   image”,   will   be   shown   –   in   a   preview   window   and   in   the   culture   table.   Per   default   is   the   first   added   image   automatically  the  “Preview  image”,  but  it  is  always  possible  to  choose  another  image   as  the  main  one,  in  the  Oocyte  Details  form.     iii. It   is   now   also   possible   to   export   the   oocyte   images.   With   the   new   button   “Export   image”   in   the   Oocyte   Details   form   the   selected   image   will   be   exported   to   the   Notebook.       e. Additional  embryo  stage  was  added:  “Early  morula”.       7.) Transfer:   a. The   same   image   preview   functions   from   the   point   6.d.   (above)   are   also   available   in   the   transfer  area,  for  each  transferred  embryo.     b. Double-­‐click  on  the  embryo  will  open  the  standard  form  with  all  embryo  details.     8.) Pregnancy:   It   is   now   possible   to   document   the   biochemical   pregnancy   also.   This   check-­‐box   field   is   not   connected   to   the   „Pregnancy   outcome“   field,   and   can   be   set   and   reset   independently.   In   the   report   editor   this   field   can   be   found   in   table   „Therapy“,   under   the   caption   „Pregnancy   -­‐   biochemical“,   and   in   table   „Pregnancy“  as  „Biochemical  PG“.       9.) Birth:  it  is  now  possible  to  enter  week  of  birth  for  each  child,  instead  of  date  of  birth.  If  the  date  of   birth  has  been  entered,  the  week  of  birth  will  automatically  be  calculated.     Page  13  of  22  
  • 14.   10.)  Treatment  list  in  the  program’s  main  window:   a. All   treatments   are   always   sorted   according   to   the   treatment   number,   so   that   the   newest   treatments  are  shown  first.     b. In  the  column  “Therapy”  the  corresponding  date  to  the  important  events  (FA,  TH,  ET)  is  now   also  shown.  If  the  aspiration  took  place  but  no  oocytes  have  been  found,  the  FA  event  will  be   shown  with  a  date  and  info  “0  Ooc”.       11.)  Treatment  overview:   a. „Copy   &   Paste“   functionality   is   now   implemented   in   drugs   area   of   the   treatment   calendar   (CTRL+C   and   CTRL+V).   It   is   possible   to   copy   and  paste   one   or   more   cells   at   once;   in   order   to   select  more  cells  please  select  the  first  cell,  hold  down  the  SHIFT  key  and  move  the  cursor  with   ARROW  keys  to  right  or  left.       b. Navigation  with  cursor,  tab  and  enter  key  is  now  also  possible  in  calendar.     c. Values  of  5  selected  hormones  in  the  calendar  can  now  be  typed  directly  in  the  calendar  grid.   Double  click  on  any  cell  in  hormones  area  will  open  the  mask  with  detailed  data,  as  usual.     d. If   the   treatment   was   cancelled   the   reason   for   cancellation   is   now   shown   in   the   treatment   overview  alongside  with  the  cancellation  date.     e. In  the   treatment   overview   the   cycle   day   is   now   shown   below   the   cycle  date  in  calendar.  The  width  of  calendar  columns  can  be  edited   in  System  -­‐>  Display  options.   f. If  the  end  of  the  treatment  is  set  in  the  events  row  in  calendar,  the  timeline  will  therewith  also   be  ended.       g. The   application   domain   of   a   drug   is   now   shown   in   a   hint.       12.)  Treatment  –  treatment  spermiogram:   a. The   text   in   the   treatment   row   is   now   coloured   red,   if   the   spermiogram   is   missing   or   is   not   fitting  to  the  treatment.       b. When   assigning  a  treatment   spermiogram   in   therapy   it  is  now   possible  to   thaw   directly   from   the   cryo   storage.  In   the   drop-­‐down   selection   of   spermiograms   that   can  be   used   for   treatment,   the   cryo   preserved   spermiograms   are   now   also   offered.   These   spermiograms   are   marked   with   a  snowflake.     c. In   addition,  a   larger   selection   of   relevant   data  from   selected   spermiogram   is  displayed   in   the   treatment  form.     13.) Patient   photos   are   now   shown   in   the   therapy   header,   as   well   as   in   all   main   program   areas   such   as   Medical  history,  Lab.  diagnostics  and  Female/Male  examinations.     14.) Users   with   appropriate   right   can   now   edit   the   patient   IDs.   In   order   to   enable   a   certain   user   to   edit   patient   IDs   it   is   necessary   to   mark   the   corresponding   check-­‐box   in   the   “Edit   staff   data”   window,   under   the  System-­‐>Settings-­‐>Staff.     15.) On  creating  or  editing  a  medical  history,  the  date  of  first  interview  will  be  automatically  checked.  If  it  is   empty,  or  the  medical  history  date  is  older  than  the  date  of  first  interview,  the  confirmation  message   will  be  shown  and  the  user  will  have  the  possibility  to  automatically  update  the  date  of  first  interview.     16.) Findings  window  (Finding,  Attention,  Note):     Page  14  of  22  
  • 15. a. The  finding  window  is  now  sizeable.       b. The  size  of  the  note  edit  field  has  been  increased.  Different  text  formatting  functions  are  now   also  available.       c. One   finding   can   now   be   printed   or   exported   to   the   Notebook.   Data   from   the   finding   header   (patient  name,  date,  name  of  the  examinator)  will  also  be  printed   together  with  the  finding  text.  In  the  Notebook  it  is  then  possible   to   further   edit   the   data,   or   export   it   to   MS     Word,  for  example.     d. It  is  now  possible  to  attach  a  document  by  simply  drag  and  dropping  it  to  the  document  path   field  at  the  bottom  of  the  finding  window.     e. It  is  now  also  possible  to  scroll  through  different  findings  without  having  to  close  the  finding   window.       f. The  document  container  will  from  now  on  be  shown  only  if  there  are  documents   in   it.   Per   default   is   the   container   deactivated.   It   is   however   possible   to   turn   it   on   in  the  System-­‐>Settings  for  all  finding  windows.       17.) Program  settings:     a. In  the  “Staff”  window  there  is  a  new  check  box  field  “External”,  to  mark  external  resources.   b. A  new  unit  mlU/l  was  added  to  the  lab  area.     c. Material  charges  are  now  also  dependent  on  location  (in  clinics  with  more  than  one  location).     18.) Cryo  storage:   a. Female  cryo:  A  new  check  box  field,  „Ovarian  tissue“  is  offered.       b. Female   and   male   cryo:     A   new   date   field   is   offered,   „Storage   date“.   On   freezing   from   the   graphical  culture  view,  the  storage  date  will  be  automatically  set  equal  to  the  freezing  date.     19.) If   the   data   backup   did   not   properly   run   the   day   before,   MedITEX   will   show   an   info   message   to   the   users  with  admin  rights  after  start.      Bugs  fixed     5.) Corrected   problem   with   the   false   display   of   performed   treatment   for   insemination   therapies   where   the  insemination  method  –  heterologous  or  homologous  –  was  changed.   6.) The  faulty  display  of  an  oocyte  image  that  occurred  in  some  cases  when  trying  to  enlarge  the  image  by   double  clicking  on  it  has  been  corrected.     7.) MI  and  GV  oocytes  are  now  correctly  ordered  in  the  graphical  view.   8.) Embryos   that   were   freezed   or   set   to   “arrest”   in   the   graphical   representation,   are   now   correctly   shown   also  in  the  table  view.     9.) Only  the  cells  that  user  marked  with  “ET”  will  be  transferred  in  graphical  view.   10.) In  some  cases  it  happened  that  users  accidentally  thawed  oocytes  or  embryos  in  the  wrong  therapy.  In   order  to  prevent  it  the  program  now  compares  the  thawing  date  with  the  therapy  beginning.  If  it  does   not  fall  into  the  therapy  period,  the  corresponding  warning  message  will  be  issued.     Page  15  of  22  
  • 16. 11.) In   cancelled   treatments   the   treatment   outcome   will   be   automatically   set   to   “No   pregnancy”.   In   this   way   it   is   possible   in   pregnancy   queries   to   distinguish   between   cycles   with   no   pregnancy   and   cycles   where  the  pregnancy  was  not  yet  reported.   12.) The  error  message  that  appeared  when  saving  spermiogram  after  changing  the  spermiogram  data  and   generating  the  spermiogram  letter  is  eliminated.     13.) The   message   “Only   fertilized   cells   can   be   transferred”   which   in   some   cases   was   shown   by   mistake   was   corrected.   14.)  The   message   “Transfer   date   is   outside   of   boundaries”   which   in   some   cases   was   shown   by   mistake   when  trying  to  transfer  thawed  cells  was  corrected.      Version  1.2.0.4  Features       1.) A  new  stimulation  drug  was  included:  „Fostimon“.     2.) It   is   now   possible   to   duplicate   the   referrer   data.   In   this   way   it   is   possible   to   efficiently   add   more   referrers  with  the  same  address,  or  split  one  referrer  in  more.    Bugs  fixed     1.) The  message  "List  index  out  of  bounds",  which  came  sporadically,  is  fixed.      Version  1.2.0.0    Features       1.) Spermiogram:   a. It   is   now   possible   to   document   the   motility   of   sperms   also   according   to   the   current   WHO   directives:  as  progressive  [A+B],  non-­‐progressive  [C]  and  immotile  [D].  The  user  can  choose  in   the  system  settings  which  of  the  documentation  possibilities  should  be  used  by  default  (“old”   or  “current”  WHO  directive.)     b. The  field  „Inseminated  volume“  in  spermiogram  accepts  now  3  decimal  digits.     2.) System  settings  area  has  been  re-­‐organized.       3.) Different  design  and  performance  improvements  have  been  made  in  all  parts  of  the  program.     4.) Beside  the  "Estimated  date  of  birth"  in  pregnancy  mask  the  program  shows  now  also  the  actual  week   of  pregnancy  and  the  rest  days.     5.) Display  of  additional  information  in  hints  in  the  therapy  overview: a. In   laboratory   area   the   comments   to   each   hormone   are   shown   in   hint. If   no   comment   is   present,  the  standard  range  of  hormone  values  is  displayed.   b. In  drugs  area  the  prescripted  time  for  each  drug  is  shown,  if  present.      Bugs  fixed     1.) Report   editor:   It   is   now   possible   to   query   Insemination-­‐   and   non-­‐insemination   treatments   in   one   query.   2.) The  problem  of  sporadic  loss  of  information  for  some  oocyte  stages  (MII,  MI,  GV,  atretic)  is  fixed.   Page  16  of  22  
  • 17. 3.) „Spermiogram“-­‐>“Double   Witnessing“:   captions   „Person   1“   and   „Person   2“   have   been   renamed   into   „Counting  1“  and  „Counting  2“.    Version  1.1.1.8  Features       1.) Therapy  overview:  if  existing,  the  comment  for  each  drug  is  now  shown  in  hint.     2.) Overview  of  the  frozen  samples  of  man:   a. It  is  now  possible  to  open  the  related  spermiogram  directly  from  the  cryo  mask.   b. If   the   frozen   material   was   declared   as   donation,   this   information   is   now   shown   in   the   cryo   mask.     3.) Insemination,   aspiration,   transfer:   drop-­‐down   boxes   with   the   list   of   physicians   offer   only   the   staff   members  who  are  defined  as  physicians  in  staff  area  of  the  program  settings.     4.) A  new  staff  function:  embryologist   a. System  -­‐>  Settings  -­‐>  Staff:  A  new  function  –  Embryologist  –  was  introduced.   b. Follicle  aspiration,  embryo  transfer:  It  is  now  possible  to  select  the  operating  physician  and  the   embryologist  from  the  drop-­‐down  lists  of  physicians  and  embryologists  respectively.     5.) Aspiration:  a  new  field  “Time  of  aspiration”  was  introduced.     6.) MedITEX  Scheduler:   a. Direct  opening  of  the  patient  from  MedITEX  Scheduler  in  MedITEX  IVF   It   is   now   possible   to   open   the   patient   from   MedITEX   Scheduler   in   MedITEX   IVF   over   the   context  menu  from  the  patient  appointment  (right  mouse  click  on  appointment),  by  selecting   the  menu-­‐item  "Open  patient  in  MedITEX  IVF".  A  new  button  next  to  the  patient  search  box   does  the  same  for  the  patient  whose  name  is  entered  in  the  search  field.     In  order  to  use  this  feature  it  is  necessary  to  activate  it  in  the  MedITEX  Scheduler  settings.   b. Constrain  calendars:     It   is   now   possible   in   calendar   settings   to   constrain   any   calendar   to   a   certain   number   of   appointments  per  day  or  week.  If  on  creating  a  new  appointment  this  number  is  exceeded,  the   user  will  be  warned  with  a  message.     c. Reminders:     An  appointment  can  be  assigned  with  a  reminder.   d. Quick  selection:     A   drop-­‐down   list   offers   all   calendar   groups.  If   a   group   is   selected,   only   the   calendars   that   belong   to   that   group   will   be   displayed   in   the   overview.   Additionally   can   any   user   (with   its   own   user   name   and   password)   compose   and   save   own   calendar   selections   and   their   order,   using   the  „Define  calendar  selection“  feature.  These  sets  are  then  offered  in  addition  to  the  calendar   groups  in  the  drop-­‐down  list  for  quick  selection.   e. Special  selection:     A  new  button  "Special  selection"  enables  the  „back  and  forth“  switching  between  the  standard   calendar   view   and   a   special   selection   of   calendars   with   predefined   time   view   (day/days,   week,   year,  or  time  line).   f. View  of  appointment  types:   Pre-­‐defined,   superordinate   appointment   types   can   now   be   displayed   in   the   calendar   rows   directly.   g. Predefined  text  blocks:     A   new   feature   enables   the   user   to   easily   create   self-­‐defined   texts   and   sentences   (“Text   blocks”)  and  use  them  in  the  note  field  in  appointment  details  mask.       Page  17  of  22  
  • 18. Bugs  fixed     1.) When  thawing  the  Oocytes  in  the  stage  „PN“,  the  stage  will  automatically  be  shown  in  the  graphical   representation.   2.) Report   editor:   the   duplicated   entries   in   the   selection   of   possible   table   connections   (area   “Report   editor:  selection”)  have  been  removed.   3.) The  fertilized  Oocytes  that  were  declared  to  be  in  „GV“  or  „M1“  stage  in  graphical  representation  will   automatically  be  assigned  to  "0PN"  stage  in  table  representation.   4.) Patient  data  and  medical  history  areas:  the  problem  on  using  the  keyboard  shortcuts  has  been  fixed.   5.) Therapy  overview:  The  selected  additional  measures  can  be  changed  for  Insemination  therapies.   6.) List  of  plausibility  messages:  The  restriction  of  the  reference  date  has  been  fixed.   7.) Report  editor:   a. The  field  "Attending  physician"  is  offered  in  embryo  transfer  for  reporting.     b. The  field  "Reason  for  not  performed  ET"  is  offered  in  therapy  for  reporting.     c. It  is  now  possible  to  differentiate  between  “MI”  and  “GV”  oocytes  in  reports.   8.) Oocyte   development   mask:   In   all   personnel   drop-­‐down   lists   (in   AH,   PBD   and   PGD   areas)   only   the   embryologists  are  offered.   9.) Oocyte   development   mask:   On   scrolling   through   different   oocytes   the   PBD   data   will   be   saved   if   changed  (after  the  confirmation  by  the  user).   10.)  „System  -­‐>  Settings  -­‐>  Clinic“:  All  changes  of  data  in  this  area  will  be  immediately  effective.   11.)  Spermiogram:  Accessing  the  cryo  storage  out  of  one  spermiogram  (by  clicking  on  the  snow  flake)  will   open   the   cryo   storage   and   show   only   the   frozen   samples   of   that   spermiogram   and   not   all   the   samples   of  the  patient.   12.)  Pregnancy:   If   the   number   of   extra   uterine   amniotic   cavities   is   bigger   than   0,   the   field   „Was   the   pregnancy  therefore  terminated?“  will  not  be  set  to  “No”  automatically.      Version  1.1.1.7    Features       1.) Therapy  overview:     a. The  time  of  the  ovulation  induction  is  now  shown  in  the  overview.   b. The  period  of  the  calendar  is  increased  in  both  directions  (reference  date  +/-­‐  4  months).   c. A  new  button  enables  quick  re-­‐positioning  of  the  calendar  to  the  reference  date.      Bugs  fixed     1.) „System  -­‐>  Cryo  storage  “:  Caption  „unisex“  was  renamed  in  „all“.   2.) The   refresh   problem   when   saving   one   medical   history   that   contains   one   new   spermiogram   is   corrected.   3.) The  refresh  problem  in  graphical  representation  of  the  culture  which  occurred  when  the  user  tried  to   define  the  stage  for  thawed  materials  is  corrected.   4.) Information  in  main  window:   The   entries   in   the   Info   list   are   now   sorted:   first   the   CAVE,   and   then   other   messages.   The   scrollbar  is  positioned  in  the  upper  position.   5.) Plausibility  messages  list:  it  is  possible  now  to  filter  also  on  the  planned  therapies.    Version  1.1.1.6  Features       Page  18  of  22  
  • 19. 1.) Cryo  andro  storage:  a  new  field  „Donation“  has  been  introduced.  With  this  field  it  is  now  possible  to   mark  and  recognize  the  donor  samples.     2.) Referrers:   a. New   item   "Command",   "Address   label"   or   "Salutation   for   letter"   can   be   automatically  generated  for  all  active  referrers  using  one  of  offered  rules.   b. "Address   label"   can   be   generated   automatically   using   the   flash   symbol   on   the   right,   if   the   field  is  empty.   c. A  new  Referrer  type  has  been  introduced:  “MCC”  (Medical  care  center).     3.) The   database   backup   tool   creates   a   protocol   after   every   backup.   The   protocol   can   be   opened   from   menu  item  „Help  -­‐>  Protocols  -­‐>  Data  backup“.     4.) Report   editor:   A   double   click   in   the   result   list   of   a   query   containing   referrer   data   will   directly   open   the   corresponding  referrer.     5.) Previous  pregnancies:  new  field  „Delivery  method“.     6.) Report  editor:  The  string  fields  can  be  converted  to  numbers  (with  or  without  decimals)  in  the  result   list.  This  can  be  set  for  each  field  in  the  “Conditions”  view  of  report  editor,  before  the  execution  of  the   query.       7.) „System   -­‐>   Settings   -­‐>   System   tables“:   three   new   system   tables   offer   the   possibility   to   predefine   score   texts:   a. Score  for  oocytes   b. Score  for  PNs   c. Score  for  Embryos     This   user-­‐defined   scores   can   be   selected   in   the   graphical   representation   of   culture   and   in   transfer   mask  from  a  drop-­‐down  list  in  the  score  field.  It  is  of  course  also  possible  to  write  the  individual  score   text  directly  in  the  field.    Version  1.1.1.0    Features       1.) „System-­‐>   Change   user“:   The   possibility   to   log-­‐in   as   another   user   without   having   to   restart   the   program.  The  keyboard  shortcut  is  “F2”.     2.) To  improve  the  readability  of  frozen  samples  in  cryo  storage,  the  number  of  frozen  oocytes,  PNs  and   embryos  are  now  centred  and  written  in  bold.    Bugs  fixed     1.) Culture,  graphical  representation:  with  the  menu  items  “ET  ideal”  or  “ET  not  ideal”  it  is  now  possible   to  toggle  between  “transferred”  and  “not  transferred”.     2.) Therapy  planning:  It  is  now  possible  to  edit  „free  entries“.   3.) Note  block:   a. If   the   note   block   is   opened,   it   is   now   possible   to   create   standard   Windows   screenshots   with   the  keys  “PRINT”  and  “ALT+PRINT”.  Version  1.1.0.98    Features       Page  19  of  22  
  • 20. 1.) Locations  functionality:  new  field  “Location”  is  now  offered  in  patient  data  area  for  both  partners.  The   information  selected  there  will  also  be  shown  in  the  main  window  beside  the  patient  name.     2.) It  is  now  possible  to  thaw  more  probes  at  once  using  the  multiple  selection.     3.) Report  editor:  "last  measured  HCG  value"  is  offered  as  a  calculated  field.    Bugs  fixed     1.) Apparent   „freeze“   of   the   program   if   "Always   on   top"   check   box   in   QM   window   was   set   has   been   fixed.  The  QM  window  has  concealed  the  windows  message  that  required  the  user  input.  This  system   messages   are   now   displayed   „on   top“   of   all   other   windows,   so   that   the   user   can   continue   working   normally.   2.) Spermiogram,  double  witnessing:     a. A  system  message  indicates  if  there  is  data  missing.   b. The  traffic  lights  are  set  to  red  if  the  counting  sum  is  not  equal  100.   3.) The  text  indicating  that  associated  medical  history  of  the  man  is  missing  was  corrected.   4.) Problem  of  saving  the  preparation  time  was  corrected.    Version  1.1.0.95    Features     1.) Polar  body  diagnosis:   a. Based   on   the   selection   of   the   probes,   the   corresponding   chromosomes   in   the   fields   "PB1"   and   "PB2"  will  be  automatically  filled  as  a  group  and  the  ploidy  set  to  "n.a.".   b. When   taking   over   the   PBD   data   of   another   oocyte   the   fields   “PB1”   and   “PB2”   will   be   filled   according  to  the  probes  of  another  oocyte  with  “n.a.”.     2.) Culture:   a. The  field  “immature”  for  the  aspirated  oocytes  has  been  renamed  to  „GV“.   b. A  new  field  for  the  aspirated  oocytes:  „MI“.     3.) Search   for   patients   mask   in   the   main   window:   with   the   buttons   “previous”   and   “next”   it   is   now   possible  to  browse  through  previously  opened  patients.  The  drop-­‐down  list  of  patients  now  shows  all   previously  opened  patients  if  the  patient  search  field  is  filled;  if  the  patient  search  field  is  empty,  the   drop-­‐down  list  will  contain  all  the  patients  in  the  database.     4.) Report  editor:   a. A  new  condition  in  condition  window:  „in/before  n  DAYS“  is  now  offered.   b. Conditions  of  a  query  are  shown  also  in  the  Charts.   c. New  field  in  Therapies  -­‐>  Transfer:    Sum  of  all  transferred  cells.   d. New  fields  in  therapy:     i. Sum  of  all  transferred  cells     ii. Cumulative  dosage  FSH  [IU]     iii. Cumulative  dosage  LH  [IU]     iv. Cumulative  dosage  hMG  [IU]     v. Cumulative  dosage  l.a.FSH  [μg]   vi. Stimulation  duration  [Days]     5.) A  new  feature  enables  the  user  to  influence  the  result  of  a  query  by  setting  “all  data”  or  “intersection”,   as  the  mode  of  connecting  the  tables.   If  you  select  tables  “patients”  and  “therapies”,  and  link  them  together,  you  can  influence  the  result  in   the  following  way:   Page  20  of  22  
  • 21. a.  „All“  –  All  patients,  including  those  who  have  no  therapies  documented.   b.  „Intersection“    -­‐  Only  the  patients  that  also  have  therapies.     6.) System   settings:   QM   fields   can   now   be   removed   from   the   QM   area   allocation,   without   influencing   the   already  used  fields.         7.) A  new  item  “Subsidy”  is  now  offered  for  patient’s  billing  category.       8.) BMI  was  constrained  to  one  decimal  place.     9.) It  is  now  possible  to  associate  a  medical  history  with  a  therapy  directly  from  the  main  window.      Version  1.1.0.93    Features     1.) The   automatic   sorting   of   oocytes   and   embryos   based   on   quality   in   graphical   representation   of   cell   culture  can  be  switched  off  in  program  settings.    In  that  case  the  cells  will  be  sorted  based  on  their  IDs.     2.) Therapy  planning:  Incompletely  documented  drugs  will  be  coloured  red.  Before  generating  the  therapy   out  of  the  planned  one,  a  message  requiring  the  completion  of  missing  drug  data  will  be  issued.     3.) New  fields  in  Follicle  Aspiration  and  Transfer  views:  “Attending  physician”.     4.) It   is   now   possible   to   automatically   create   the   patient   ID   on   creating   new   patient   record.   The   rule   for   the   patient  ID  generation  can  be  found  in  „Settings  -­‐>  System  -­‐>  Miscellaneous“     5.) The   lists   of   previous   illnesses   and   infertility   factors   in   medical   history   can   now   be   freely   edited   and   extended  in  „Settings  -­‐>  System  tables  -­‐>  Edit  system  tables“     6.) New   feature   in   spermiogram   view:   „Double   Witnessing”.   This   function   is   the   part   of   quality   management   procedures   for   laboratory   analysis   according   to   the   “Directive   of   the   Federal   medical   association  of  Germany  for  Quality  assurance  of  quantitative  lab  examinations”.  Double  Witnessing  can   be  activated  in  „Settings  -­‐>  System  -­‐>  Miscellaneous“.     7.) New   feature   in   QM/Free   fields   view:   „Voice   recording”.   With   this   function   you   can   record   voice   messages  in  almost  each  area  of  MedITEX  IVF,  and  check  them  later  in  “Reports  -­‐>  Voice  messages”.       8.) New   feature   in   the   therapy/treatment   view:   a   printable   “Treatment  sheet”.   With   a   click   of   a   button   it   is   now   possible   to   produce   a   printable   sheet   with   all   relevant   treatment   data:   important   events,   medication,  hormone  levels  and  ultrasound  data.  It  can  be  produced  either  from  the  therapy  planner,  as   a   memo   for   the   patient   for   planned   treatment   steps,   as   well   as   after   the   treatment   with   all   collected   data.     9.) New   feature   in   all   views:   “Screenshot   /   note   block”.   In   the   title   of   all   program   views   there   is   now   a   camera   symbol.   By   clicking   on   this   symbol   a   screenshot   of   the   actual   view   will   be   produced   and   inserted   in  the  notepad  document.  This  document  can  be  freely  edited  and  extended  with  further  screenshots.   The   notepad   can   also   be   started   by   right-­‐clicking   on   the   MedITEX   IVF   in   Windows   system   area   (lower   right  corner  of  the  screen,  left  from  the  clock).     10.) Female  and  male  medical  histories  were  extended  with  many  new  fields.     11.) In  Follicle  Aspiration  and  Transfer  view  it  is  now  possible  to  document  the  attending  physician.     Page  21  of  22  
  • 22. 12.) When   cryo   conserving,   if   user   defined   straw   ID   was   already   used   for   another   straw   the   system   will   issue   a  warning.     13.)  Program  performance  and  responsiveness  was  generally  improved  in  all  areas.     14.)  A  new  function  in  the  view  “Culture  day  /  Development  stage”  offers  the  possibility  to  browse  through   the   oocytes   and   development   days   without   having   to   close   the   culture   day   window.  It   is   also   possible   to   open  the  culture  day  view  in  culture  by  pressing  the  enter  key.     15.)  In  the  culture  graphic  view  the  relative  oocyte  number  is  now  also  shown.     16.)  It  is  now  possible  to  edit  lab  parameters.  In  „Settings  -­‐>  System  -­‐>  System  tables“  you  can  individually   edit  the  parameter  data,  as  well  as  create  new  parameters.     17.)  It  is  now  possible  to  add  new  staff  member  without  having  to  define  username  and  password.  In  this   way  you  can  quickly  define  new  staff  members  that  can  be  selected  in  the  program,  but  cannot  log  in   themselves  (e.g.  anaesthesiologists).     18.)  A  new  drug  was  included:  „Elonva“,  a  long-­‐acting  rec  FSH  for  stimulation  of  the  ovaries.     19.)  If  the  straw  was  frozen  directly  out  of  the  spermiogram  view,  the  cryo-­‐icon  (snowflake)  will  be  painted   blue  to  signalize  the  existing  of  the  cryo  data.         20.)  In   order   to   offer   the   newest   MS   Office   functions   and   features   for   creating   reports   and   letters   in   our   system,  we  continuously  update  our  software.  Therefore  we  can  guarantee  for  the  compatibility  of  our   software  system  with  MS  Office  2003  and  latter.  Thank  you  for  your  understanding.      Bugs  fixed     1.) If  a  patient  is  deleted  from  the  system,  all  linked  straws  in  the  cryo  storage  will  also  be  deleted.   2.) The  performance  of  letter  creation  in  the  report  editor  improved.     3.) The   warning   in   the   transfer   view   was   adjusted   in   the   following   way:   „Date   of   transfer   is   greater   than   date  D0  (follicle  aspiration  resp.  cryo  thawing)  plus  10  days“.   4.) Report  editor:   1. The  term  „QM  function“  was  corrected  in  „QM  Description“,  for  better  understanding.   2. Duplicate  data  is  not  shown  in  the  query  result  anymore.   5.) The  patient  height  is  also  shown  in  the  header  of  the  Lab  diagnosis  area.   6.) MedITEX  IVF  –  OCTAX  interface:   1. It  is  now  possible  to  import  oocyte  pictures  from  OCTAX  even  if  the  corresponding  oocyte  does   not  yet  exist  in  MedITEX  IVF.  During  the  import  the  oocyte  will  automatically  be  created  in  the   appropriate  culture  day  in  the  culture  graphical  view.   2. The  pictures  from  OCTAX  can  be  assigned  to  all  oocyte  stages.   7.) Refresh  problem  during  the  patient  change  in  the  pregnancy  view  is  corrected.   8.) Instead  of  the  partner  data  in  the  title  of  cryo  storage  administration,  the  patient  data  is  shown.   9.) For  an  embryo  transfer  that  was  not  carried  out:  if  the  reason  is  not  stated,  the  plausibility  message  of   the  system  will  be  issued.   10.)  Corrected:  refresh  problem  with  the  selection  of  a  reason  for  embryo  transfer  that  was  not  carried  out.   Page  22  of  22