Honors Biology
Growth and Development and
Cellular Inheritance
Introduction
Asexual Reproduction
Sexual Reproduction
Growth and Development
2n = 20
A chicken has 78 Chromosomes in
its Somatic Cells:
• How many chromosomes did the chicken
inherit from each parent?
• How ...
http://www.youtube.com/watch?v=m73i1Zk8EA0&feature=related
How many
chromosomes are
shown in this
diagram? How
many chromatids
are shown?
on
ati
g
lon
e
of
e
on
Z

a
pic
A

Compare the number of cells in
interphase, prophase, metaphase,
anaphase or telophase i...
Yeast Life Cycle
Budding Pattern
Yeast Mating Types
Uncontrolled Growth
Angiogenesis
Apoptosis
“Immortal Cells”
Telomerase
Metastasis
Immune System
What would
happen if you
performed this
experiment with
cancer cells?
Henrietta Lacks
HeLa cells
Stem Cell

Stem Cell video
Stem Cell Sources
Embryonic Stem Cells (ES)
In Vitro Fertilization

Louise Brown – Birthday 1978
Nuclear Transfer
Adult Stem Cells
iPS
IPS
http://www.youtube.com/watch?v=fGNchPdlaGU&NR=1&feature=fvwp
http://www.youtube.com/watch?v=cPvidAvzmx0&feature=relate...
STAP cells

Haruko Obokata.
Controversial therapy.Mitochondrial DNA replacement could help carriers of severe disease
have healthy children.

G Vogel ...
Meiosis
Honors Biology
Aneuploidy Article
Honors Biology
General Background Questions:

• What is the genome, transcriptome and
•

the proteome?
What is aneuploidy?
Experiment Questions:

• What was the “conundrum” they identified
•

in the Introduction?
What are the two experimental
qu...
Meiosis Question:

• Diagram why meiosis with odd ploidy (3N
or 5N) would produce aneuploids.
Key Findings

•

What are key
findings from:
ab, ef, and gh?
A16
Why is strain
A16 a good
strain to
focus on for
experimental
question?
ATR1

• What are: C•

some XIII, ATR1,
4-NQO, and
Strain A16?
What is their
relationship?
Proteome &
Transcriptome:
Gene dosage effect or
dosage compensation
Aneuploidy has global and complex
effects on both the ...
Honors ~ Cell cycle,mitosis and meiosis 1314
Honors ~ Cell cycle,mitosis and meiosis 1314
Honors ~ Cell cycle,mitosis and meiosis 1314
Honors ~ Cell cycle,mitosis and meiosis 1314
Honors ~ Cell cycle,mitosis and meiosis 1314
Honors ~ Cell cycle,mitosis and meiosis 1314
Honors ~ Cell cycle,mitosis and meiosis 1314
Honors ~ Cell cycle,mitosis and meiosis 1314
Honors ~ Cell cycle,mitosis and meiosis 1314
Honors ~ Cell cycle,mitosis and meiosis 1314
Honors ~ Cell cycle,mitosis and meiosis 1314
Honors ~ Cell cycle,mitosis and meiosis 1314
Honors ~ Cell cycle,mitosis and meiosis 1314
Honors ~ Cell cycle,mitosis and meiosis 1314
Honors ~ Cell cycle,mitosis and meiosis 1314
Honors ~ Cell cycle,mitosis and meiosis 1314
Honors ~ Cell cycle,mitosis and meiosis 1314
Honors ~ Cell cycle,mitosis and meiosis 1314
Honors ~ Cell cycle,mitosis and meiosis 1314
Honors ~ Cell cycle,mitosis and meiosis 1314
Honors ~ Cell cycle,mitosis and meiosis 1314
Honors ~ Cell cycle,mitosis and meiosis 1314
Honors ~ Cell cycle,mitosis and meiosis 1314
Honors ~ Cell cycle,mitosis and meiosis 1314
Honors ~ Cell cycle,mitosis and meiosis 1314
Honors ~ Cell cycle,mitosis and meiosis 1314
Honors ~ Cell cycle,mitosis and meiosis 1314
Honors ~ Cell cycle,mitosis and meiosis 1314
Honors ~ Cell cycle,mitosis and meiosis 1314
Honors ~ Cell cycle,mitosis and meiosis 1314
Honors ~ Cell cycle,mitosis and meiosis 1314
Honors ~ Cell cycle,mitosis and meiosis 1314
Honors ~ Cell cycle,mitosis and meiosis 1314
Honors ~ Cell cycle,mitosis and meiosis 1314
Honors ~ Cell cycle,mitosis and meiosis 1314
Honors ~ Cell cycle,mitosis and meiosis 1314
Honors ~ Cell cycle,mitosis and meiosis 1314
Honors ~ Cell cycle,mitosis and meiosis 1314
Honors ~ Cell cycle,mitosis and meiosis 1314
Honors ~ Cell cycle,mitosis and meiosis 1314
Honors ~ Cell cycle,mitosis and meiosis 1314
Honors ~ Cell cycle,mitosis and meiosis 1314
Honors ~ Cell cycle,mitosis and meiosis 1314
Honors ~ Cell cycle,mitosis and meiosis 1314
Honors ~ Cell cycle,mitosis and meiosis 1314
Honors ~ Cell cycle,mitosis and meiosis 1314
Honors ~ Cell cycle,mitosis and meiosis 1314
Honors ~ Cell cycle,mitosis and meiosis 1314
Honors ~ Cell cycle,mitosis and meiosis 1314
Honors ~ Cell cycle,mitosis and meiosis 1314
Honors ~ Cell cycle,mitosis and meiosis 1314
Honors ~ Cell cycle,mitosis and meiosis 1314
Honors ~ Cell cycle,mitosis and meiosis 1314
Honors ~ Cell cycle,mitosis and meiosis 1314
Honors ~ Cell cycle,mitosis and meiosis 1314
Honors ~ Cell cycle,mitosis and meiosis 1314
Honors ~ Cell cycle,mitosis and meiosis 1314
Honors ~ Cell cycle,mitosis and meiosis 1314
Honors ~ Cell cycle,mitosis and meiosis 1314
Honors ~ Cell cycle,mitosis and meiosis 1314
Honors ~ Cell cycle,mitosis and meiosis 1314
Honors ~ Cell cycle,mitosis and meiosis 1314
Honors ~ Cell cycle,mitosis and meiosis 1314
Honors ~ Cell cycle,mitosis and meiosis 1314
Honors ~ Cell cycle,mitosis and meiosis 1314
Honors ~ Cell cycle,mitosis and meiosis 1314
Honors ~ Cell cycle,mitosis and meiosis 1314
Honors ~ Cell cycle,mitosis and meiosis 1314
Honors ~ Cell cycle,mitosis and meiosis 1314
Honors ~ Cell cycle,mitosis and meiosis 1314
Honors ~ Cell cycle,mitosis and meiosis 1314
Honors ~ Cell cycle,mitosis and meiosis 1314
Honors ~ Cell cycle,mitosis and meiosis 1314
Honors ~ Cell cycle,mitosis and meiosis 1314
Honors ~ Cell cycle,mitosis and meiosis 1314
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  • Controversial therapy.Mitochondrial DNA replacement could help carriers of severe disease have healthy children.
  • Honors ~ Cell cycle,mitosis and meiosis 1314

    1. 1. Honors Biology Growth and Development and Cellular Inheritance Introduction
    2. 2. Asexual Reproduction
    3. 3. Sexual Reproduction
    4. 4. Growth and Development
    5. 5. 2n = 20
    6. 6. A chicken has 78 Chromosomes in its Somatic Cells: • How many chromosomes did the chicken inherit from each parent? • How many chromosomes are in each of the chicken’s gametes? • How many chromosomes will be in each somatic cell of the chicken’s offspring? • How many chromosomes are in a “set” • Which came first…chicken or egg?
    7. 7. http://www.youtube.com/watch?v=m73i1Zk8EA0&feature=related
    8. 8. How many chromosomes are shown in this diagram? How many chromatids are shown?
    9. 9. on ati g lon e of e on Z a pic A Compare the number of cells in interphase, prophase, metaphase, anaphase or telophase in these two areas. Explain differences. m ste er i lm
    10. 10. Yeast Life Cycle
    11. 11. Budding Pattern
    12. 12. Yeast Mating Types
    13. 13. Uncontrolled Growth
    14. 14. Angiogenesis
    15. 15. Apoptosis
    16. 16. “Immortal Cells”
    17. 17. Telomerase
    18. 18. Metastasis
    19. 19. Immune System
    20. 20. What would happen if you performed this experiment with cancer cells?
    21. 21. Henrietta Lacks
    22. 22. HeLa cells
    23. 23. Stem Cell Stem Cell video
    24. 24. Stem Cell Sources
    25. 25. Embryonic Stem Cells (ES)
    26. 26. In Vitro Fertilization Louise Brown – Birthday 1978
    27. 27. Nuclear Transfer
    28. 28. Adult Stem Cells
    29. 29. iPS
    30. 30. IPS http://www.youtube.com/watch?v=fGNchPdlaGU&NR=1&feature=fvwp http://www.youtube.com/watch?v=cPvidAvzmx0&feature=related
    31. 31. STAP cells Haruko Obokata.
    32. 32. Controversial therapy.Mitochondrial DNA replacement could help carriers of severe disease have healthy children. G Vogel Science 2014;343:827-828 Published by AAAS
    33. 33. Meiosis Honors Biology
    34. 34. Aneuploidy Article Honors Biology
    35. 35. General Background Questions: • What is the genome, transcriptome and • the proteome? What is aneuploidy?
    36. 36. Experiment Questions: • What was the “conundrum” they identified • in the Introduction? What are the two experimental questions?
    37. 37. Meiosis Question: • Diagram why meiosis with odd ploidy (3N or 5N) would produce aneuploids.
    38. 38. Key Findings • What are key findings from: ab, ef, and gh?
    39. 39. A16 Why is strain A16 a good strain to focus on for experimental question?
    40. 40. ATR1 • What are: C• some XIII, ATR1, 4-NQO, and Strain A16? What is their relationship?
    41. 41. Proteome & Transcriptome: Gene dosage effect or dosage compensation Aneuploidy has global and complex effects on both the transcriptome and proteome levels, and that an increase in stress gene expression is not an obligate . property of aneuploidy strains

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