Your SlideShare is downloading. ×
  • Like
  • Save
Chip In A Pill
Upcoming SlideShare
Loading in...5
×

Thanks for flagging this SlideShare!

Oops! An error has occurred.

×

Now you can save presentations on your phone or tablet

Available for both IPhone and Android

Text the download link to your phone

Standard text messaging rates apply
Published

One of the morning repor reviews which I did during my rotation and Allergan, Inc.

One of the morning repor reviews which I did during my rotation and Allergan, Inc.

  • Full Name Full Name Comment goes here.
    Are you sure you want to
    Your message goes here
    Be the first to comment
    Be the first to like this
No Downloads

Views

Total Views
615
On SlideShare
0
From Embeds
0
Number of Embeds
1

Actions

Shares
Downloads
0
Comments
0
Likes
0

Embeds 0

No embeds

Report content

Flagged as inappropriate Flag as inappropriate
Flag as inappropriate

Select your reason for flagging this presentation as inappropriate.

Cancel
    No notes for slide

Transcript

  • 1. A CHIP-PILL?!! Maryana Arsanious CPQS weekly review December 3 rd , 2010
  • 2. Chip in a pill ??!!!
    • A “smart-pill”, is a new technology which has been developed by Proteus Biomedical of Redwood City, California
    • It is a “pill” which contains a chip inside and upon ingestion, the chip gets activated by stomach acid
    • The chip goes into the patient’s skin, where there’s an activating system in a patch on the patient’s shoulder
    • When it’s activated, the chip sends data to a receiver which could be located at the patient’s cell phone or at the doctor’s office (through the internet)
  • 3.  
  • 4. Smart-pill vs. Raisin vs. ChipSkin??!!!
    • Smart-pill : A tablet which contains a chip that is ingested by patient
    • Raisin : A smart pill, which also releases medications while holding the chip inside
    • ChipSkin : A smart pill, which contains an implantable device that does not get deactivated by body fluids. Similar to the one in pacemakers.
  • 5. What does it do?
    • Physician:
    • Gives the physician access to patient’s chip instantly at any given time to help him stay updated with patient’s health status
    • Patient:
    • Sends a text message to the patient in case:
    • Patient forget to take medication
    • Patient is not taking medication as directed
  • 6. Where is it now?
    • In January, Norvartis spent ~$24 million to ensure its access to the device made by Proteus Biomedical.
    • “ Joe Jimenez, head of pharmaceuticals at Novartis, said tests using the system – which broadcasts from the “chip in the pill” to a receiver on the shoulder – on 20 patients using Diovan, a drug to lower blood pressure, had boosted “compliance” with prescriptions from 30 per cent to 80 per cent after six months ”
    • (Jack, A. Financial Times . Novartis chip to help ensure bitter pills are swallowed, 2010 http://www.ft.com/cms/s/0/c1473442-a6f4-11de-bd14 00144feabdc0.html#axzz15OLuY0CD )
  • 7. Where is it now? (cont.)
    • Novartis is not planning to carry out full-scale clinical trials or test for safety since the chip will be added to currently existing medications
    • Novartis’s plan is to carry out a “bio-equivalency” study to test for effectiveness of the device
    • The first “chip-in-pill” is expected to be available in a pharmacy by 2012
  • 8. Purpose??!!
    • To make sure patient takes the right medication, the right dose at the right time
    • To insure better compliance of patients, which saves millions of dollars of unnecessary costs
    • To help monitor physiological signs of patients
    • To help study the true efficacy of drugs
    • To eliminate the claim made by some pharmaceutical companies that lack of efficacy is due to lack of compliance.
  • 9. Where will it go next?!!
    • The chip will be used to collect internal physiological information such as heart rate, body temperature, blood pressure… in the real time.
    • Novartis is looking into using the chip as a means of identifying whether the medications are working properly
    • By using this property, doctors will be more able to identify a problem at the exact moment, and the pharmacodynamics of the drug at the moment.
    • http://video.forbes.com/fvn/breakout/tracking-your-health
  • 10. Current Concerns
    • Privacy: Patient’s personal information is transmitted through wireless connections
    • Safety, especially with no clinical trials conducted
    • Higher medication price
    • One physician vs. multiple patients with multiple conditions requiring multiple medications for each
  • 11. References
    • Hirschler, B. Reuters, Look out, your medicine is watching you, 2009 . http://www.reuters.com/article/idUSTRE6A754720101108
    • Proteus Biometrics, Proteus Ingestible Microchip Hits Clinical Trials, 2009 . http://www.proteusbiomed.com/2009/06/08/proteus-ingestible-microchip-hits-clinical-trials/
    • Jack, A. Financial Times . Novartis chip to help ensure bitter pills are swallowed, 2010 http://www.ft.com/cms/s/0/c1473442-a6f4-11de-bd14-00144feabdc0.html#axzz15OLuY0CD