Opportunities for Neuroeconomists at the
National Institute on Aging
and through NIH-wide initiatives
Lis Nielsen
nielsenl...
Research Priorities at BSR/NIA
• Neuroeconomics and Decision Research *
• Social Neuroscience of Aging *
• Behavioral Econ...
Understanding NIA
• Aging-relevant research is NOT just the study of older
people
• Lifecourse perspective – aging as a pr...
Resources at NIA
• Recent RFAs (inactive) reflect our ongoing interest in:
– Neuroeconomics of Aging
http://grants.nih.gov...
Emerging Opportunities at NIA
National Institute on Aging
http://hrsonline.isr.umich.edu/
• Genotyping 20,000 individuals ...
Emerging Opportunities at NIA
National Institute on Aging
• Network to advance Decision Neuroscience of Aging
• Over five ...
“In this economy, it’s crucial to begin every
sentence with ‘in this economy.’”
NIH-wide initiatives
Science of Behavior Change
http://nihroadmap.nih.gov/behaviorchange/index.asp
OppNet
http://oppnet.ni...
Science of Behavior Change
NIH Roadmap Program
• Trans-NIH initiative to focus on approaches to improving
initiation and m...
Poor Health Behaviors Kill
Schroeder et al. (2007, NEJM)
Behavior Change is Powerful
A 7% weight reduction and 2.5 hour per week activity increase led to a
58% reduction in the cu...
Balkanization of Behavior Change
Neuroscience
Behavioral
Science
Economics
Policy
Smoking
Cessation
Genetics
Medication
Ad...
Emergence of Transdisciplinary Science
Neuroscience
Behavioral
Science
Economics
Policy
Behavior
Change
Genetics
Relevant ...
SOBC Roadmap RFA-RM-10-002
Focused on Mechanisms of Change
Mechanisms of decision-making
e.g., risk perception, temporal d...
OppNet: Mission and GoalsOppNet: Mission and Goals
• To strengthen basic Behavioral and Social Science Research (b-
BSSR) ...
OppNet FY2011 FOAs
RFA-AG-11-010 BASIC RESEARCH ON SELF-REGULATION (R21)
2 yr; $275K total direct costs. Due Date: January...
Research Community Input Shapes OppNet’s Directions:
OppNet Meeting: Expanding Opportunities in
Basic Behavioral and Socia...
Opportunities for Neuroeconomists at the National Institute ...
Opportunities for Neuroeconomists at the National Institute ...
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  • 130 Participants chose Key Themes
    Integrated, multi-level approaches to change
    Need to target behavior “bundles” at once
    Behavior in a developmental perspective
    Environmental context of behavior and change
    New methods and measurement
    Better understanding of basic mechanisms
  • About 10 applications funded under this one time initiative. Investigator initiated applications on themes of the meeting and RFA remain of high interest to all the participating institutes.
  • Launched in November 2009. 10 million in ARRA funds. $20 million in FY 2011 funds, $30 million annually in years following over this initial 5 year period.
  • RFA-CA-10-017 (1) accelerate, expand, and/or strengthen the scope of investigation of a specific b-BSSR research domain through the integration of disparate approaches from b-BSSR and allied disciplines; or (2) increase the sophistication of theoretical, methodological, and analytical approaches in b-BSSR.
    RFA-NR-11-002 Such approaches would include establishment of new collaborations for cross-disciplinary translation of knowledge in the basic behavioral and social sciences. These interdisciplinary educational programs are likely to involve active collaborations or special arrangements between institutions and/or departments such as those with research center support grants, schools of public health, departments of community and preventive medicine, and other departments and institutions that have the necessary expertise and resources to fulfill the objectives of this FOA. Any of these entities may act as the applicant organization, as long as the qualifications of the participants and the focus of the program are on the education of early-stage researchers to incorporate basic behavioral and social science principles, theories and methods into their research projects. Applicants should seek to conduct small research grants relevant (but not limited) to the following b-BSSR research areas: 
    INCLUDING:
    Health Behavior - New strategies to improve and sustain behavior change such as Basic behavioral processes such as habit formation, the development of automatic associations including cognitive automaticity, and non-goal directed motivational processes.  These may include social and contextual factors that could be integrated with the cognitive neurosciences to improve understanding of how behaviors are maintained over time.
    Self Regulation – Refine measures and theoretical conceptualizations of basic processes of social, personality and developmental psychology, including, cognition, emotion and behavior.  For example, approaches may utilize approaches combining self-regulation with the fields of economics and neuroscience to map processes over time and across developmental life periods.
  • Opportunities for Neuroeconomists at the National Institute ...

    1. 1. Opportunities for Neuroeconomists at the National Institute on Aging and through NIH-wide initiatives Lis Nielsen nielsenli@nia.nih.gov Division of Behavioral and Social Research (BSR), NIA http://www.nia.nih.gov/ResearchInformation/ExtramuralPrograms/BehavioralAndSocialResearch/ National Institute on Aging
    2. 2. Research Priorities at BSR/NIA • Neuroeconomics and Decision Research * • Social Neuroscience of Aging * • Behavioral Economics • Mechanisms of Behavior Change * • Integrating genetics into behavioral models • Economic Phenotypes * • Economics of Aging (Health and Retirement) • Training Interdisciplinary Scientists – need good K and F32 applicants bridging econ/psych/neuroscience *review National Institute on Aging
    3. 3. Understanding NIA • Aging-relevant research is NOT just the study of older people • Lifecourse perspective – aging as a process that unfolds; early life factors impacting trajectories of health and (subjective/economic) well-being in mid-late life • Aging-relevant phenomena – self-regulation, motivation, delay discounting, susceptibility to fraud, social influences on decision making – through a lifecourse lens • Changing demographic of population impacts structure of institutions, policies, and choices of individuals National Institute on Aging
    4. 4. Resources at NIA • Recent RFAs (inactive) reflect our ongoing interest in: – Neuroeconomics of Aging http://grants.nih.gov/grants/guide/rfa-files/RFA-AG-06-011.html – Social Neuroscience of Aging http://grants.nih.gov/grants/guide/rfa-files/RFA-AG-09-006.html • Priority areas for research training http://www.nia.nih.gov/ResearchInformation/ExtramuralPrograms/BehavioralAndSocialResearch/ PriorityAreas.htm • Workshop Reports highlight needs for future research in these and related areas, including genetic approaches: http://www.nia.nih.gov/ResearchInformation/ExtramuralPrograms/BehavioralAndSocialResearch/ CMW.htm National Institute on Aging
    5. 5. Emerging Opportunities at NIA National Institute on Aging http://hrsonline.isr.umich.edu/ • Genotyping 20,000 individuals with longitudinal survey data on health and economic behaviors • Lab-based methods (imaging) most likely to find heritable phenotypes closely linked to biology • But only very large samples will allow genetic model estimation and replication • Critical need for lab-survey interface around economic phenotypes
    6. 6. Emerging Opportunities at NIA National Institute on Aging • Network to advance Decision Neuroscience of Aging • Over five years this network grant will support scientific meetings, intensive training workshops for researchers at all stages, and a pilot grant competition for researchers new to the field. • Core Network Personnel: Laura Carstensen (Stanford), Samuel McClure (Stanford), Gregory Samanez Larkin (Vanderbildt), Camelia Kuhnen (Northwestern), David Laibson (Harvard)
    7. 7. “In this economy, it’s crucial to begin every sentence with ‘in this economy.’”
    8. 8. NIH-wide initiatives Science of Behavior Change http://nihroadmap.nih.gov/behaviorchange/index.asp OppNet http://oppnet.nih.gov Health Economics http://nihroadmap.nih.gov/healtheconomics/ National Institute on Aging
    9. 9. Science of Behavior Change NIH Roadmap Program • Trans-NIH initiative to focus on approaches to improving initiation and maintenance of positive health behaviors • Leveraging advances in emerging basic behavioral and social science domains • NIH Directors approved Roadmap funding for developmental activities including planning meetings. • DPCPSI, FIC, NCCAM, NCI, NHGRI, NHLBI, NIA, NIAAA, NIAID, NIAMS, NICHD, NIDA, NIDCR, NIDDK, NIGMS, NIMH, NINDS, NINR, OBSSR National Institute on Aging
    10. 10. Poor Health Behaviors Kill Schroeder et al. (2007, NEJM)
    11. 11. Behavior Change is Powerful A 7% weight reduction and 2.5 hour per week activity increase led to a 58% reduction in the cumulative incidence of Type 2 diabetes in insulin-resistant individuals (Diabetes Prevention Program Research Group, 2002).
    12. 12. Balkanization of Behavior Change Neuroscience Behavioral Science Economics Policy Smoking Cessation Genetics Medication Adherence Increase Exercise Moderate Drinking Financial Planning 17 different ICs support research in (very specific areas of) behavior change.
    13. 13. Emergence of Transdisciplinary Science Neuroscience Behavioral Science Economics Policy Behavior Change Genetics Relevant science is rapidly emerging but is not optimally focused on Behavior Change. Behavior Genetics BehavioralEconomics Neuroeconomics Cognitive/Affective Neuroscience
    14. 14. SOBC Roadmap RFA-RM-10-002 Focused on Mechanisms of Change Mechanisms of decision-making e.g., risk perception, temporal discounting Mechanisms of control and self-monitoring: e.g., executive function, interoceptive awareness, emotion regulation; Mechanisms of social and cultural transmission of behaviors and of interpersonal transaction: e.g., contagion, mimicry, modeling, norms, peer effects, competition; Structural mechanisms: e.g., choice architectures, defaults, environmental affordances; Neurobiological and genetic mechanisms: e.g., related to these processes, including those associated with individual differences in biophysiologic capacity or psychological resilience/vulnerability. National Institute on Aging
    15. 15. OppNet: Mission and GoalsOppNet: Mission and Goals • To strengthen basic Behavioral and Social Science Research (b- BSSR) across NIH institutes, innovating beyond existing investments • Build a body of knowledge about the nature of behavior and social systems, focused on basic mechanisms of behavior and social processes • Three domains: • Behavioral and Social Processes (e.g., learning, social cognition, group processes, migration patterns) • Biobehavioral and Biosocial Research (e.g., social, cognitive, affective and economic neurosciences) • Methodology and measurement (e.g., data collection, modeling, research design)
    16. 16. OppNet FY2011 FOAs RFA-AG-11-010 BASIC RESEARCH ON SELF-REGULATION (R21) 2 yr; $275K total direct costs. Due Date: January 6, 2011 * Related to SOBC 1) to precisely identify and operationally reconcile the basic processes and mechanisms involved in self-regulation of cognition, emotion, and behavior, and refine their measurement and theoretical conceptualizations, 2) to assess relations among various self-regulatory functions and their sub-components, and 3) to systematically characterize changes in self-regulatory functions over time, across different social and environmental contexts, and across the lifespan CAPACITY BUILDING RFA-CA-10-017 Due Date: December 14, 2010 Scientific meetings for creating interdisciplinary research teams in emerging b-BSSR (R13) 2 year; $50K/year direct RFA-NR-11-002 Due Date: January 6, 2011 Short-term Interdisciplinary Research Education Program for New Investigators (R25) 1 year; $150K direct costs.
    17. 17. Research Community Input Shapes OppNet’s Directions: OppNet Meeting: Expanding Opportunities in Basic Behavioral and Social Science Research Thursday and Friday, October 28-29, 2010 Hyatt Regency Washington on Capitol Hill 400 New Jersey Avenue, NW Washington, DC 20001 Free registration Visit OppNet’s website for more information: http://oppnet.nih.gov

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