Isotonix Advantage - Natural Liquid Vitamins
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Isotonix Advantage - Natural Liquid Vitamins



Isotonic means “same pressure,” bears the same chemical resemblance of the body’s blood, plasma and tears. Isotonix supplements are isotonic. This means that your body accepts it more readily. ...

Isotonic means “same pressure,” bears the same chemical resemblance of the body’s blood, plasma and tears. Isotonix supplements are isotonic. This means that your body accepts it more readily. In fact, Isotonix supplements boast a 95% absorption rate in 10 minutes.



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  • Just the thought of eating food starts the digestive process. For example the salivary glands in our mouths are activated, producing an enzyme that will digest starch into simpler sugar molecules. An enzyme is a substance that speeds up a chemical reaction.
  • The large, hollow organs of the digestive tract contain a layer of muscle that enables their walls to move. The movement of organ walls can propel food and liquid through the system and also can mix the contents within each organ. Food moves from one organ to the next through muscle action called peristalsis. Peristaliss looks like an ocean wave traveling through the muscle. The muscle of the organ contracts to create a narrowing and then propels the narrowed portion slowly down the length of the organ. These waves of narrowing push the food and fluid in front of them through each hollow organ.
  • Swallowed food is pushed into the esophagus, which connects the throat above with the stomach below. The stomach has three mechanical tasks. First, it stores the swallowed food and liquid. It does this by opening and closing ringlike muscles, called sphincter muscles, at the top and bottom of the stomach. Second, it mixes up the food, liquid, and digestive juice produced by the stomach. The third task of the stomach is to slowly empty its contents into the small intestine.
  • After the stomach empties the food and juice mixture, called chime, into the small intestine, the juices of two other digestive organs mix with the food. One of these organs, the pancreas, produces a juice that contains a wide array of enzymes to break down the carbohydrate, fat, and protein in food. A base called sodium bicarbonate is also released to neutralize the acid originating from the stomach.
  • A second organ, the liver, produces yet another digestive juice called bile. Bile is stored between meals in the gallbladder. At mealtime, it is squeed out of the gallbladder, throught he bile ducts, and into the intestine to mix with the fat in food. Bile dissolves fat into the watery contents of the intestine, much like detergents that dissolve grease from a frying pan. After fat is dissolved, it is digested by enzymes from the pancreas and the lining of the intestine.
  • The gastrointestinal tract is a long, muscular tube. If you were to stretch it out to its full length, it would be about thirty feet long. The tube is so specialized that it actually has its own nervous system.
  • 5 Most digested molecules of food, as well as water and minerals, are absorbed through the small intestine. The small intestine contains many folds that are covererd with tiny fingerlike projections called villi. In turn, the villi are covered with microscopic projections called microvilli. These structures create a vast surface area through which nutrients can be absorbed. The surface area is approximately the size of a tennis court. Specialized cells allow nutrients to cross the membrane into the blood, where they are transported to other parts of the body for storage or further chemical change.
  • Bacteria in the colon play a significant role in our defense system from outside threats. In fact, the largest part of our immune system resides in the lining of the digestive tract.

Isotonix Advantage - Natural Liquid Vitamins Isotonix Advantage - Natural Liquid Vitamins Presentation Transcript

  • The Isotonix ® Advantage Mark Lange, Ph.D. Director, Quality Control Market America
    • Understanding Your Digestive System
    • Transporting Nutrients into Cells
    • The Isotonix Delivery System
    • Isotonix Advantage #1,2,3…..
    • Secretes 5 substances mainly:
    • Water – diluent
    • Chloride ions
    • Hydrogen ions
    • Pepsin – proteolytic enzyme (proteins)
    • Intrinsic factor – vitamin B-12 binding protein released by parietal cells
    Hydrochloric acid HCl = pH 1.0 – 2.8
  • Isotonix Advantage #1
    • Nutrients are not exposed to acidic environment of stomach, where they would otherwise degrade.
    • Customer money is not wasted.
  • Isotonix Advantage #2
    • Reduced delivery time.
    • Example: B vitamins for energy
    • Minutes to uptake – not hours
    • ACIDIC FOOD SOLUTION stimulates pancreas to release numerous digestive enzymes in a sodium bicarbonate solution
    • NEUTRALIZATION pH of food solution changed from acidic to nearly neutral
    • BILE is a product of the liver, collected in the gall bladder, and secreted onto the food solution.
    • Contains surfactants that disperse fat.
    • Lipases act on triglycerides, releasing fatty acids.
  • Isotonix Advantage #3
    • Carbon dioxide created by the effervescent reaction reduces the thickness and viscosity of the mucus layer of the intestinal tract, promoting absorption into the cells.
    • Pharm. Res. 1998, vol 15, pp 925-930. “Mechanistic studies on effervescent-induced permeability enhancement.”
  • FOLDS IN THE SMALL INTESTINE Villi Mucosa Sub - Mucosa
  • The Cell Membrane
  • Cell Membrane Barriers
    • Lipid bi-layers are impermeable to most essential molecules and ions.
    • Oxygen, Water, & Carbon Dioxide can freely pass.
    • Many nutrients cannot freely pass.
  • Movement through Differences in Concentration
    • Diffusion is moving molecules from a region of higher concentration to a region of lower concentration.
  • Simple Diffusion
  • Higher concentrations move nutrients into cells Membrane (lipid bi-layer)
  • Isotonix Advantage #4
    • Favorable concentration gradient for absorption of some nutrients. Example: Calcium/Magnesium
    • Nutrients are delivered to the small intestine in a concentrated solution.
  • Facilitated Diffusion
    • Takes place through channels embedded in the membrane.
    • Example: Fructose moved into cell by facilitated diffusion.
  • Active Transport
    • Pumping of molecules or ions through a membrane into a region of higher concentration. It requires a trans-membrane protein and energy input.
    • Example: Amino Acids, ATP, Sodium, Potassium moved into cell by Active Transport.
    • Absorption of nutrients occurs throughout entire length of small intestine (90 – 95% efficient)
    • Calcium absorption occurs as late as ileo-cecal juncture (appendix)  transport into cells via calcium channels
    • Under neutral pH, intrinsic factor binds to vitamin B-12 to form a complex
    • Intrinsic factor/vitamin B-12 complex binds to receptors (specialized docking structures) on intestinal membranes
    • Last 1/3 rd of small intestine is main absorptive site
    • Most nutrients will have been absorbed by the time they reach the large intestine —an additional 3-5% possible.
    • Major functions of colon:
      • Site of bacterial cell growth and residence
      • An estimated 300-400 species or strains of bacteria continue digestion of waste products
      • Regulates water in body
      • Some vitamins produced in low amounts by bacteria and absorbed
    • Bacteria adjust the pH of the colon into the acidic range – prevents overgrowth of harmful bacteria.
    • Continued growth of friendly bacteria help maintain healthy balance.
  • What does “isotonic” mean?
    • ISO = SAME
    • TONIC = Tension or Pressure
    • An Isotonic Cell is a Happy Cell.
  • Cells act like little bags of salty water…..
    • The movement of water in and out of a cell is called “Osmosis.”
    • Cells want the same concentration of dissolved particles (salt) on both sides of the membrane.
  • Isotonix Advantage #5
    • Isotonic solutions are the optimal delivery system.
    • Isotonix products work with – not against – normal body physiology.
  • Composition of Isotonix Delivery System
    • Active ingredients: vitamins, minerals, oligomeric proanthocyanidins (OPC), flavonoids, coenzyme Q10, etc.
    • Base ingredients: fructose, glucose, citric acid, malic acid, calcium sulfate, maltodextrin, silica, potassium bicarbonate
  • Composition of Isotonix Delivery System
    • Glucose and fructose :
      • Sweet-tasting simple sugars
      • Add significant osmotic pressure
      • Caloric value ( ~ 8 cal/serving)
      • Fructose: principle sugar in formula scores 20 out of 100 on glycemic index (i.e., relatively low value)
  • Composition of Isotonix Delivery System
    • Citric acid and malic acid :
      • Adjust pH to acid range (about 3.5 – 5.0)
      • Adjust taste to “citrus” flavor
      • Minor osmotic pressure adjustment
  • Composition of Isotonix Delivery System
    • Calcium sulfate :
      • Desiccant (takes up moisture in powder) / free-flow agent
      • Minor osmotic pressure adjustment
      • Minor nutritive value
  • Composition of Isotonix Delivery System
    • Maltodextrin :
      • Glucose polymer has minor caloric value
      • Powder — bulking agent
      • Prevents citric acid from reacting with potassium bicarbonate and water
      • Thickening and suspending agent in solution
  • Composition of Isotonix Delivery System
    • Potassium bicarbonate :
      • Potassium and bicarbonate ions have significant osmotic pressure
      • Helps adjust and buffer pH
      • Release of CO 2 stirs liquid
  • Isotonix Advantage #6
    • Isotonix offers an alternative to pills.
    • Survey shows 40% of American adults have experienced difficulty swallowing pills
    • The survey of 679 adults (513 ages 18-64, 166 age 65 and older) was funded by the US affiliate of Germany's Schwarz Pharma.
  • Isotonix Advantage #7
    • People with stomach and esophageal challenges benefit from Isotonix delivery.
      • Acid reflux sufferers
      • Bariatric patients
      • Hiatal Hernia (stomach protrudes up through diaphragm)
      • People who have trouble swallowing
      • Elderly (reduced acid production)
  • Conclusion
    • Isotonix ® product line offers customers a wide selection of nutrient combinations with the advantages of isotonic delivery.
    • Isotonix ® is the logical choice of those seeking fast and optimal nutrient uptake.