Thyroid - Goiter

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Thyroid - Goiter

  1. 1. Most common manifestation of thyroid disease www.medicinemcq.com 1
  2. 2. Enlargement of the thyroid www.medicinemcq.com 2
  3. 3. 1. Is the goiter diffuse or nodular? 2. Is it nontoxic or toxic? 3. Is it causing any local compressive or cosmetic problems? 4. Is it benign or malignant? www.medicinemcq.com 3
  4. 4. Diffuse goiter Multinodular goiter Solitary nodule www.medicinemcq.com 4
  5. 5.  Iodine deficiency (endemic goiter)  Simple goiter  Hashimoto's thyroiditis  Graves' disease  Transient thyroiditis  Drugs  Iodine, amiodarone, lithium  Suppurative thyroiditis  Dyshormonogenesis  Riedel's thyroiditis www.medicinemcq.com 5
  6. 6.  Colloid nodule - most common and do not have an increased risk of malignancy  Simple cyst  Follicular adenoma - Most follicular adenomas are benign  Carcinoma  Lymphoma  Thyroiditis www.medicinemcq.com 6
  7. 7.  Most common cause - dietary iodine deficiency  Impaired synthesis of thyroid hormone  Compensatory rise in the serum TSH  Hypertrophy and hyperplasia of thyroid follicular cells  Euthyroid state www.medicinemcq.com 7
  8. 8. Diffuse nontoxic (simple) goiter  enlarged follicles filled with colloid  also called colloid goiter www.medicinemcq.com 8
  9. 9.  With time, recurrent episodes of hyperplasia and involution  irregular enlargement of the thyroid and nodule formation  thyroid nodule - a lesion in the thyroid gland due to an abnormal focal growth of thyroid cells  All long-standing simple goiters convert into multinodular goiters www.medicinemcq.com 9
  10. 10. No physiologic increase in thyroid volume Goiter during adolescence is pathologic For rest of the slides visit www.medicinemcq.com > Thyroid www.medicinemcq.com 10

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