Photographs courtesy of the Greater Boston Convention & Visitors Bureau
First Preliminary Program
Transforming Reproductiv...
2
Boston is more vibrant than ever! New green spaces are sprouting up all over, and a revitalized waterfront has added to ...
NIGHT MUSEUMAT
THE
OF SCIENCE
BOSTON • MA
MIX, MINGLE
& BE BLINDED
BY SCIENCE!
Wednesday, October 16, 2013
7:00 pm - 9:00 ...
Exciting events coming
your way in 2013!
Make plans now to participate in the
4th annual ASRM 5k Run &
1 mile Walk
Monday ...
5
IFFS/ASRM WELCOME
WELCOME TO BOSTON . . . . . . . . . . . 2
MUSEUM NIGHT . . . . . . . . . . . . . . . . 3
OPENING CEREM...
6
IFFS/ASRM CONJOINT MEETING
PROGRAM PLANNING COMMITTEE
IFFS SCIENTIFIC COMMITTEE
Basil Tarlatzis (Greece), Chair
Joe Leig...
7
ASRM OFFICERS
Linda C. Giudice, M.D., Ph.D., President
Richard H. Reindollar, M.D., President-Elect
Dolores J. Lamb, Ph....
IFFS/ASRM Annual Meeting Policies and Disclaimers
CANCELLATION POLICY
The International Federation of Fertility Societies ...
9
Registration & Meeting Information
8 Register online @ www.asrm.org and receive immediate confirmation!
! On-site in Bos...
10
Individual Registration for the 2013 IFFS/ASRM Annual Meeting
opens April 30, 2012.
Group Registration for the 2013 IFF...
11
Registration Information
POSTGRADUATE COURSE REGISTRATION FEES
	 Early Bird Advanced Onsite
		 By	 By After
7/11/2013 9...
12
Housing Information
Book in the IFFS/ASRM Housing Block and
SAVE $50 off Registration fees!
To book housing for the 201...
13
Boston Hotel Map2013IFFS/ASRMCONJOINTMEETING
14
Disclosure Statements/Conflict of Interest Policy
2013 IFFS/ASRM Conflict of Interest
Policy for Invited SpeakersHonora...
15
46TH
ANNUAL
POSTGRADUATE
PROGRAM
COMMITTEE
CHAIR
Anuja Dokras, M.D., Ph.D.
CO-CHAIR
Lisa M. Halvorson, M.D., Ph.D.
COOR...
16
46TH
ANNUAL POSTGRADUATE PROGRAM
COMPLICATIONS OF ART: IN SEARCH OF A HAPPY ENDING
Course PG3 (Saturday)
Developed in C...
17
46TH
ANNUAL POSTGRADUATE PROGRAM
Developed in Cooperation with the Society of Reproductive Biologists and Technologists...
18
46TH
ANNUAL POSTGRADUATE PROGRAM
BRIDGING THE GAP BETWEEN SCIENCE AND CLINICAL CARE IN
ENDOMETRIOSIS-RELATED INFERTILIT...
19
ACGME Competency
Patient care
LEARNING OBJECTIVES
At the conclusion of this course, participants should be able to:
1. ...
20
THE ART OF GENETICS: REPRODUCTIVE GENETICS IN THE ART SETTING
Course PG9 (Saturday)
46TH
ANNUAL POSTGRADUATE PROGRAM
De...
21
46TH
ANNUAL POSTGRADUATE PROGRAM
Developed in Cooperation with the Society for Assisted Reproductive Technology
FACULTY...
22
PCOS: CARING FOR A WOMAN OVER HER LIFETIME
Course PG13 (Sunday)
46TH
ANNUAL POSTGRADUATE PROGRAM
Developed in Cooperati...
23
46TH
ANNUAL POSTGRADUATE PROGRAM
LEARNING OBJECTIVES
At the conclusion of this course, participants should be able to:
...
24
46TH
ANNUAL POSTGRADUATE PROGRAM
ACGME Competency
Patient care
LEARNING OBJECTIVES
At the conclusion of this course, pa...
25
46TH
ANNUAL POSTGRADUATE PROGRAM
ACGME Competency
Medical knowledge
LEARNING OBJECTIVES
At the conclusion of this cours...
26
GLOBAL FAMILY PLANNING: THE KEY TO ACHIEVING MILLENNIUM DEVELOPMENT GOALS
Course PG20 (Sunday)
46TH
ANNUAL POSTGRADUATE...
27
46TH
ANNUAL POSTGRADUATE PROGRAM
LEARNING OBJECTIVES
At the conclusion of this course, participants should be able to:
...
28
46TH
ANNUAL POSTGRADUATE PROGRAM
TRAINING PEOPLE IN LOW-COST INFERTILITY AND ART TREATMENT
Course PG23 (Sunday)
Develop...
29
46TH
ANNUAL POSTGRADUATE PROGRAM
PGD IMPACT ON ART EFFICIENCY WITH INTRODUCTION OF
MICROARRAY TECHNOLOGY FOR 24 CHROMOS...
30
46TH
ANNUAL POSTGRADUATE PROGRAM
The decision to offer a particular management strategy is dictated by the patient’s cl...
31
IFFS/ASRM 2013 Scientific Program
Needs Assessment and Description
The field of reproductive medicine is evolving rapid...
69th American Society for Reproductive Medicine (ASRM) Annual Meeting 2013
69th American Society for Reproductive Medicine (ASRM) Annual Meeting 2013
69th American Society for Reproductive Medicine (ASRM) Annual Meeting 2013
69th American Society for Reproductive Medicine (ASRM) Annual Meeting 2013
69th American Society for Reproductive Medicine (ASRM) Annual Meeting 2013
69th American Society for Reproductive Medicine (ASRM) Annual Meeting 2013
69th American Society for Reproductive Medicine (ASRM) Annual Meeting 2013
69th American Society for Reproductive Medicine (ASRM) Annual Meeting 2013
69th American Society for Reproductive Medicine (ASRM) Annual Meeting 2013
69th American Society for Reproductive Medicine (ASRM) Annual Meeting 2013
69th American Society for Reproductive Medicine (ASRM) Annual Meeting 2013
69th American Society for Reproductive Medicine (ASRM) Annual Meeting 2013
69th American Society for Reproductive Medicine (ASRM) Annual Meeting 2013
69th American Society for Reproductive Medicine (ASRM) Annual Meeting 2013
69th American Society for Reproductive Medicine (ASRM) Annual Meeting 2013
69th American Society for Reproductive Medicine (ASRM) Annual Meeting 2013
69th American Society for Reproductive Medicine (ASRM) Annual Meeting 2013
69th American Society for Reproductive Medicine (ASRM) Annual Meeting 2013
69th American Society for Reproductive Medicine (ASRM) Annual Meeting 2013
69th American Society for Reproductive Medicine (ASRM) Annual Meeting 2013
69th American Society for Reproductive Medicine (ASRM) Annual Meeting 2013
69th American Society for Reproductive Medicine (ASRM) Annual Meeting 2013
69th American Society for Reproductive Medicine (ASRM) Annual Meeting 2013
69th American Society for Reproductive Medicine (ASRM) Annual Meeting 2013
69th American Society for Reproductive Medicine (ASRM) Annual Meeting 2013
69th American Society for Reproductive Medicine (ASRM) Annual Meeting 2013
69th American Society for Reproductive Medicine (ASRM) Annual Meeting 2013
69th American Society for Reproductive Medicine (ASRM) Annual Meeting 2013
69th American Society for Reproductive Medicine (ASRM) Annual Meeting 2013
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69th American Society for Reproductive Medicine (ASRM) Annual Meeting 2013

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69th American Society for Reproductive Medicine (ASRM) Annual Meeting 2013

  1. 1. Photographs courtesy of the Greater Boston Convention & Visitors Bureau First Preliminary Program Transforming Reproductive Medicine Worldwide OCTOBER 12 - 17, 2013
  2. 2. 2 Boston is more vibrant than ever! New green spaces are sprouting up all over, and a revitalized waterfront has added to the city’s already dynamic downtown neighborhoods. These developments are thanks in part to the city’s Big Dig project, which is now complete. Additionally, Logan International Airport’s recent upgrades are making it easier than ever to get in and out of the city, and new sights and attractions are providing more for everyone to see and do while in Boston. Boston’s Waterfront has become an idyllic setting for watching sailboats and ferries glide in and out of the harbor and an excellent destination for classic New England seafood restaurants. Boston’s Rose Kennedy Greenway consists of three parks and a total of 30 acres of beautiful, tree-lined corridors. Visitors will find more than 900 trees, public art, fountains and great places for exercise or contemplation. In the works for the Greenway are the Boston Museum Project, which will focus on the last 200 years of Boston history, and The New Center for Arts and Culture, which will present a variety of dance performances, films, music, lectures and art. The new 44-mile Boston HarborWalk includes the downtown Boston waterfront and continues north and south along wharves, piers, museums, historic forts, bridges, beaches and shoreline from Chelsea Creek to the Neponset River. The HarborWalk also connects to new and existing trails: The Freedom Trail, the new Walk To The Sea, the Emerald Necklace, the Charles River Esplanade, the Rose Kennedy Greenway, and in the future, the South Bay Harbor Trail. The one-mile Walk To The Sea is a Beacon Hill-to-the-waterfront marked walkway. Beginning at the Massachusetts State House, the visitor learns about the four centuries of maritime history from Beacon Hill to State Street to the 18th century Long Wharf. Constructed from dirt excavated from the Big Dig’s extensive network of tunnels, Spectacle Island in Boston Harbor features a marina, visitor center, sandy beaches and five miles of walking trails that lead to the crest of a 157-foot hill offering panoramic views of the harbor and the city. Visitors are welcome from dawn to dusk during the summer months. Passenger ferry service is available from Boston. Chinatown Park, a beautiful parcel of land in Chinatown, is populated by bamboo trees, azaleas, stones and a peaceful stream. The new park is situated at the south end of the Greenway and is the perfect place to experience the Chinese ideal of Feng Shui, followed by an authentic dim sum meal. History around every corner, and so much more! Boston’s rich art, music and dance institutions, theatre and cultural attractions, distinguished dining and nightlife venues, world-class shopping and championship sports teams make it a unique place for travelers to visit. The city’s downtown neighborhoods offer endless unique experiences and its proximity to other must-see sites all around New England make it one of the country’s most diverse and exciting locales. Here in Boston, visitors are never at a loss for things to do. The many museums, concert halls, theaters and nightclubs are always showcasing great talent and events. There’s the internationally acclaimed Museum of Fine Arts, the Museum of Science, New England Aquarium and the John F. Kennedy Presidential Library & Museum. Beyond the museum scene, there’s the world-famous Boston Symphony Orchestra and Boston Pops, local and pre-Broadway theater, distinctive dining, endless opportunities for shopping and sightseeing, and a year-round calendar of special events and celebrations. Boston is home to a grand tradition of sporting excellence. This is where storied franchises such as the Red Sox (2004 and 2007 World Series Champions), the Celtics (2008 World Champions), the Bruins, and the New England Patriots (2001, 2003 and 2004 Super Bowl champions) all play their games. Visiting sports fans can’t help getting caught up in the enthusiasm. In addition to everything within the city limits, some of Massachusetts’ most scenic and historic towns are just a short distance from the city center. There are sights to see at every turn. Cambridge is often referred to as “Boston’s Left Bank” with an atmosphere — and attitude — all its own. It’s the spirited, slightly mischievous side of Boston, just a bridge away on the other side of the Charles River. Packed with youthful vitality and international flair, it’s a city where Old World meets New Age in a mesmerizing blend of history and technology. As the East Coast’s leading hub for high tech and biotech, Cambridge has a creative, entrepreneurial spirit. It is also the birthplace of higher education in America. Harvard College was founded in 1636, and across town, Massachusetts Institute of Technology (MIT) is known as the epicenter of cyberculture. Both universities house renowned museum collections and tours that are open to the public. As a captivating, offbeat alternative to Boston’s urban center, the “squares” of Cambridge are charming neighborhoods rich in eclectic shopping, theaters, museums and historic sites. Cambridge also offers a tantalizing array of dining options for the visitor with a sophisticated palate. Welcome to Boston! Information on Boston provided by the Greater Boston Convention and Visitors Bureau 2
  3. 3. NIGHT MUSEUMAT THE OF SCIENCE BOSTON • MA MIX, MINGLE & BE BLINDED BY SCIENCE! Wednesday, October 16, 2013 7:00 pm - 9:00 pm Tickets $125 Explore Boston's Museum of Science Heavy hors d'oeuvres • Beer • Wine Transportation will be provided.
  4. 4. Exciting events coming your way in 2013! Make plans now to participate in the 4th annual ASRM 5k Run & 1 mile Walk Monday • October 14, 2013 Boston, MA Get a step ahead!
  5. 5. 5 IFFS/ASRM WELCOME WELCOME TO BOSTON . . . . . . . . . . . 2 MUSEUM NIGHT . . . . . . . . . . . . . . . . 3 OPENING CEREMONY & NETWORKING EVENT . . . . . . . . . . . . . . 4 ASRM 5K RUN INFORMATION . . . . . . 4 IFFS/ASRM WELCOME . . . . . . . . . . . . 5 IFFS/ASRM CONJOINT MEETING PROGRAM PLANNING COMMITTEE . . . . . . . . . . . 6 IFFS OFFICERS AND BOARD OF DIRECTORS . . . . . . . . . . . 7 ASRM OFFICERS AND BOARD OF DIRECTORS . . . . . . . . . . . 7 IFFS/ASRM ANNUAL MEETING POLICIES & DISCLAIMERS . . . . . . . . . 8 REGISTRATION & MEETING INFORMATION . . . . . . . . . . . . . . . . 9-11 HOUSING INFORMATION . . . . . . 12-13 DISCLOSURE STATEMENTS & CONFLICT OF INTEREST POLICY . ..14 POSTGRADUATE PROGRAM . . . . . . . . . . . . . . . . . . 15-30 FUTURE ASRM MEETING DATES . . . 30 NEEDS ASSESSMENT & LEARNING OBJECTIVES . . . . . . . . . 31 IFFS/ASRM 2013 CONJOINT MEETING GRID . . . . . . . 32 SCIENTIFIC PROGRAM DAILY SCHEDULE . . . . . . . . . . . . . 33-38 MENOPAUSE DAY . . . . . . . . . . . . . . . 39 SURGERY DAY . . . . . . . . . . . . . . . . . . 40 CONTRACEPTION DAY . . . . . . . . . . . 41 SPOUSE/GUEST PROGRAM . . . . . . . 41 PLENARY SESSIONS . . . . . . . . . . 42-43 TRILOGIES . . . . . . . . . . . . . . . . . . . 44-49 ASRM MORNING SYMPOSIA . . . . . . . 50 ASRM AFTERNOON SYMPOSIA . . . . . . . . . . . . . . . . . . 51-52 INTERACTIVE SESSIONS . . . . . . 53-56 SMRU MINI-SYMPOSIA . . . . . . . . . . . 56 VIDEO SESSIONS . . . . . . . . . . . . . . . 56 WRITE THE NEXT CHAPTER CONTRIBUTION OPPORTUNITIES . . 59 INSIDE Dear Colleagues, I write as President of the International Federation of Fertility Societies (IFFS) to invite you to our 21st World Congress to be held conjointly with the American Society for Reproductive Medicine (ASRM), one of our very senior member societies, in Boston on October 12-17, 2013. It is a pleasure for IFFS to thank Dr. Linda Giudice and the ASRM staff for their co-operation and help to IFFS over the past three years. Building on the strong foundation of the 2010 IFFS World Congress in Munich, our last Triennial Congress, features such as regional sessions and live surgery have been incorporated into the 2013 program. The Regional Sessions are planned and presented by IFFS member societies, most often in the language of their country. For those who are unfamiliar with IFFS, the Federation was founded in 1951 with an educational mission. Each year IFFS conducts workshops in selected cities in underdeveloped countries, sponsors a Symposium in its International Series on topics of regional concern, and every three years holds a World Congress. Today more than 70 national societies from around the globe are members of the Federation. Our 2013 Program Chair, Dr. Basil Tarlatzis, and his colleagues, have crafted an exciting program for Boston using the trilogy structure, the hallmark of past IFFS World Congresses. So mark October 12 -17, 2013, in all your diaries and electronic devices now - you will never, never know how good Boston is if you never, never go! Sincerely, Dr. David Healy, FRANZCOG, FRCOG, Ph.D. IFFS President 2010 -2013 David Healy, M.D., Ph.D. IFFS President 2010-2013 As President-elect of the American Society for Reproductive Medicine (President 2012-2013), I enthusiastically welcome you to the 69th Annual Meeting of the ASRM conjoint with the 21st Meeting of the International Federation of Fertility Societies (IFFS) in Boston, Massachusetts, October 12-17, 2013. Serdar Bulun and the ASRM Scientific Program Committee along with Basil Tarlatzis and the IFFS Scientific Committee have put together a phenomenal program, along with Anuja Dokras for the Postgraduate Program and Steven Palter for the Video Program. As a conjoint meeting, we have extended the program by one day to accommodate additional interactive poster sessions, the traditional IFFS trilogies, and regional meetings for our international societies. The theme of our conjoint meeting is “Transforming Reproductive Medicine Worldwide,” and we have planned plenary lectures by international luminaries addressing state-of-the-art issues in reproductive medicine and science. We shall continue to have roundtables, videos, interactive sessions, symposia, and the popular sessions focused on menopause and contraception. During the 2013 meeting, we also plan hands-on robotic and other surgical intensives, and to focus more broadly on global applications of infertility therapies and reproductive health in low resource settings. As a conjoint meeting, our U.S. and international members will join the membership of the IFFS in reaching out to specialists in reproductive medicine worldwide to learn from each other about issues that are unique in different parts of the world and those that are common to us all. This conjoint meeting provides an opportunity to learn the latest research in the oral and poster presentations and other venues. Our many special interest and professional groups within ASRM will be presenting data that can be considered by all. The Conjoint meeting of the IFFS/ASRM in Boston 2013 will provide an opportunity to learn, to see old friends, meet new friends, and see the world of reproductive medicine through a new lens. We are developing a social program for all in Boston, a vibrant city with great historical significance in the U.S. and globally. I look forward to seeing you in Boston in 2013, as we all participating in the process of “Transforming Reproductive Medicine Worldwide!” Sincerely, Linda C. Giudice, M.D., Ph.D. ASRM President 2012-2013 Linda C. Giudice, M.D., Ph.D. ASRM President 2012-2013
  6. 6. 6 IFFS/ASRM CONJOINT MEETING PROGRAM PLANNING COMMITTEE IFFS SCIENTIFIC COMMITTEE Basil Tarlatzis (Greece), Chair Joe Leigh Simpson (USA), President Elect Liselotte Mettler (Germany), 2010 Chair Local SC Linda Giudice (USA), 2013 Congress Chair Serdar Bulun (USA), 2013 Chair Local SC Dhiraj Gada (India), 2016 Congress Chair Narendra Malhotra (India), 2016 Chair Local SC Richard Kennedy (UK), Secretary General, ex officio member Paul Devroey (Belgium), Director of Medical Education, ex officio member David Healy, IFFS President IFFS SCIENTIFIC COMMITTEE MEMBER SOCIETIES Brazilian Society of Human Reproduction Artur Dzik British Fertility Society Sue Avery Finnish Gynecological Association Antti Perheentupa Japan Society of Reproductive Medicine Minoru Irahara Fertility Society of Australia Cynthia Farquhar Korean Society for Reproductive Medicine Seok Hyun Kim American Society for Reproductive Medicine Alan DeCherney (ex officio) American Society for Reproductive Medicine Andrew La Barbera (ex officio) American Society for Reproductive Medicine Robert Rebar (ex officio) ASRM SCIENTIFIC AND POSTGRADUATE PLANNING COMMITTEES Linda C. Giudice, M.D., M.S., M.Sc., Ph.D., ASRM President Serdar E. Bulun, M.D., Scientific Program Chair Lawrence C. Layman, M.D., Interactive Sessions Chair Kurt T. Barnhart, M.D., Roundtable Program Chair Anuja Dokras, M.D., Ph.D., Postgraduate Program Chair Lisa M. Halvorson, M.D., Postgraduate Program Co-Chair Bradley J. Van Voorhis, M.D., Postgraduate Program Coordinating Chair G. David Ball, Ph.D., Society for Assisted Reproductive Technology Program Chair Kurt T. Barnhart, M.D., Society for Reproductive Endocrinology and Infertility Program Chair Paul J. Turek, M.D., Society for Male Reproduction and Urology Program Chair Grace M. Janik, M.D., Society of Reproductive Surgeons Program Chair Nidhi Desai, J.D., Legal Professional Group Program Chair Claudia Pascale, Ph.D., Mental Health Professional Group Program Chair Deborah L. Jaffe, B.S.N., Nurses’ Professional Group Program Chair Thomas G. Turner, M.S., Society of Reproductive Biologists and Technologists Program Chair Joseph J. Travia, Jr., B.S., M.B.A., Association of Reproductive Managers Program Chair Catherine Racowsky, Ph.D., Ad Hoc Member Marcelle I. Cedars, M.D., Ad Hoc Member Robert E. Brannigan, M.D., Ad Hoc Member Robert W. Rebar, M.D., ASRM Executive Director Andrew R. La Barbera, Ph.D., H.C.L.D., ASRM Scientific Director C. Lee Hutchison, M.A., ASRM Scientific Program Coordinator Penelope Fenton, M.A., ASRM Postgraduate Program Coordinator ASRM VIDEO COMMITTEE Steven F. Palter, M.D., Chair Tien-cheng A. Chang, Ph.D. Tommaso Falcone, M.D. Emilio Fernandez, M.D. Antonio R. Gargiulo, M.D. Arik Kahane, M.D. Philip S. Li, M.D. Stephen R. Lindheim, M.D. Marius Meintjes, D.V.M., Ph.D. Dana A. Ohl, M.D. David L. Olive, M.D. Marc P. Portmann, M.T. Togas Tulandi, M.D. Paul J. Turek, M.D.
  7. 7. 7 ASRM OFFICERS Linda C. Giudice, M.D., Ph.D., President Richard H. Reindollar, M.D., President-Elect Dolores J. Lamb, Ph.D., H.C.L.D., Immediate Past President Roger A. Lobo, M.D., Past President Catherine Racowsky, Ph.D., H.C.L.D., Secretary Stuart S. Howards, M.D., Treasurer ASRM BOARD OF DIRECTORS AND THEIR MEMBER SOCIETIES Marc Fritz, M.D. Nancy Brackett, Ph.D. Marcelle I. Cedars, M.D. Christos Coutifaris, M.D., Ph.D. Roger A. Lobo, M.D. Dolores J. Lamb, Ph.D., H.C.L.D. Steven Nakajima, M.D. (SREI) Grace Janik, M.D. (SRS) Grace Centola, Ph.D., , H.C.L.D. (SMRU) Thomas Turner, Jr., E.L.D., M.S. (SRBT) David Ball, Ph.D., H.C.L.D. (SART) ASRM EXECUTIVE DIRECTOR Robert W. Rebar, M.D. ASRM SCIENTIFIC DIRECTOR Andrew R. La Barbera, Ph.D., H.C.L.D. IFFS OFFICERS AND BOARD OF DIRECTORS 2010 - 2013 IFFS OFFICERS David Healy (Australia), President Joe Leigh Simpson (USA), President Elect Richard Kennedy (UK), Secretary General Gabriel de Candolle (Switzerland), Assistant Secretary General Edgar Mocanu (Ireland), Treasurer Mauricio Abrao (Brazil), Assistant Treasurer Basil Tarlatzis (Greece), Past President Paul Devroey (Belgium), Director of Medical Education IFFS BOARD OF DIRECTORS AND THEIR MEMBER SOCIETIES American Society for Reproductive Medicine G. David Adamson 2007-2016 Argentine Society for Reproductive Medicine Marcos Horton 2010-2019 Colombian Association of Fertility and Jose Ignacio Madero 2004-2013 Reproductive Medicine Fertility Society of Australia Ossie Petrucco 2004-2013 German Society of Reproductive Medicine Tina Buchholz 2004-2013 Indian Society of Assisted Reproduction Dhiraj Gada 2010-2019 Japan Society of Reproductive Medicine Minoru Irahara 2007-2016 Jordanian Society for Fertility and Genetics Mazen El-Zibdeh 2010-2019 Swedish Society of Obstetrics and Gynecology Pietro Gambadauro 2007-2016 ASRM OFFICERS AND BOARD OF DIRECTORS 2012 - 2013
  8. 8. IFFS/ASRM Annual Meeting Policies and Disclaimers CANCELLATION POLICY The International Federation of Fertility Societies and the American Society for Reproductive Medicine reserve the right to cancel this activity due to unforeseen circumstances. In the event of such cancellation, the full enrollment fee will be returned to the registrant. REFUND/NON-ATTENDANCE POLICY Cancellations received before or by September 12th will receive a full refund minus a $50 processing fee. Cancellations received after September 12th will not be eligible for a refund. ADA STATEMENT The International Federation of Fertility Societies and the American Society for Reproductive Medicine fully comply with the legal requirements of the ADA and the rules and regulations thereof. Accommodations for Disabilities: Please notify the American Society for Reproductive Medicine, 1209 Montgomery Highway, Birmingham, Alabama, USA 35216, telephone 1-205-978-5000, a minimum of 10 working days in advance of the event if a reasonable accommodation for a disability is needed. EQUAL OPPORTUNITY STATEMENT The International Federation of Fertility Societies and the American Society for Reproductive Medicine value and promote diversity among its members, officers and staff. The Societies prohibit discrimination toward any member or employee due to race, color, religion, age, gender, sexual orientation, national origin, citizenship, disability, military status or other basis prohibited by law. IFFS and ASRM strive to achieve gender, racial and ethnic balance in hiring and governance. IFFS and ASRM maintain policies, procedures and personnel actions that conform to the letter and spirit of all laws and regulations pertaining to equal opportunity and nondiscrimination in employment, appointments and elections to office. DISCLAIMER STATEMENT The content and views presented in this educational activity are those of the faculty/authors and do not necessarily reflect those of the International Federation of Fertility Societies and the American Society for Reproductive Medicine. This material is prepared based upon a review of multiple sources of information, but it is not exhaustive of the subject matter. Therefore, healthcare professionals and other individuals should review and consider other publications and materials on the subject matter before relying solely upon the information contained within this educational activity to make clinical decisions about individual patients. 8
  9. 9. 9 Registration & Meeting Information 8 Register online @ www.asrm.org and receive immediate confirmation! ! On-site in Boston, MA Choices may be limited on-site. Pre-registration is recommended. On-Site Registration Desk: Boston Convention and Exposition Center How to Register Be Sure to Visit the Exhibit Hall For the safety of your child and in order to maintain the scientific nature of the display, no children under the age of 16 (except infants under 6 months of age carried in arms at all times) will be allowed in the Exhibit Hall. Strollers and infants in backpacks are not permitted in the Exhibit Hall or Poster Hall at anytime. Friday, October 11 . . . . . . . . . . . 2:00 p.m. – 7:00 p.m. Saturday, October 12 . . . . . . . . . 7:00 a.m. – 7:00 p.m. Sunday, October 13 . . . . . . . . . . 7:00 a.m. – 7:00 p.m. Monday, October 14 . . . . . . . . . . 7:00 a.m. – 5:00 p.m. Tuesday, October 15 . . . . . . . . . 7:00 a.m. – 5:00 p.m. Wednesday, October 16 . . . . . . . . 7:00 a.m. – 5:00 p.m. Thursday, October 17 . . . . . . . . . 7:00 a.m. – 1:00 p.m. Sunday, October 13 . . . . . . . . . 7:30 p.m.- 9:30 p.m. Monday, October 14 . . . . . . . . . 9:00 a.m.- 5:00 p.m. Tuesday, October 15 . . . . . . . . . 9:00 a.m.- 5:00 p.m. Wednesday, October 16 . . . . . . 9:00 a.m.- 5:00 p.m. Thursday, October 17 . . . . . . . . . . . . . . 9:00 a.m.- 12:00 p.m.
  10. 10. 10 Individual Registration for the 2013 IFFS/ASRM Annual Meeting opens April 30, 2012. Group Registration for the 2013 IFFS/ASRM Annual Meeting opens April 30, 2012. To register, visit: www.asrm.org and click on “Annual Meeting” and then “Register for 2013 Annual Meeting.” Use your 2013 IFFS/ASRM First Program as a guide in registering for the courses you wish to attend. For questions, please call (866) 471-7224 or (703) 449-6418 or email asrmregistration@jspargo.com. Register early to take advantage of discounted rates! Early Bird Deadline 7/12/2013 • Advanced Deadline 9/14/2013 Registration Information Book in the IFFS/ASRM Housing Block and save $50 off Registration fees! Cancellations received before or by September 12, 2013 will receive a full refund minus a $50 processing fee. Cancellations received after September 12, 2013 will not be eligible for a refund. CERTIFICATE OF ATTENDANCE Proof of attendance is available on request from J. Spargo at the registration desk. Continuing Education Credit information is located in the front of the Postgraduate Course syllabi, and the Final Program and online. ADMISSION BADGES Name badges will be issued for the Postgraduate and Scientific Programs and are required for admission. Spouse/guest badges will be issued and are required for admission to spouse/guest activities and the Exhibit Hall. PHOTO/AUDIO/VIDEO RECORDING Photographing or audio/video recording of any session for personal or commercial purposes without permission is prohibited.
  11. 11. 11 Registration Information POSTGRADUATE COURSE REGISTRATION FEES Early Bird Advanced Onsite By By After 7/11/2013 9/12/2013 9/12/2013 ASRM Member (Doctoral) One 1-day course $320 $350 $380 Two 1-day courses $580 $640 $700 One 2-day course $540 $600 $660 ASRM Member (Non-Doctoral) One 1-day course $220 $240 $260 Two 1-day courses $400 $440 $480 One 2-day course $380 $420 $460 Non-ASRM Member (Doctoral) One 1-day course $380 $420 $460 Two 1-day courses $680 $750 $820 One 2-day course $650 $720 $790 Non- ASRM Member (Non-Doctoral) One 1-day course $270 $300 $330 Two 1-day courses $480 $530 $580 One 2-day course $450 $500 $550 Medical Resident-In-Training, Fellow, Team Member from your office/practice One 1-day course $220 $240 $260 Two 1-day courses $400 $440 $480 One 2-day course $380 $420 $460 SRS Hands-on Postgraduate Courses $300 additional charge will apply SCIENTIFIC PROGRAM REGISTRATION FEES Early Bird Advanced Onsite By By After 7/11/2013 9/12/2013 9/12/2013 ASRM Member $595 $695 $795 (Doctoral) ASRM Member $495 $545 $595 (Non-Doctoral) ASRM Life Member $495 $545 $595 Fellow $495 $545 $595 (proof of status letter from chair/dept. head required) Non- ASRM Member $795 $895 $995 (Doctoral) Non- ASRM Member $495 $545 $595 (Non-Doctoral) Team Member from $495 $545 $595 your Office/Practice Medical $250 $250 $250 Resident-In-Training Full-time Student $250 $250 $250 (Full-time medical students and full-time graduate students working toward first doctorate; Documentation required) Developing Countries** $545 $620 $695 Spouse/Guest Program $100 $100 $100 (Spouse/Guest registration includes Opening Reception, Exhibit Hall, Plenary Sessions & Hospitality) TICKETED EVENTS Roundtable Luncheons $50/day You may attend only one Roundtable Luncheon per day. Women’s $30 Council Breakfast Wednesday, October 16, 2013 at 7:30 a.m. Museum Night $125 Wednesday, October 16, 2013 at 7:00 p.m. **Individuals from the following countries will receive a discounted rate on registration: Afghanistan, Bangladesh, Benin, Burkina Faso, Burundi, Cambodia, Central African Republic, Chad, Comoros, Democratic Republic of the Congo, Eritrea, Ethiopia, Gambia, Guinea, Guinea-Bissau, Haiti, Kenya, Democratic Republic of Korea, Kyrgyz Republic, Liberia, Madagascar, Malawi, Mali, Mozambique, Myanmar, Nepal, Niger, Rwanda, Sierra Leone, Somalia, Tajikistan, Tanzania, Togo, Uganda and Zimbabwe Morning Poster Sessions Poster Sessions will be held on Tuesday, Wednesday, and Thursday mornings from 7:00 a.m. until 9:00 a.m. Complimentary continental breakfast will be available. No reservation is required.
  12. 12. 12 Housing Information Book in the IFFS/ASRM Housing Block and SAVE $50 off Registration fees! To book housing for the 2013 IFFS/ASRM Annual Meeting, visit www.asrm.org Click on “Annual Meeting” and then the appropriate housing link. For questions, please call (866) 471-7224 or (703) 449-6418 or email asrmhousing@jspargo.com 1. Boston Park Plaza $285.00 Single (1 person/1 bed) $285.00 Double (2 people/1 bed) $285.00 Double/Double (2 people/2 beds) $305.00 Triple (3 people/2 beds) $325.00 Quad (4 people/2 beds) 2. Boston Marriott Copley Place $289.00 Single (1 person/1 bed) $289.00 Double (2 people/1 bed) $289.00 Double/Double (2 people/2 beds) $309.00 Triple (3 people/2 beds) $329.00 Quad (4 people/2 beds) 3. Courtyard Boston Downtown/Tremont $219.00 Single (1 person/1 bed) $219.00 Double (2 people/1 bed) $239.00 Double/Double (2 people/2 beds) $259.00 Triple (3 people/2 beds) $279.00 Quad (4 people/2 beds) 4. Fairmont Copley Plaza $297.00 Single (1 person/1 bed) $297.00 Double (2 people/1 bed) $297.00 Double/Double (2 people/2 beds) $327.00 Triple (3 people/2 beds) $357.00 Quad (4 people/2 beds) 5. Hilton Boston Financial District $275.00 Single (1 person/1 bed) $275.00 Double (2 people/1 bed) $275.00 Double/Double (2 people/2 beds) $295.00 Triple (3 people/2 beds) $315.00 Quad (4 people/2 beds) 6. Hyatt Regency Boston $275.00 Single (1 person/1 bed) $275.00 Double (2 people/1 bed) $275.00 Double/Double (2 people/2 beds) $300.00 Triple (3 people/2 beds) $325.00 Quad (4 people/2 beds) 7. Omni Parker House Hotel $249.00 Single (1 person/1 bed) $249.00 Double (2 people/1 bed) $249.00 Double/Double (2 people/2 beds) $279.00 Triple (3 people/2 beds) $309.00 Quad (4 people/2 beds) 8. Renaissance Boston Waterfront $309.00 Single (1 person/1 bed) $309.00 Double (2 people/1 bed) $309.00 Double/Double (2 people/2 beds) $329.00 Triple (3 people/2 beds) $349.00 Quad (4 people/2 beds) 9. Seaport Hotel $299.00 Single (1 person/1 bed) $299.00 Double (2 people/1 bed) $299.00 Double/Double (2 people/2 beds) $324.00 Triple (3 people/2 beds) $349.00 Quad (4 people/2 beds) 10. Sheraton Boston $299.00 Single (1 person/1 bed) $299.00 Double (2 people/1 bed) $299.00 Double/Double (2 people/2 beds) $319.00 Triple (3 people/2 beds) $339.00 Quad (4 people/2 beds) 11. Westin Boston Waterfront (Headquarters Hotel) $319.00 Single (1 person/1 bed) $319.00 Double (2 people/1 bed) $319.00 Double/Double (2 people/2 beds) $339.00 Triple (3 people/2 beds) $359.00 Quad (4 people/2 beds) 12. Westin Copley Plaza $319.00 Single (1 person/1 bed) $319.00 Double (2 people/1 bed) $319.00 Double/Double (2 people/2 beds) $339.00 Triple (3 people/2 beds) $359.00 Quad (4 people/2 beds)
  13. 13. 13 Boston Hotel Map2013IFFS/ASRMCONJOINTMEETING
  14. 14. 14 Disclosure Statements/Conflict of Interest Policy 2013 IFFS/ASRM Conflict of Interest Policy for Invited SpeakersHonoraria The following speakers may receive honoraria and/or discounted or free registration: • Plenary Speakers • Postgraduate Course Faculty • Trilogy Speakers • Symposia Speakers • Interactive Session Speakers The following speakers do not receive honoraria: • Roundtable Presenters • Abstract Presenters • Video Presenters Disclosure Statements Postgraduate Faculty, Symposia Speakers, Plenary Lecturers, Abstract Authors, Abstract Graders, Round- table Presenters, Video Presenters, and Interactive Speakers are required to disclose commercial relationships or other activities that might be perceived as potential conflicts of interest. Postgraduate course faculty disclosures will be listed in the course syllabi. Symposium speakers’ disclosures will be presented in handout materials, as well as on slides. Disclosures from speakers in the Plenary Sessions, Interactive Sessions, Roundtables, Videos and Symposia will be published in the Final Program. Abstract authors’ disclosures will be published in the 2013 Program Supplement. Each presenter should reveal his/her disclosure information during his/her presentation, preferably with the visual aid of a slide. Roundtable presenters should provide a copy of their disclosure forms to the participants at their table. As a provider of continuing medical education (CME) accredited by the Accreditation Council for Continuing Medical Education (ACCME), the American Society for Reproductive Medicine must ensure balance, independence, objectivity and scientific rigor in all its educational activities. All presenters must disclose to the learners any commercial or financial interests and/or other relationships with manufacturers of pharmaceuticals, laboratory supplies and/or medical devices. All relationships, whether or not they directly apply to this CME event, must be disclosed. All non-FDA approved uses of products must be clearly identified. Disclosures may be made in the form of a slide, printed material, or oral statement. The intent of this disclosure is not to prevent a speaker with a commercial or financial interest from making a presentation. The intent is to assist ASRM in resolving conflicts of interest and to provide learners with information on which they can make their own judgments regarding any bias. Although ASRM reviews and resolves potential conflicts of interest, it remains for the audience to determine whether the speaker’s interests or relationships may influence the presentation with regard to exposition or conclusion. Disclosures will be revealed to the learners. For postgraduate courses, disclosure information will be provided in the syllabus. For other activities, where no syllabus or other similar printed material is available, disclosures must be made verbally to the audience by the speakers, preferably with the visual aid of a slide. For those situations where there is no potential for conflict of interest, the portion of the form that so states should be completed. In those situations where a speaker does not complete a form or refuses to complete a form, the individual is ineligible to participate as a speaker in the CME activity. Speakers should also reveal to the audience any “off label” uses (not approved by the FDA) of any drugs or products discussed. Abstract authors’ disclosures are listed in the 2013 Program Supplement. Speakers in the Symposia and Interactive, Video, Roundtable and Abstract Sessions have also complied with ASRM policies and their disclosures are printed in the ASRM Final Program. The speaker should reveal this information during his/her presentation, preferably with the visual aid of a slide. Continuing Medical Education and Continuing Education Credits will be available.
  15. 15. 15 46TH ANNUAL POSTGRADUATE PROGRAM COMMITTEE CHAIR Anuja Dokras, M.D., Ph.D. CO-CHAIR Lisa M. Halvorson, M.D., Ph.D. COORDINATING CHAIR Bradley J. Van Voorhis, M.D. WEEKEND COURSES Dates: Saturday, October 12TH Sunday, October 13ST Hours: 8:15 a.m.-5:00 p.m. Lunch is from Noon-1:00 p.m. Courses PG1-PG12 are one-day courses on Saturday. Courses PG13-PG26 are one-day courses on Sunday. Course PG27 is a two-day course on Saturday and Sunday. Postgraduate Course Syllabi will be posted online in September 2013. Printed copies will be distributed on-site. Postgraduate Program One-Day Courses Saturday, October 12, 2013 GLOBAL APPROACHES TO PREVENTING INFECTIONS IN THE ART LABORATORY: FROM THEORY TO PRACTICE Course PG1 (Saturday) Developed in Cooperation with the International Federation of Fertility Societies FACULTY Deborah J. Anderson, Ph.D., Chair NEEDS ASSESSMENT AND COURSE DESCRIPTION Different regions of the world have different infections in the population that impact the practice of assisted reproductive technologies. The challenge for laboratory and clinical staff of ART clinics is to prevent transmission of infectious agents to the mother or gestational carrier and to the offspring of ART procedures. The objective of this live course is to train all members of the professional ART team to implement clinical and laboratory procedures to reduce the risk of transmission of infectious agents. ACGME Competency Patient care LEARNING OBJECTIVES At the conclusion of this course, participants should be able to: 1. Summarize the prevalence and characteristics of concern in different populations around the world. 2. Design and implement practices to prevent infection in ART clinics in developed countries. 3. Discuss implementation of procedures to prevent infection in ART clinics in developing countries. CODING FOR REPRODUCTIVE MEDICINE PRACTICES 2013 Course PG2 (Saturday) Developed in Cooperation with the American Society for Reproductive Medicine Coding Committee FACULTY John T. Queenan Jr., M.D., Chair NEEDS ASSESSMENT AND COURSE DESCRIPTION Every reproductive medicine practice has a legal and ethical obligation to follow a specific set of rules and regulations that determine how reimbursements are calculated. Failure to follow these rules can result in unfair practices to patients and/or legal consequences from government or third-party payers. The problem is those rules and regulations have become so complex that most people cannot understand them without receiving special training. This live course, designed for physicians, practice managers, billers, office managers, sonographers, laboratory managers, and physician assistants, will include didactic lectures, panel discussions, case presentations and interactive question and answer sessions. The correct way to report diagnostic codes and select the appropriate procedure codes will be explained, with a focus on quality improvement and minimizing errors. Systems- based resources available to aid in improving patient billing accuracy will be addressed, as will information technology resources that provide participants with the ability to continue updating their knowledge of correct coding in the future. Special attention will be given to the upcoming changes in the International Statistical Classification of Diseases and Related Health Problems (ICD), 10th Revision. ACGME Competency Systems-based practice LEARNING OBJECTIVES At the conclusion of this course, participants should be able to:
  16. 16. 16 46TH ANNUAL POSTGRADUATE PROGRAM COMPLICATIONS OF ART: IN SEARCH OF A HAPPY ENDING Course PG3 (Saturday) Developed in Cooperation with the Nurses’ Professional Group FACULTY Angela Smith, N.P., Chair Tamara M. Tobias, A.R.N.P., Co-Chair NEEDS ASSESSMENT AND COURSE DESCRIPTION The successful outcome of fertility treatment brings joy to many couples. Unfortunately, some treatments result in complications that present complex issues and require special management strategies. These may include ovarian hyperstimulation syndrome (OHSS), ectopic pregnancy, pregnancy loss, multiple pregnancy and treatment failure. The decision to use third-party reproduction may be difficult and other psychological complications such as depression, isolation and relationship strain may add additional obstacles. Healthcare providers must understand the problems that may occur, discuss treatment and management strategies, and recognize when referrals or other resources are needed. The factors that may prevent or reduce the risk of ovarian hyperstimulation syndrome and management strategies for ectopic and multifetal pregnancy will be addressed in this course. The psychological complications of pregnancy loss and treatment failure will be examined. In addition, the psychosocial issues of third-party reproduction, depression, isolation and relationship stressors will be explored. The goal of this live course is to increase the ability of nursing professionals to avoid potential complications of fertility treatment and to provide patients with strategies to navigate their fertility journeys.       ACGME Competency Practice-based learning and improvement LEARNING OBJECTIVES At the conclusion of this course, participants should be able to: 1. Discuss OHSS and various strategies to prevent this syndrome and the effectiveness of those strategies. 2. Review the management and impact of an ectopic pregnancy. 3. Explore the emotional influence of treatment failure and pregnancy loss. 4. Explain the unique issues confronting multifetal pregnancies and current treatment strategies. 5. Examine the psychological implications of third-party reproduction, depression, isolation and relationship stressors which may ensue from fertility treatment. 1. Demonstrate correct coding of diagnostic conditions that are typically encountered in the practice of reproductive endocrinology. 2. Identify the correct Current Procedural Terminology (CPT) code for surgical procedures encountered in the practice of reproductive endocrinology and list additional resources available to aid with correct coding procedures in the future. 3. Summarize the rules and regulations required by third-party payers regarding documentation guidelines to verify that physician services were rendered according to medical necessity and in accordance with the requirements of CPT. 4. Describe the proper steps for successful verification or negotiation of coverage in obtaining third-party payer coverage for fertility services.
  17. 17. 17 46TH ANNUAL POSTGRADUATE PROGRAM Developed in Cooperation with the Society of Reproductive Biologists and Technologists FACULTY Marybeth Gerrity, Ph.D., M.B.A., Chair NEEDS ASSESSMENT AND COURSE DESCRIPTION Cryopreservation of reproductive cells and tissues has been practiced for more than half a century. However, lack of consensus on best practices has led to variable cryopreservation success rates that may hamper clinical utilization. While human sperm has been cryopreserved for decades, techniques such as oocyte vitrification are relatively recent technology breakthroughs. The learning curve for some of these techniques can be steep and best practices for how to determine a laboratory’s competence to perform the procedures are still evolving. As the types of patients who are candidates for cryopreservation procedures expand beyond fertility patients to include those with chronic diseases, it may not be feasible to mount multiple attempts at cryopreservation. Optimizing outcomes from the outset will be critical. Review of the Society forAssisted Reproductive Technology (SART) outcome statistics indicate the outcomes with cryopreservation of embryos vary by center, and strategies for assessing the cause of the variability must be developed before the technique is offered to patients who may have only one chance for a successful outcome (e.g., cancer patients). At the same time, long-term storage of these frozen cells and tissues presents challenges to long-term success. Cells formerly stored for several years may now be stored for decades. As frozen egg banks become more common, the lessons learned from years of sperm banking should not be lost and good tissue-banking practices must be implemented. Finally, experimental techniques that broaden the types of tissues that can be cryopreserved are in use at some centers. Knowledge of these methods, including their strengths, weaknesses and limitations, is essential in determining if they are safe and efficacious and ready to move into widespread use or should be reserved for specialized centers. This live course for laboratory clinicians will cover current cryopreservation techniques and their application outside of infertility treatment, instituting competency-based training in laboratories, and issues of long-term storage of cells and tissues. ACGME Competency Patient care LEARNING OBJECTIVES At the conclusion of this course, participants should be able to: 1. Describe the scope of the clinical use of cryopreservation of reproductive tissues and cells outside of infertility treatment. 2. Assess the best methods for cryopreservation according to tissue type, including factors that can limit success. 3. Design a plan for competency-based training that can be instituted for each cell or tissue type. 4. Discuss the unique technical, financial, logistical and regulatory challenges of long-term storage of reproductive cells and tissues. 5. Compare and contrast the practice of long-term banking of anonymous sperm donors with that of egg donors and answer the question, “What can egg banks learn from sperm banks?” CRYOPRESERVATION OF REPRODUCTIVE CELLS AND TISSUES: REAL WORLD APPROACHES AND LABORATORY PEARLS Course PG4 (Saturday) A SIMPLIFIED RISK-FREE IVF WITHOUT COMPROMISING OUTCOME Course PG5 (Saturday) Developed in Cooperation with the Middle East Fertility Society FACULTY Mohamed Aboulghar, M.D., Chair NEEDS ASSESSMENT AND COURSE DESCRIPTION The success of in vitro fertilization (IVF) is affected by patients’ reproductive status, the stimulation protocol and the quality of gametes and embryos. These parameters can vary greatly among IVF clinics. It is necessary to optimize the clinical and laboratory procedures to ensure the highest quality embryos. This live course for physicians, nurses and laboratory staff of IVF clinics is designed to highlight the latest medical evidence in assisted reproductive technology. The course will describe how to simplify the IVF procedure beginning with stimulation protocols. The faculty will address minimal monitoring, newer options for triggering ovulation, assuring safety of IVF by prevention of ovarian hyperstimulation syndrome (OHSS) and multiple pregnancy, and simplifying the laboratory and freezing procedures without reducing the pregnancy rate. ACGME Competency Patient care LEARNING OBJECTIVES At the conclusion of this course, participants should be able to: 1. Perform natural- and clomiphene-cycle IVF. 2. Describe the soft protocols for ovarian stimulation in IVF. 3. Explore newer options for triggering ovulation with minimum risk. 4. Avoid OHSS in performing IVF. 5. Discuss the benefits and risks of single-embryo transfer and cryopreservation.
  18. 18. 18 46TH ANNUAL POSTGRADUATE PROGRAM BRIDGING THE GAP BETWEEN SCIENCE AND CLINICAL CARE IN ENDOMETRIOSIS-RELATED INFERTILITY Course PG6 (Saturday) Developed in Cooperation with the Endometriosis Special Interest Group FACULTY Hugh S. Taylor, M.D., Chair NEEDS ASSESSMENT AND COURSE DESCRIPTION Endometriosis is a highly prevalent disease. However, there are many gaps in physicians’ competence to diagnose patients with endometriosis. This disease places a tremendous burden on society, both economically and related to quality of life. The principal manifestations of this disease, which causes both infertility and chronic pain, mandate that all general gynecologists and subspecialists be involved in the care of these patients. This live course is designed to improve physicians’ competence in the medical and surgical management of endometriosis. Topics to be discussed include: pathophysiology of endometriosis-associated pain syndromes; pathophysiology of endometriosis-associated infertility; choosing an appropriate medical or surgical therapy; technical aspects of surgical approaches; in vitro fertilization (IVF) approaches, including pre-IVF optimization; and new genetic etiologies of endometriosis. Coherent summaries with key learning points will be provided and reinforced during the session of case reports. ACGME Competency Patient care LEARNING OBJECTIVES At the conclusion of this course, participants should be able to: 1. Discuss clinical implications of the pathophysiology of endometriosis in patients with infertility. 2. Explain the new genetic etiologies for endometriosis and ways to identify those at risk. 3. Describe the options for managing endometriosis before an IVF cycle. 4. Summarize the optimal approach for an IVF cycle in a woman with endometriosis. Developed in Cooperation with the American Institute of Ultrasound in Medicine and the Imaging in Reproductive Medicine Special Interest Group FACULTY Laurel A. Stadtmauer, M.D., Ph.D., Chair Todd Deutch, M.D., Co-Chair NEEDS ASSESSMENT AND COURSE DESCRIPTION Ultrasound has become the most widely used and important tool in diagnosis and treatment of infertility. Ultrasound and ultrasound- guided procedures have become integral components not just of assisted reproductive technology (ART), but also in the day-to-day practice of reproductive medicine, infertility and gynecology. 3-D ultrasound allows better imaging, as well as more accurate volume rendering. It has become the gold standard for the diagnosis of uterine anomalies, and may assist in more accurate follicular monitoring measurements. In 2009, new practice guidelines for ultrasound in reproductive medicine were published by the American Institute of Ultrasound in Medicine (AIUM) and in collaboration with the American Society for Reproductive Medicine (ASRM). Surveys of members of the Society for Reproductive Endocrinology and Infertility, the Imaging Special Interest Group and ASRM have revealed a strong desire for CME credits in ultrasonography that would prepare reproductive medicine professionals and gynecologists for accreditation by AIUM. In addition, there is an interest in training and credentialing reproductive nurses and nurse practitioners to perform limited ultrasounds in the office. This live one-day course, designed to meet the needs of physicians and other healthcare providers who use gynecologic sonography, will fulfill CME requirements for AIUM credentialing. The objective of this course is to provide a comprehensive survey of the use of ultrasonography in the female pelvis for physicians, nurses and ultrasonographers actively involved in reproductive medicine, infertility and gynecology. This course will emphasize the use of ultrasound in maximizing ART success and including follicular monitoring with 3-D sonographic automatic volume calculation, assessment of the uterine lining during retrieval and embryo transfer in an evidence-based manner. Newer technologies, such as 3-D ultrasound, Doppler and the use of CT- and MRI-guided procedures, will also be discussed, along with cost- effective current or potential applications. Participants will be encouraged to actively take part in case presentations and discussions of controversies. Practical applications of the technology will be addressed along with case presentations, and participants will have the opportunity to manipulate 3-D images. ULTRASOUND IMAGING IN ART Course PG7 (Saturday)
  19. 19. 19 ACGME Competency Patient care LEARNING OBJECTIVES At the conclusion of this course, participants should be able to: 1. Summarize the appropriate use of ultrasonography in the evaluation of infertility, uterine abnormalities and the pathology of the reproductive tract. 2. Describe the proper assessment of early pregnancy and list findings on early pregnancy assessments that are associated with poor outcome. 3. Discuss the importance of 3-D ultrasonography in reproductive medicine, and the importance of Doppler blood-flow assessment in reproductive medicine and gynecology. 4. Evaluate the use of fallopian tube patency with ultrasound. 5. Critically evaluate how ultrasound can maximize the success of ART. CRITERIA FOR WORLD-CLASS PERFORMANCE EXCELLENCE Course PG8 (Saturday) 46TH ANNUAL POSTGRADUATE PROGRAM Developed in Cooperation with the Association of Reproductive Managers FACULTY Joseph J. Travia, Jr., B.S., M.B.A., Chair NEEDS ASSESSMENT AND COURSE DESCRIPTION Reproductive medicine facilities are confronted with more challenges than ever before from patients expecting world-class service and results. With slower annual growth and a competing global economy, being good is no longer an option; patients want the best. Patients are well informed through social media and other Internet resources, and their expectations for good outcomes continue to rise. Their initial selection of a clinic will be based on cutting-edge technology and published results. If patients remain with their initial selection, that decision will be based on the level of service they received during their first visit. Scientific breakthroughs continue to provide new opportunities for meeting the needs of assisted reproductive technology (ART) patients world-wide. This live course is designed for practitioners wanting to create a world-class experience for their patients through performance excellence at every level of their organization. From creative leadership, strategic planning, patient focus, measurement, analysis and knowledge management to work environment and employee engagement, this course will enable every participant to contribute significantly to their practice's reach for excellence. ACGME Competency Systems-based practice LEARNING OBJECTIVES At the conclusion of this course, participants should be able to: 1. Formulate the critical logistics of strategic planning and implementation, with a focus on patient recruitment and retention. 2. Convert strategic objectives into action plans, along with key action plan indicators to measure competency and performance results in the practice. 3. Provide a world-class work environment that promotes creative leadership and employee engagement. 4. Determine the best, most competitive healthcare service offerings for the practice, and the most effective patient and stakeholder communication vehicles to market those opportunities. 5. Measure, analyze, review and improve performance at all levels of the organization through the information already available in clinical, laboratory, and operations databases.
  20. 20. 20 THE ART OF GENETICS: REPRODUCTIVE GENETICS IN THE ART SETTING Course PG9 (Saturday) 46TH ANNUAL POSTGRADUATE PROGRAM Developed in Cooperation with the Genetic Counseling Special Interest Group FACULTY Jill M. Fischer, M.S., C.G.C., Chair NEEDS ASSESSMENT AND COURSE DESCRIPTION Reproductive genetics is an increasing part of the assisted reproductive technology (ART) practice. Daily, ART centers use genetic information when couples undergo ethnicity screening, when donors are screened and chosen for recipient couples, to determine the cause of infertility or recurrent pregnancy loss, and when utilizing preimplantation genetic screening (PGS) and preimplantation genetic diagnosis (PGD). However, the application of genetic information and genetic testing is often limited due to lack of knowledge by the medical providers in the ART practice. Education of these medical providers is incomplete and most ART centers do not have a genetic counselor on staff. This live course serves to provide basic to complex genetic information to help such practices start to fill this education gap and competently apply genetic information to improve patient care. The course will provide both basic genetics education and review of real time application. The faculty will address current knowledge of the genetic causes of male infertility not limited to cystic fibrosis and genetic causes of female infertility, including the latest research on and testing for fragile X syndrome. As high throughput carrier testing options become more readily available, current American Society for Reproductive Medicine (ASRM), American College of Obstetricians and Gynecologists (ACOG) and American College of Medical Genetics (ACMG) carrier testing guidelines will be outlined and the application of such testing discussed. Current PGS/PGD test techniques and applications will be examined. Overall, this course should educate the ART medical professionals on current genetic information and test options so they can improve patient care in their practices. ACGME Competency Patient care LEARNING OBJECTIVES At the conclusion of this course, participants should be able to: 1. Explain genetic inheritance patterns, risk assessment and ethnicity screening. 2. Describe genetic and chromosomal causes of male and female infertility and infertility test options. 3. Define genetic and chromosomal test options for recurrent pregnancy-loss patients. 4. Outline donor carrier screening guidelines by ASRM, ACOG and ACMG and their application to current practice. 5. Evaluate the value of high throughput carrier screening in the ART setting and review current test techniques and applications of PGD. Developed in Cooperation with the Mental Health Professional Group FACULTY Andrea Mechanick Braverman, Ph.D., Chair NEEDS ASSESSMENT AND COURSE DESCRIPTION The idea of Mommy and Daddy and baby makes three as depicted in the 1950s “Leave it to Beaver” representation of the family has been put into rerun by the new American family of “Modern Family” and “Two and a Half Men.” Many of the new families are made possible only by assisted reproductive technology (ART). Single mothers by choice and single fathers by choice are emerging as “choice” families. Co-in vitro fertilization (IVF) with lesbian partners sharing the genetic and gestational contribution to their children is now a common procedure. On the horizon are families where Mom freezes her eggs in her 20s or 30s but is now ready to fertilize an egg and get pregnant in her 40s and 50s. This live course will increase mental health professionals’ understanding of the many new ART families. This course will provide participants with the current research and theories explaining the needs and challenges for these families. Utilizing an interactive format of a mock trial, participants will have the opportunity to hear “testimony” and be “the jury” to identify the issues and concerns of these ART families. This course will equip mental health professionals in providing competent understanding and sensitivity to the ever-expanding All-American family. ACGME Competency Interpersonal and communication skills LEARNING OBJECTIVES At the conclusion of this course, participants should be able to: 1. Describe the different types of families made possible by ART. 2. Discuss the current literature on the new ART families. 3. Explain the challenges to providers in counseling these new ART families. NEW FAMILIES ON TRIAL Course PG10 (Saturday)
  21. 21. 21 46TH ANNUAL POSTGRADUATE PROGRAM Developed in Cooperation with the Society for Assisted Reproductive Technology FACULTY James M. Goldfarb, M.D., Chair NEEDS ASSESSMENT AND COURSE DESCRIPTION Third-party reproduction, particularly oocyte donation (OD) and gestational surrogacy (GS), has received much professional and public attention recently. Both of these procedures have been utilized since the mid-1980s, but as they have evolved, the medical, legal and psychological/ethical complexities have all increased. It is imperative that individuals involved with these procedures be aware of all the complex issues involved. Embryo donation (ED) and sperm donor insemination (DI) have attracted less attention and are medically not as complex as OD and GS. However, they, too, are associated with significant legal and psychological/ethical issues. This live course, designed for medical professionals involved in assisted reproductive technology (ART), examines the medical, legal and psychological/ethical issues involved in OD and GS, and to a lesser extent, ED and DI. Medical topics to be discussed include: safety considerations and inclusion/exclusion criteria for egg and sperm donors and gestational surrogates, number of embryos to transfer in egg and embryo donor and gestational surrogate cycles, and role of oocyte cryopreservation in OD cycles. Legal topics will include: model legislation by the American Bar Association, variation in regulation of third-party reproduction in different states, new legislative proposals to regulate third-party reproduction, informed consent and legal pitfalls. Psychological/ethical issues will include: egg donor and gestational surrogate payment, participant coercion, shared egg donation, divulging to offspring, and psychological aspects and screening tools of third-party reproduction. ACGME Competency Patient care LEARNING OBJECTIVES At the conclusion of this course, participants should be able to: 1. Explain the legal issues regarding OD, GS, ED and DI, particularly regarding state legislative efforts to regulate third-party reproduction. 2. Discuss issues with egg donation, including establishment of a national egg donor registry, differences between anonymous and directed egg donation, and guidelines for payment of egg donors. 3. Summarize the status of cross-border reproductive care as it relates to OD and GS. ENDOMETRIUM AND EMBRYO CROSS-TALK: HOW TO PREDICT AND ACHIEVE IMPLANTATION SUCCESS Course PG12 (Saturday) Developed in Cooperation with the European Society of Human Reproduction and Embryology FACULTY Antonis Makrigiannakis, M.D., Ph.D., Chair NEEDS ASSESSMENT AND COURSE DESCRIPTION During implantation, the cross-talk between the embryo and the endometrium remains largely unknown. Local and systemic players interact for the achievement of human pregnancy. Impaired implantation is currently considered the most important limiting factor for the establishment of viable pregnancies in assisted reproduction. It is expected that elucidating the molecular background of the process will enable accurate diagnosis and effective treatment of implantation failure and/or miscarriages. The purpose of this live course for embryologists and clinical reproductive medicine specialists is to identify factors that predict implantation success and investigate potential treatment modalities to manage implantation failure and/or miscarriages. ACGME Competency Medical knowledge LEARNING OBJECTIVES At the conclusion of this course, participants should be able to: 1. Summarize the physiology and pathophysiology of implantation. 2. Describe local and systemic factors leading to miscarriages and/or implantation failure. 3. Discuss the challenges of predicting and achieving implantation success. THIRD PARTY REPRODUCTION IN THE UNITED STATES: LEGAL, MEDICAL AND PSYCHOLOGICAL/ETHICAL ASPECTS Course PG11 (Saturday)
  22. 22. 22 PCOS: CARING FOR A WOMAN OVER HER LIFETIME Course PG13 (Sunday) 46TH ANNUAL POSTGRADUATE PROGRAM Developed in Cooperation with the Society for Reproductive Endocrinology and Infertility FACULTY Kurt T. Barnhart, M.D., M.S.C.E., Chair NEEDS ASSESSMENT AND COURSE DESCRIPTION Polycystic ovary syndrome (PCOS) is the most common endocrine disorder in females of reproductive age and is highly prevalent. The etiology of this heterogeneous condition remains obscure and its phenotype expression varies. PCOS affects many aspects of a woman’s life and this live course will supply the reproductive endocrinologist and general gynecologist with the latest information on PCOS in order to provide up-to-date recommendations for patient care. Topics to be covered will include how PCOS affects reproductive health over a woman’s lifespan, hirsutism and acne, contraception, fertility, menstrual cycle abnormalities, quality of life, ethnicity, pregnancy complications, long-term metabolic and cardiovascular health and, finally, cancer risk. Information will include material from The Consensus on Women’s Health Aspects of Polycystic Ovary Syndrome. ACGME Competency Practice-based learning and improvement LEARNING OBJECTIVES At the conclusion of this course, participants should be able to: 1. Contrast the signs and symptoms of PCOS in women of different ages and ethnicities. 2. Interpret how aspects of the phenotype of PCOS correlate with risk factors for insulin resistance, diabetes mellitus (DM) type II and cardiovascular health. 3. Develop a practical approach to testing for precursors of DM and cardiovascular disease in women with PCOS. 4. Distinguish the medical and reproductive needs of a women with PCOS based on where she is in her lifetime. One-Day Courses Sunday, October 13, 2013 CROSSING BORDERS AND OTHER HOT LEGAL ISSUES FOR THE HEALTHCARE PROVIDER AND LEGAL PRACTITIONER Course PG14 (Sunday) Developed in Cooperation with the Legal Professional Group FACULTY Nidhi Desai, J.D., Chair NEEDS ASSESSMENT AND COURSE DESCRIPTION The involvement of third parties in assisted reproduction as gamete and embryo donors and as gestational carriers has produced a plethora of legal issues for the reproductive healthcare professional. Confronted with the complicated relationships among intended parents, gamete donors and gestational surrogates, the medical team often does not appreciate the legal implications of treating patients from different countries. While medical practitioners should not offer legal advice, awareness of the legal complexities and possible landmines their patients may encounter with respect to immigration, contract enfoceability and parentage will help better serve practices and patients. Recognition of those arrangements that require a partnership of legal and medical experts is essential in the creation of legally-secure families. The medical practitioner often has a lack of understanding of legal issues related to developments in new technologies and the interaction of the laws of various jurisdictions when treating or advising international clients. This live course will provide guidance to the healthcare practitioner and lawyer advising patients who are traveling from other countries as well as those patients traveling out of the United States for treatment. Topics will include treatment, parentage, immigration, and contract enforceability given the intersection of multiple jurisdictions. The course will further explore current hot topics in assisted reproductive technology such as egg freezing and international regulations. This presentation is designed to review commonly-encountered situations that are subject to legal scrutiny, define the legal issues and potential pitfalls, provide practical solutions to roadblocks in assisted reproductive technology arrangements and explore the legal significance of treating clients from other countries. The various speakers will further address issues emerging as a result of newer technology based on legal precedent and principles. Each presenter will field questions from attendees that will allow for discussion of particular clinical conundrums, with the opportunity to develop usable solutions for clinical practice. This program will feature a practical approach to help lawyers and physicians better field situations as they arise. ACGME Competency Systems-based practice
  23. 23. 23 46TH ANNUAL POSTGRADUATE PROGRAM LEARNING OBJECTIVES At the conclusion of this course, participants should be able to: 1. Explain problematic issues arising out of cross-border care. 2. Construct specific steps for clinics to take to protect their programs and patients. 3. Discuss some of the emerging legal challenges brought on by newer assisted reproductive technologies. 4. Formulate practical methods of dealing with these emerging issues. LEIOMYOMATA: CLINICAL UPDATES, RESEARCH DEVELOPMENTS AND DISPARITIES IN DISEASE, OUTCOMES AND ACCESS TO CARE Course PG15 (Sunday) Developed in Cooperation with the Fibroid Special Interest Group and the Health Disparities Special Interest Group FACULTY Gloria Richard-Davis, M.D., Chair Ayman Al-Hendy, M.D., Ph.D., Co-Chair NEEDS ASSESSMENT AND COURSE DESCRIPTION Uterine leiomyomata (fibroids), benign estrogen-dependent tumors of the uterine wall, are a common cause of acute and chronic pelvic pain in women. Uterine fibroids affect 40-80% of women of reproductive age and are the leading indication for hysterectomy in African- American women. More than 600,000 hysterectomies were done in the United States in 2000 because of leiomyomata. At a mean cost of $8 billion per year, African-American women are particularly affected as the prevalence of uterine fibroids is about three times higher in that ethnic group compared with Caucasians. Currently there is no effective medical treatment for this common disease, and the impact of uterine fibroids on fertility remains controversial. Treatment options for the management of fibroids have largely focused on surgical options with few focusing on reproductive-sparing procedures. Healthcare providers show no agreement on the best management option, partially because of their lack of current evidence-based knowledge (including the cause), of uterine fibroids. This live course, designed for gynecologists, will provide a clear and meaningful overview of the problem, discuss current fibroid treatment options and their effect on fertility, and probe the future of these treatments. ACGME Competency Patient care LEARNING OBJECTIVES At the conclusion of this course, participants should be able to: 1. Explain the developmental origin of uterine fibroids. 2. Describe non-surgical, reproductive-sparing approach for treatment of uterine leiomyomata. 3. Summarize the scientific data on why uterine leiomyomata are more common in African Americans. 4. Discuss the role of myomectomy in the outcomes of assisted reproductive technologies. CRYOBIOLOGY, CRYOPHYSICS AND QUALITY CONTROL CONCERNS OF GAMETE, EMBRYO AND TISSUE VITRIFICATION Course PG16 (Sunday) Developed in Cooperation with the Society of Reproductive Biologists and Technologists FACULTY Charles L. Bormann, Ph.D., Chair Marybeth Gerrity, Ph.D., M.B.A., Co-Chair NEEDS ASSESSMENT AND COURSE DESCRIPTION The presentation of vitrification (VTF) to in vitro fertilization (IVF) laboratories and practices is often unscientific and chaotic. The majority of demonstration and training in VTF techniques has come through workshops sponsored by industry, which are inherently biased toward the media and storage vessels that the company presenting the training has developed. With increasing pressures to conform to human cells, tissue and tissue products (HCT/P) and current good tissue practice (CGTP) standards, set forth by the Food and Drug Administration (FDA), most laboratories are compelled to use devices that are FDA-approved or pending FDA approval. There is great concern surrounding the “technical signature” of using a published VTF method, questioning the simplicity, reliability and repeatability of a given technique. There are growing concerns over the safety of VTF solutions used, cryo-security, and accepting VTF eggs/embryos in unfamiliar VTF devices. We are entering a new era of cryobiology where we are faced with serious quality control challenges. Alternative approaches presented in this live demonstration and hands-on workshop can offer universal uniformity in safety, simplicity, sterility, security and success. To by-pass commercial propaganda and technical signature issues, a hands-on demonstration and workshop of three simple, practical devices currently in use will be used to emphasize the quality control nightmare we will be facing if alternative universal technique(s) are not adopted. Selection of these devices (0.25 mL straw, Hemi straw, and microSecure) for demonstration was based on proven simplicity, low cost, safety and effectiveness of each device without vested commercial interest. This course will provide a solid background in the theories and basic science that has led to the current state of VTF in human systems. We will evaluate the various VTF methods by rating the pros and cons after hands-on experience. We will demonstrate good tissue practices (GTPs) and discuss quality control concerns.
  24. 24. 24 46TH ANNUAL POSTGRADUATE PROGRAM ACGME Competency Patient care LEARNING OBJECTIVES At the conclusion of this course, participants should be able to: 1. Participate in the cryobiological/cryophysical principles behind VTF technology via a “hands-on” workshop and contrast VTF to standard slow-freeze preservation. 2. Evaluate, demonstrate and practice various non-commercial VTF methods that have been developed and applied, and assess the pros and cons in establishing a VTF program. 3. Demonstrate laboratory GTPs and quality control concerns of VTF, and show how they influence intra- and inter-laboratory success within the methods and devices used in the hands-on workshop. 4. Discuss overall quality management in striving to develop a standard global VTF technique (that minimizes “technical signature”) by participating in the use of various VTF techniques. MODERN MANAGEMENT OF POLYCYSTIC OVARY SYNDROME IN ADOLESCENTS Course PG17 (Sunday) Developed in Cooperation with the Pediatric and Adolescent Gynecology Special Interest Group FACULTY Jennifer E. Dietrich, M.S., M.Sc., Chair NEEDS ASSESSMENT AND COURSE DESCRIPTION Polycystic ovary syndrome (PCOS) affects an estimated 5-7% of women of reproductive age. True estimates are difficult to define in adolescents, but have been postulated to be higher. Because PCOS is associated with comorbidities such as diabetes mellitus type II, hypertension, non-alcoholic steatosis and obesity as well as other health problems, it is critical to establish an early diagnosis to avoid significant health problems later in life. This live course designed for clinicians who care for adolescent females will cover current scientific papers and new areas of research that focus on adolescent needs and screening. Through a lecture/audience participation format, participants will discuss early warning signs such as precocious adrenarche that help providers determine the best time to screen adolescents for PCOS, which should result in improved patient lifelong health. ACGME Competency Medical knowledge LEARNING OBJECTIVES At the conclusion of this course, participants should be able to: 1. Confidently perform an evaluation for PCOS on an adolescent female. 2. Differentiate adult criteria from adolescent criteria in making the diagnosis of PCOS. 3. Detect early warning signs indicating a possible diagnosis of PCOS in the adolescent and evaluate the need for early screening and early intervention. 4. Discuss the available treatment options for adolescents with PCOS. EARLY LIFE TOXICANT EXPOSURES AND ADULT REPRODUCTIVE DISORDERS: A POTENTIAL ROLE FOR NUTRITIONAL INTERVENTION IN BOTH SEXES Course PG18 (Sunday) Developed in Cooperation with the Environment and Reproduction Special Interest Group and the Nutrition Special Interest Group FACULTY Kevin G. Osteen, Ph.D., H.C.L.D., Chair NEEDS ASSESSMENT AND COURSE DESCRIPTION Fetal programming is a normal component of developmental processes leading to appropriate organ system function in adults. However, early life programming processes can be negatively impacted by various environmental factors, including maternal stress, poor nutrition and exposure to various toxicants. Emerging evidence implies that disruption of fetal and neonatal programming may significantly affect an individual’s risk of adult disease, including reproductive failure. This concept, known as Developmental Origins of Health and Disease (DOHaD), requires clinical providers of reproductive medicine to examine the potential role of fetal/neonatal programming on adult pathology affecting fertility. This live course will present experimental evidence and clinical observations linking developmental toxicant exposure to reproductive disorders. Additionally, the faculty will discuss the significance of epigenetic programming on the heritability of toxicant-associated disorders and will describe the influence of nutrition on reducing the impact of a previous toxicant exposure. Finally, this course will present the emerging evidence that environmental toxicant exposure of animals and humans impacts adult reproductive function for multiple generations and will provide specific recommendations for providers to optimize patient care in fertility clinics.
  25. 25. 25 46TH ANNUAL POSTGRADUATE PROGRAM ACGME Competency Medical knowledge LEARNING OBJECTIVES At the conclusion of this course, participants should be able to: 1. Evaluate the evidence implicating environmental toxicant exposure at different stages of life to disruption of adult reproductive tract function and development of disease. 2. List specific toxicants, their routes of exposure and mechanisms of action which may negatively impact reproductive processes in humans. 3. Describe the DOHaD hypothesis and its relevance to reproductive medicine. 4. Discuss how nutrition may modify the negative impact of a prior toxicant exposure and improve reproductive outcomes. 5. Develop improved strategies for ascertaining a couple’s exposure history relevant to infertility treatment. ULTRASOUND IMAGING IN REPRODUCTIVE MEDICINE: A PRACTICAL APPROACH Course PG19 (Sunday) Developed in Cooperation with the American Institute of Ultrasound in Medicine and the Imaging in Reproductive Medicine Special Interest Group FACULTY Laurel A. Stadtmauer, M.D., Ph.D., Chair NEEDS ASSESSMENT AND COURSE DESCRIPTION Ultrasound and ultrasound-guided procedures have become integral components, not just of assisted reproductive technology (ART), but also in the day-to-day practice of reproductive medicine, infertility and gynecology. In 2009, new practice guidelines for ultrasound in reproductive medicine were published by the American Institute of Ultrasound in Medicine (AIUM) and in collaboration with the American Society for Reproductive Medicine (ASRM). Surveys of members of the Society for Reproductive Endocrinology and Infertility, the Imaging Special Interest Group and ASRM have revealed a strong desire for CME credits in ultrasonography that would prepare reproductive medicine professionals and gynecologists for accreditation by the AIUM. In addition, there is an interest in training and credentialing reproductive nurses and nurse practitioners to perform limited ultrasounds in the office. The objective of this course is to provide comprehensive survey of the use of ultrasonography in the female pelvis for physicians and other healthcare providers who use gynecologic ultrasonography. A practical problem-solving approach will be implemented with case presentations. The faculty will critically review the application of ultrasonography to the infertility evaluation, diagnosis, treatments and complications as a way to maximize ART success. Ultrasound has helped in the early pregnancy evaluation and monitoring as well as in assessing pregnancy complications. Many other gynecologic findings on ultrasound such as congenital uterine anomalies, ovarian masses, tubal disease and other uterine pathologies will be discussed along with their impact on fertility and the decision for surgery. A variety of reproductive problems throughout the reproductive lifespan, from puberty through menopause, will be addressed from an ultrasound perspective. Newer technologies with current or potential applications, such as 3-dimensional (3-D) ultrasound, Doppler, and cost-effective use of CT- and MRI-guided procedures will also be covered. There will be interactive discussion of cases and controversies, and participants will also have the opportunity to learn practical applications and manipulate 3-D images. This course will fulfill CME requirements for AIUM credentialing. ACGME Competency Patient care LEARNING OBJECTIVES At the conclusion of this course, participants should be able to: 1. Summarize the appropriate use of ultrasonography in the evaluation of infertility, uterine abnormalities and the pathology of the reproductive tract. 2. Describe the proper assessment of early pregnancy and list findings on early pregnancy assessments that are associated with poor outcome. 3. Discuss the importance of 3-D ultrasonography in reproductive medicine, and the importance of Doppler blood flow assessment in reproductive medicine and gynecology. 4. Evaluate patients with pelvic pain, abnormal bleeding and adnexal masses using a practical approach. 5. Evaluate when surgical intervention is needed, when cancer is suspected and when imaging procedures can be performed to treat abnormalities on ultrasound.
  26. 26. 26 GLOBAL FAMILY PLANNING: THE KEY TO ACHIEVING MILLENNIUM DEVELOPMENT GOALS Course PG20 (Sunday) 46TH ANNUAL POSTGRADUATE PROGRAM Developed in Cooperation with the Contraception Special Interest Group FACULTY Alison Edelman, M.D., M.P.H., Chair NEEDS ASSESSMENT AND COURSE DESCRIPTION Unintended pregnancies continue to be at epidemic levels in the United States and worldwide. Unsafe abortion continues to be one of the top killers of women worldwide. The use of long-acting, reversible and permanent contraceptive methods prevent both pregnancies and abortions. One important barrier to contraceptive use is lack of knowledge and hands-on experience among healthcare providers on “best practices” for contraceptive care. In addition, providers lack the skills for safe abortion care including postabortion and miscarriage management. The Contraception Special Interest Group determined that a postgraduate course with a hands-on component would benefit reproductive endocrinologists, general obstetrician-gynecologists, general internists, family medicine providers, and nurse practitioners. The topics to be covered in this live course include: achieving millennium development goals (MDG) in the current world situation; family planning and the environment; postpartum/postabortion contraception; transcervical and minilaparotomy sterilization; natural family planning; medical management of spontaneous abortions, postabortion care, and safe abortion care; manual vacuum aspiration (MVA) from biopsies, retained placentas, to abortions; resources for the clinician; medical eligibility criteria from the World Health Organization and the Centers for Disease Control; and novel, developing contraception methods. The hands-on component will allow participants to improve clinical skills in postpartum/postabortion intrauterine device (ppIUD) insertion, Essure/Adiana, MVA, transcervical and minilaparotomy permanent contraception, and dilatation and evacuation. ACGME Competency Medical knowledge LEARNING OBJECTIVES At the conclusion of this course, participants should be able to: 1. Analyze the current world situation, MDG goals and environmental issues related to population and family planning and recommend resources that aid the clinician in the provision of contraceptive care. 2. Explain family-planning methods with the greatest impact for reducing maternal morbidity and mortality (use of ppIUD, permanent contraception, and novel methods being developed). 3. Apply the acquired skills to perform ppIUD insertion and transcervical and minilaparotomy permanent contraception. 4. Describe safe and standardized regimens for the medical management of incomplete abortion, miscarriage or undesired pregnancy. 5. Describe and demonstrate the use of manual vacuum aspirator for gynecologic, obstetric and family planning indications. SAFE IN VITRO FERTILIZATION Course PG21 (Sunday) Developed in Cooperation with the Society for Assisted Reproductive Technology FACULTY Valerie L. Baker, M.D., Chair NEEDS ASSESSMENT AND COURSE DESCRIPTION Although assisted reproductive technology (ART) is a widely-used treatment that often leads to the birth of healthy children without serious maternal complications, concerns have been raised about increased risk of certain adverse outcomes for both the mother and the offspring. ART has been associated with higher rates of compromised fetal growth, preterm delivery, maternal complications such as preeclampsia, and possibly congenital anomalies and epigenetic disorders. Some risks of adverse outcomes associated with ART are likely attributable to the underlying infertility. However, it is important for clinicians to be aware of ART risks that may be associated with the treatment itself. Some adverse outcomes associated with ART may be attributable to multiple gestation, laboratory practices, or the unphysiologic maternal state in which pregnancy typically begins with ART. This live course will equip clinicians to better inform patients about the risks and benefits of various aspects of ART. Faculty will provide recommendations on how to mitigate the risks, including optimization of ovulation induction, and maximize the safety of ART. Other topics covered include an up-to-date understanding of the benefits and risks of various laboratory procedures and ART treatment for patients with medical problems. ACGME Competency Patient care
  27. 27. 27 46TH ANNUAL POSTGRADUATE PROGRAM LEARNING OBJECTIVES At the conclusion of this course, participants should be able to: 1. Choose individualized ovulation stimulation protocols with consideration given to both potential short-term and long-term consequences for the mother and fetus. 2. Explain the risks and benefits of laboratory practices such as extended culture, embryo biopsy at different stages, oocyte cryopreservation and open versus closed vitrification. 3. Provide recommendations that will reduce the risk of multiple gestation while still maintaining a high live-birth rate. 4. Advise patients at increased risk of pregnancy complications. THE SIGNIFICANCE, IMPLICATIONS AND HERITABILITY OF MALE INFERTILITY AS A DISEASE Course PG22 (Sunday) Developed in Cooperation with the Society for Male Reproduction and Urology FACULTY Paul J. Turek, M.D., Chair NEEDS ASSESSMENT AND COURSE DESCRIPTION The clinical significance of the male factor infertility evaluation has been underestimated to date. Given the well-described associations between male infertility and a) underlying concurrent medical conditions, b) genetic anomalies, c) environmental exposures and d) future cancers, male factor infertility is clearly a disease of clinical and epidemiological significance. However, it is estimated that less than one in four infertile males in the United States receives the recommended male factor evaluation as part of the couple infertility assessment. Educating clinicians about the implications of male factor infertility is the first step in changing clinical behavior that incorporates the male factor evaluation into every couple’s assessment. Through a thorough discussion of our current understanding of the medical, genetic and epidemiologic issues associated with male factor infertility, this course seeks to raise awareness and change practice patterns of clinicians who care for infertile couples. By emphasizing that male infertility is a window into both current and future health of the individual (i.e., is a biomarker of health), this course will: improve clinicians’ level of understanding and knowledge of relevant lifestyle issues and behaviors that are associated with infertility, help clinicians precisely identify those individuals at risk for genetic infertility, and enable clinicians to better educate their patients regarding the health risks associated with a male infertility diagnosis. It is our hope that this course will enlighten clinicians, laboratory technicians and researchers alike of the full impact of male infertility on the health, quality of life and longevity of affected individuals. ACGME Competency Patient care LEARNING OBJECTIVES At the conclusion of this course, participants should be able to: 1. Describe three metabolic or hormonal disorders that are associated with male factor infertility. 2. List the clinical criteria that define men at risk for genetic infertility due to Y chromosome deletions or karyotype anomalies. 3. Delineate four lifestyle, occupational or exposure risk factors linked to male factor infertility. 4. List two cancers that are more likely to occur in infertile men than otherwise healthy men AFTER a diagnosis of male factor infertility. 5. Explain two genetic or medical conditions in offspring that are associated with severe male factor infertility or older paternal age.
  28. 28. 28 46TH ANNUAL POSTGRADUATE PROGRAM TRAINING PEOPLE IN LOW-COST INFERTILITY AND ART TREATMENT Course PG23 (Sunday) Developed in Cooperation with the International Federation of Fertility Societies FACULTY Ian D. Cooke, M.B., FRCOG, F.Med.Sci., Chair NEEDS ASSESSMENT AND COURSE DESCRIPTION Access to infertility diagnosis and treatment is extremely poor in the developing world. There are too few clinics or private doctors interested in and competent to manage infertility problems, no adequate referral systems, and few trained staff. National health services provide few treatments as many countries struggle with major disease, such as human immunodeficiency virus (HIV), malaria and tuberculosis (TB). Available private services are usually too costly for the average patient and can result in catastrophic expense. The most common cause of infertility in developing nations is tubal obstruction from infection, either chlamydia, gonorrhea or postpartum or postabortion sepsis, where the only realistic management plan includes in vitro fertilization (IVF). However, public health education on reproduction is minimal and infertility is surrounded by fear and superstition and compounded by local religious attitudes. Treatment options are not widely known and sophisticated methods, such as assisted reproductive technology (ART), are not available. Management of infertility needs to be conducted within a framework of adequate reproductive health services, so that preparation for pregnancy, the pregnancy and the delivery are competently managed, in places where skilled attendance at delivery may not be standard practice. Health professionals, either nationals of low resource economies or altruistic academics from developed countries, wanting to implement infertility treatments and ART in the developing world must understand the problems and acquire the competence to approach them in ways that are cost-effective for their region and not simply attempt to transfer systems developed for more-affluent environments. This live course will describe how to develop assisted-conception services in low-resource environments. Discussion will cover how to find suitable laboratory space, provide robust equipment and maintain it in working order, maintain lab records with a view to quality control, trouble shoot, and use the laboratory data to develop the service. Identifying potential patients, patient screening, meeting with both partners, and treatment prior to ART will be emphasized as well as the principles of preparation for pregnancy and obstetric care. The indications for intra-uterine insemination (IUI) and IVF (and the need for intra-cytoplasmic sperm injection [ICSI]) will be elaborated in the context of education about reproductive biology, pathology and specific treatment for the couple and the implications for public health education. Minimal ovarian stimulation will be discussed in the context of avoiding hyperstimulation and multifetal pregnancy. The critical role of ultrasound will be presented with technical details of appropriate apparatus and the skill requirements and methods for acquiring them will be presented. The role of various staff members will be elaborated and include quality standards. Finally, an appraisal of the financial viability of developing an assisted-conception clinic and the use of data obtained from such a clinic will be detailed. Data can be reported to national and international registries and used to attract patients and influence policy related to service provision at a national level, thus helping to extend local health service to a greater proportion of the population in accordance with the World Health Organization rubric of appropriately-stratified healthcare. ACGME Competency Systems-based practice LEARNING OBJECTIVES At the conclusion of this course, participants should be able to: 1. Explain the rationale for providing assisted-conception services in low-resource environments. 2. Develop a clinic offering suitable ART services and competently manage patients in such a setting. 3. Specify the steps required for financial viability and for quality data retention and reporting. 4. Develop educational programs suitable for patients, the general public and health service administrators.
  29. 29. 29 46TH ANNUAL POSTGRADUATE PROGRAM PGD IMPACT ON ART EFFICIENCY WITH INTRODUCTION OF MICROARRAY TECHNOLOGY FOR 24 CHROMOSOME ANEUPLOIDY TESTING Course PG24 (Sunday) Developed in Cooperation with the Preimplantation Genetic Diagnosis Special Interest Group FACULTY Anver Kuliev, M.D., Ph.D., Chair Santiago Munné, Ph.D., Co-Chair NEEDS ASSESSMENT AND COURSE DESCRIPTION At least 50% of oocytes and embryos from in vitro fertilization (IVF) patients of advanced reproductive age are chromosomally abnormal, contributing significantly to infertility and pregnancy loss. Because of the present controversy on the impact of preimplantation genetic testing (PGT) for aneuploidies on the improvement of assisted reproductive technology (ART), there is a need for the development of efficient and robust methods for preselection of aneuploidy-free embryos for transfer. The available methods based on morphological criteria are not sufficient for selection of embryos with the highest developmental potential. The previous methods for aneuploidy testing were based on the fluorescence in situ hybridization (FISH) technique, which has an important limitation of not detecting abnormalities of all the chromosomes. In addition, the procedure is predominantly applied at the cleavage stage, which is compromised by the high risk of mosaicism that may contribute to false positive and false negative results. This live course is aimed at increasing the knowledge and competence of fertility specialists and laboratory professionals, but will also be of interest to a wider audience, taking into consideration the recent controversy regarding preimplantation aneuploidy testing. Faculty will introduce microarray technology, which tests for all 24 chromosomes, and the application of this technology to different biopsy materials, including polar bodies, blastomeres and blastocysts. Participants will analyze the different platforms for 24 chromosome aneuploidy testing and review data on the clinical outcome of the application of this methodology. ACGME Competency Patient care LEARNING OBJECTIVES At the conclusion of this course, participants should be able to: 1. Evaluate the contribution of the FISH technique to the false positive and false negative results and the impact on the clinical outcome data. 2. Describe the practical application of preimplantation 24 chromosome testing to PGD for chromosomal disorders. 3. Explain the importance of selection of the optimal biopsy procedure for the highest accuracy of preimplantation 24 chromosome aneuploidy testing. 4. Discuss the expected efficiency of 24 chromosome aneuploidy testing, depending on the type of microarray technique used and the differences of the applied biopsy procedures. MANAGING MENOPAUSE...WITH FINGERS ON THE PULSE AND EYES ON THE FUTURE Course PG25 (Sunday) Developed in Cooperation with the Menopause Special Interest Group FACULTY Lubna Pal, M.B.B.S., M.S., Chair NEEDS ASSESSMENT AND COURSE DESCRIPTION Menopausal management has transformed over the past decade, with an obvious shift from a relatively liberal use of exogenous hormones in the pre-Women’s Health Initiative era, to a more cautious stance regarding the place of menopausal hormone therapy in the management of menopause-related symptoms. Concerns regarding long-term implications of menopausal hormone therapy appear to underlie this change in clinical practice. Although today’s clinicians are sensitized to the unique needs of an individual menopausal woman, and are better aware of the expanding spectrum of therapeutic options, the management paradigms still remain ambiguous for many and the dichotomy of findings from observational studies and randomized trials continue to confuse patients and providers alike. Easy access to “proverbial” and “anecdotal” information via the Internet has magnified the complexity of clinician-patient discussions and frequently influences patient choices and decisions related to menopause management. Early diagnosis and advances in the field of oncology are contributing to increasing numbers of relatively young cancer survivors who are experiencing premature ovarian insufficiency after chemo-radiation therapy. Clinical evidence suggests that the health burden attributable to premature cessation of ovarian function in this population may not be adequately appreciated or addressed. It is thus essential for clinicians who care for young female cancer survivors to understand the needs and concerns relating to iatrogenic menopause in this unique population. Today’s targeted approach to clinical practice may restrict a clinician’s ability to explore an individual patient’s non-verbalized concerns, an aspect that is of particular relevance for women transgressing the spectrum of peri and early menopause. In addition to being cognizant of climacteric symptoms and the available strategies for symptom control, providers should also be prepared to treat the needs of perimenopausal and early menopausal women, including preventive care, risk quantification and risk reduction, and contraceptive and procreative preferences. The future of menopausal management, driven by concepts of selective estrogen receptor modulators (SERMs), tissue selective estrogen complexes (TSECs) and stem cell therapy, promises a dynamic terrain that is likely to redefine how we care for the perimenopausal and menopausal woman.
  30. 30. 30 46TH ANNUAL POSTGRADUATE PROGRAM The decision to offer a particular management strategy is dictated by the patient’s clinical presentation and a thorough evaluation of the individualized risk versus benefit profile. Large gaps exist between patient expectations and provider competency to help guide patient decision making. Consistent with the literature, surveys conducted by the American Society for Reproductive Medicine (ASRM) in 2009 and 2011 members identified personal practice gaps in the treatment of menopause-related issues, and requested educational activities to specifically address their understanding of individualized treatment approaches. The goal of this live course is to offer a critical review of evidence-based recommendations that will give clinicians the skill set to provide comprehensive, competent care to women making the transition into menopause. ACGME Competency Patient care LEARNING OBJECTIVES At the conclusion of this course, participants should be able to: 1. Individualize risk assessment and recommend risk reduction strategies for peri and postmenopausal women, and develop optimal, individualized management strategies of contraceptive and procreative needs in the perimenopausal population. 2. Compare and contrast the efficacy, safety and side effects of available therapies (hormonal and non-hormonal) for common menopausal disorders, and design treatment plans for women with diverse disease states and of different ages with menopausal symptoms and/or osteoporosis. 3. Distinguish the unique needs and risks of women experiencing unnatural menopause (premature, surgical or following chemo-radiation), and develop individualized management strategies. 4. Explain emerging concepts in menopausal medicine (e.g., SERMs, TSECs and stem cell). HYSTEROSCOPY Course PG26 (Sunday) Developed in Cooperation with the Society of Reproductive Surgeons FACULTY Steven F. Palter, M.D., Chair FUTURE ASRM ANNUAL MEETINGS October 18-22, 2014 Honolulu, HI Hawaii Convention Center October 17-21, 2015 Baltimore, MD Baltimore Convention Center Developed in Cooperation with the American Association of Bioanalysts FACULTY Tammie Schalue, Ph.D., H.C.L.D., E.L.D., Chair CLINICAL EMBRYOLOGY AND ANDROLOGY FOR PHYSICIANS Course PG27 (Saturday & Sunday) Two-Day Course Saturday, October 12, 2013 - Sunday, October 13, 2013
  31. 31. 31 IFFS/ASRM 2013 Scientific Program Needs Assessment and Description The field of reproductive medicine is evolving rapidly with advances reflecting the multicultural contributions of the global community of healthcare professionals. The IFFS Scientific Committee and the ASRM Scientific Program Committee se- lected as their theme for the 2013 conjoint meeting “Transforming Reproductive Medicine Worldwide” to emphasize inter- national collaborative efforts to improve every patient’s ability to fulfill his or her reproductive destiny. Reproductive health- care is challenged globally by technology, ethics, clinical skill, social customs, religious beliefs, emotions, legal restrictions and cost. Clinicians, scientists and allied health professionals must improve their ability to navigate these uncharted ter- ritories in order to provide optimal care for their patients. The educational activities of the 2013 postgraduate and scientific programs are designed to enhance the medical and scientific knowledge, clinical and laboratory competence and profes- sional performance of the healthcare team in helping patients achieve their goals with regards to reproduction. The program committees have designed postgraduate courses, plenary lectures, symposia, interactive sessions, debates, roundtable discussions and oral and poster free-communication sessions to provide participants with a variety of formats and venues to teach and learn, discuss and debate, and give and receive new information, insight and skill. New to ASRM will be the popular IFFS trilogy format in which three speakers discuss the basic, translational and clinical aspects of a particular topic. The educational and program committees have identified educational needs through gap analyses for education in the areas of male and female infertility, assisted reproductive technology, andrology, endome- triosis, reproductive perturbations by environmental toxicants, sexuality, menopause, contraception, gamete and embryo biology, polycystic ovary syndrome, fibroids, regenerative medicine and stem cell biology, and access to reproductive care in low-resource regions. Experts from around the world will present the most recent cutting-edge evidence regarding diagnosis and treatment of reproductive problems. The 2013 IFFS/ASRM conjoint meeting will provide abundant educational opportunities for reproductive endocrinolo- gists, gynecologists, urologists, family practitioners, internists, embryologists, andrologists, nurses, psychologists, social workers, geneticists, and practice managers. Both the postgraduate and scientific programs will include mentored, hands- on training for those reproductive surgeons wishing to enhance their skills in minimally invasive and robotic surgery. The goal is for every professional in the field of reproductive medicine and biology to leave the meeting as a better practitioner stimulated to make new discoveries that will advance reproductive healthcare. Learning Objectives At the conclusion of the postgraduate and scientific programs, participants should be able to: 1. Compare and contrast clinical approaches to fertility care in resource-rich and low-resource regions. 2. Summarize the latest scientific advances in the biology of gamete and embryo development, fibroids, endometrio- sis, stem cells and polycystic ovary syndrome. 3. Discuss optimal methods for producing, culturing, assessing, selecting and cryopreserving human embryos. 4. Design evidence-based interventions to treat male reproductive disorders. 5. Implement protocols for preimplantation genetic testing to prevent propagation of genetic diseases in assisted reproductive technologies. 6. Counsel infertile patients regarding the costs, both emotional and financial, of using the latest medical therapies to build a family. 7. Assist postmenopausal women in coping with vasomotor symptoms, bone loss, mood disorders and sleep distur- bances. 8. Recommend the most appropriate contraceptive methods for patients in different physiological, cultural and finan- cial circumstances.

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