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Breast Cancer, New Horizons, Current Controversies

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  • 1. E a r n u p t o 19 A M A PR A C at e g ory 1 C r e di t s ™BR EAST CANCERNEW HORIZONSCURRENTCONTROV ERSIESJuly 12 – 14, 2012Boston Marriott Long WharfBoston, MassachusettsDirectors:Harold J. Burstein, MD, PhDJudy E. Garber, MD, MPHBarbara L. Smith, MD, PhDEric P. Winer, MD Offered by: Harvard Medical School Department of Continuing Education
  • 2. Breast Cancer | New Horizons | Current ControversiesJuly 12 – 14, 2012Boston Marriott Long Wharf | Boston, MassachusettsGreetings!We invite you to attend the 2012 Breast Cancer: New Horizons | Current Controversies three-day course jointly sponsored by theHarvard Medical School, Dana-Farber/Brigham and Women’s Cancer Center and Massachusetts General Hospital Cancer Center.This is our 10th year presenting this course, which annually attracts 350–400 oncology clinicians from around the world. Since theinception of this course, we have prioritized the quality of our faculty and worked to optimize the education content, presentation andrelevance to practice. During the last course 96% of our learners told us the course provided the most up-to-date information that couldbe translated into their practices.We’ve worked hard to bring you a relevant and useful curriculum and incorporated many suggestions from attendees of the previouscourse. We want to provide you with the best environment in which to learn about evidence based current practices, guidelines,controversies and treatments.This year’s curriculum will address six key learning objectives:• Recognize the molecular heterogeneity of breast cancer and therapeutic implications of HER2+, Triple Negative and ER+ disease.• Assess genetic and other personal risk factors for breast cancer and their impact on prevention. • Apply current approaches to prevention and survivorship to improve outcomes and quality of life for individuals with breast cancer or at increased risk.• Analyze challenging clinical cases in the adjuvant and metastatic breast cancer settings through different professional perspectives as they impact clinical practice.• Evaluate clinical trial results on multiple aspects of breast cancer for their potential impact on diagnosis, management and treatment.• Apply advances in breast cancer early detection, local therapy and treatment for patients with breast cancer or individuals at increased risk.Additionally, there will be several opportunities for specialized learning and personal interactions between faculty and learners.The hotel we’ve partnered with will provide learners the benefit of a “campus-like” experience in the heart of Boston, convenientlylocated steps from desirable dining and sight seeing destinations. The new completely renovated Boston Marriott Long Wharf offers aspecial rate of $249 per night for our course attendees.We think you will find this course to be a unique and valuable learning experience. Please register early as seats are limited and thecourse fills up quickly. We hope you will join us this July. Best,Harold J. Burstein, MD, PhDDana-Farber Cancer InstituteJudy E. Garber, MD, MPHDana-Farber Cancer InstituteBarbara L. Smith, MD, PhDMassachusetts General Hospital Cancer CenterEric P. Winer, MDDana-Farber Cancer Institute
  • 3. Course Description 2012 Highlights:Breast Cancer: New Horizons | CurrentControversies is an in-depth course which • Seven panel discussions with Q & Acovers the full scope of breast cancer care • 2012 ASCO highlightsfrom the pathogenesis of disease to theeconomics of providing breast health care. • Three case discussions on challenging multidisciplinary topicsRevolutionary advances in cell biology,genetics, neo-adjuvant treatment strategies • Meet the Professor session specific to allied health professionalsand surgical techniques offer new options for • New this year! Earn ABIM Maintenance of Certification creditsdiagnosing, treating, and conquering breastcancer but lead to recognition of knowledge • One special session for Pain Management CME creditand competence gaps for our target audience. • Centrally located within walking distance to Boston’s historic sitesThe primary goal of this course is toenhance the core competencies of health • Earn up to 19 AMA PRA Category 1 Credits™care professionals caring for breast cancerpatients by helping them to appropriatelyintegrate evidence-based information into ACCREDITATION Boston, MA 02241-7476. Telephone or faxtheir practices in order to reduce the gaps The Harvard Medical School is accredited registration is not accepted. Registration withand disparities in breast cancer screening, by the Accreditation Council for Continuing cash payment is not permitted. Upon receipt ofdiagnosis, treatment and monitoring. Medical Education to provide continuing your paid registration an email confirmationThis course offers a rare gathering of medical education for physicians. from the HMS-DCE office will be sent to you. Beclinical experts in medical, surgical, and The Harvard Medical School designates this sure to include an email address that you checkradiation oncology who will emphasize a live activity for a maximum of 19 AMA PRA frequently. Your email address is used for criticalmultidisciplinary approach to translating information, including registration confirmation, Category 1 Credits™. Physicians should claimscientific knowledge into practical applications evaluation, and certificate. only the credit commensurate with the extentin medicine. of their participation in the activity. INQUIRIESTeaching to Practice. This course providesample opportunity for learners to translate Nursing continuing education hours have been By phone 617-384-8600, Monday–Friday,content of the session into improvement in requested. 10 am to 4 pm (EST) or by email at:competence, knowledge and post-course Dana-Farber Cancer Institute is an approved hms-cme@hms.harvard.edu.performance. Attendees will engage faculty provider of continuing nursing education by ONLINE INFORMATIONwith thoughtful questions which will the Massachusetts Association of Registered To register or view activity information online,encourage discussion and critical thinking Nurses, Inc., and accredited approver by the visit: www.cme.hms.harvard.edu/courses/required to integrate the knowledge gained American Nurses Credentialing Centersinto clinical practice changes. Case review breastcancer. To ensure proper registration, Commission on Accreditation. please add the first three characters ofand small group discussions also provide anopportunity for learners to develop strategies ACGME COMPETENCIES the source code found at the bottom of thethey can apply in practice. This course is designed to meet one or more registration form.Learning Objectives of the following Accreditation Council of DISCLOSURE POLICYUpon completion of this course, participants Graduate Medical Education competencies: Harvard Medical School (HMS) adheres towill be able to: • Patient care all ACCME Essential Areas, Standards, and • Medical knowledge Policies. It is HMS’s policy that those who• Recognize the molecular heterogeneity of • Practice-based learning and improvements breast cancer and therapeutic implications have influenced the content of a CME activity • Interpersonal and communication skills (e.g., planners, faculty, authors, reviewers, of HER2+, Triple Negative and ER+ disease. • Professionalism• Assess genetic and other personal risk and others) disclose all relevant financial • Systems-based practice relationships with commercial entities so that factors for breast cancer and their impact on prevention. REGISTRATION INFORMATION HMS may identify and resolve any conflicts of• Apply current approaches to prevention Early Full Tuition (Registrations interest prior to the activity. These disclosures and survivorship to improve outcomes and postmarked on or before May 31, 2012) will be provided in the activity materials along quality of life for individuals with breast Physicians: $525 (USD) with disclosure of any commercial support cancer or at increased risk. Residents/Fellows in Training, received for the activity. Additionally, faculty• Analyze challenging clinical cases in the and Allied Health Professionals: $425 (USD) members have been instructed to disclose adjuvant and metastatic breast cancer Nurse Practitioners, Nurses: $425 (USD) any limitations of data and unlabeled or settings through different professional investigational uses of products during their Full Tuition (Registrations perspectives as they impact clinical presentations. postmarked after May 31, 2012) practice. Physicians: $600 (USD) REFUND POLICY• Evaluate clinical trial results on multiple aspects of breast cancer for their potential Harvard Affiliate Physicians: $525 (USD) A handling fee of $60 is deducted for impact on diagnosis, management and Residents/Fellows in Training, cancellation. Refund requests must be received treatment. and Allied Health Professionals: $500 (USD) by postal mail, email, or fax one week prior• Apply advances in breast cancer early Harvard Affiliate Residents/Fellows, to this activity. No refunds will be made detection, local therapy and treatment for and Allied Health Professionals: $425 (USD) thereafter. patients with breast cancer or individuals Nurse Practitioners, Nurses: $500 (USD) COURSE LOCATION at increased risk. Registration by credit card (VISA or All sessions for this course will beTarget audience MasterCard) can be made at: www.cme. held at Boston Marriott Long Wharf,Medical oncologists, surgical oncologists, ra- hms.harvard.edu/courses/breastcancer. 296 State Street, Boston, MA 02109diation oncologists, breast surgeons, internists, Registration by check (draft on a United States (Telephone: 617-227-0800)physicians assistants, nurse practitioners, bank), please make payable to Harvard Medicaloncology nurses, breast cancer advocates and School and mail with registration form toothers interested in the care of women with Harvard Medical School—Departmentbreast cancer. of Continuing Education, PO Box 417476,
  • 4. C OUR SE S C H E DU L E | T H UR SDAY, J U LY 1 2 , 2 01 27:15 am Registration and Continental Breakfast8:00 am Welcoming Remarks Eric P. Winer, MD, Dana-Farber/Brigham and Women’s Cancer Center SESSION I: What to Watch in Breast Cancer Chair: Lawrence Shulman, MD Early Detection and Treatment Dana-Farber/Brigham and Women’s Cancer Center8:10 am Radiation 101 Jennifer Bellon, MD, Dana-Farber, Brigham and Women’s Cancer Center8:30 am What to Watch for in Pathology Andrea Richardson, MD, PhD, Dana-Farber/Brigham and Women’s Cancer Center8:50 am What to Watch for in Reconstructive and Plastic Surgery Amy Colwell, MD, Massachusetts General Hospital Cancer Center 9:10 am Session 1 Questions and Discussion9:25 am Break9:40 am Targets to Watch in Breast Cancer Jose Baselga, MD, PhD, Massachusetts General Hospital Cancer Center10:00 am Adjuvant Chemotherapy for ER+ Cancers Lawrence Shulman, MD, Dana-Farber/Brigham and Women’s Cancer Center10:20 am Session 1 Questions and Discussion All LECTURE & challenging CASE DISCUSSION10:40 am Inflammatory Breast Cancer Beth Overmoyer, MD, Dana-Farber/Brigham and Women’s Cancer Center11:05 am Case Discussion: Locally Advanced and Inflammatory Chair: Craig Bunnell, MD Breast Cancer Dana-Farber/Brigham and Women’s Cancer Center Panel: TBD12:05 pm Lunch (on your own) SCHLAGER LECTURE1:05 pm Symptom Assessment: Who is the Best Judge? Lesley Fallowfield, PhD, Brighton and Sussex Medical School, UK SESSION II: Prevention Chair: Ann Partidge, MD, MPH Dana-Farber/Brigham and Women’s Cancer Center1:40 pm Mammographic Density: A Risk Marker? Celine Vachon, PhD, Mayo Clinic2:00 pm Surgical Approaches to Risk Reduction: Who, When, Why and How? Barbara Smith, MD, PhD, Massachusetts General Hospital Cancer Center2:20 pm Future Directions in Prevention Powel Brown, MD, PhD, MD Anderson Cancer Center2:40 pm Session II Questions and Discussion All2:55 pm Break SESSION III: Survivorship Chair: Ann Partridge, MD, MPH Dana-Farber/Brigham and Women’s Cancer Center3:10 pm Complications and Late Effects of Local Therapy Laura Dominici, MD, Dana-Farber/Brigham and Women’s Cancer Center 3:30 pm Complications of Systemic Therapy Patricia Ganz, MD, University of California, Los Angeles3:50 pm Promoting Better Care for Survivors Ann Partridge, MD, MPH, Dana-Farber/Brigham and Women’s Cancer Center4:10 pm Session III Questions and Discussion All SPECIAL SESSIONS4:30 pm Meet the Professor Sessions Sessions will be specific to professional groups TBD5:30 pm Pain Management Session – Optional Janet Abrahm, MD, Dana-Farber/Brigham and Women’s Cancer Center6:30 pm Adjourn for the Day
  • 5. C OUR SE S C H E DU L E | F r iday, J u ly 1 3 , 2 01 27:15 am Continental Breakfast LECTURE8:00 am Healthcare Disparities and Breast Cancer Michael Hassett, MD, MPH, Dana-Farber/Brigham and Women’s Cancer Center SESSION IV: Genetic and Personal Risk Factors Chair: Stuart Schnitt, MD for Breast Cancer Beth Israel Deaconess Medical Center8:35 am Using Genetic Information in Patient Care Judy Garber, MD, MPH, Dana-Farber/Brigham and Women’s Cancer Center8:55 am Alcohol, Smoking and Other Environmental Factors Wendy Chen, MD, MPH, Dana-Farber/Brigham and Women’s Cancer Center9:10 am Obesity and Exercise Jennifer Ligibel, MD, Dana-Farber/Brigham and Women’s Cancer Center9:25 am Premalignant Lesions Stuart Schnitt, MD, Beth Israel Deaconess Medical Center9:45 am Session IV Questions and Discussion All10:05 am Break SESSION V: HER2+ Breast Cancer Chair: Ian Krop, MD, PhD10:20 am The Biology of HER2+ Breast Cancer for the Clinician Carlos Arteaga, MD, PhD, Vanderbilt-Ingram Cancer Center10:45 am Adjuvant Therapy Eric Winer, MD, Dana-Farber/Brigham and Women’s Cancer Center11:10 am Standard and Investigational Approaches to HER2+ Metastatic Breast Cancer Ian Krop, MD, PhD, Dana-Farber/Brigham and Women’s Cancer Center11:30 am Brain Mets: HER2+ and Beyond Nancy U. Lin, MD, Dana-Farber/Brigham and Women’s Cancer Center11:50 am Session V Questions and Discussion All12:10 pm Lunch / Meet the Professor (sign up in advance, TBN) SESSION VI: Triple Negative Disease Chair: Judy Garber, MD, MPH Dana-Farber/Brigham and Women’s Cancer Center1:10 pm Biology, Heterogeneity and Natural History of Triple Negative Breast Cancer Lisa Carey, MD, University of North Carolina, Chapel Hill1:30 pm Treatment Options for Patients with Triple Negative Metastatic Disease Steven Isakoff, MD, PhD, Massachusetts General Hospital Cancer Center1:50 pm Exploiting DNA Repair Deficiencies in Treating Triple Negative Breast Cancer Daniel Silver, MD, PhD, Dana-Farber/Brigham and Women’s Cancer Center2:10 pm Session VI Questions and Discussion2:25 pm Break2:40 pm Perception and Reality of Triple Negative Disease: Psychosocial Aspects of High Risk Settings Lesley Fallowfield, PhD, Brighton and Sussex Medical School, UK3:00 pm Management of Refractory Breast Cancer: Update on Novel Chemotherapy and Anti-Angiogenic Approaches Erica Mayer, MD, MPH, Dana-Farber/Brigham and Women’s Cancer Center3:20 pm Relevant Endpoints in Clinical Trials and Benefit Needed for FDA Approval Cliff Hudis, MD, Memorial Sloan Kettering Cancer Center3:40 pm Session VI Questions and Discussion All LECTURE4:00 pm The Problem with Late Recurrence in ER+ Disease Mitch Dowsett, PhD, BSc, Royal Marsden Hospital and Institute of Cancer Research, UK
  • 6. C OUR SE S C H E DU L E | F r iday, J u ly 1 3 , 2 01 2 - cont inued CASE DISCUSSION4:30 pm Metastatic Case Discussion Chair: Harold Burstein, MD, Dana-Farber/Brigham and Women’s Cancer Center Panel: TBD5:30 pm ABIM Maintenance of Certification (MOC) Special Session (optional – sign up in advance)6:30 pm Adjourn for the Day C OUR SE S C H E DU L E | S at u r day, J u ly 14 , 2 01 27:15 am Continental Breakfast CASE DISCUSSION8:00 am Challenging Cases in the Adjuvant Setting Chair: Harold Burstein, MD, Dana-Farber/Brigham and Women’s Cancer Center Panel: TBD SESSION VII: ADVANCES IN LOCAL THERAPY Chair: Barbara L. Smith, MD, PhD Massachusetts General Hospital Cancer Center9:00 am Post-Mastectomy Radiation: Where Are We in 2012? Jay Harris, MD, Dana-Farber/Brigham and Women’s Cancer Center9:20 am New Approaches to Minimize Toxicity from Radiation Frank Vicini, MD, FACR, Michigan Healthcare Professionals / 21st Century Oncology9:40 am DCIS: Who Doesnt Need Radiation? Beryl McCormick, MD, FACR, Memorial Sloan Kettering Cancer Center10:00 am Session VII Questions and Discussion10:15 am Break10:25 am Bilateral Mastectomies: What Are the Real Indications? Michelle Specht, MD, Massachusetts General Hospital Cancer Center10:45 am Evaluating the Axila in Invasive and Non-Invasive Disease Armando E. Giuliano, MD, FACS, FRCSEd, Cedars-Sinai Medical Center11:05 am Surgical Management after Preoperative Therapy Mehra Golshan, MD, FACS, Dana-Farber/Brigham and Women’s Cancer Center11:25 am Session VII Questions and Discussion11:40 am Highlights from ASCO 2012 Harold Burstein, MD, Dana-Farber/Brigham and Women’s Cancer Center12:40 pm Concluding Remarks and Adjourn12:45 pm Box Lunch (sign up in advance) Program changes/substitutions may be made without notice.
  • 7. Course number is 321279Br east Cancer R EGISTRATION IN FOR M ATIONNew Horizons BR EAST CANCER | CURR ENT CONTROVERSIES | NEW HORIZONS | July 12 – 14, 2012Cur r ent ControversiesJuly 12 – 14, 2012 You are encouraged to register early as space is limited. For additional course information, including complete faculty biographies, pleaseBoston Marriott Long Wharf visit www.cme.hms.harvard.edu/courses/breastcancer.296 State Street Early Full Tuition (Registrations postmarked on or before May 31, 2012)Boston, MA 02109 • Physicians: $525 (USD)617-227-0800 • Residents/Fellows in Training, and Allied Health Professionals: $425 (USD) • Nurse Practitioners, Nurses: $425 (USD) Full Tuition (Registrations postmarked after May 31, 2012) • Physicians: $600 (USD) • Harvard Affiliate Physicians: $525 (USD) • Residents/Fellows in Training, and Allied Health Professionals: $500 (USD) • Harvard Affiliate Residents/Fellows in Training, and Allied Health Professionals: $425 (USD) • Nurse Practitioners, Nurses: $500 (USD) Print Name Clearly – All Fields RequiredThe beautifully renovated BostonMarriott Long Wharf offers an ideal Full Namedowntown location, spectacular First Middle Initial Lastwaterfront views and top-notch service.Rooms are limited, so please book early.ACCOMMODATIONS/TRAVEL Mailing Address Street City State Zip CodeA limited number of rooms have beenreserved at Boston Marriott Long Wharf(Telephone: 617-227-0800) until June 20, Daytime Phone ( ) Fax Number ( )2012. Please identify yourself as a “BreastCancer Course” attendee and provide the PLEASE NOTE: Your email address is used for critical information about the course including: registration confirmation, course evaluation, and certificate. Please be sure to include an email address you check daily or frequently.Group Code to receive the reduced roomrate of $249 per night Single/Double.Hotel arrangements can also be madeonline at: http://www.marriott.com/ Email Address • Please check if you wish to be excluded from receiving email notices of future hms-dce programs.hotels/travel/boslw-boston-marriott-long-wharf/. Enter Group Code: bccbccafor online reservations. Please do not Profession Degreepurchase non-refundable airline ticket(s)until you have received an email from ouroffice confirming your paid registration.For airline reservations contact the HMS Primary Specialty (Physicians Only) Board Certified: • Yes • NoTravel Desk toll free 1-877-4-HARVMD(1-877-442-7863) Monday–Friday 9 am–8 pm(EST). From outside the U.S., Canada, and Professional School Attended (Physicians Only):Virgin Islands, please call 617-559-3764. • Harvard Medical School • U.S. Medical School • International Year of Graduation • Please indicate if you will attend these optional sessions. See details on the course agenda. A. Optional Pain Management session: July 12, 2012, at 5:30 pm. B. Optional Meet the Professor session: July 13, 2012, at 12:10 pm (during lunch). C. ABIM Maintenance of Certification session: July 13, 2012, at 5:30 pm. If you require special assistance (wheelchair, auxiliary aids) or special dietary requirements, please indicate and we will contact you. • Yes  Online Registrants – add the first three characters of the Source Code found here ➞ Source Code: W WEB0516 E ✃