SlideShare is now on Android. 15 million presentations at your fingertips.  Get the app

×
  • Share
  • Email
  • Embed
  • Like
  • Save
  • Private Content
 

Race against the sequencing machine: processing of raw DNA sequence data at the Genomics Core

by Senior scientist bio-informatics at Galapagos on Sep 29, 2011

  • 1,245 views

Race against the sequencing machine: processing of raw DNA sequence data at the Genomics Core ...

Race against the sequencing machine: processing of raw DNA sequence data at the Genomics Core
by dr. Luc Dehaspe - Genomics Core, UZ Leuven

To grow and function, living organisms unconsciously and continuously read instructions from the DNA sequence in each cell. Thanks to the advances in DNA sequencing technology, scientists are increasingly able to consciously read along. In 2001, sequencing efforts resulted in a first draft of human genome. Since then, the capacity of the DNA reading machines has doubled every six months on average. While the first human genome sequencing project took years of worldwide collaboration, multiple genomes can now be sequenced in 10 days on a single machine at a service facility such as the Genomics Core.
Each sequencing run gives rise to a few terabytes of raw data that, using bioinformatics techniques, must be processed in time, before the next bunch of data arrives.
I will discuss bioinformatics techniques that are commonly used in the Genomics Core and that have a chance to survive another generation of sequencing machines. <\br>A crucial feature of these techniques is that they keep up with the sequencing machines by creating sub-tasks that are distributed over an extensible network of computers.

Statistics

Views

Total Views
1,245
Views on SlideShare
996
Embed Views
249

Actions

Likes
2
Downloads
0
Comments
0

1 Embed 249

http://mellfire.ugent.be 249

Accessibility

Categories

Upload Details

Uploaded via SlideShare as Microsoft PowerPoint

Usage Rights

© All Rights Reserved

Report content

Flagged as inappropriate Flag as inappropriate
Flag as inappropriate

Select your reason for flagging this presentation as inappropriate.

Cancel
Post Comment
Edit your comment

Race against the sequencing machine: processing of raw DNA sequence data at the Genomics Core Race against the sequencing machine: processing of raw DNA sequence data at the Genomics Core Presentation Transcript