Ns11 Limbic System

Slide 1: Limbic System Dr. Skantha Kandiah MBA, MSc (NUI), MB BCh BAO (NUI), LRCP & SI Senior Lecturer in Anatomy and Lecturer in Healthcare Management RCSI

Slide 2: Limbic System • Cingulate gyrus • Hippocampus • Fornix • Mamillary bodies • Septal nuclei • Amygdala

Slide 7: FORNIX • CONNECTS MAMMILLARY BODIES TO HIPPOCAMPUS • Efferent fibres from hippocampus form fimbria

Slide 9: • NUCLEUS ACCUMBENS – Stimulation – sense of well-being – Connection to basal nuclei – • motor expression of emotion? – SEPTAL AREA – stimulation – sensation like orgasm • Destruction of septal area -- rage

Slide 10: AMYGDALA • At tip of tail of caudate nucleus and anterior horn of lateral ventricle • Fear – important for survival • ? Overactivity – rage • ? Role in phobias Bilateral ablation – timidity, hypersexuality.

Slide 12: HIPPOCAMPUS • IMPORTANT FOR MEMORY • 3 layers of cells (allocortex) • Alzheimer’s disease – General cortical degeneration – Hippocampal degeneration (bilateral) – cannot form new memories – Frontal degeneration – inappropriate behaviour, later -= attention and motivation deficit