Founded May 15, 2006
Institute for
              NanoBioTechnology
                    RESEARCH: at the interface
                    of engine...
Where is the Institute for
                  NanoBioTechnology?

                        Johns Hopkins                    ...
INBT: Research Foci

Nanoscience / Nanotechnology        Cellular & Molecular Dynamics
 “Basic Engineering Science”       ...
Seed Grants for Diagnostics
          Research- $20,000
• “Tumor imaging by silica nanoparticles: binding to prostate
  sp...
Seed Grants for Therapeutics
     Research- $15,000-$25,000
•    “Corrolazine nanoparticles for photodynamic therapy and m...
Grants for Research in Cellular
  and Molecular Dynamics-
           $75,000
• “Nano- and micro-scale analysis of PKA regu...
INBT-Funded Pilot Projects
      for Health & Environment
• Influence of surface chemistry on the fate and environmental i...
EDUCATION:
     Training the Next
        Generation

•   NanoBioMed Training Program sponsored by
    the Howard Hughes M...
Highlights:
    Annual NanoBio Symposium
• May 1-2, 2008 at the Johns Hopkins School of
  Medicine
• 500 people over two d...
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General Overview of INBT

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This is the presentation generally given by our director or by one of the staff to orient people to what INBT is all about.

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General Overview of INBT

  1. 1. Founded May 15, 2006
  2. 2. Institute for NanoBioTechnology RESEARCH: at the interface of engineering, the sciences, medicine and public health EDUCATION : train the next generation of OUTREACH: scientists & create an INBT entrepreneurial engineers skilled in many areas environment; tech transfer To learn more visit: http://inbt.jhu.edu
  3. 3. Where is the Institute for NanoBioTechnology? Johns Hopkins 158 affiliated School of Medicine faculty from 5 divisions Whiting School of Bloomberg School of Engineering Public Health INBT Applied Krieger School of Physics Lab Arts and Sciences Offices located at 214 Maryland Hall on the Homewood Campus
  4. 4. INBT: Research Foci Nanoscience / Nanotechnology Cellular & Molecular Dynamics “Basic Engineering Science” “Basic Biological Science” Health & Therapeutics Diagnostics Environment “Clinical Science” “Clinical Science” “Public Health”
  5. 5. Seed Grants for Diagnostics Research- $20,000 • “Tumor imaging by silica nanoparticles: binding to prostate specific membrane antigen” Howard Katz (MatSc) & Ronnie Mease (Radiology) • “Diagnosing colon cancer risk through direct experimentation on biopsied cells” Andre Levchenko (BioMed) & Andrew Feinberg (Medicine/Oncology) • “Nanomechanical techniques for cancer diagnosis” Sean Sun (MechE), Greg Bowman (Biophysics) & Peter Searson (MatSc) • “Innovative technologies to study mechanisms of inflammation- induced CNS axonal degeneration” Nitish Thakor (BioMed), Arun Venkatesan (Neurology) & Avindra Nath (Neurology) • “An integrated microfluidic nanosensor platform for point mutation detection of cancers” Jeff Wang (MechE) & Le-Ming Shih (Pathology)
  6. 6. Seed Grants for Therapeutics Research- $15,000-$25,000 • “Corrolazine nanoparticles for photodynamic therapy and magnetic resonance imaging” David Goldberg (Chemistry), Jeff Bulte (Radiology), & Anirban Maitra (Pathology/Oncology) • “Bone-targeted biodegradable nano-spheres for localized treatment of skeletal disease” Scott Kominsky (Orthopaedic Surgery/Oncology), Justin Hanes (Chemical & Biomolecular Eng), & Kristy Weber (Orthopaedic Surgery/Oncology) • “Selective prodrug activation in cancer cells using protein switches” Marc Ostermeier (Chemical & Biomolecular Engr), James Eshleman (Pathology/Oncology), & Craig Townsend (Chemistry) • “Quantum dots as artificial antigen-presenting cells (aAPC) for tumor immunotherapy” Jonathan Schneck (Pathology), & Michael Edidin (Biology) • “In vivo evaluation of sugar-SCFA nanoparticles” Kevin Yarema (Biomedical Engr) & Henry Brem (Neurosurgery)
  7. 7. Grants for Research in Cellular and Molecular Dynamics- $75,000 • “Nano- and micro-scale analysis of PKA regulation of cell locomotion” Andre Levchenko (Biomedical Eng) & Jin Zhang (Pharmacology and Neuroscience) • “Glyco-nanoparticles targeting dendritic cells for enhanced immune tolerance” Y. C. Lee (Biology), Hai-Quan Mao (Materials Science & Eng) & Shau-Ku Huang (Medicine) • “Polymeric nanoparticle drug delivery systems for the development of an immunogenic ovarian tumor cell-based vaccine” Chien-Fu Hung (Pathology) & Justin Hanes (Chemical Eng)
  8. 8. INBT-Funded Pilot Projects for Health & Environment • Influence of surface chemistry on the fate and environmental impact of carbon nanotubes in aquatic environments, Bill Ball (WSE), Howard Fairbrother (KSAS) • Exposure assessment: Probing size-dependent effects on the concentration and speciation of transition metals in particulate matter, Alison Geyh (BSPH) & Howard Fairbrother (KSAS) • Generation of dissolved toxic species through reaction of manganese oxide nanoparticles with biofluids, Joe Bressler (BSPH & KKI), Alan Stone (WSE) & David Veblem (KSAS) • Nanomaterials as transporters of toxic agents into cell systems, Ellen Silbergeld (BSPH) & Howard Katz (WSE) • Toxicological evaluation of nanoparticles in a mouse model of chronic lung disease, Shyam Biswal (BSPH) & Justin Hanes (WSE)
  9. 9. EDUCATION: Training the Next Generation • NanoBioMed Training Program sponsored by the Howard Hughes Medical Institute • Physical & Biomolecular Foundations for Designing Nanoprobes for Biology and Medicine IGERT sponsored by the National Science Foundation • Highly selective summer REU funded by NSF To learn more visit: http://inbt.jhu.edu
  10. 10. Highlights: Annual NanoBio Symposium • May 1-2, 2008 at the Johns Hopkins School of Medicine • 500 people over two days • “Nanotechnology for Cancer” workshop co- hosted by Sidney Kimmel Comprehensive Cancer Center with 10 Hopkins faculty presenters • Speakers from Harvard, Rice, NIH, Woodrow Wilson Center, University at Buffalo • 100+ posters • 30+ businesses

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