21st Annual International Epilepsy Symposia
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    21st Annual International Epilepsy Symposia 21st Annual International Epilepsy Symposia Document Transcript

    • 21st Annual InternationalEpilepsy SymposiaMarriott Cleveland Downtown at Key CenterCleveland, OHClinical Epileptology Review and UpdateOctober 19-20, 2012Pathology-driven Approach to Epilepsy Surgery:Current State and Future DirectionsOctober 21-24, 2012International Neuroethics Conference: Brain Matters 3October 24-25, 2012 www.ccfcme.org/epilepsy12 In Collaboration With:
    • General InformationTarget AudienceThe symposia are designed for adult and pediatric neurologists andepileptologists, neurosurgeons with an interest in epilepsy surgery inadults and children, psychiatrists, clinical neuropsychologists, socialworkers and other expert caretakers of patients with epilepsy acrossall age groups.LocationCleveland Marriott Downtown at Key Center127 Public SquareCleveland, OH 44114216-696-9200A block of rooms has been reserved at the Cleveland MarriottDowntown at Key Center at the special group rate of $169 per nightplus tax. Reservations must be made by Tuesday, September 4,2012, in order to quality for this rate.InformationFor further information about this activity, contact Martha Tobin atLocal: 216-445-3449Toll Free: 800-223-2273 x53449Email: tobinm@ccf.orgDeadline for Registration and Cancellation AccreditationRegister at www.ccfcme.org/epilepsy12. Deadline for registration The Cleveland Clinic Foundation Center for Continuing Educationfor the symposium is 5:00 pm (EST), Monday, October 15, is accredited by the Accreditation Council for Continuing Medical2012. A request for a refund must be received in writing by October Education to provide continuing medical education for physicians.5, 2012. No refunds will be given after October 5, but registration istransferable through October 15, 2012. A $50 cancellation fee will be The Cleveland Clinic Foundation Center for Continuing Educationdeducted from the refund for all cancellations. designates this live activity for a maximum of 59.75 AMA PRA Category 1 Credits. Physicians should claim only the creditIf you register by mail, please allow up to three weeks for your commensurate with the extent of their participation in the activity.registration to be processed.For questions about registration, please call 216-448-0777 or email Participants claiming CME credit from this activity may submit thecmeregistration@ccf.org. credit hours to the American Osteopathic Association for Category 2 credit. Faculty Disclosure Statement The Cleveland Clinic Foundation Center for Continuing Education has implemented a policy to comply with the current Accreditation Council for Continuing Medical Education Standards for Commercial Support requiring resolution of all faculty conflicts of interest. Faculty declaring a relevant commercial interest will be identified in the activity syllabus. Americans with Disabilities Act The Cleveland Clinic Foundation Center for Continuing Education fully intends to comply with the legal requirements of the Americans with Disabilities Act. If you need assistance, please notify Monet Smith at 216-444-9380 at least two weeks prior to the activity.
    • Review and Update on Clinical EpileptologyOctober 19-20, 2012Course Overview Learning ObjectivesThis course will focus on updated knowledge that has directimpact on the practice and treatment of patients with epilepsy. 1. Recognize molecular and genetic mechanisms of epilepsyTopics will cover the latest understanding of mechanisms, 2. Review the spectrum of epilepsy in neurocutaneous disorderssyndromes, antiepileptic drugs, EEG techniques, psychiatric 3. Discuss the use of antiepileptic drugsissues, and patient management involving medications, 4. Review the treatment of status epilepticusneurostimulators, and surgery. 5. Describe the recognition and management of psychiatricThe format of the course will be structured with daily self- comorbidities in patients with epilepsyassessment examinations, to qualify for self-assessment 6. Discuss the management of non-epileptic seizuresexamination credits that fulfill the Neurology Maintenance of 7. Discuss the management of seizures in special populations:Certification Part II requirements for continued certification as in the elderly and in pregnancygranted by the ABPN. Test questions will be answered in talks 8. Review the application of neurostimulation in epilepsywith feedback using an audience response system. 9. Discuss successes and failures in epilepsy surgery 10. Illustrate the use of EEG and imaging in epilepsy Course Schedule Friday, October 19, 2012 Saturday, October 20, 2012 8:00-9:00 am Self-Assessment Examination (SA CME) 8:00-9:00 am Self-Assessment Examination (SA CME) 9:00 am–12:15 pm Morning Session 9:00 am–12:15 pm Morning Session Pathogenesis of Epilepsy Practice Guidelines and Parameters in Epilepsy Neurocutaneous Syndromes and Epilepsy Management of Non-Epileptic Seizures Genetics in Epilepsy Evaluation and Treatment of Psychiatric Co-morbidities Pharmaco-kinetics, -dynamics, and -genomics of drugs Pregnancy and Epilepsy 1:15–6:00 pm Afternoon Session 1:15–6:00 pm Afternoon Session EEG Pearls Neuroimaging Pearls in Epilepsy Newer Antiepileptic Drugs Epilepsy in the Elderly Changing and Adding Antiepileptic Drugs MEG and EEG Source Modeling Treatment of Acute Repetitive Seizures and Status Epilepsy Surgery: Successes and Failures Epilepticus Neurostimulation in Epilepsy EEG in the ICU and Hospital Epilepsy Case Management Focal Epilepsy from the Operculum, Insula, Parietal Lobe Case discussion Case discussion 6:00 pm Adjourn 6:00 pm AdjournApplication for Self-Assessment CME (4 credits) has been made to the American Board of Psychiatry and Neurology. Approval is pending.
    • Pathology-driven Approach to Epilepsy Surgery: Current State and Future DirectionsOctober 21-24, 2012Conference Overview Learning ObjectivesThese unique epilepsy symposia will provide a comprehensive 1. Define each of the major pathological substrates underlyingand at the same time refreshing approach to the evaluation surgically-remediable epilepsiesand surgical management of adult and pediatric patients withuncontrolled seizures. Specifically, the symposia will focus on 2. Review the histopathological identification of each substratethe current state and future directions of presurgical evaluations 3. Review the neuroimaging features and advancements inand epilepsy surgery guided by our renewed understanding of the identification of each pathologyunderlying pathology in each individual. With the widespread use 4. Review the current role of EEG, video-EEG and semiology tailoredof noninvasive and invasive evaluations and epilepsy neurosurgery to presurgical evaluationthe need arises to better define the pathological substrate 5. Review advanced techniques in clinical neurophysiology, andand tailor our investigations, and expectations accordingly. structural as well as functional neuroimaging that may enhanceThis goal will be accomplished by detailing the structural and identification and understanding of each pathologyhistopathological identification of each epileptic substrate. We 6. Review indications, techniques and complications of differentwill then review neuroimaging, electro-clinical and anatomo- methods of invasive monitoring as these relate to the underlyingfunctional, typical and atypical, presentations of each pathological pathological substratesubstrate in adult and pediatric patients with medically-intractable 7. Review tailored surgical decision-making and management ofepilepsies. We will then review the process of individualized each individual patientsurgical decision-making based on illustrative case discussions. 8. Discuss our understanding of successes and failures of epilepsy surgeryConference ScheduleSunday, October 21 IIc. Pediatric 4:30–5:00 pmI. Introduction/Overview 7:30–9:30 am Hippocampal sclerosis in children; age-based differences in imaging, • Pathology-based epilepsy surgery or epilepsy surgeries? semiology, comorbid conditions and surgical management • Contribution of pathological studies to Epilepsy Surgery: Past, IId. Surgical Case-based Discussion 5:00–7:00 pm present and future. Case #1: Dominant mesial temporal lobe epilepsy with preserved • Contribution of Imaging to Epilepsy Surgery: Past, present and material specific memory future. Case #2: Pediatric case of intractable hippocampal sclerosis Case #3: Bilateral hippocampal sclerosis on MRI; discussion ofII. Hippocampal Sclerosis nonresective approachesIIa. Structural 10:00–11:30 am • Anatomy of the temporal lobe and its connections: implications for EEG/semiology/management; epileptogenic network in HS BYOCD Dinner 7:30-9:30 pm • Histology and histopathology of the hippocampus: what is Bring Your Own Case Discussion hippocampal sclerosis? Is HS a single pathological diagnosis? How many types of HS do we have? What is beyond the histology? Are This year the Cleveland Clinic Epilepsy Surgery Symposium there molecular markers? organizing committee invites meeting attendees to submit • Typical and atypical MRI findings. How normal is a normal MRI in interesting or challenging surgical cases that have been evaluated hippocampal sclerosis? (The role of post-processing techniques in and managed at their home institutions. The cases should highlight optimizing the diagnosis/evaluation strategies of mesial temporal a particular clinical, EEG, imaging or histopathological presentation lobe epilepsies) that would be of considerable interest to the audience.The Fourth Dudley S. Dinner Distinguished Epileptologist’s Each case should include a brief description of demographics,Luncheon Lecture 12:00–1:00 pm epilepsy history and electroclinical presentation, without any patient identifiable information, lasting for 5 minutes or less andIIb. Electro-functional 1:30–4:00 pm limited to a total of 5 slides. Meeting participants will have the • The “classical” electroclinical presentation of hippocampal opportunity to present their case, which will be followed by an sclerosis (are there specific historical, EEG and imaging features)? interactive discussion with faculty and meeting attendees. Significance of distribution of interictal spikes in adults and children • Red flags and diagnostic approach – when do you need more data? A total of 10 cases will be selected by the organizing committee to How can HS exhibit itself as HS, and non-HS as HS, and how to be reviewed in this format. address these issues? • The cognitive impact of hippocampal sclerosis, early versus late Cases may be submitted at surgical intervention, and impact of epilepsy surgery – how do we www.ccfcme.org/Epilepsy12 identify at-risk patients for memory decline and what does memory decline mean for the patient? Deadline for submission is September 1, 2012. • How can we use pre-operative imaging to assess cognitive and memory function? • Can early intervention prevent bilateral HS or disease progression?
    • Special Luncheon Lecture 12:45-1:20 pmMonday, October 22 Lessons Learned From Surgery in Epilepsy Associated withIII. Focal Cortical Dysplasia 8:00 am–12:30 pm Neurocysticercosis: A Model of Acquired Epilepsy?IIIa. Structural V. Vascular Destructive Lesions & Vascular Malformations • Embryology of Cortical Dysplasia and key differences between 1:30–6:30 pm congenital and acquired dysplasia • Histopathology of Cortical Dysplasia Va. Structural • MRI in Cortical Dysplasia: What do we see? What we do not see • Imaging-histopathological correlations of vascular/ hypoxic and why? How can we see what we do not see? MRI techniques destructive lesions associated with epilepsy: Ulegyria, major structural imaging (post-processing & high field strength); how can telencephalic destructions and the transition to normal tissue we get better? • Coping with early destruction: How the brain reorganizes functionIIIb. Electro-functional and why it matters for epilepsy surgery? • EEG and imaging correlates of focal cortical dysplasia Vb. Electro-functional • Functional correlates of Cortical Dysplasia • Clinical and electrographic hallmarks of the neurological and • Epileptogenic networks in cortical dysplasia: in situ epileptogenic epileptic pictures networks • Delineating the relevant epileptogenic and functional cortex • Choice of invasive technique(s) associated with encephalomalaciaIIIc. Pediatric Vc. Pediatric Considerations Cortical dysplasia in the very young: age-based differences in Inducing favorable plasticity through seizure control and resection of imaging, electroclinical presentation and surgical management epileptogenic abnormalitiesIIId. Surgical Case-based discussion 1:30–3:30 pm Vd. Special Considerations – Vascular Malformations Case #1: Focal Cortical Dysplasia (FCD) in eloquent cortex Cavernous angiomas imaging findings, electroclinical presentation Case #2: Pediatric case of intractable FCD and management: when a lesionectomy is enough and when not Case #3: Reoperation in FCD Ve. Surgical Case-based Discussion 5:00–6:30 pmIIIe. Special considerations in MRI-negative patients Case #1: Presurgical evaluation and surgical approach to patient with 4:00–6:30 pm temporal lobe epilepsy in the setting of temporo-polar cavernous (A) Structural angioma in the dominant hemisphere What are the pathologies of nonlesional epilepsy? Does it exist? Case #2: Presurgical evaluation and surgical approach to a patient Markers of nonlesional epilepsies? with lateral temporoparietal encephalomalacia and possible (B) Electro-functional hippocampal sclerosis • Neurophysiology: Noninvasive EEG (including high density arrays/ Case #3: Epilepsy in a child with large hemispheric encephalomalacia High Frequency Oscillations), EEG-triggered fMRI and MEG: but preserved sensorimotor function contributions & limitations in nonlesional epilepsies • Nuclear/molecular imaging: contributions & limitations in nonlesional epilepsies Special Combined Epilepsy and Ethics Lecture • Post-processing neuroimaging techniques Cross-cultural Understanding of Seizures 6:45–7:45 pm • Approach to nonlesional epilepsies of elusive/genetic etiology: are focal features a clue to surgical candidacy? Wednesday, October 24 VI. Preferential Pediatric Pathologies 8:00–11:30 amTuesday, October 23 • Hemispheric dysplasia & hemimegalencephaly: pathologicalIV. Brain Tumors 8:00 am–12:30 pm and imaging findings, electroclinical presentation and surgicalIVa. Structural management. • Histopathology of tumoral epilepsies: what makes tumors epileptic? • Sturge Weber syndrome: pathological and imaging findings; focal • Imaging: Can we see the “epileptic” part of the tumor? versus radical surgery. • Tuberous Sclerosis: pathological and imaging findings,IVb. Electro-functional electroclinical presentation and surgical management. • The approach to a patient with tumor and intractable epilepsy: How • Rasmussen Encephalitis: pathological and imaging findings, complete or thorough should the evaluation be? Is VEEG monitoring electroclinical presentation and surgical management. needed? • Hemispherectomy: surgical techniques, indications for • Where is the epileptogenicity in tumors? How to define it? disconnections and choice of the techniqueIVc. Pediatric • Outcomes and their determinants following hemispheric Brain tumors unique to children: electroclinical presentation, imaging disconnections findings and managementIVd. Surgical Case-based discussion 11:00–12:30 pm Surgical Case-based discussion 11:30–1:30 pm Case#1: Patient with epilepsy in the setting of an infiltrative or non- Case#1: Tuberous Sclerosis with invasive recordings resectable tumor: Can surgery be helpful? What is the best surgical approach and management? Case#2: Sturge Weber syndrome with focal resection Case#2: Pediatric case of intractable tumoral epilepsy Case #3: Rasmussen encephalitis with initial medical management Case #3: Case of epilepsy surgery versus tumor surgery Adjourn 1:30 pm
    • International Neuroethics ConferenceBrain Matters 3: Values at the Crossroads of Neurology, Psychiatry and PsychologyOctober 24-25, 2012Conference Overview Learning ObjectivesThis conference addresses ethical dilemmas in the treatment and research inconditions with neurological symptomatology but that are without identifiable 1. Create neuroethics research collaborations on conditions with neurological symptomatology,biological correlates/causes. The conditions of interest are often framed as but that have medically unexplained symptomsmedically unexplained symptoms (MUS), non-specific etiologies (NoS), or or are believed to have psychogenicpurely psychological. These diagnoses include, but are not limited to, chronic components.pain disorders, psychogenic movement disorders, conversion disorders, posttraumatic stress disorder, and fibromyalgia. The complexities of suffering 2. Disseminate new synthesis of ideas andand disability experienced by individuals with these conditions are significant; reflections from leading researchers.including exposure to dangerous and futile treatments. Among clinicians, 3. Bring together a unique, diversedisagreement continues over which aspects of these conditions are “all in multidisciplinary group of researchers,one’s head,” either literally or figuratively. Hidden value assumptions about clinicians, and ethicists to foster greatercausation permeate research studies and clinical decisions, and effect collaboration in developing this field.underlying treatment and care of patients. These assumptions have significantinfluence on the obligations, roles, and entitlements for patients and health 4. Create an analysis of ethics in the research andcare providers. Patients who suffer from these conditions are “orphaned” by treatment of Non-Epileptic Seizures, in bothspecialties and largely ignored in bioethics discussions. The plenary speakers pediatric and adult contexts.of this conference will address ethical challenges from a variety of academicdisciplines and medical subspecialties. Presentations will be given by patients,physicians, neuroscientists, and ethicists. Research abstracts will be solicitedboth for oral presentations as well as poster presentations. Conference Schedule Tuesday, October 23 Thursday, October 25 6:45-7:45 pm Evening Pre-conference Lecture: Cross- 8:00 am Plenary 4: Ethical Challenges Relating to Cultural Understandings of Seizures – Lisa Andermann Understanding the Physiology of Volition. What is Free About Free Will? – Mark Hallett Wednesday, October 24 9:30 am Breakout Sessions III 8:00 am Plenary 1: Patients’ Perspectives on Medically A. “Parent-ectomy”/“Child-ectomy” Panel Unexplained Symptoms – Siri Hustvedt and Carmen Paradis B. Accepted Paper C. Accepted Papers 9:30 am Breakout Sessions I A. Adult Psychogenic Nonepileptic Seizures Ethics 11:15 am Plenary 5: Ethical Challenges in Post Traumatic Working Session Stress Disorder and Traumatic Brain Injury in the Military B. Accepted Paper Context – Elspeth Ritchie C. Accepted Papers 1:30 pm Breakout Sessions IV 11:15 am Plenary 2: The Cultural Brain and the A. DSM-V Redefinitions Panel Construction of Self – Grant Gillett B. Accepted Paper C. Accepted Papers 1:30 pm Breakout Sessions II A. Pediatric Psychogenic Nonepileptic Seizures 3:45 pm Plenary 6: Partial Truths, Labels, and Ethics Working Group Responsibilities in Medically Unexplained Symptoms B. Accepted Paper – Richard Kanaan C. Accepted Papers 5:00 pm Adjourn 3:45 pm Plenary 3: Non-Epileptic Seizures, Communication and Ethics – Markus Reuber 5:00 pm Adjourn
    • Call for AbstractsThe Cleveland Clinic Epilepsy Surgery Symposium organizing as well as the opportunity to present their data in a dedicatedcommittee invites meeting attendees to submit abstracts session and ceremony.describing original epilepsy-related research. Our goal is to encourage young researchers in the field of epilepsyThe committee is also happy to announce the institution of the by providing them with an opportunity to showcase and discussCleveland Clinic Epilepsy Research Award. This award is offered to their results with experts in the field, and provide ground for furthermeeting attendees from within the United States and abroad whose investigations.abstracts provide a significant contribution to the Symposium’sgeneral theme and the understanding of epilepsy mechanisms and All other accepted abstracts will be shown in a poster session.treatments. Abstracts may be submitted atFive winners will be selected by the organizing committee. The www.ccfcme.org/EpilSurg12abstracts.winners will have their meeting registration fee waived and will be Deadline for submission is September 1, 2012.provided free accommodation in the meeting hotel’s headquarters,The Fourth Dudley S. DinnerDistinguished Epileptologist’s Lecture Patrick Chauvel, MD of paroxysmal events sources. He has also regarded his work in epilepsy as an opportunity to study normal human cortical Patrick Chauvel is Professor of Physiology physiology: the new Institute includes research teams working on at the Medical School of Aix-Marseille language and memory processing and higher cognitive functions. University (AMU), and Head of Department of Clinical Neurophysiology at the His main contributions have been to develop the concept of Assistance Publique des Hôpitaux de epileptogenic zone as a neural network with peculiar properties of Marseille. He trained in epileptology under synchronization, to make major advances in the pathophysiology of Jean Bancaud, working in Paris, at Hôpital déjà vu and dreamy state, and to decipher the complex patterns of Sainte-Anne and INSERM, with Bancaud frontal lobe seizures.and Talairach at a time when they were laying the foundation formuch of what we know of the dynamics of onset and propagationof focal seizures. Continuing to work in the field of epilepsy Dudley Dinner, MD (1947-2007) camesurgery, he moved to Rennes in the early nineties, then to Marseille to the Cleveland Clinic in 1979 as thein 1997, founding in the town of Henri Gastaut a major Epilepsy first fellow in clinical neurophysiologyCenter oriented towards presurgical investigation of drug-resistant and epilepsy and then joined theepilepsies. He has always devoted his time to developing research Epilepsy Section as staff neurologist andon partial epilepsy pathophysiological mechanisms and treatment, epileptologist. He played a leading role inin close relation with cerebral cortex physiology. He has paid establishing the epilepsy surgery program, evoked potentials and intraoperativemuch attention to interfacing his research field with Cognitive monitoring. Dr. Dinner made manyNeuroscience on the one hand, Biophysics, Signal Processing and valuable contributions to understandingComputational Neuroscience on the other hand. He is currently the the usefulness of the intra-carotid amytalDirector of a new INSERM-AMU Research Unit, named “Institute (WADA) test and the functional anatomy of the supplementary motorof Systems Neuroscience” (U1106), where all these domains are area cortex. He established and directed the sleep disorders center.cooperating through modeling of the clinical reality (http://ins. Dr. Dinner published numerous scientific papers, invited reviews,medecine.univmed.fr). editorials and chapters and also edited the book Sleep and Epilepsy. His vast knowledge and experience was a source of strength for both the epilepsy surgery and sleep programs at the Cleveland Clinic. HeHe is the author or the co-author of more than 270 publications. was very active in the American Clinical Neurophysiology Society andBesides many studies on the clinical semiology of seizures was Associate Editor of the Journal of Clinical Neurophysiology. Hisand its correlation with intracerebral recording (SEEG), he has wisdom and kind, gentle spirit provided guidance and encouragementused EEG signal processing for unraveling the epileptogenic to patients, colleagues, epilepsy fellows and neurology residents.zone organization, and for non-invasive EEG/MEG localization www.ccfcme.org/epilepsy12
    • FacultyCleveland Clinic Conference Invited Guest FacultyDirector Mario Alonso, MD Eric Kossoff, MD México City, Mexico Baltimore, MDImad Najm, MD Lisa Andermann, MD, MA W. Curt LaFrance Jr., MD, MPH Toronto, Canada Providence, RICleveland Clinic Planning Eleonora Aronica, MD, PhD Ilo Leppick, MDCommittee Amsterdam, The Netherlands Minneapolis, MNAndreas Alexopoulos, MD, MPH Fabrice Bartolomei, MD, PhD Giorgio LoRusso, MDPaul Ford, PhD Marseille Cedex, France Milan, ItalyStephen Jones, PhD, MD Selim Benbadis, MD Helio Machado, MD Tampa, FL Ribeirão Preto, BrazilNorman So, MD Andrea Bernasconi, MD Miguel Marin-Padilla, MD Montreal, Canada Hanover, NHCleveland Clinic Faculty Christian Bien, MD Guy McKhann II, MD, PhDJocelyn Bautista, MD Bielefeld, Germany New York, NYWilliam Bingaman, MD Jeff Binder, MD Eliseu Paglioli, MDJuan Bulacio, MD Milwaukee, WI Porto Alegre, BrazilRichard Burgess, MD Ingmar Blümcke, MD André Palmini, MD, PhDRobyn Busch, PhD Erlangen, Germany Porto Alegre, BrazilTatiana Falcone, MD Francesco Cardinale, MD Kurupath Radhakrishnan, MD Milan, Italy Trivandrum, IndiaNancy Foldvary, DO Carlos Carlotti, MD Charles Raybaud, MDJorge Gonzalez-Martinez, MD, PhD Campinas, Brazil Toronto, OntarioAjay Gupta, MD Gregory Cascino, MD Markus Reuber, MD, PhD, FRCPStephen Hantus, MD Rochester, MN Sheffield, United KingdomLara Jehi, MD Fernando Cendes, MD, PhD ´ Aleksandar Ristic , MDPrakash Kotagal, MD Campinas, Brazil Belgrade, SerbiaDeepak Lachhwani, MD Patrick Chauvel, MD Ret. Col. Elspeth Ritchie, MD, MPHDileep Nair, MD Marseilles, France Washington, DCSilvia Neme-Mercante, MD Michael Duchowny, MD Steven Roper, MD Miami, FL Gainesville, FLCarmen Paradis, MD, MA Robert Elwes Esq. Americo Sakamoto, MDRichard Prayson, MD London, United Kingdom Ribeirão Preto, BrazilAndrey Stojic, MD, PhD Stefano Francione, MD, PhD Paul Shkurovich, MDGeorge Tesar, MD Milan, Italy México City, MexicoIrene Z. Wang, PhD Grant Gillett, MD, PhD Roberto Spreafico, MD, PhDDylan Wint, MD Dunedin, New Zealand Milan, ItalyElanie Wyllie, MD Mark Hallett, MD Martin Staudt, MD Bethesda, MD Vogtareuth, GermanyZhong Ying, MD, PhD Bruce Hermann, PhD Laura Tassi, MD Madison, WI Milan, Italy Hans Holthausen, MD Vera Terra-Bustamante, MD Vogtareuth, Germany Ribeirão Preto, Brazil Siri Hustvedt, PhD Paul Van Ness, MD New York, NY Dallas, TX Prasanna Jayakar, MD Tonicarlo Velasco, MD Miami, FL Ribeirão Preto, Brazil Richard Kanaan, MD Richard Wennberg, MD, FRCP(C) London, United Kingdom Toronto, Ontario Matthias Koepp, MD, PhD Howard Weiner, MD London, United Kingdom New York, NY
    • Registration 2012 Epilepsy Symposia Course 020900 Office Use Only October 19-25, 2012 Fee___________ Date___________ Go to: www.ccfcme.org/epilepsy12 M.O.P._________ Once you register online, please do not mail or fax in a registration form. CXL/Fee_______ Complete the information below if registering by mail or fax: PLEASE PRINT First Name Last Name Ml Degree Company Address City State Zip Phone Fax Specialty E-Mail q I require a vegetarian meal Clinical Epileptology Update* and Pathology-driven Pathology-driven International Neuroethics Clinical Epileptology Approach to Approach to Epilepsy Conference: Update* Epilepsy Surgery Surgery Combined Brain Matters 3 Oct 19-20 Oct 21-24 Oct 19-24 Oct 24-25 Check one: A B C D Professional Physicians $295.00 $525.00 $695.00 $195.00 No charge if registering Residents, Fellows, PhD, Nurses, PAs, APNs $149.00 $295.00 $395.00 for A, B or C Student Comprecare #__________________________ $191.75 $342.00 $452.00 $95.00 No charge if registering Cleveland Clinic Alumnus $177.00 $315.00 $417.00 for A, B or C *Application for Self-Assessment CME (4 credits) has been made to the American Board of Psychiatry and Neurology. Approval is pending. Fee includes: registration materials, self-assessment CME (part A), AM & PM break refreshments, and box lunches. Payment must be received prior to admittance to the symposium. Purchase orders are not accepted. Total amount enclosed or to be charged: $___________________________________ PAYMENT Make check payable to: Cleveland Clinic Educational Foundation or charge the following account: q Visa q MasterCard q American Express q Discover Card Number Exp. Date Signature (not valid without signature) If paying by check, registration should be MAILED to: Cleveland Clinic Educational Foundation P.O. Box 931653 • Cleveland, OH 44193-1082 Any questions regarding registrations should be e-mailed to cmeregistration@ccf.org or call 216-448-0777.
    • 21st Annual International Epilepsy Symposia Marriott Cleveland Downtown at Key Center Cleveland, OH Clinical Epileptology Review and Update October 19-20, 2012 Pathology-driven Approach to Epilepsy Surgery: Current State and Future Directions October 21-24, 2012 International Neuroethics Conference: Brain Matters 3 October 24-25, 2012The Cleveland Clinic Foundation 90 Years Logo 4 color process Blue: 100/34/0/2 Green: 100/0/85/24 Neurological Institute, S-40 Cleveland, OH 44195 9500 Euclid Avenue www.ccfcme.org/epilepsy12 In Collaboration With: