intro_neuro_S2004.ppt

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intro_neuro_S2004.ppt

  1. 1. BIOLOGY 490 NEUROBIOLOGY Dr. Elba E. Serrano eserra@crl.nmsu.edu http://biology-web.nmsu.edu/serrano/courses/490s2004/490s2004.html
  2. 2. TODAY TASKS: • SEND EMAIL TO eserra@crlnmsu.edu with Bio 490 student in address line • HANDOUTS STUDENT INFORMATION FORM (YELLOW) RECITATION SELECTION (SALMON) SYLLABUS (BLUE) • PLEASE FILL OUT STUDENT INFORMATION FORM REVIEW SYLLABUS INTRODUCTION TO BRAIN AND NERVOUS SYSTEM
  3. 3. BIO 490 Covers fundamental principles of nervous system structure and function Neurobiologists are interested in the biological basis of human thought, behavior, and emotion Neurobiology is a central area of modern biomedical research in part because one of five persons will experience a disorder of the nervous system at some point in their life.
  4. 4. BIO 490 This course is particularly relevant for students seeking careers in biomedical fields such as medicine, neuroscience, pharmacology, and cancer research. It also will be of interest to students interested in the biological basis of consciousness and with curiosity about how the mind works. Careers in NS: genetics, anatomists, biochemists, physiologists. engineers, chemists and computer scientists
  5. 5. COURSE GOALS This course will integrate concepts from other courses Review basic electricity and circuits from physics Math: logarithms and exponents Biochemistry Genetics
  6. 6. COURSE GOALS This course will integrate concepts from other courses Review basic electricity and circuits from physics Math: logarithms and exponents Biochemistry Genetics By end of semester students will (hopefully!) have a working vocabulary in neuroscience have a basic knowledge in a full spectrum of neuroscience areas from genes and cells to sensory processing and behavior
  7. 7. COURSE GOALS By end of semester students will (hopefully!) have a greater understanding of how the brain works be able to read and comprehend an article in the neuroscience primary literature and understand WHY the research question was under investigation have identified an area of personal interest in neuroscience
  8. 8. COURSE GOALS By end of semester students will (hopefully!) have a greater understanding of how the brain works be able to read and comprehend an article in the neuroscience primary literature and understand WHY the research question was under investigation have identified an area of personal interest in neuroscience be ready for advanced graduate and medical school courses HAVE KNOWLEDGE OF BASIC NEUROSCIENCE AND ITS APPLICATIONS FOR TREATING DISEASES AND DISORDERS OF THE NERVOUS SYSTEM
  9. 9. DISEASES & THE NERVOUS SYSTEM
  10. 10. DISEASES & THE NERVOUS SYSTEM CAUSES Stress, injury, gene mutations can damage the neurons and glial cells of the brain Injury to the brain can disrupt sensation, movement, thought, and even cause death
  11. 11. DISEASES & THE NERVOUS SYSTEM CAUSES Stress, injury, gene mutations can damage the neurons and glial cells of the brain Injury to the brain can disrupt sensation, movement, thought, and even cause death 100’s of disorders affect the brain & nervous system Many share similar mechanism of disease When cells in the brain die they are not easily replaced
  12. 12. DISEASES & THE NERVOUS SYSTEM • Neural stem cells may be able to provide therapuetic treatment for strokes spinal cord injuries brain tumors Parkinson's disease multiple sclerosis many inherited disorders
  13. 13. Diseases of the Nervous System 1998 Disease cases cost cost/case Addiction 30 mil $160 bil $ 5,333 Chronic pain 90 mil $100 bil $ 1,100 Alzheimers* 4 mil $90 bil $22,500 Hearing loss* 28 mil $56 bil $ 2,000 Blindness/vision loss* 13 mil $38 bil $ 2,900 Traumatic CNS injury 1.3 mil $35 bil $33,000 Schizophrenia 2 mil $33 bil $16,250 Depressive disorders 18 mil $30 bil $ 1,666 Stroke* 3 mil $25 bil $ 8,333 Parkinson’s* 0.5 mil $6 bil $12,000 Multiple sclerosis 0.3 mil $5 bil $16,667 Epilepsy 2.5 mil $3.5 bil $ 1,400
  14. 14. INTRIGUING QUESTIONS:
  15. 15. INTRIGUING QUESTIONS: WHAT IS THE RELATIONSHIP BETWEEN BRAIN AND MIND?
  16. 16. INTRIGUING QUESTIONS: WHAT IS THE RELATIONSHIP BETWEEN BRAIN AND MIND? WHAT IS CONSCIOUSNESS?
  17. 17. INTRIGUING QUESTIONS: WHAT IS THE RELATIONSHIP BETWEEN BRAIN AND MIND? WHAT IS CONSCIOUSNESS? CAN THOUGHTS AND EMOTIONS BE EXPLAINED BY CIRCUITS, CELLS AND GENES?
  18. 18. INTRIGUING QUESTIONS: WHAT IS THE RELATIONSHIP BETWEEN BRAIN AND MIND? WHAT IS CONSCIOUSNESS? CAN THOUGHTS AND EMOTIONS BE EXPLAINED BY CIRCUITS, CELLS AND GENES? WHAT IS A HUMAN BEING?
  19. 19. NEURON AND GLIAL CELL STRUCTURE CELL DIVERSITY, MEMBRANES, ORGANELLES NEURAL SIGNALLING ELECTRICAL PROPERTIES OF NEURONS NEURAL COMMUNICATION CHEMICAL AND ELECTRICAL SYNAPSES NEUROTRANSMITTERS AND RECEPTORS NEURAL ORGANIZATION: CNS & PNS BRAIN CHEMISTRY AND BEHAVIOR MENTAL HEALTH FEAR, AGGRESSION SENSORY SYSTEMS CHEMICAL: OLFACTION AND TASTE OPTICAL: VISION MECHANICAL: AUDITION, BALANCE, SOMATOSENSORY TOPICS
  20. 20. NEURAL DEVELOPMENT NEURAL INDUCTION GENE EXPRESSION WIRING THE BRAIN BRAIN RHYTHMS SEX AND THE BRAIN LEARNING AND MEMORY TOPICS
  21. 21. http://biology-web.nmsu.edu/serrano/courses/490s2004/490s2004.html

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